{"title":"Mitral regurgitation in atrial fibrillation: Is a simple repair enough to tackle a complex problem?","authors":"Sohaihra Khan (MBBS) , Ruba Javed (MBBS) , Shafin Amin (MBBS)","doi":"10.1016/j.jjcc.2024.12.002","DOIUrl":"10.1016/j.jjcc.2024.12.002","url":null,"abstract":"","PeriodicalId":15223,"journal":{"name":"Journal of cardiology","volume":"86 1","pages":"Pages 100-101"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How to demonstrate clinical implication of ECPELLA strategy in patients with acute myocardial infarction complicated with cardiogenic shock","authors":"Masaki Nakagaito MD, PhD, Teruhiko Imamura MD, PhD, FJCC","doi":"10.1016/j.jjcc.2025.02.019","DOIUrl":"10.1016/j.jjcc.2025.02.019","url":null,"abstract":"","PeriodicalId":15223,"journal":{"name":"Journal of cardiology","volume":"86 1","pages":"Page 115"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prognostic values of proteinuria in patients with acute heart failure","authors":"Yuka Akama MD , Yuya Matsue MD, PhD , Daichi Maeda MD, PhD , Taishi Dotare MD, PhD , Tsutomu Sunayama MD, PhD , Takashi Iso MD, PhD , Yudai Fujimoto MD , Taisuke Nakade MD , Shoichiro Yatsu MD, PhD , Sayaki Ishiwata MD, PhD , Yutaka Nakamura MD , Shoko Suda MD, PhD , Takao Kato MD, PhD , Masaru Hiki MD, PhD , Takatoshi Kasai MD, PhD, FJCC , Tohru Minamino MD, PhD, FJCC","doi":"10.1016/j.jjcc.2025.01.010","DOIUrl":"10.1016/j.jjcc.2025.01.010","url":null,"abstract":"<div><h3>Background</h3><div>Renal dysfunction is significantly associated with poor prognosis in patients with heart failure. However, the prognostic significance of proteinuria as a potential marker of an impaired glomerular filtration barrier in acute heart failure (AHF) remains unclear. We aimed to investigate the prognostic value of urinary protein/creatinine ratio (PCR) in patients with AHF.</div></div><div><h3>Methods</h3><div>Urinary protein levels measured at admission were adjusted for urinary creatinine concentrations in 346 patients (75 ± 13 years; 61 % men) with AHF. Patients were categorized based on urinary PCR, adhering to the Japanese chronic kidney disease (CKD) guideline cut-offs for CKD staging: A1 (<0.15 g/gCr), A2 (0.15–0.49 g/gCr), and A3 (≥0.5 g/gCr). The primary endpoint was all-cause mortality.</div></div><div><h3>Results</h3><div>Overall, there were 85, 126, and 135 patients in the A1, A2, and A3 groups, respectively. Groups A2 and A3 were associated with lower hemoglobin levels, higher blood urea nitrogen and N-terminal pro-B-type natriuretic peptide levels, and poor renal function. Moreover, groups A2 and A3 had high cystatin C, alpha 1 microglobulin, and urinary liver-type fatty acid-binding protein (L-FABP) levels. Urinary PCR correlated more with tubular markers, alpha 1-microglobulin, and L-FABP than with the glomerular marker cystatin C. Over a median follow-up period of 434 (interquartile range: 89–753) days, 72 deaths occurred. Elevated urinary PCR was associated with higher mortality rates (log-rank test, <em>p</em> < 0.001), even after adjusting for other variables [A2 vs. A1: hazard ratio (HR) 2.59, 95 % confidence interval (CI) 0.71–9,55, <em>p</em> = 0.15; A3 vs. A1: HR 4.40, 95 % CI 1.17–16.6, <em>p</em> = 0.029].</div></div><div><h3>Conclusions</h3><div>Elevated urinary PCR is more prevalent in patients with AHF and is associated with a higher risk of all-cause mortality, independent of covariates, including glomerular function. Thus, urinary PCR at admission should provide prognostic information independent of glomerular function.</div></div>","PeriodicalId":15223,"journal":{"name":"Journal of cardiology","volume":"86 1","pages":"Pages 83-87"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Paradoxical outcomes in very severe aortic stenosis following TAVI","authors":"Mesut Gitmez MD , Mehmet Kadri Akboga MD","doi":"10.1016/j.jjcc.2025.02.014","DOIUrl":"10.1016/j.jjcc.2025.02.014","url":null,"abstract":"","PeriodicalId":15223,"journal":{"name":"Journal of cardiology","volume":"86 1","pages":"Pages 112-113"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advances in the management of out-of-hospital cardiac arrest: A clinical review","authors":"Kazuya Tateishi MD, Yuichi Saito MD, Yoshio Kobayashi MD, PhD, FJCC","doi":"10.1016/j.jjcc.2025.04.010","DOIUrl":"10.1016/j.jjcc.2025.04.010","url":null,"abstract":"<div><div>Despite considerable advances in the management, the prognosis of patients resuscitated from out-of-hospital cardiac arrest (OHCA) remains poor. To standardize clinical practice patterns and to improve outcomes, the guidelines provide scientific statements. It is challenging to develop and establish novel diagnostic and therapeutic strategies in randomized controlled trials in patients with OHCA. Nonetheless, important randomized data have been recently published in the field of resuscitation science. This review article provides an overview of updates on OHCA and resuscitation, focusing on key topics since 2020.</div></div>","PeriodicalId":15223,"journal":{"name":"Journal of cardiology","volume":"86 1","pages":"Pages 25-31"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zheng-Qi Song MD , Xin-Yu Lu MD , Yu-Peng Xu MD , Hui Lin MD , Yi-He Chen MD, PhD
{"title":"Author's reply to “How to indicate left atrial posterior wall isolation adjunctive to conventional pulmonary vein isolation in patients with atrial fibrillation”","authors":"Zheng-Qi Song MD , Xin-Yu Lu MD , Yu-Peng Xu MD , Hui Lin MD , Yi-He Chen MD, PhD","doi":"10.1016/j.jjcc.2025.02.015","DOIUrl":"10.1016/j.jjcc.2025.02.015","url":null,"abstract":"","PeriodicalId":15223,"journal":{"name":"Journal of cardiology","volume":"86 1","pages":"Page 107"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143433234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The difference of gas exchange pulmonary arterial capacitance with postural change between chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension","authors":"Shota Soma PT, MSc , Nobuhiro Yaoita MD, PhD , Taijyu Satoh MD, PhD , Kotaro Nochioka MD, PhD, FJCC , Saori Yamamoto MD, PhD , Haruka Sato MD, PhD , Hiroyuki Takahama MD, PhD, FJCC , Hideaki Suzuki MD, PhD , Masashi Takeuchi PT, PhD , Satoru Ebihara MD, PhD , Satoshi Yasuda MD, PhD, FJCC","doi":"10.1016/j.jjcc.2025.04.003","DOIUrl":"10.1016/j.jjcc.2025.04.003","url":null,"abstract":"<div><h3>Background</h3><div>Pulmonary artery compliance (PAC), which could be estimated with gas exchange pulmonary arterial capacitance (GXcap), reflects the elasticity of the pulmonary vessels, and it is known that PAC is changed by pulmonary perfusion. GXcap could be measured using ventilatory gas analysis and is calculated using O<sub>2</sub> pulse × peak end-tidal CO<sub>2</sub> pressure. Moreover, it is known that pulmonary perfusion by postural changes is different between chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH). However, it was unclear whether GXcap could estimate PAC in CTEPH and PAH. Furthermore, it was unclear that change in GXcap with postural change (ΔGXcap) [Δ (Sitting - Supine)] was different between CTEPH and PAH.</div></div><div><h3>Methods</h3><div>Patients with suspected pulmonary hypertension who underwent right heart catheterization (RHC) from May 2022 to February 2023 in our institution were prospectively enrolled. Ventilatory gas analysis was performed before RHC in both the supine and sitting positions and calculated. Moreover, PAC was calculated with RHC. The diagnosis of PAH and CTEPH was based on the European Society of Cardiology/European Respiratory Society 2022 guidelines.</div></div><div><h3>Results</h3><div>Forty patients (CTEPH, <em>n</em> = 18; PAH, <em>n</em> = 22) were enrolled in this study. GXcap was positively related to PAC in these patients (<em>R</em> = 0.62, <em>p</em> < 0.001). Furthermore, PAC was significantly lower in CTEPH patients compared to PAH patients (median 1.63 mL/mmHg vs 2.05 mL/mmHg, <em>p</em> = 0.013). Moreover, GXcap was increased in CTEPH patients with postural change, while GXcap was decreased in PAH patients with postural change. Thus, ΔGXcap was significantly higher in CTEPH patients compared to PAH patients (median 5.8 mL × mmHg vs −2.6 mL × mmHg, <em>p</em> = 0.005).</div></div><div><h3>Conclusions</h3><div>It was suggested that PAC could be moderately estimated using GXcap in PAH and CTEPH patients. Moreover, it was suggested that ΔGXcap was higher in CTEPH patients compared with PAH patients.</div></div>","PeriodicalId":15223,"journal":{"name":"Journal of cardiology","volume":"86 1","pages":"Pages 97-99"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144011540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}