Journal of Ayurveda and Integrative Medicine最新文献

{"title":"Research status of traditional & complementary medicine systems across the world","authors":"Vedvati Bhapkar ,&nbsp;Vallari Nisargand ,&nbsp;Pawankumar Godatwar ,&nbsp;Supriya Bhalerao","doi":"10.1016/j.jaim.2024.101078","DOIUrl":"10.1016/j.jaim.2024.101078","url":null,"abstract":"<div><h3>Background</h3><div>Despite strong presence of biomedicine, traditional and complementary medicine (T &amp; CM) systems have sustained with their multidimensional connect with people. However, their scientific acceptance and mainstreaming falls short due to inadequacies in research. Also, available reports in this regard scarcely focus on their individuality and present them as a consolidated entity.</div></div><div><h3>Objectives</h3><div>The present study was carried out to elucidate individual research status of certain WHO- acknowledged T &amp; CM systems in a customized framework of indirect indicators.</div></div><div><h3>Material and methods</h3><div>The research status of selected systems was assessed on basis of quantitative indicators viz., research dissemination outcomes concerned with scientific documents and researchers, contribution in COVID-19 prevention and management, and patents profile.</div></div><div><h3>Results</h3><div>Systems such as Traditional Chinese Medicine and Acupuncture fare better than most others. The number of documents in multidisciplinary SCOPUS database was larger than those in PubMed, a healthcare database for almost all systems. Out of 28 lead authors, half belonged to developed countries, viz., USA and Germany. Highest citation count was recorded for TCM (n = 2238). Of the 105 journals analyzed, 40 were not dedicated to specific T &amp; CM system. Most number of discretely dedicated journals (n = 20) mentioned TCM as primary scope. Cochrane systematic reviews (n = 142) and protocols (n = 33) were highest for Acupuncture, while many systems had zero presence. Maximum COVID-19 related clinical studies were registered for TCM (n = 335), followed by Ayurveda (n = 112). TCM related patents were also highest among all.</div></div><div><h3>Conclusion</h3><div>There is a huge variation in the research status of different T &amp; CM systems. The stakeholders of these systems need to establish a strong evidence base at par with biomedicine. United efforts at global level through organizations such as WHO-Global Traditional Medicine Centre (GTMC) might be helpful in this regard.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 2","pages":"Article 101078"},"PeriodicalIF":1.7,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143350745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of the radioprotector chlorophyllin on graft versus leukemia response in experimental allogeneic hematopoietic stem cell transplantation","authors":"Saurabh Kumar Gupta ,&nbsp;Subhash Yadav ,&nbsp;Deepak Sharma ,&nbsp;Santosh Kumar Sandur ,&nbsp;Navin Khattry ,&nbsp;Jayant Sastri Goda ,&nbsp;Vikram Gota","doi":"10.1016/j.jaim.2024.101109","DOIUrl":"10.1016/j.jaim.2024.101109","url":null,"abstract":"","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 2","pages":"Article 101109"},"PeriodicalIF":1.7,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143260022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacological effects of herbal ingredients of Manasamitra vatakam in the treatment of Alzheimer's disease: A review","authors":"Anju C. Nair ,&nbsp;Beena Briget Kuriakose ,&nbsp;Aswini Biju ,&nbsp;Sarika Surendran ,&nbsp;M.S. Sudheesh ,&nbsp;P.K. Lakshmi","doi":"10.1016/j.jaim.2024.101041","DOIUrl":"10.1016/j.jaim.2024.101041","url":null,"abstract":"<div><div>Multi-targeted drug therapy has received substantial attention for the treatment of diseases of multi-factorial origin, including neurodegenerative and autoimmune diseases. It seems reasonable to argue that the complex pathology of neurodegenerative diseases (ND) cannot be reduced to a single target to modulate a broad range of cellular signaling, associated pathologies, and symptoms. It is this idea that has brought the attention of the scientific world towards phytochemicals and traditional drugs that are notoriously multi-targeted. A systematic study of these formulations and establishing the molecular pathways of individual molecules can lead to a standardized multi-component product that can modulate a broad range of activities on different targets of ND. This could provide an accessible and affordable solution to the significant disease burden of ND. With this idea in mind, a systematic review was carried out on an Ayurvedic product <em>Manasamitra Vatakam (</em>MMV), known to be a neuroprotective formulation and highly effective against Alzheimer's disease. MMV can be a source of phytomolecules for treating neurodegenerative diseases. The multifactorial nature of these diseases makes them suitable candidates for testing phytochemicals due to the inherent multitargeting capabilities of these compounds. The primary objective of this review is to provide a comprehensive understanding of the phytomolecules from MMV that are responsible for its multitargeted effect against neurodegenerative diseases. From the reported literature, it is clear that many phytoconstituents and extracts of the herbal ingredients from MMV have demonstrated their efficacy against AD models. However, the combination of these molecules in AD models has never been tested. Scientific studies should be done to explore the bioactive compounds in the formulation and the druggability of these identified compounds can be evaluated using experimental methods.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 1","pages":"Article 101041"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11773069/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The potency of ethyl acetate fraction of cempedak (Artocarpus champeden) leaves in attenuating the nephrotoxic effect in gentamicin-piroxicam-induced rat models","authors":"Fitrya ,&nbsp;Elfita ,&nbsp;Syafrina Lamin ,&nbsp;Fima Amalia Ashfa ,&nbsp;Rennie Puspa Novita ,&nbsp;Annisa Amriani","doi":"10.1016/j.jaim.2024.101040","DOIUrl":"10.1016/j.jaim.2024.101040","url":null,"abstract":"<div><h3>Background</h3><div>Nephrotoxicity is a condition characterized by a decline in kidney function due to the toxic effects of medications and substances, such as the nephrotoxic antibiotic gentamicin. <em>Artocarpus champeden</em> is a traditional medicinal plant that is commonly found in Indonesia.</div></div><div><h3>Objective</h3><div>This study aims to evaluate the potential of the ethyl acetate fraction of <em>Artocarpus champeden</em> leaves (FEC) in improving kidney function in an animal model of nephrotoxicity induced by gentamicin and piroxicam.</div></div><div><h3>Materials and Methods</h3><div>Three groups of animals were treated with FEC at dosages of 125, 250, and 500 mg/kg BW orally for four weeks following induction with 100 mg/kg gentamicin (Gen) intraperitoneally and 3.6 mg/kg piroxicam (Prx) orally. The nephroprotective effect of FEC was compared with the NaCMC (5%), ketosteril (55 mg/kg), and untreated groups as the normal, positive, and negative controls, respectively. The kidney biochemical examinations and histopathological analysis were conducted on the last day.</div></div><div><h3>Results</h3><div>Compared to the negative control group, FEC-treated animals showed significant improvement in kidney function, correlating with increasing doses. The test group also exhibited increased creatinine clearance and improved cell structure, comparable to samples treated with ketosteril. The nephroprotective effect of FEC is likely attributed to its flavonoid content, acting through antioxidant and anti-inflammatory mechanisms.</div></div><div><h3>Conclusion</h3><div>The ethyl acetate fraction of <em>A. champeden</em> leaves demonstrated nephroprotective activity and has potential as a therapeutic agent for kidney damage and hypertension from natural sources.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 1","pages":"Article 101040"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11773062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Terminalia catappa aqueous extract reduces hyperglycaemia and oxidative stress in diabetic-hypercholesterolemic rats","authors":"Ojaskumar D. Agrawal ,&nbsp;Yogesh A. Kulkarni","doi":"10.1016/j.jaim.2024.101025","DOIUrl":"10.1016/j.jaim.2024.101025","url":null,"abstract":"<div><h3>Background</h3><div><em>Terminalia catappa</em> is an important medicinal plant. Plants from the genus <em>Terminalia</em> have been reported for antidiabetic effects.</div></div><div><h3>Objective</h3><div>To study effect of <em>Terminalia catappa</em> leaves aqueous extract in type 2 diabetic rats.</div></div><div><h3>Materials and methods</h3><div>High-fat diet (HFD) and a low dose of streptozotocin (35 mg/kg, <em>i.p.</em>) were used for inducing type 2 diabetes in rats; streptozotocin was injected after two weeks of dietary modification with HFD. HFD was continued throughout the study. Doses of 500 and 1000 mg/kg of aqueous extract of <em>Terminalia catappa</em> were used as a treatment for six weeks. At the end of the study, biochemical and oxidative stress parameters were estimated. Histopathology and immunohistochemistry of pancreatic tissue were performed.</div></div><div><h3>Results</h3><div>Significant decrease (<em>p</em> &lt; 0.01, p &lt; 0.001) was observed in glucose levels of diabetic animals treated with <em>T. catappa</em> extract at both dose levels when compared with diabetic control group. Treatment with aqueous extract reduced cholesterol levels significantly (<em>p</em> &lt; 0.05). After receiving 1000 mg/kg of extract, the triglyceride level was significantly lowered (<em>p</em> &lt; 0.01) in the diabetic rats. Extract treatment enhanced the insulin sensitivity index (ISI), while insulin levels and HOMA-IR were markedly reduced. Treatment with 1000 mg/kg of extract significantly enhanced the levels of GSH and catalase. Histopathological analysis of the pancreas showed that damage caused by hyperglycemia was prevented in the extract-treated groups. Pancreatic tissue showed an increased expression of SIRT1 in extract-treated animals.</div></div><div><h3>Conclusion</h3><div>The current study's findings prove that the extract has remarkable antidiabetic effects.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 1","pages":"Article 101025"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787580/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Programming a healthier future","authors":"Bhushan Patwardhan ,&nbsp;Preeti Chavan-Gautam ,&nbsp;Sarika Chaturvedi","doi":"10.1016/j.jaim.2025.101133","DOIUrl":"10.1016/j.jaim.2025.101133","url":null,"abstract":"","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 1","pages":"Article 101133"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143349562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Chronic Plaque Psoriasis through Panchkarma: A case report","authors":"Rohan Agalcha,&nbsp;Sarvesh Kumar Singh,&nbsp;Kshipra Rajoria","doi":"10.1016/j.jaim.2024.101072","DOIUrl":"10.1016/j.jaim.2024.101072","url":null,"abstract":"<div><div>Psoriasis is a chronic systemic inflammatory skin disorder prevailing in 2%–3% individuals worldwide. Yet no permanent management has been established. Metabolic burdens and comorbidities have been found to be associated with Psoriasis, which make it more critical. The classical management of the disease in Ayurveda includes <em>Vamana Karma</em> (therapeutic emesis) and <em>Virechana Karma</em> (therapeutic purgation). This is a distinct case where a 52-year-old patient, suffering from Chronic Plaque Psoriasis (CPP), unfit for <em>Vamana Karma</em> was treated by <em>Virechana</em> <em>Karma</em> only. The patient had suffered from Psoriasis since last 14 years and was present with symptoms of scaly lesions and intense itching. The patient was admitted in the IPD and planned for <em>Virechana Karma</em>. After <em>Shodhana</em>, <em>Rasamanikya</em>-125 mg, <em>Vidanga Choorna</em> 2 gm, <em>Kaishora Guggulu</em>-1000 mg, <em>Kamdudha Rasa</em> 250 mg, <em>Khadiraris</em><em>h</em><em>ta</em>-20 ml, and <em>Punarnavadi Kwatha</em> 40 ml, twice a day was advised with daily 3 times local application of <em>Bruhad Marichyadi Taila</em> as regular medication. The assessment was done by Psoriasis Area Severity Index (PASI) score, Dermatology Life Quality Index (DLQI) score and Numerical Rating Scale (NRS) for itching. The initial PASI, DLQI and NRS scores were 20.6, 18, and 8 respectively which was evaluated to be, 5.8, 4 and 2 respectively in the latest follow-up. This case study demonstrates that <em>Virechana</em> alone may also manage CPP.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 1","pages":"Article 101072"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787006/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adjunct Ayurvedic treatment providing more than 10 years of disease-free survival in a rare case of male breast cancer patient with high-grade invasive ductal cell carcinoma - A Case Report","authors":"Vineeta Deshmukh,&nbsp;Sadanand Sardeshmukh,&nbsp;Arvind Kulkarni,&nbsp;Vidya Gupta,&nbsp;Shweta Gujar,&nbsp;Bhagyashree Sardeshmukh,&nbsp;Nilambari Sardeshmukh,&nbsp;Dhananjay Deshpande,&nbsp;Keyur Gutte,&nbsp;Vinita Awalkanthe,&nbsp;Anjali Deshpande,&nbsp;Shrikant Kulkarni","doi":"10.1016/j.jaim.2024.100982","DOIUrl":"10.1016/j.jaim.2024.100982","url":null,"abstract":"<div><h3>Introduction</h3><div>Male breast cancer (MBC) is an uncommon malignancy. In spite of conventional Allopathic treatment, long-term disease-free survival (DFS) of more than 10 years in MBC is rare, due to its aggressive nature.</div></div><div><h3>Case presentation</h3><div>We report a case of 56 years old, stage IIB and grade III invasive ductal cell carcinoma MBC (Lt) patient, operated for left modified radical mastectomy with axillary clearance followed by six cycles of chemotherapy during October 2010–January 2011. Patient was on hormonal treatment from March 2011 till May 2021. He opted for adjunct <em>Ayurvedic</em> treatment throughout the conventional treatments for the period of 10 years. Ayurvedic treatment in the form of treatment for pacifying imbalanced humors (<em>Doshas</em>) and disease (<em>Shamana chikitsa</em>) and treatment for immunomodulation (<em>Rasayana Chikitsa</em>); and periodic detoxifying treatment (<em>Panchakarma Chikitsa</em>) was given in this patient. He was also advised healthy diet and lifestyle at our center. The treatment chosen was mainly to reduce side effects of chemotherapy like anorexia, nausea, vomiting, constipation, diarrhoea, taste disturbance, mucositis, fatigue and fever. It also helped in improving quality of life and increasing DFS.</div></div><div><h3>Conclusion</h3><div>The long DFS of 10 years and 3 months with good Quality of Life and minimal side effects of conventional cancer therapy could be ascribed to the adjunct Ayurvedic treatment given to this patient. We have to observe the benefits in more number of patients in future to define usefulness of this treatment modality.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 1","pages":"Article 100982"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute oral toxicity evaluation of synbiotic mixture containing Streptococcus salivarius K12 and Musa acuminata aqueous peel extract in Sprague-Dawley rats","authors":"Aalina Sakiinah Mohd Fuad ,&nbsp;Mohd Hafiz Arzmi ,&nbsp;Muhammad Ekmal Bakar ,&nbsp;Izatus Shima Taib ,&nbsp;Fazle Khuda ,&nbsp;Nurrul Shaqinah Nasruddin","doi":"10.1016/j.jaim.2024.101037","DOIUrl":"10.1016/j.jaim.2024.101037","url":null,"abstract":"<div><h3>Background</h3><div>The combination of S. salivarius K12 and M. acuminata are being used as synbiotic, but its safety evaulation is required.</div></div><div><h3>Objective</h3><div>This study aimed to determine the LD50 of synbiotic containing probiotic <em>Streptococcus salivarius</em> K12 and prebiotic <em>Musa acuminata</em> peel extract.</div></div><div><h3>Materials and Methods</h3><div>The determination of LD50 is done according to the Acute Oral Toxicity test No. 425 (AOT425). For limit test, five female Sprague Dawley rats were given a limit dose of 2000 mg/kg of the synbiotic mixture once orally, and observed for 12 days. For subacute toxicity test, twenty female Sprague Dawley rats were randomised into 4 groups (n = 5). Control group received saline, others received synbiotic mixture at doses 175 mg/kg, 550 mg/kg, and 2000 mg/kg, respectively, and observed for 14 days. Animals were euthanised on day-15, blood was collected, and subjected to haematological and biochemical analyses. Kidney and liver were preserved for histopathological examination.</div></div><div><h3>Result</h3><div>No significant changes on the average body weight of the animals throughout the study. Haematological parameters and biochemical analysis do not depict any changes related to acute toxicity. Histopathology analysis depicted mild changes on kidney and liver.</div></div><div><h3>Conclusion</h3><div>Based on the data, the LD50 of the synbiotic formulation is higher than 2000 mg/kb, with no sign of acute toxicity observed on all parameters.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 1","pages":"Article 101037"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11714393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142835777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular dynamics directed neuroprotective activity of alcoholic extract of Garuga pinnata Roxb. in experimental rats","authors":"Shinge Jagannath ,&nbsp;Walhekar Vinayak ,&nbsp;Muthal Amol ,&nbsp;Pamu Sandhya ,&nbsp;Chandrashekar V.M ,&nbsp;Shinde Vaibhav ,&nbsp;Ravindra Kulkarni","doi":"10.1016/j.jaim.2024.101032","DOIUrl":"10.1016/j.jaim.2024.101032","url":null,"abstract":"<div><div><strong>Background:</strong> <em>Garuga pinnata</em> Roxb., a member of family Burseraceae, is a commonly grown plant in south east Asia including India in tropical rain forests predominately. Apart from folkloric use, important anti-inflammatory and antiasthamatic activity of this plant has been revealed. <strong>Objective:</strong> This study is aimed to know neuroprotective effects of ethanolic extracts which is based on the computationally determined NMDA as molecular target. <strong>Material and Methods:</strong> Well dried ethanolic extract of leaves was examined for the presence of amentoflavone with LC-MS/MS which offered the fragments those mimicked the fragmentation of amentoflavone. Effect of ethanolic extract was studies by dividing experimental rat groups each consisting of six animals into sham group, control group, GPE 200 mg/kg and GPE 400 mg/kg groups and were operated for hassle free administration of colchicine. The pharmacological study involved Morris water maze test, Elevated plus maze test and Open Field Box Test. <strong>Results:</strong> In Morris water maze test, both the selected doses of extracts showed significant decrease in the mean escape latencies upon colchicine challenge. Similarly, in both the doses of the extract showed improved motor and grooming effects in elevated plus maze test upon colchicine injection and also significant ambulatory movements were recorded in open field box test too. <strong>Conclusion:</strong> The ethanolic extracts of <em>Garuga pinnata</em> on the experimental animals showed significant restoration of the memory capacity of the tested animals, thus the computationally explored insights and pharmco-behavioral screening were quite closure to each other.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 1","pages":"Article 101032"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142894647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}