Journal of cardiology最新文献

{"title":"Impact of dementia and its progression on mortality in heart failure with preserved ejection fraction - Insight from the KUNIUMI Registry Chronic Cohort.","authors":"Yoshiro Kubota, Hidekazu Tanaka, Wataru Fujimoto, Haruna Yokota, Chihiro Fujii, Hiroshi Tsunamoto, Jun-Ichi Noiri, Koji Kuroda, Soichiro Yamashita, Junichi Imanishi, Masamichi Iwasaki, Takafumi Todoroki, Masanori Okuda, Akihide Konishi, Masakazu Shinohara, Manabu Nagao, Ryuji Toh, Kunihiro Nishimura, Hiromasa Otake","doi":"10.1016/j.jjcc.2026.10.003","DOIUrl":"10.1016/j.jjcc.2026.10.003","url":null,"abstract":"<p><strong>Background: </strong>Heart failure (HF) with preserved ejection fraction (HFpEF) is highly prevalent among older adults, while dementia is also an age-related condition characterized by cognitive decline, behavioral changes, and functional impairment. Although cognitive dysfunction is associated with worse outcomes in general HF populations, the specific prognostic implications of dementia and its progression in HFpEF remain unclear. This study aimed to investigate these associations in a real-world elderly HFpEF cohort.</p><p><strong>Methods: </strong>This prospective study included 965 patients with HFpEF without a history of stroke, drawn from 1646 consecutive HF patients in the KUNIUMI Registry Chronic Cohort, a population-based registry in Japan. Dementia was defined as an ABC Dementia Scale (ABC-DS) score < 100, and dementia progression as a ≥ 14-point decline in ABC-DS over 1-year. The primary endpoint was all-cause death, and the secondary endpoint was cardiovascular death or HF hospitalization over a mean follow-up of 2.0 ± 0.1-years.</p><p><strong>Results: </strong>Patients with dementia had significantly higher rates of all-cause death and cardiovascular death or HF hospitalization than those without dementia. These findings remained consistent after adjustment for baseline characteristics using propensity score matching. Furthermore, patients with dementia progression at 1-year had significantly higher all-cause death and cardiovascular death or HF hospitalization than those without progression. In multivariable Cox regression analysis, dementia progression was associated with all-cause death.</p><p><strong>Conclusions: </strong>Dementia, especially its progression, was associated with worse prognosis in HFpEF. These findings highlight the importance of longitudinal cognitive assessment to improve risk stratification and guide management strategies.</p>","PeriodicalId":15223,"journal":{"name":"Journal of cardiology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149127576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nationwide survey of prehospital 12-lead electrocardiogram recording and transmission in Japan: Equipment availability is no longer the major barrier.","authors":"Ken Saito, Yoshio Tahara, Migaku Kikuchi, Yoshio Kobayashi, Tetsuya Matoba, Tomoko Ishizu, Kunihiro Nishimura, Koichi Arimura, Koji Iihara, Teruo Noguchi","doi":"10.1016/j.jjcc.2026.10.001","DOIUrl":"10.1016/j.jjcc.2026.10.001","url":null,"abstract":"<p><strong>Background: </strong>Prehospital 12-lead electrocardiogram (ECG) improves survival in patients with ST-segment elevation myocardial infarction (STEMI). However, the current status of prehospital 12-lead ECG recording and transmission by emergency medical services (EMS) in Japan has not been investigated.</p><p><strong>Methods: </strong>A questionnaire survey on 12-lead ECG recording and transmission was conducted in collaboration with the Fire and Disaster Management Agency of the Ministry of Internal Affairs and Communications, targeting all 723 fire departments in Japan in 2023. Official data released by each fire department were also evaluated.</p><p><strong>Results: </strong>Of 588 responding fire departments (81.3%), 545 (92.7%) had at least partial access to 12-lead ECG recording equipment, whereas only 57 (9.7%) routinely utilized both recording and transmission. Multivariable logistic regression analysis indicated that routine 12-lead ECG recording [odds ratio (OR) 2.88, 95% confidence interval (CI) 1.70-4.87; p < 0.001], the presence of acute coronary syndrome or chest pain protocols (OR 2.89, 95% CI 1.86-4.48; p < 0.001), the presence of 12‑lead ECG recording equipment in all ambulances (OR 0.54, 95% CI 0.36-0.81, p = 0.003), and time from emergency call to arrival at the scene (OR 1.15, 95% CI 1.01-1.31, p = 0.028) were significant factors for the introduction of 12‑lead ECG transmission systems. When comparing responding facilities in regions with a single percutaneous coronary intervention (PCI)-capable hospital within the medical control council (46 facilities) and those with ≥2 PCI-capable hospitals (405 facilities), the 12‑lead ECG transmission system introduction rate was significantly higher in single PCI-capable hospitals than in ≥2 PCI-capable hospitals (46% vs. 30%, respectively; p = 0.027).</p><p><strong>Conclusions: </strong>Prehospital 12‑lead ECG recording equipment is widely available in Japan, but 12‑lead ECG transmission systems remain insufficiently implemented. The principal challenge is no longer equipment availability but establishing effective EMS-hospital communication pathways within regional STEMI networks.</p>","PeriodicalId":15223,"journal":{"name":"Journal of cardiology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149127543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simplified cardiac auscultation for the detection of valvular heart disease.","authors":"Hiroto Hayashi, Tatsuya Kawasaki, Hirofumi Kawamata, Sakiko Honda, Kuniyasu Kobayashi, Michiyo Yamano, Satoaki Matoba","doi":"10.1016/j.jjcc.2026.10.002","DOIUrl":"10.1016/j.jjcc.2026.10.002","url":null,"abstract":"","PeriodicalId":15223,"journal":{"name":"Journal of cardiology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149127538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on “Beta-blocker therapy for acute myocardial infarction with preserved ejection fraction: A meta-analysis from randomized controlled trials”","authors":"Shaoxun Wen MD,&nbsp;Ming Ouyang MD","doi":"10.1016/j.jjcc.2026.04.001","DOIUrl":"10.1016/j.jjcc.2026.04.001","url":null,"abstract":"","PeriodicalId":15223,"journal":{"name":"Journal of cardiology","volume":"88 4","pages":"Pages 335-336"},"PeriodicalIF":3.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147673754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on “Biomarker-based pre-heart failure screening in a middle-aged rural population”","authors":"Areeba Shabih","doi":"10.1016/j.jjcc.2026.03.013","DOIUrl":"10.1016/j.jjcc.2026.03.013","url":null,"abstract":"","PeriodicalId":15223,"journal":{"name":"Journal of cardiology","volume":"88 4","pages":"Page 334"},"PeriodicalIF":3.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147618724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter pulmonary valve implantation in patients with repaired tetralogy of Fallot: International evidence and the current status in Japan","authors":"Tomohito Kogure MD, PhD,&nbsp;Kei Inai MD, PhD, FJCC,&nbsp;Junichi Yamaguchi MD, PhD, FJCC","doi":"10.1016/j.jjcc.2026.01.013","DOIUrl":"10.1016/j.jjcc.2026.01.013","url":null,"abstract":"<div><div>In repaired tetralogy of Fallot (TOF), chronic pulmonary regurgitation drives right ventricular (RV) dilation, ventricular arrhythmias, and heart failure. Surgical pulmonary valve replacement improves outcomes but requires redo sternotomy. Transcatheter pulmonary valve implantation (TPVI) has emerged as a less invasive alternative. This review summarizes contemporary evidence and the Japanese context for TPVI. International registries report high procedural success and favorable mid-term outcomes with both balloon-expandable and self-expanding platforms. In Japan, two platforms are approved—SAPIEN 3 transcatheter heart valve (THV) (Edwards Lifesciences, Irvine, CA, USA) and Harmony transcatheter pulmonary valve (TPV) (Medtronic Inc., Minneapolis, MN, USA)—reflecting distinct anatomic targets. SAPIEN 3 THV is indicated for degenerated conduits or surgical bioprostheses in high-risk candidates, whereas Harmony TPV targets native, often dilated RV outflow tracts mainly after transannular patch repair. Although indications remain relatively restricted in Japan, early outcomes are expected to be favorable as experience grows. Key unresolved issues include long-term valve durability, post-TPVI antithrombotic strategy, arrhythmia surveillance, coronary compression risk, and timely referral before irreversible RV remodeling.</div><div>Overall, TPVI has transformed the management of pulmonary valve dysfunction after TOF repair and is increasingly recognized as first-line therapy in appropriate anatomies. In Japan, accumulating TPVI experience—combined with optimized patient selection and refinements in treatment strategy—is expected to further improve procedural safety and clinical outcomes. National registries and high-quality domestic studies are needed to guide indications, optimize lifetime strategies, and extend the benefits of TPVI.</div></div>","PeriodicalId":15223,"journal":{"name":"Journal of cardiology","volume":"88 4","pages":"Pages 237-243"},"PeriodicalIF":3.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146131355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety of same-day discharge after mitral transcatheter edge-to-edge repair","authors":"Atsuyuki Watanabe MD,&nbsp;Yuriko Hiruma MD,&nbsp;Yoshihisa Miyamoto MD, PhD,&nbsp;Hiroki A. Ueyama MD,&nbsp;Tadao Aikawa MD, PhD,&nbsp;Dhaval Kolte MD, PhD,&nbsp;Tsuyoshi Kaneko MD,&nbsp;Roger Laham MD,&nbsp;Toshiki Kuno MD, PhD,&nbsp;Yusuke Tsugawa MD, MPH, PhD","doi":"10.1016/j.jjcc.2026.05.006","DOIUrl":"10.1016/j.jjcc.2026.05.006","url":null,"abstract":"<div><h3>Background</h3><div>The safety of same-day discharge following mitral transcatheter edge-to-edge repair (M-TEER) in a nationwide setting remains unclear.</div></div><div><h3>Methods</h3><div>Using the administrative databases on Medicare fee-for-service beneficiaries, we identified patients aged 65–99 years undergoing elective M-TEER from 2016 to 2021 and who were discharged home on the same day or the next day after the procedure. We applied a linear probability model to examine the relationship between same-day discharge and patient outcomes, adjusting for patient demographics, underlying comorbidities, and hospital fixed effects (effectively comparing outcomes within the same hospital). The primary outcome was the composite of 30-day mortality and heart failure (HF) readmission.</div></div><div><h3>Results</h3><div>Of the total of 12,048 patients, 137 (1.1%) patients were discharged on the same day as the procedure. We did not find a statistically significant difference in the risk of the primary outcome [same-day discharge versus next-day discharge; adjusted risk difference (aRD), −1.0% points (pp); 95% confidence interval (CI), −2.8 to +0.8]. Similarly, we did not find significant differences between the two groups in 30-day mortality (aRD, −0.6 pp.; 95% CI, −2.0 to +0.9) and HF readmission (aRD, −0.5 pp.; 95% CI, −1.6 to +0.6).</div></div><div><h3>Conclusions</h3><div>In this study, we did not find evidence that the risk of 30-day mortality and HF readmission differed between same-day discharge and next-day discharge following M-TEER. Further investigations are needed to clarify who warrants prolonged observation after the procedures.</div></div>","PeriodicalId":15223,"journal":{"name":"Journal of cardiology","volume":"88 4","pages":"Pages 331-332"},"PeriodicalIF":3.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147987678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early-phase heart rate after ECPR: Prognostic signal, physiologic mediator, or therapeutic target?","authors":"Jiali Chen PhD,&nbsp;Guangzhi Ying PhD","doi":"10.1016/j.jjcc.2026.03.008","DOIUrl":"10.1016/j.jjcc.2026.03.008","url":null,"abstract":"","PeriodicalId":15223,"journal":{"name":"Journal of cardiology","volume":"88 4","pages":"Page 333"},"PeriodicalIF":3.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147529289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Triglyceride deposit cardiomyovasculopathy: A new class of cardiovascular disease","authors":"Tatsuya Mori MD,&nbsp;Ken-ichi Hirano MD, PhD,&nbsp;Hideyuki Miyauchi MD, PhD,&nbsp;Yoshihiko Ikeda MD, PhD,&nbsp;Masahiro Higashi MD, PhD,&nbsp;Yusuke Nakano MD, PhD,&nbsp;Takahiro Kanda MD,&nbsp;Yasuyuki Nagasawa MD, PhD,&nbsp;Tohru Inaba MD, PhD,&nbsp;Takahiro Okumura MD, PhD, FJCC,&nbsp;Nobuhiro Zaima PhD,&nbsp;Kunihisa Kobayashi MD, PhD,&nbsp;Naoya Matsumoto MD, PhD, FJCC,&nbsp;Tomomi Yamada PhD,&nbsp;Tetsuya Amano MD, PhD, FJCC,&nbsp;Shinichiro Fujimoto MD, PhD, FJCC,&nbsp;the Japan TGCV study group","doi":"10.1016/j.jjcc.2026.04.003","DOIUrl":"10.1016/j.jjcc.2026.04.003","url":null,"abstract":"<div><div>Triglyceride (TG) deposit cardiomyovasculopathy (TGCV) was first identified in Japanese patients with homozygous mutations in <em>PNPLA2</em> encoding adipose triglyceride lipase. TGs and fatty acids released by lipolytic action are major energy substrates in a normal heart. In TGCV, the defective intracellular lipolysis of long-chain TGs causes cellular steatosis and energy failure mainly in cardiomyocytes and vascular smooth muscle cells. One of the major characteristics is diffuse narrowing TG-deposited coronary atherosclerosis which is distinct from classic cholesterol-induced focal lesions. TGCV comprises primary and idiopathic subtypes with and without homozygous <em>PNPLA2</em> mutations, respectively. Genetic causes or backgrounds of idiopathic TGCV (I-TGCV) remain undetermined. We established the diagnostic criteria without requirement of genetic tests, including the reduced washout rate (&lt;10%) of iodine-123-β-methyl-<em>p</em>-iodophenyl-pentadecanoic acid in myocardial single-photon emission computed tomography, which reflects defective lipolysis, as an essential item. Serum TG level and body mass index are irrelevant to the diagnosis. As of October 2024, 15 primary TGCV (P-TGCV) and 976 I-TGCV cases were diagnosed across all Japanese prefectures. The cardiac symptoms of P-TGCV and I-TGCV occurred in patients aged in their 30s and 50s, respectively. The patients exhibited heart failure (HF), diffuse coronary artery disease including vasospastic angina, and ventricular arrhythmia. The prognosis was very severe in patients with P-TGCV manifesting HF with reduced ejection fraction unless receiving cardiac transplantation. In I-TGCV, the 5-year-overall and cardiovascular event-free survival rates were 71.8% and 54.0%, respectively, with standard remedies. Tricaprin/trisdecanoin, a medium-chain TG that facilitates myocardial lipolysis, is being developed as a first-in-class orphan drug for TGCV. TGCV is a novel class of adult-onset cardiovascular disease caused by the defective lipolysis of long-chain TGs. Many patients with TGCV exhibiting high cardiovascular risk remain undiagnosed; thus, increased awareness of this emerging disease is required among cardiologists of all subspecialties.</div></div>","PeriodicalId":15223,"journal":{"name":"Journal of cardiology","volume":"88 4","pages":"Pages 255-267"},"PeriodicalIF":3.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of severely calcified lesions -Intravascular imaging-guided percutaneous coronary intervention-","authors":"Hiroyuki Jinnouchi MD,&nbsp;Kenichi Sakakura MD,&nbsp;Yusuke Watanabe MD,&nbsp;Takunori Tsukui MD,&nbsp;Masaru Seguchi MD,&nbsp;Shun Ishibashi MD,&nbsp;Masashi Hatori MD,&nbsp;Taku Kasahara MD,&nbsp;Kei Yamamoto MD,&nbsp;Yousuke Taniguchi MD,&nbsp;Hideo Fujita MD, FJCC","doi":"10.1016/j.jjcc.2026.04.005","DOIUrl":"10.1016/j.jjcc.2026.04.005","url":null,"abstract":"&lt;div&gt;&lt;ul&gt;&lt;li&gt;&lt;span&gt;•&lt;/span&gt;&lt;span&gt;&lt;div&gt;Intravascular imaging enables detailed assessment of coronary calcium morphology.&lt;/div&gt;&lt;/span&gt;&lt;/li&gt;&lt;li&gt;&lt;span&gt;•&lt;/span&gt;&lt;span&gt;&lt;div&gt;Calcium characteristics strongly influence lesion preparation and luminal gain.&lt;/div&gt;&lt;/span&gt;&lt;/li&gt;&lt;li&gt;&lt;span&gt;•&lt;/span&gt;&lt;span&gt;&lt;div&gt;Distinguishing sheet calcification from calcified nodules informs device choice.&lt;/div&gt;&lt;/span&gt;&lt;/li&gt;&lt;li&gt;&lt;span&gt;•&lt;/span&gt;&lt;span&gt;&lt;div&gt;Effects of balloon, RA, OA, and IVL should be assessed based on IVI findings.&lt;/div&gt;&lt;/span&gt;&lt;/li&gt;&lt;li&gt;&lt;span&gt;•&lt;/span&gt;&lt;span&gt;&lt;div&gt;Imaging-guided PCI may improve safety and outcomes in severely calcified lesions.&lt;/div&gt;&lt;/span&gt;&lt;/li&gt;&lt;/ul&gt;&lt;/div&gt;&lt;div&gt;&lt;div&gt;Percutaneous coronary intervention (PCI) for severely calcified coronary lesions remains challenging, as extensive calcification frequently hampers adequate lesion preparation and optimal stent expansion, thereby increasing the risk of procedural complications and adverse clinical outcomes. The management of these complex lesions continues to require careful procedural planning. Intravascular imaging (IVI), including intravascular ultrasound and optical coherence tomography/optical frequency domain imaging, provides detailed insights into coronary calcium morphology. IVI has become an important tool in contemporary PCI. IVI allows comprehensive evaluation of calcium characteristics such as arc, longitudinal length, thickness, depth, and surface morphology. These findings are closely related to lesion compliance and subsequent stent expansion. The information from IVI facilitates appropriate selection and optimization of calcium modification strategies, including conventional balloons, atherectomy devices, and intravascular lithotripsy. Furthermore, IVI enables assessment of procedural effectiveness by confirming plaque modification, calcium fracture, and stent expansion, while also identifying imaging features associated with an increased risk of vessel injury, dissection, or slow flow. However, each imaging modality has inherent limitations, and careful interpretation of imaging findings is essential, particularly in severely calcified lesions. In this review, we summarize current concepts of IVI-based assessment of coronary calcification and discuss practical considerations for device selection and lesion preparation in severely calcified lesions. Integrating intravascular imaging into PCI may contribute to more tailored treatment strategies and improved clinical outcomes in patients with severely calcified coronary artery disease.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;Percutaneous coronary intervention (PCI) for severely calcified coronary lesions remains challenging, as extensive calcification frequently hampers adequate lesion preparation and optimal stent expansion, thereby increasing the risk of procedural complications and adverse clinical outcomes. The management of these complex lesions continues to require careful procedural planning. Intravascular imaging (IVI), including intravascular ultrasound and optic","PeriodicalId":15223,"journal":{"name":"Journal of cardiology","volume":"88 4","pages":"Pages 268-279"},"PeriodicalIF":3.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147698441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}