Journal of Cardiovascular Echography最新文献

{"title":"Deferred versus Immediate Stenting in ST-segment Elevation Myocardial Infarction Patients with High Thrombus Burden: A Randomized Clinical Trial Using Three-dimensional Speckle Tracking Echocardiography.","authors":"Ahmed Saeid Eldamanhory, Hesham Hafez Abdelkhalek Mosa, Mahmoud Elsaid Soliman, Mohamed Ibrahim Awadi, Hisham Samir Roshdy, Islam Elsayed Shehata","doi":"10.4103/jcecho.jcecho_130_25","DOIUrl":"10.4103/jcecho.jcecho_130_25","url":null,"abstract":"<p><strong>Objectives: </strong>The optimal timing of stent implantation in ST-segment elevation myocardial infarction (STEMI) with high thrombus burden remains uncertain. Immediate stenting carries a risk of distal embolization and no-reflow, whereas deferred stenting may facilitate improved microvascular recovery. This study compared angiographic and echocardiographic outcomes of immediate versus deferred stenting using three-dimensional speckle tracking echocardiography (3D-STE).</p><p><strong>Materials and methods: </strong>In this randomized clinical trial, 115 STEMI patients with high thrombus burden were allocated to immediate stenting (<i>n</i> = 60) or deferred stenting after dual antiplatelet therapy plus enoxaparin (<i>n</i> = 55). Primary endpoints were final thrombolysis in myocardial infarction (TIMI) flow, myocardial blush grade (MBG), and left ventricular ejection fraction (LVEF) by 3D-STE. Secondary endpoints included global strain parameters and major adverse cardiovascular events (MACE) at 6 months.</p><p><strong>Results: </strong>Deferred stenting achieved higher TIMI III flow (76.4% vs. 60.0%, <i>P</i> < 0.001) and MBG 3 (63.6% vs. 41.7%, <i>P</i> = 0.0025). Both groups showed improved LVEF at 6 months, with greater gains in the deferred group (EF change: 14.05% vs. 12.89%, <i>P</i> = 0.043). Favorable but nonsignificant trends were noted in global longitudinal, circumferential, and radial strain. MACE rates were similar between groups (34.5% vs. 41.7%, <i>P</i> = 0.45).</p><p><strong>Conclusions: </strong>Deferred stenting in STEMI patients with high thrombus burden enhanced angiographic reperfusion and improved recovery of left ventricular function without reducing short-term MACE. These findings suggest deferred stenting as a feasible strategy to optimize myocardial reperfusion, warranting larger, long-term trials to evaluate its prognostic impact.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"36 2","pages":"117-123"},"PeriodicalIF":1.1,"publicationDate":"2026-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13322605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148368329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Yeo's Index for Mitral Valve Assessment during Percutaneous Transvenous Mitral Commissurotomy.","authors":"Jamal Yusuf, Ankit Bansal, Dixit Goyal, Arima Nigam, Vimal Mehta, Ankur Gautam, Mohit D Gupta, Gaurav Sharma","doi":"10.4103/jcecho.jcecho_107_25","DOIUrl":"10.4103/jcecho.jcecho_107_25","url":null,"abstract":"<p><strong>Background: </strong>Rheumatic mitral stenosis (MS) severity assessment by planimetry, pressure half-time (PHT), and continuity equation (CE) has limitations. Yeo's index, the product of mitral leaflet separation index and dimensionless index, combining anatomic and hemodynamic severity, offers a promising alternative.</p><p><strong>Objective: </strong>The objective of this study was to evaluate the Yeo's index accuracy in MS before and after percutaneous transvenous mitral commissurotomy (PTMC) and its correlation with conventional methods and mitral valve area (MVA) by three-dimensional (3D) transesophageal echocardiography (TEE).</p><p><strong>Materials and methods: </strong>A prospective, single-center interventional study of 100 patients with severe symptomatic MS undergoing PTMC. Transthoracic echocardiography and 3D TEE were performed pre-PTMC and 48 h post-PTMC.</p><p><strong>Results: </strong>The mean age was 35.94 years, with 68% of females and 34% in atrial fibrillation (AF). The mean Yeo's index before PTMC was 0.16 ± 0.08 cm, and after PTMC, it increased to 0.31 ± 0.12 cm. Pre-PTMC, the Yeo's index showed moderate-to-strong positive correlations with MVA by PHT (<i>r</i> = 0.584), planimetry (<i>r</i> = 0.483), 3D TEE (<i>r</i> = 0.592), and CE (<i>r</i> = 0.665); <i>P</i> < 0.0001. Post-PTMC, correlations remained strong with CE (<i>r</i> = 0.665) and 3D TEE (<i>r</i> = 0.643); <i>P</i> < 0.0001. Receiver operating curve analysis confirmed its strong predictive value, with a pre-PTMC cutoff of < 0.147 cm identifying very severe MS (area under the curve [AUC]: 0.974; sensitivity: 94.74% and specificity: 100%) in non-AF and AF patients (AUC = 0.95; sensitivity: 90% and specificity: 100%). Severe MS was defined with a cutoff of 0.147 - 0.26 cm (AUC = 0.964 in non-AF and 0.95 in AF).</p><p><strong>Conclusion: </strong>The Yeo's index is a reliable, noninvasive tool for assessing MS severity both pre-and post-PTMC, demonstrating strong correlations and accuracy even in AF.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"36 2","pages":"148-155"},"PeriodicalIF":1.1,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13322590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148368520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aortic Artery Pulsatility Index (API) Estimated by Echocardiography and Prognosis in Patients with Decompensated Heart Failure.","authors":"Ahmed E Gaafar, Mohamed S Ahemed, Mohamed G Elbahnasawy","doi":"10.4103/jcecho.jcecho_81_25","DOIUrl":"10.4103/jcecho.jcecho_81_25","url":null,"abstract":"<p><strong>Aim of study: </strong>Role of noninvasive aortic artery pulsatility index (API) estimated by echocardiography to predict the prognosis in patients who hospitalized with decompensated heart failure (HF) during hospital course and for 3 months after discharge with comparing this prognosis with KCCQ score.</p><p><strong>Patients and methods: </strong>The study was occurred on 115 patients who hospitalized at Helwan University Badr Hospital with manifestations of decompensated heart failure (DHF) which is defined in patients whose left ventricular systolic function <40% and were stable on their medications then suddenly developed rapid deterioration in symptoms and signs of HF that need hospitalization. API is the ratio of (difference between systemic systolic pressure and systemic diastolic pressure) to pulmonary capillary wedge pressure which detected by echocardiographic equation as 1.9+ (E/é X1.24).</p><p><strong>Results: </strong>Patients with API values below cutoff value (1.45) had sensitivity 73% and specificity 98% (area under the curve = 0.908, <i>P</i> < 0.00) to predict poor prognosis and worse clinical outcome in patients with DHF during hospital stay and after hospital discharge for 3 months.</p><p><strong>Conclusion: </strong>Noninvasive API can predict the mortality and various clinical complications as cardiogenic shock, myocardial infarction, fatal arrhythmias, and stroke in patients with DHF during hospital course and HF rehospitalization, mortality after hospital discharge for 3 months.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"36 2","pages":"111-116"},"PeriodicalIF":1.1,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13322578/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148368356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidentally Detected Simultaneous Multiple Myxomas and an Atrial Septal Defect.","authors":"Armina Radmanesh, Sahar Asl-Fallah, Jamshid Bagheri, Mohammad-Ali Boroumand, Sajad Ahmadi-Renani, Ali Hosseinsabet","doi":"10.4103/jcecho.jcecho_103_25","DOIUrl":"10.4103/jcecho.jcecho_103_25","url":null,"abstract":"<p><p>Myxoma is a common primary benign cardiac tumor that typically occurs in middle age. It is usually single and frequently found in the left atrium, particularly attached to the interatrial septum. An atrial septal defect (ASD) is a congenital defect, and myxomas often involve the interatrial septum. Therefore, the coexistence of these two conditions, especially when myxomas are multiple, is rare. We present a middle-aged man with a secundum-type ASD and two myxomas located in the right atrium and left ventricle, which were discovered incidentally. This implies that, in patients with one or multiple myxomas, it is essential to consider the potential presence of an ASD when searching for myxomas in the cardiac chambers.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"36 2","pages":"182-185"},"PeriodicalIF":1.1,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13322592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148368384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Accuracy of Contrast-enhanced Transcranial Doppler for Patent Foramen Ovale Detection in Adults: Systematic Review and Meta-analysis.","authors":"Yunus Emre Yavuz, Sefa Tatar, Hakan Akilli, Yakup Alsancak, Abdullah İçli, Hasan Küçükkendirci","doi":"10.4103/jcecho.jcecho_128_25","DOIUrl":"10.4103/jcecho.jcecho_128_25","url":null,"abstract":"<p><p>Contrast-enhanced transcranial Doppler (c-TCD) is a promising noninvasive method for detecting patent foramen ovale (PFO) in adults, but its diagnostic accuracy compared to the gold standard transesophageal echocardiography (TEE) requires up-to-date evaluation. We conducted a systematic review and meta-analysis of studies from 2015 to 2025 assessing c-TCD for PFO detection in adults, following the PRISMA guidelines. A comprehensive search identified 37 relevant articles; of these, five primary studies met the inclusion criteria for quantitative analysis. Data on sensitivity, specificity, and othervdiagnostic performance metrics were extracted, and study quality was appraised using QUADAS-2. The included studies (mostly cryptogenic stroke patients) indicated that c-TCD had high sensitivity (~95%) and good specificity (~90%) for detecting PFO compared to TEE. In our meta-analysis, the summary sensitivity of c-TCD was 94.8% (95% confidence interval [CI]: 91%-98%) and the specificity was 89.7% (95% CI: 85%-94%). The pooled positive likelihood ratio was ~9, and the negative likelihood ratio was ~0.06. The diagnostic odds ratio was approximately 150, and the area under the curve of the summary receiver operating characteristic curve was approximately 0.97, reflecting excellent overall accuracy. Contrast TCD demonstrates robust diagnostic performance for PFO detection, approaching that of TEE. A negative result on c-TCD reduces the likelihood of clinically significant PFO in patients with stroke, whereas a positive c-TCD strongly suggests PFO and should prompt confirmatory TEE for anatomical details. These findings support the use of c-TCD as a first-line screening tool in the evaluation of cryptogenic stroke.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"36 2","pages":"89-100"},"PeriodicalIF":1.1,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13322588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148368267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-dimensional Evaluation of Atrioventricular Valve Geometry in the Fetal Heart: Establishing Reference Standards and Clinical Validation.","authors":"Tassyele Pamplona Nogueira, Gustavo Yanno Callado, Nathalie Jeanne Bravo-Valenzuela, Edward Araujo Júnior","doi":"10.4103/jcecho.jcecho_14_26","DOIUrl":"10.4103/jcecho.jcecho_14_26","url":null,"abstract":"<p><strong>Objective: </strong>To establish the reference values for the angle between the atrioventricular (AV) valve insertion levels in fetal hearts using three-dimensional ultrasound with Spatio-temporal Image Correlation (STIC) rendering and to validate these values in fetuses with confirmed congenital heart disease (CHD).</p><p><strong>Materials and methods: </strong>A retrospective cross-sectional study was conducted using 59 STIC volumes from structurally normal fetuses between 20 and 33 + 6 weeks of gestation. The AV valve insertion angle was measured in the rendering mode of four-chamber view. A polynomial regression model was used to generate a reference curve and percentile table. A validation cohort of 26 fetuses with CHD was analyzed, and angle distributions were compared with the normative percentiles.</p><p><strong>Results: </strong>The insertion angle remained stable throughout gestation. Reference percentiles (5^th, 10^th, 50^th, 90^th, and 95^th) were established by gestational week. Among fetuses with CHD, 46.2% had angles below the 5^th percentile and 57.7% above the 95^th percentile, with only 7.7% within the normal range. Specific CHD such as tetralogy of Fallot, transposition of the great arteries, and truncus arteriosus showed consistent deviations from normal values.</p><p><strong>Conclusion: </strong>The AV valve insertion angle was a stable parameter throughout gestation and demonstrates significant deviation in fetuses with CHD. This measurement may serve as a useful screening tool for early prenatal identification of certain structural CHD.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"36 4","pages":"418-424"},"PeriodicalIF":1.1,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13600625/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149038795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two-dimensional Speckle-Tracking and Four-dimensional Echocardiographic Evaluation of Cardiac Involvement in Post-COVID-19 patients: Comparison of Symptomatic and Asymptomatic Groups.","authors":"Kareem Muhammed Alaraby Hussein Sholkamy, Azza Abdel Moniem Farrag, Abdalla Amin Elagha, Fatema Eissa Qaddoura, Mohsen Salah Abdelazeem Mahmoud Nahla, Khalid Abdulraheem Al Faraidy, Noureldin Hamdan Samhoon Sahal, Salma Albahrani, Wefag Abdelazeem Mustafa Elsuni, Fathia Adel Abdo Samter","doi":"10.4103/jcecho.jcecho_167_25","DOIUrl":"https://doi.org/10.4103/jcecho.jcecho_167_25","url":null,"abstract":"<p><strong>Context: </strong>Subclinical myocardial dysfunction may follow mild COVID-19, highlighting the importance of early detection.</p><p><strong>Aims: </strong>To evaluate cardiac involvement in recently recovered COVID-19 patients using two-dimensional speckle-tracking echocardiography (2D-STE) and four-dimensional-transthoracic echocardiography (4D-TTE), comparing symptomatic and asymptomatic groups.</p><p><strong>Settings and design: </strong>This study involves a prospective observational cohort study at a tertiary cardiac center.</p><p><strong>Subjects and methods: </strong>Ninety-four adults (mean age 37 ± 7.5 years) post-COVID-19 recovery underwent echocardiographic evaluation at 1 and 3 months. Assessments included left and right ventricular (RV) function, myocardial strain using 2D STE, and left ventricular volumes and ejection fraction using 4D TTE.</p><p><strong>Statistical analysis: </strong>Paired and independent <i>t</i>-tests were applied, with statistical significance set at <i>P</i> < 0.05.</p><p><strong>Results: </strong>Statistically significant improvement was observed over time. Left ventricular end-diastolic volume decreased from 89.3 ml to 84.7 ml, left ventricular end-systolic volume from 31.9 ml to 29.4 ml, left ventricular ejection fraction (LVEF) increased from 64.8% to 66.0%, and left ventricular-global longitudinal strain improved from -23.8% to -24.7% (all <i>P</i> < 0.001). 4D-TTE confirmed parallel reductions in left ventricular volumes and an LVEF increase from 62.8% to 64.5% (<i>P</i> ≤ 0.002). RV functional parameters improved, RV end-systolic area (6.19 cm-5.71 cm), RV-fractional area change (52.1%-54.4%), and RV-longitudinal strain (-26.5% to -27.9%) (all <i>P</i> < 0.001). Symptomatic patients had lower LVEF at baseline (63.4% vs. 65.2%, <i>P</i> = 0.004) and follow-up (64.3% vs. 66.1%, <i>P</i> = 0.032); these findings should be interpreted cautiously due to the limited subgroup size.</p><p><strong>Conclusions: </strong>Mild or asymptomatic COVID-19 infections may cause temporary cardiac dysfunction. 2D-STE and 4D-TTE are sensitive tools for early detecting subclinical myocardial involvement and guiding follow-up care.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"36 3","pages":"295-303"},"PeriodicalIF":1.1,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13485258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148793570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interaction Effects of Age and Sex on Left Atrial Phasic Function in Patients with ST-Elevation Myocardial Infarction: A Two-dimensional Speckle-tracking Echocardiography.","authors":"Tahereh Haghighi, Ali Hosseinsabet, Reza Mohseni-Badalabadi","doi":"10.4103/jcecho.jcecho_18_26","DOIUrl":"10.4103/jcecho.jcecho_18_26","url":null,"abstract":"<p><strong>Objectives: </strong>We aimed to investigate the impact of age, sex, and their interaction effects on left atrial (LA) phasic function in patients with ST-elevation myocardial infarction (STEMI).</p><p><strong>Methods: </strong>A total of 169 men (84%) and 31 women (16%) who presented with STEMI were included consecutively. LA phasic function was evaluated using two-dimensional speckle-tracking echocardiography.</p><p><strong>Results: </strong>LA strain and strain rate during the reservoir phase and strain rate during the conduit phase decreased with increasing age in men (β = -0.21, β = -0.19, and β = -0.36, respectively) and in women (β = -0.59, β = -0.57, and β = -0.44, respectively). LA strain during the conduit phase decreased with increasing age in men (β = -0.27), and LA strain and strain rate during the contraction phase lessened in women (β = -0.62 and β = -0.58, respectively) (all <i>P</i> < 0.05). The interaction of age and sex on LA strain and strain rate during the reservoir (B = 0.33 and B = 0.04, respectively) and contraction (B = 0.34 and B = 0.08, respectively) phases was statistically significant, but not during the conduit phase.</p><p><strong>Conclusion: </strong>Our findings indicate that in patients with acute STEMI during the early period, LA reservoir function decreases with increasing age in both sexes, with a higher rate in women, and LA contraction function declines with age only in women. There was no significant difference between men and women in terms of LA conduit function, which declined at the same rate in both sexes with age.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"36 4","pages":"425-437"},"PeriodicalIF":1.1,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13600634/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149038811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adult ALCAPA Presenting with Apical Left Ventricular Aneurysm and Ventricular Arrhythmia.","authors":"Fushun Liao, Huan Lu, Haili Sun, Songlin Peng, Yuguang You","doi":"10.4103/jcecho.jcecho_119_25","DOIUrl":"10.4103/jcecho.jcecho_119_25","url":null,"abstract":"<p><p>Anomalous left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital cardiac anomaly. Most affected infants develop significant symptoms shortly after birth and require early intervention to improve survival. However, a small subset of patients develops extensive collateral circulation, which may mask myocardial ischemia and, in very rare cases, allow them to reach adulthood without obvious cardiac symptoms. We report such a case in which a patient presented with mild chest discomfort during a routine examination at our hospital. Multimodality imaging, including echocardiography and contrast-enhanced computed tomography (CT), three-dimensional CT reconstruction, confirmed the diagnosis of ALCAPA syndrome. The patient subsequently underwent Takeuchi repair, preventing future adverse cardiovascular events or chronic left ventricular dysfunction.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"36 2","pages":"171-177"},"PeriodicalIF":1.1,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13322595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148368287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiographic Features of Left Bundle Branch Area Pacing in a Patient with Concomitant Lamin and SCN5A Cardiomyopathy.","authors":"Shing Ching, Alexson Tsz-Ki Lau","doi":"10.4103/jcecho.jcecho_19_26","DOIUrl":"10.4103/jcecho.jcecho_19_26","url":null,"abstract":"<p><p>We report the echocardiographic features of the first case of left bundle branch area pacing (LBBAP) in a woman with concurrent lamin and SCN5A mutations presenting with familial heart block. Left ventricular ejection fraction, global longitudinal strain, myocardial work, and septal-to-posterior activation pattern were conserved at 3 months postimplantation with excellent pacing parameters, demonstrating feasibility and short-term preservation of left ventricular mechanics of LBBAP in this very rare disease.</p>","PeriodicalId":15191,"journal":{"name":"Journal of Cardiovascular Echography","volume":"36 4","pages":"467-471"},"PeriodicalIF":1.1,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13600642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149038544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}