Noemi Bruno, Marco Russo, Amedeo Pergolini, Antonio Giovanni Cammardella, Francesco Musumeci, Federico Ranocchi
{"title":"Accuracy of Lone Three-dimensional Transthoracic Echocardiography in Tricuspid Valve Function and Geometry Assessment: Implication for Preoperative Evaluation of Transcatheter Tricuspid Valve Therapies.","authors":"Noemi Bruno, Marco Russo, Amedeo Pergolini, Antonio Giovanni Cammardella, Francesco Musumeci, Federico Ranocchi","doi":"10.4103/jcecho.jcecho_53_24","DOIUrl":"10.4103/jcecho.jcecho_53_24","url":null,"abstract":"<p><strong>Introduction: </strong>Tricuspid regurgitation (TR) is associated with high rate and poor prognosis in patient undertreated. In recent years, transcatheter tricuspid valve interventions (TTVI) appears like a valuable option in high risk surgical candidates in presence of suitable anatomy. Screening phase with transthoracic, thansoesophageal echocardiography, and cardiac computed tomography (CT) are necessary select patients.</p><p><strong>Purpose: </strong>The aim of the study is to compare different imaging modalities as three-dimensional (3D) transthoracic echocardiography (TTE), transesophageal echocardiography (TOE) and ECG-gated cardiac CT for the definition of tricuspid valve (TV) function and geometry assessment.</p><p><strong>Materials and methods: </strong>Twenty-one (age 79 ± 7 years, female 72%) patients under screening for transcatheter treatment of TR were prospectively enrolled in the study and underwent TTE, TOE, and cardiac CT. All measurements were performed in double blind by three different operators and compared.</p><p><strong>Results: </strong>In the comparison between 2D/3D TTE and 2D/3D TOE, no statistically significant differences were found regarding the evaluation of the valve anatomy, the site of regurgitation, and the underlying mechanism (TTE vs. TOE: 3D septo-lateral diam 45.8 ± 4,92 vs. 45.87 ± 4,98 mm, <i>P</i> = 0.87; 3D antero-posterior diam 43.5 ± 4,58 vs. 43.5 ± 4,53 mm, <i>P</i> = 0.59; Circularity index 0,75 ± 0,08 vs. 0,76 ± 0,08, <i>P</i> = 0.98). When comparing 3D TTE and cardiac CT, no differences were recorded in terms of TV area 17.58 ± 3 versus 17.71 ± 4,3 cm<sup>2</sup>, <i>P</i> = 0.1; perimeter 14.89 ± 1,6 versus 14.29 ± 1 cm, <i>P</i> = 0.5 and diameters. Similarly, in the study of right ventricular dimensions, obtained through 3D volumetric reconstruction, TTE was not statistically different to Cardiac CT.</p><p><strong>Conclusions: </strong>The present series shows how a lone 3D TTE has a good reliability in the definition of TV function, leaflet characteristics, and geometry when compared with second level imaging modalities and may be safely used to select optimal candidates for complex TTVI.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"34 4","pages":"186-195"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11784727/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giovanni Di Salvo, Saleem Muhammad, Domenico Galzerano, Al Jufan Mansour
{"title":"Multimodality Imaging Approach in Infective Endocarditis: When Less is More.","authors":"Giovanni Di Salvo, Saleem Muhammad, Domenico Galzerano, Al Jufan Mansour","doi":"10.4103/jcecho.jcecho_50_24","DOIUrl":"10.4103/jcecho.jcecho_50_24","url":null,"abstract":"<p><p>The latest ESC guidelines advocate for a multimodality imaging approach in diagnosing infective endocarditis, incorporating echocardiography, computed tomography (CT), magnetic resonance imaging, positron emission tomography/CT, and single-photon emission CT/CT to enhance diagnostic accuracy. This case study examines the limitations of this approach in a patient with suspected prosthetic valve endocarditis, suggesting that while multimodality imaging is valuable, a clinically oriented strategy may be more effective in certain situations.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"34 4","pages":"219-221"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11784728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara Hana Weisz, Chiara Sordelli, Nunzia Fele, Angela Guarino, Raffaele Verde, Giulio Zucchelli, Corrado Severino, Vittorio Attanasio, Stefano De Vivo, Carlo Tascini, Sergio Severino
{"title":"One-year Impact of Clinical and Echocardiographic Parameters in Cardiac Implantable Electronic Device Infection after Transvenous Extraction.","authors":"Sara Hana Weisz, Chiara Sordelli, Nunzia Fele, Angela Guarino, Raffaele Verde, Giulio Zucchelli, Corrado Severino, Vittorio Attanasio, Stefano De Vivo, Carlo Tascini, Sergio Severino","doi":"10.4103/jcecho.jcecho_55_24","DOIUrl":"10.4103/jcecho.jcecho_55_24","url":null,"abstract":"<p><strong>Introduction: </strong>Cardiac implantable electronic device infection (CIEDi) represents a serious complication with a poor prognosis. Many studies have underlined the importance of comorbidities on prognosis, but less is known about the impact of echocardiographic parameters. The aim of our study was to evaluate the clinical and echocardiographic characteristics of patients hospitalized for CIEDi submitted to transvenous extraction and their impact on 1-year follow-up.</p><p><strong>Materials and methods: </strong>This is a retrospective cohort study that evaluated patients hospitalized for CIEDi in 2019 in two high-volume centers (Cotugno Hospital of Napoli and University Hospital of Pisa).</p><p><strong>Results: </strong>Sixty-eight patients (72 ± 12 years, 24% females) were included. Isolated pocket infection was present in 30 patients (44%), whereas systemic infection in 38 (56%). In 24 patients (35%), it was possible to identify responsible germ, with a higher prevalence of <i>Staphylococcus epidermidis</i> (24%) and <i>Staphylococcus aureus</i> (16%). The mean ejection fraction (EF) was 45 ± 14%, 44% of patients had one vegetation (11.0 ± 8.0 mm), and 19% had multiple. Transthoracic echocardiography (TTE) failed to identify vegetation in 16 patients, whereas transesophageal echocardiography (TEE) was diagnostic. All patients underwent transvenous extraction of infected devices. After the procedure, echocardiographic ghosts were found in six patients (9%). At 1-year follow-up, all-cause mortality was 16%, mortality for cardiovascular cause was 12%, and no reinfection was recorded. Patients with EF ≤40% showed a significantly higher incidence of all-cause mortality (32% vs. 5%, <i>P</i> = 0.003) and mortality for cardiovascular causes (25% vs. 3%, <i>P</i> = 0.005). At adjusted Cox regression model, reduced EF ≤40% (adjusted hazard ratio [AdjHR] = 9.887, confidence interval [CI] =1.782-54.863; <i>P</i> = 0.009) and diabetes (AdjHR = 5.687, CI = 1.243-26.011; <i>P</i> = 0.025) were strong independent predictors of all-cause mortality. Moreover, reduced EF ≤40% (AdjHR = 17.382, CI = 1.379-219.037; <i>P</i> = 0.027), the presence of ghost (AdjHR = 14.584, CI = 1.465-145.197; <i>P</i> = 0.022), and diabetes (AdjHR = 11.334, CI = 1.506-85.315; <i>P</i> = 0.018) were strong independent predictors of mortality for cardiovascular cause.</p><p><strong>Conclusions: </strong>Echocardiography (TTE and TEE) is a fundamental tool for the diagnosis and follow-up of CIEDi. In our population, diabetes mellitus and echocardiographic-derived parameters as reduced EF ≤40% and the presence of ghosts were strongly associated with 1-year mortality.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"34 4","pages":"196-202"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11784730/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mattia Alberti, Alessandro Marcucci, Filippo Biondi, Simona Chiusolo, Gabriele Masini, Lorenzo Faggioni, Dania Cioni, Doralisa Morrone, Raffaele De Caterina, Emanuele Neri, Giovanni Donato Aquaro
{"title":"Pancreatitis-associated Myocarditis: Systematic Review and Meta-analysis of a Deadly Duo.","authors":"Mattia Alberti, Alessandro Marcucci, Filippo Biondi, Simona Chiusolo, Gabriele Masini, Lorenzo Faggioni, Dania Cioni, Doralisa Morrone, Raffaele De Caterina, Emanuele Neri, Giovanni Donato Aquaro","doi":"10.4103/jcecho.jcecho_59_24","DOIUrl":"10.4103/jcecho.jcecho_59_24","url":null,"abstract":"<p><p>Myocardial injury is a recognized complication of acute pancreatitis, whereas myocarditis has only been occasionally reported and has not been systematically evaluated. We systematically reviewed PubMed literature published up to January 2024 for studies including both \"myocarditis\" and \"pancreatitis\" as keywords. Relevant data regarding patient characteristics and outcomes were collected and analyzed. A total of 31 patients from 31 independent studies were included. The etiology of pancreatitis was viral in 52%, bacterial in 20%, toxic in 16%, autoimmune in 9%, and idiopathic in 3%. 23% of patients were immunocompromised. Median high sensitivity-cardiac troponin T was 342 (IQR 73-890) ng/L and N-terminus-pro-brain natriuretic peptide was 11053 (IQR 1397-26150) pg/mL. The average left ventricular ejection fraction was 33±13%. Fulminant myocarditis, presenting with cardiogenic shock and/or malignant ventricular arrhythmias occurred in 48% of patients, more frequently in men than in women (<i>P</i>=0.026). Severe myocarditis occurred in 42% of edematous and 60% of necrotizing pancreatitis (<i>P</i>=0.56). No association was found between the severity of myocarditis and plasma levels of amylase (<i>P</i>=0.98) and lipase (<i>P</i>=0.83). The relative frequency of severe myocarditis was 80% in pancreatitis due to Leptospirosis, and 40% in pancreatitis due to viral infections. The mortality rate was 22%: 13% died during hospitalization and 9% after. Myocarditis is a potentially lethal complication of pancreatitis and is more frequently associated with viral etiology in immunocompromised individuals. Based on such findings, cardiac troponin measurements and an electrocardiogram are advisable to exclude myocardial involvement in selected patients. Confirmatory diagnosis and prognostic assessments should be based on cardiac magnetic resonance imaging.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"34 4","pages":"160-169"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11784726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muataz F Hussein, Wisam J Mohammad, Samar Omran Essa
{"title":"Echocardiographic Evaluation of Central Venous Pressure Using Inferior Vena Cava Characteristics: An Estimate Guide for Right Atrial Pressure in Intensive Care Unit.","authors":"Muataz F Hussein, Wisam J Mohammad, Samar Omran Essa","doi":"10.4103/jcecho.jcecho_2_24","DOIUrl":"10.4103/jcecho.jcecho_2_24","url":null,"abstract":"<p><strong>Background: </strong>Central venous pressure (CVP) is a good approximation of right atrial pressure (RAP), which in turn is a major determinant of right ventricular filling. The inferior vena cava (IVC) is a compliant vessel whose size and shape vary with changes in CVP. IVC diameter and Collapsibility Index (CI) assessed by echocardiography are used as indirect indicators for the estimation of RAP.</p><p><strong>Aim of the study: </strong>To evaluate the correlation between IVC echocardiographic characteristics and CVP and RAP and the value of assessment of IVC as a guide for the status of the right side of the heart.</p><p><strong>Patients and methods: </strong>A total of sixty patients (male and female) above 18 years of age, who were admitted in the intensive care unit, were enrolled in this single-center, descriptive cross-sectional study. Echocardiographic assessment of IVC hemodynamics (IVC expiratory [IVCe] and inspiratory [IVCi] diameters and IVC-CI) were carried out. In addition to standard echocardiographic examination, right heart function measurements (Tricuspid annular plane systolic excursion [TAPSE] and right atrial [RA] area) in spontaneously and mechanically ventilated patients were done.</p><p><strong>Results: </strong>The average age of the patients was 62 years (18-80 years). Overall, 45% (<i>n</i> = 27) were male and 55% (<i>n</i> = 33) were female. The breathing modality was mechanical ventilation in 27 (45%) patients and spontaneous breathing in 33 (55%) patients. Both IVCe and IVCi diameters showed a strong negative correlation with CI, (<i>r</i> = -0.920 for IVCe and <i>r</i> = -0.964 for IVCi) (<i>P</i> < 0.001). There was a positive correlation between TAPSE and IVC-CI (<i>r</i> = 0.857, <i>P</i> < 0.001). IVC-CI in mechanically ventilated patients was (mean ± standard deviation [SD], 40.11 ± 1.782) compared to spontaneous breathing (mean ± SD, 48.91 ± 1.811) (<i>P</i> < 0.001).</p><p><strong>Conclusions: </strong>There is a linear relationship of IVC-CI with TAPSE but an inverse relation with RA area. Evaluation of IVC diameter and its CI is an easy and noninvasive method to estimate CVP and RAP and so evaluate right heart performance of critically ill patients. Its use is more helpful in patients who are spontaneously breathing than those who are mechanically ventilated.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"34 4","pages":"206-213"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11784733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Double Orifice Mitral Valve: Two Patients with Contrasting Presentations.","authors":"Jaideep Dey, Shailendra Bhadoriya, Vijay Singh Chauhan, Arif Mustaqueem, Sameer Shrivastava","doi":"10.4103/jcecho.jcecho_54_24","DOIUrl":"10.4103/jcecho.jcecho_54_24","url":null,"abstract":"<p><p>Double orifice mitral valve, despite being an extremely rare entity, may be encountered on routine echocardiographic studies in adults. The varied morphology of the valve may be complicated by coexisting anomalies of the subvalvular apparatus. We present the cases of two patients with this condition and associated papillary muscle anomalies. A thorough echocardiographic study with three-dimensional imaging was pivotal in making a final diagnosis.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"34 4","pages":"222-227"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11784732/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabriele Cordoni, Morena De Amicis, Maria Teresa Savo, Raffaella Motta
{"title":"Cardiac Computed Tomography Detected the Hidden Culprit of a Cryptogenic Stroke: A \"Cold\" Case.","authors":"Gabriele Cordoni, Morena De Amicis, Maria Teresa Savo, Raffaella Motta","doi":"10.4103/jcecho.jcecho_57_24","DOIUrl":"10.4103/jcecho.jcecho_57_24","url":null,"abstract":"<p><p>Around 25%-40% of ischemic strokes are cryptogenic, with no identifiable cause despite thorough evaluation. The mechanisms behind cryptogenic strokes are often embolic, frequently originating from occult cardiac sources. An unroofed coronary sinus (UCS), a rare congenital anomaly, involves a partial or complete absence of the coronary sinus roof, leading to a connection between the left atrium and the coronary sinus. This defect can be asymptomatic or present with symptoms such as paradoxical embolism due to shunting. We present the case of a 70-year-old male with prolonged chest pain and a history of neurological symptoms, who was later diagnosed with a UCS (types III and IV) through cardiac computed tomography (CCT). A cardiac bubble test confirmed a right-to-left shunt, which was not detected on transthoracic echocardiography. This case underscores the importance of considering advanced imaging techniques such as CCT in the diagnosis of cryptogenic stroke, as echocardiography may miss defects due to poor visualization of posterior cardiac structures.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"34 4","pages":"228-231"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11784734/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improving Outcomes in Peripartum Cardiomyopathy with Vericiguat: A Clinical Case.","authors":"Fulvio Cacciapuoti, Ciro Mauro, Valentina Capone, Fabio Marsico, Luca Gaetano Tarquinio, Federico Cacciapuoti","doi":"10.4103/jcecho.jcecho_48_24","DOIUrl":"10.4103/jcecho.jcecho_48_24","url":null,"abstract":"<p><p>Peripartum cardiomyopathy (PPCM) is a specific form of cardiomyopathy that manifests toward the end of pregnancy or within 5 months postpartum, characterized by a decrease in cardiac output due to impaired myocardial function. This condition has a multifactorial origin, influenced by genetic predispositions, inflammatory processes, autoimmunity, hormonal variations, and nutritional deficiencies. Prognosis varies among patients: while some recover completely within 6 months, others may develop chronic cardiac dysfunction requiring long-term treatment. Vericiguat, a soluble guanylate cyclase stimulator, has shown promising results in the treatment of heart failure with reduced ejection fraction. This drug works by enhancing the nitric oxide signaling pathway, promoting vasodilation, and improving myocardial function. Although the use of vericiguat in PPCM is not yet fully documented, its potential benefits suggest that it may represent a valid therapeutic option when standard therapies are insufficient for symptom control. We present the case of a 32-year-old woman with PPCM, initially undiagnosed, who developed severe symptoms of dyspnea, orthopnea, and peripheral edema postpartum. These symptoms were accompanied by a significant reduction in left ventricular ejection fraction. Following a suboptimal response to standard heart failure therapy, vericiguat was incorporated into her treatment regimen. In subsequent outpatient follow-ups, the patient's symptoms progressively improved, and left ventricular systolic function markedly increased. The patient became asymptomatic and was able to resume her normal daily activities. While this case suggests that vericiguat could be an effective adjunctive treatment for PPCM, it remains unclear whether these improvements were directly attributable to vericiguat or could have occurred with continued standard therapy alone. Further studies are needed to define the role of vericiguat in this condition.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"34 4","pages":"214-218"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11784736/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Valentina Barletta, Antonio Maria Canu, Matteo Parollo, Andrea Di Cori, Luca Segreti, Raffaele De Lucia, Maria Grazia Bongiorni, Giulio Zucchelli
{"title":"A Long Atrial Electromechanical Interval is Associated with Arrhythmic Recurrence after Catheter Ablation: How to Find What Has Been Lost.","authors":"Valentina Barletta, Antonio Maria Canu, Matteo Parollo, Andrea Di Cori, Luca Segreti, Raffaele De Lucia, Maria Grazia Bongiorni, Giulio Zucchelli","doi":"10.4103/jcecho.jcecho_35_24","DOIUrl":"https://doi.org/10.4103/jcecho.jcecho_35_24","url":null,"abstract":"<p><strong>Background: </strong>Atrial fibrillation (AF) results in electrical and structural remodeling of the atria, which extent is known to be associated with a higher AF recurrence rate after catheter ablation (CA). Recently, a novel echocardiographic parameter derived from tissue Doppler imaging (TDI) [PA-TDI] has been introduced to assess the total atrial activation time, as a noninvasive surrogate of fibrosis and remodeling. The aim of the study is to investigate the role of PA-TDI interval as a predictor of AF ablation efficacy.</p><p><strong>Methods: </strong>We retrospectively included patients with paroxysmal symptomatic drug-refractory AF referred to our institution for CA procedure, who presented sinus rhythm at admission. A complete transthoracic echocardiogram was performed before the ablation procedure, including the assessment of PA-TDI interval.</p><p><strong>Results: </strong>From January 2015 to April 2018, 128 patients (mean age: 61.86 ± 9.08 years, 68% male, body surface area: 1.97 ± 0.21 mq, body mass index: 26.98 ± 3.86 kg/mq, and ejection fraction: 59% ±6.06%) with symptomatic drug-refractory AF who received radiofrequency CA were enrolled. During the follow-up of 15.80 ± 6.7 months, 30 patients (23%) developed AF recurrence out of the blanking period. Compared with those without recurrence (group 1), patients with recurrence (group 2) had a larger left atrium (LA) size (Group 1 vs. Group 2: mean LA area: 22.2 ± 4.6 cmq vs. 25 ± 6.6 cmq, <i>P</i> = 0.015; mean indexed LA volume: 35 ± 10 mL/mq vs. 40 ± 12 mL/mq, <i>P</i> = 0.04) and longer PA-TDI interval (Group 1 vs. Group 2: 162 ± 33 ms vs. 133 ± 26 ms, <i>P</i> < 0.0001). A cutoff of PA-TDI > 150 ms identified patients with recurrence after ablation with a sensibility of 82% and specificity of 83% (area under the curve 0.879).</p><p><strong>Conclusions: </strong>The total activation time assessed by PA-TDI is an independent predictor of AF recurrence and can be used to predict the efficacy of transcatheter ablation.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"34 3","pages":"125-131"},"PeriodicalIF":0.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495311/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142501044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eleonora Lassandro, Maria Teresa Savo, Marika Martini, Serena Pinci
{"title":"Detection of Fibroadipose Tissue Infiltration with Cardiac Computed Tomography: A Case of Arrhythmogenic Cardiomyopathy.","authors":"Eleonora Lassandro, Maria Teresa Savo, Marika Martini, Serena Pinci","doi":"10.4103/jcecho.jcecho_33_24","DOIUrl":"https://doi.org/10.4103/jcecho.jcecho_33_24","url":null,"abstract":"<p><p>In the evaluation of cardiomyopathies, cardiac computed tomography (CCT) is predominantly used for assessing congenital or acquired coronary artery diseases as a potential etiology underlying the observed myocardial abnormalities. However, its utility is expected to expand. We present a case of an asymptomatic patient with claustrophobia who sought medical attention due to frequent ventricular beats. The resting electrocardiogram revealed repolarization abnormalities characterized by flattened T-waves in the lateral leads and low QRS voltages in the peripheral leads, whereas transthoracic echocardiography was normal. CCT accurately identified hypodense areas indicative of fibrofatty infiltration within the inferolateral and anterior walls of the left ventricle. Furthermore, late iodine contrast-phase imaging revealed subepicardial late enhancement striae in the same regions. These imaging findings were pivotal in establishing a diagnosis of left-dominant arrhythmogenic cardiomyopathy. This clinical vignette underscores the potential of CCT in tissue characterization, particularly when cardiac magnetic resonance imaging is contraindicated or unavailable.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"34 3","pages":"137-139"},"PeriodicalIF":0.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142516471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}