Journal of applied physiology最新文献

{"title":"Do changes in cerebral blood flow modulate the amplitudes of P300 during cognitive task?","authors":"Shigehiko Ogoh, Hiroki Nakata, Hiroko Kubo, Manabu Shibasaki","doi":"10.1152/japplphysiol.00351.2024","DOIUrl":"https://doi.org/10.1152/japplphysiol.00351.2024","url":null,"abstract":"Journal of Applied Physiology, Ahead of Print. <br/>","PeriodicalId":15160,"journal":{"name":"Journal of applied physiology","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142221677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Middle cerebral artery blood velocity and end-tidal carbon dioxide responses to moderate intensity cycling in children, adolescents and adults","authors":"Max E. Weston, Alan R. Barker, Owen W. Tomlinson, Jeff S. Coombes, Tom G. Bailey, Bert Bond","doi":"10.1152/japplphysiol.00688.2023","DOIUrl":"https://doi.org/10.1152/japplphysiol.00688.2023","url":null,"abstract":"Journal of Applied Physiology, Ahead of Print. <br/>","PeriodicalId":15160,"journal":{"name":"Journal of applied physiology","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142221676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fingolimod, a Sphingosine-1-Phosphate Receptor Modulator Prevents Neonatal Bronchopulmonary Dysplasia and subsequent Airway Remodeling in a Murine Model","authors":"Tara Sudhadevi, Akanksha Annadi, Prathima Basa, Anjum Jafri, Viswanathan Natarajan, Anantha Harijith","doi":"10.1152/japplphysiol.00311.2024","DOIUrl":"https://doi.org/10.1152/japplphysiol.00311.2024","url":null,"abstract":"Journal of Applied Physiology, Ahead of Print. <br/>","PeriodicalId":15160,"journal":{"name":"Journal of applied physiology","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142227301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of computational fluid dynamics to investigate pathophysiological mechanisms in exercise-induced laryngeal obstruction","authors":"Luke Reid, Jens Thougaard, Oliver J. Price, Masoud Hayatdavoodi, Lars Pedersen, Emil Walsted","doi":"10.1152/japplphysiol.00230.2024","DOIUrl":"https://doi.org/10.1152/japplphysiol.00230.2024","url":null,"abstract":"Journal of Applied Physiology, Ahead of Print. <br/>","PeriodicalId":15160,"journal":{"name":"Journal of applied physiology","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142221678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex-based differences in the blood pressure responses to muscle metaboreflex activation are consistent between limb and respiratory muscle","authors":"Jenna M. Benbaruj, Michael G. Leahy, Rachel Jackman, Thora Rae, Robert Boushel, Glen E. Foster, A. William Sheel","doi":"10.1152/japplphysiol.00187.2024","DOIUrl":"https://doi.org/10.1152/japplphysiol.00187.2024","url":null,"abstract":"Journal of Applied Physiology, Ahead of Print. <br/>","PeriodicalId":15160,"journal":{"name":"Journal of applied physiology","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142221680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral sodium lactate ingestion does not increase blood lactate concentrations and is accompanied by moderate to severe gastrointestinal side effects","authors":"Seth F. McCarthy, Derek P. D. Bornath, Jessica A. L. Tucker, Tom J. Hazell","doi":"10.1152/japplphysiol.00536.2024","DOIUrl":"https://doi.org/10.1152/japplphysiol.00536.2024","url":null,"abstract":"Journal of Applied Physiology, Ahead of Print. <br/>","PeriodicalId":15160,"journal":{"name":"Journal of applied physiology","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142227302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transvenous Phrenic Nerve Stimulation Reduces Diaphragm Injury During Controlled Mechanical Ventilation In A Preclinical Model of ARDS","authors":"Elizabeth C. Rohrs, Karl C. Fernandez, Thiago G. Bassi, Michelle Nicholas, Jessica Wittmann, Marlena Ornowska, Matt Gani, Isabella Dakin, Steven C. Reynolds","doi":"10.1152/japplphysiol.00884.2023","DOIUrl":"https://doi.org/10.1152/japplphysiol.00884.2023","url":null,"abstract":"Journal of Applied Physiology, Ahead of Print. <br/>","PeriodicalId":15160,"journal":{"name":"Journal of applied physiology","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142221675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Gravity: An Effective Countermeasure for Microgravity-Induced Headward Fluid Shift?","authors":"Larry A. Kramer, Khader M. Hasan, Xu Zhang, Edwin Mulder, Darius A. Gerlach, Karina Marshall-Goebel, Brandon R. Macias, Steven S. Laurie, Gary Strangman, Raj Iyer, Eric M. Bershad","doi":"10.1152/japplphysiol.00441.2024","DOIUrl":"https://doi.org/10.1152/japplphysiol.00441.2024","url":null,"abstract":"Journal of Applied Physiology, Ahead of Print. <br/>","PeriodicalId":15160,"journal":{"name":"Journal of applied physiology","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142221679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carbon monoxide Supplementation: Evaluating its Potential to Enhance Altitude Training Effects and Cycling Performance in Elite Athletes.","authors":"Tomas Urianstad, Simone Villanova, Ingvill Odden, Joar Hansen, Knut Sindre Mølmen, Simone Porcelli, Bent R Rønnestad, Daniele A Cardinale","doi":"10.1152/japplphysiol.00469.2024","DOIUrl":"https://doi.org/10.1152/japplphysiol.00469.2024","url":null,"abstract":"<p><p>Altitude training is a cornerstone for endurance athletes for improving blood variables and performance with optimal effects observed at ⁓2300-2500 meters above sea level (m.a.s.l.). However, elite cyclists face challenges such as limited access to such altitudes, inadequate training facilities, and high expenses. To address these issues, a novel method involving daily exposure to carbon monoxide (CO) has been proposed to amplify altitude training adaptations at suboptimal altitudes. Thirty-one male cyclists were assigned to three groups: Live-High and Train-High with CO inhalation (LHTH_CO), Live-High Train-High (LHTH), and Live-Low Train-Low (LLTL). The LHTH_CO group underwent CO inhalation twice daily in the afternoon/evening to elevate carboxyhemoglobin concentration to ⁓10%. Hematological variables, in-vivo muscle oxidative capacity, and physiological indicators of cycling performance were assessed before and after a 3-week altitude training camp at 2100 m.a.s.l. LHTH_CO demonstrated a larger increase in hemoglobin mass (Hb_mass) compared to both LHTH and LLTL. While there were no statistical differences between LHTH_CO and LHTH in submaximal and maximal performance measures, LHTH_CO displayed greater improvements in 1-min maximal power output during incremental testing (W_max), power output at lactate threshold, and maximal oxygen consumption (VO_2max) compared to LLTL. LHTH demonstrated a larger improvement than LLTL in W_max andVO_2maxwith no group differences in Hb_mass or submaximal measures. Muscle oxidative capacity did not differ between groups. These findings suggest that combining moderate altitude training with daily CO inhalation promotes hematological adaptations more effectively than moderate altitude alone and enhances cycling performance metrics in cyclists more than sea-level training.</p>","PeriodicalId":15160,"journal":{"name":"Journal of applied physiology","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ANKLE TORQUE VARIANCE IS A BETTER INDICATOR OF BALANCE CONTROL PERFORMANCE THAN PLANTAR PERCEPTUAL SENSITIVITY THRESHOLD.","authors":"Frederic Jf Viseux, Maxime Billot, Grant Handrigan, Martin Simoneau","doi":"10.1152/japplphysiol.00091.2024","DOIUrl":"https://doi.org/10.1152/japplphysiol.00091.2024","url":null,"abstract":"<p><p>We explored whether ankle torque variability or plantar perceptual threshold explains human balance control more effectively. We hypothesized that ankle torque variance is a better indicator of center of pressure (COP) velocity variance than plantar perceptual sensitivity. Two conditions were tested: loaded (23 kg vest added) and unloaded, as loading should diminish plantar sensitivity and increase COP velocity variability. We created a linear feedback model to assess the noise change in the sensorimotor loop induced by loading. Plantar sensitivity was quantified using a psychophysical approach while participants stood barefoot. A linear motor applied a force impulse on the participant's heel. A 'yes-no' method of limits was selected to identify plantar sole sensory thresholds in both conditions. We observed reduced plantar sensitivity in loaded compared to unloaded conditions. In the loaded condition, participants exhibited greater COP velocity variance, with significant positive Pearson's correlations confirming a substantial association between ankle torque and COP velocity variances for both loaded (variance accounted for (VAR): r² = 44.56%, p = 0.018) and unloaded conditions (VAF: r² = 58.83 %, p = 0.004). No significant correlation existed between COP velocity variance and plantar sensitivity threshold for both loaded (VAF: r² = 0.002 %, p = 0.99) and unloaded conditions (VAF: r² = 21.81%, p = 0.35). The model confirmed a ~88% rise in sensorimotor loop noise in the loaded condition. Ankle torque variance assesses the precision of non-perceptual and perceptual detection mechanisms in evaluating whole-body motions and the accuracy in converting sensory cues into ankle torque.</p>","PeriodicalId":15160,"journal":{"name":"Journal of applied physiology","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}