Journal of Ayurveda and Integrative Medicine最新文献

{"title":"Molecular dynamics directed neuroprotective activity of alcoholic extract of Garuga pinnata Roxb. in experimental rats","authors":"Shinge Jagannath ,&nbsp;Walhekar Vinayak ,&nbsp;Muthal Amol ,&nbsp;Pamu Sandhya ,&nbsp;Chandrashekar V.M ,&nbsp;Shinde Vaibhav ,&nbsp;Ravindra Kulkarni","doi":"10.1016/j.jaim.2024.101032","DOIUrl":"10.1016/j.jaim.2024.101032","url":null,"abstract":"<div><div><strong>Background:</strong> <em>Garuga pinnata</em> Roxb., a member of family Burseraceae, is a commonly grown plant in south east Asia including India in tropical rain forests predominately. Apart from folkloric use, important anti-inflammatory and antiasthamatic activity of this plant has been revealed. <strong>Objective:</strong> This study is aimed to know neuroprotective effects of ethanolic extracts which is based on the computationally determined NMDA as molecular target. <strong>Material and Methods:</strong> Well dried ethanolic extract of leaves was examined for the presence of amentoflavone with LC-MS/MS which offered the fragments those mimicked the fragmentation of amentoflavone. Effect of ethanolic extract was studies by dividing experimental rat groups each consisting of six animals into sham group, control group, GPE 200 mg/kg and GPE 400 mg/kg groups and were operated for hassle free administration of colchicine. The pharmacological study involved Morris water maze test, Elevated plus maze test and Open Field Box Test. <strong>Results:</strong> In Morris water maze test, both the selected doses of extracts showed significant decrease in the mean escape latencies upon colchicine challenge. Similarly, in both the doses of the extract showed improved motor and grooming effects in elevated plus maze test upon colchicine injection and also significant ambulatory movements were recorded in open field box test too. <strong>Conclusion:</strong> The ethanolic extracts of <em>Garuga pinnata</em> on the experimental animals showed significant restoration of the memory capacity of the tested animals, thus the computationally explored insights and pharmco-behavioral screening were quite closure to each other.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 1","pages":"Article 101032"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142894647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-inflammatory activity and selective inhibition of iNOS gene expression by a polyherbal formulation","authors":"Boyagoda Vidanelage Loshini Ravima Ranaweera ,&nbsp;Daniya Edward ,&nbsp;Jayamini Chathurika Harasgama ,&nbsp;Ajita Mahendra Abeysekera ,&nbsp;Ovitigala Vithanage Don Sisira Jagathpriya Weerasena ,&nbsp;Shiroma Mangalika Handunnetti","doi":"10.1016/j.jaim.2024.101049","DOIUrl":"10.1016/j.jaim.2024.101049","url":null,"abstract":"<div><h3>Background</h3><div>Link Samahan® (LS), a product of Link Natural Products (Pvt) Limited, Sri Lanka contains extracts of 14 medicinal plants. It is used as a prophylactic against cold and cold related symptoms. It has immunomodulatory activity, specifically enhancing the humoral immune response.</div></div><div><h3>Objective</h3><div>To investigate the anti-inflammatory activity (AIA) of LS and related mechanisms.</div></div><div><h3>Materials and methods</h3><div><em>In vivo</em> AIA was assessed by the inhibition of carrageenan-induced rat paw-edema. Mechanisms of AIA were assessed <em>in vitro</em> by the inhibition of reactive oxygen species (ROS) and reactive nitrogen species (RNS) production and expression of inducible nitric oxide synthase (iNOS) gene using rat peritoneal cells.</div></div><div><h3>Results</h3><div>LS showed an increasing inhibition in rat paw-edema up to 5 h compared to the biphasic pattern exhibited by the reference drug, Indomethacin. Inhibition by LS at the 1^st and 3^rd-5^th hours (44.7% and 73.0–74.6%) was comparable to indomethacin (47.4% and 83.6–76.5%; p &gt; 0.05) whereas at the 2^nd hour, LS exhibited a significantly higher inhibition compared to indomethacin (66.7% vs 28.6%; p &lt; 0.05). LS treatment significantly inhibited the ROS (superoxide; 47.2 ± 0.86%; p &lt; 0.05) and RNS (nitrite; 54.0 ± 0.40%; p &lt; 0.05) production in rat peritoneal cells. Further, specific inhibition of iNOS gene expression in rat peritoneal cells resulted in a significant reduction in RNS production whereas LS had lesser or no inhibitory effect on endothelial NOS and neuronal NOS gene expression.</div></div><div><h3>Conclusion</h3><div>LS has potent anti-inflammatory activity and selective inhibition of iNOS activity. AIA of LS shown here supports its use as a prophylactic against cold and cold related symptoms.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 1","pages":"Article 101049"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ayurvedic management of recurrent lumbar pain, disability, and leg pain after posterior decompression with transforaminal lumbar interbody fusion in prolapsed intervertebral disc: A case report","authors":"Satyajit Pandurang Kulkarni ,&nbsp;Pallavi Satyajit Kulkarni","doi":"10.1016/j.jaim.2024.101071","DOIUrl":"10.1016/j.jaim.2024.101071","url":null,"abstract":"<div><div>Prolapsed intervertebral disc (PIVD) can lead to debilitating pain and functional limitations. While surgical interventions like Transforaminal Lumbar Interbody Fusion (TLIF) are often employed, recurrence of symptoms is not uncommon. This case report presents the successful Ayurvedic management of a 45-year-old female who developed recurrent lumbar radiculopathy six months after TLIF for PIVD.</div><div>The patient presented with severe lumbar pain, disability, and bilateral leg discomfort. Diagnosed with “Prushthagraha” according to Ayurvedic principles, she underwent a 43-day treatment regimen. This included Ayurvedic medications and an initial eight-day course of Sarvanga Abhyanga-Mardana (therapeutic massage) and Swedana (sudation therapy).</div><div>Post-treatment, the patient demonstrated significant clinical improvement, evidenced by a substantial reduction in Oswestry Disability Index (ODI) and Visual Analogue Scale (VAS) scores for both lumbar and leg pain. Furthermore, her walking distance increased from 80 m to 1000 m.</div><div>This case highlights the potential of Ayurvedic interventions as a complementary approach for managing recurrent lumbar radiculopathy following surgical intervention for PIVD. However, further research with larger sample sizes and controlled study designs is warranted to validate these findings.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 1","pages":"Article 101071"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786815/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urine exosome biomarkers of obesity after Lekhana Basti treatment – Report of a pilot study","authors":"Bhavya Vijay ,&nbsp;Poornima Devkumar ,&nbsp;Gargi Saha ,&nbsp;Satish P. RamachandraRao","doi":"10.1016/j.jaim.2024.101043","DOIUrl":"10.1016/j.jaim.2024.101043","url":null,"abstract":"<div><h3>Background</h3><div>Obesity is a rising risk factor for various diseases including cardiovascular diseases and Cancer. The limitations of targeted obesity-treatment approaches employed in the clinic presently underscore the importance of developing integrative management strategies for identification of specific biomarkers of obesity. <strong>Objectives:</strong> Given the specificity of exosome/extracellular vesicle (EV) biomarkers, we aimed here to identify the EV biomarkers of Ayurveda treatment – <em>Lekhana Basti</em> – for Obesity.</div></div><div><h3>Methodology</h3><div>A total of eighteen 24-h urine samples from 6 participants with BMI&gt;30 kg/m² were used in this study, collected over 3 time-points during the Lekhana basti (medicated enema for obesity) treatment. Urine EV were isolated using Polyethylene Glycol (PEG). The proteins were resolved by 1-d gel electrophoresis and identified using liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) and quantified by label-free methods. Significant Protein-Protein Interactions, KEGG pathway analysis and enrichment, functional gene ontology (GO) annotation were identified and shortlisted in comparison to Obesity reference genes from DisGeNET.</div></div><div><h3>Results</h3><div>With UniProt as a reference subsequent to LC-MS/MS-identification, a total of 210 exosome proteins were identified. Seventy-three proteins were overexpressed in pathway enrichment analysis. Further, GO functional annotation identified 15 common proteins involved. Finally, the 8 hub proteins associated with obesity were identified and their differential expression profile compared between three different time-points during <em>Lekhana Basti</em> treatment. Six protein markers overexpressed during obesity were downregulated post <em>Lekhana Basti</em> treatment, while 2 markers increased in abundance post-treatment.</div></div><div><h3>Conclusion</h3><div>To our knowledge, this is the first study to isolate and identify urine EV protein abundance profiles from obese female participants of India. The study results indicate significant changes in the differential expression profile of 8 hub proteins involved in obesity, after <em>Lekhana Basti</em> treatment. The biomarker signature of the pilot study indicates the role of Ayurveda treatment and the possible pathways involved in the treatment of Obesity. Further, this study underlines the specificity of urine exosomes/EV as diagnostic markers as well as the potential of Ayurveda treatment in effective management of obesity.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 1","pages":"Article 101043"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mind relaxation effect of Jatamansi Taila Shirodhara on psychological distress in Triple Negative Breast Cancer (TNBC) patients - results of an open-labelled, randomised controlled clinical trial","authors":"Sadanand Sardeshmukh ,&nbsp;Vineeta Deshmukh ,&nbsp;Vasanti Godse ,&nbsp;Anaya Pathrikar ,&nbsp;Abhijeet Joshi ,&nbsp;Shweta Gujar ,&nbsp;Bhagyashri Sardeshmukh ,&nbsp;Anjali Deshpande ,&nbsp;Sushama Bhuvad","doi":"10.1016/j.jaim.2024.101069","DOIUrl":"10.1016/j.jaim.2024.101069","url":null,"abstract":"<div><h3>Background</h3><div>Triple-negative breast cancer (TNBC) is a subtype of breast cancer clinically defined as lacking expression of Estrogen receptor (ER), Progesterone receptor (PR), and Human Epidermal growth factor Receptor (HER2). Psychological distress is a major risk factor of TNBC, patients diagnosed with TNBC are under tremendous stress due to the aggressive nature of the disease. Stress hormones decrease the efficacy of therapeutics. These facts underscore the need for mind relaxation treatment for TNBC patients.</div></div><div><h3>Objectives</h3><div>To find out the anti-anxiety activity of the <em>Jatamansi Taila</em> in TNBC patients.</div></div><div><h3>Material and methods</h3><div>This was a two-arm, open-labelled, parallel, prospective controlled clinical study, conducted on 70 patients of TNBC in the age group of 20–70 years who have completed conventional therapy and opted for Ayurvedic Treatment. Patients were divided into 2 groups. Thirty-five patients in Group A were treated with Oral Ayurvedic Medicines (<em>Shamana Chikitsa</em>) and <em>Jatamansi Taila Shirodhara</em>; whereas 35 patients in Group B were treated with only Oral Ayurvedic Medicines.</div></div><div><h3>Results</h3><div><em>Jatamansi Taila Shirodhara</em> was found to be effective in relieving symptoms of Anxiety and Psychological distress (<em>Chittodvega</em>) immediately after the procedure, viz. sleep disturbance, difficulty in concentration, and fearfulness. <em>Jatamansi Taila Shirodhara</em> was found to be highly effective in improving Quality of Life (QoL), especially in improving functional ability, well-being and reducing symptomatology related to breast cancer, measured by scores of QLQ C30 and symptom score of QLQ BR23.</div></div><div><h3>Conclusion</h3><div>This study emphasizes the role of <em>Jatamansi Taila Shirodhara</em> therapy for mind and body relaxation in psychological distress seen in breast cancer especially, in TNBC patients.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 1","pages":"Article 101069"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Shirodhara and Abhyanga on serum cortisol in Anxiety – A case report","authors":"Ashu Sharma ,&nbsp;Megha Sugandh ,&nbsp;Atul Bhardwaj ,&nbsp;Arun Gupta","doi":"10.1016/j.jaim.2024.100948","DOIUrl":"10.1016/j.jaim.2024.100948","url":null,"abstract":"<div><div><em>Chittodvega</em>, classified as a <em>Mano-Vikara</em> (psychological disorder) in <em>Ayurveda</em>, can be correlated with general anxiety disorder. The disturbance of <em>Vata Dosha</em> plays a critical role in its manifestation. <em>Ayurvedic</em> treatments such as <em>Abhyanga</em> (oleation) and <em>Shirodhara</em> (dripping of medicated oil or other suitable liquid on forehead) are known to pacify <em>Vata</em>. <em>Abhyanga</em> helps to stabilize the body, while <em>Shirodhara</em> enhances concentration, promoting mental stability. Both procedures synergistically balance <em>Vata</em> <em>Dosha</em>, addressing the physiological and psychological aspects of <em>Chittodvega</em>.A 50-year-old male patient presented with complaints of anxiety at Ch. Brahm Prakash Ayurveda Charak Sansthan, New Delhi. He underwent a 14-day treatment regimen, including 7 days of hospitalization and 7 days of follow-up. The treatment involved Abhyanga(Oleation) with Til Taila (sesame oil) and <em>Shirodhara</em> with <em>Dashmool Siddha Ksheer</em> (herbal milk decoction), aimed at assessing their impact on serum cortisol levels. Both, morning and evening cortisol level of this patient was within the normal range before and after the treatment. This study was done only to check the effectiveness of <em>Abhyanga</em> and <em>Shirodhara</em> on serum cortisol level. Observable changes were found in serum cortisol along with a reduction in the patient's anxiety symptoms, demonstrating the efficacy of these <em>Ayurvedic</em> interventions in managing <em>Chittodvega</em>.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 1","pages":"Article 100948"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11773008/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coexisting pilonidal sinus and anal fistula: Successful management with minimal invasive Kshara Karma Technique and Ksharasutra therapy– A case report","authors":"P. Hemantha Kumar,&nbsp;Hetal Koriya","doi":"10.1016/j.jaim.2024.101082","DOIUrl":"10.1016/j.jaim.2024.101082","url":null,"abstract":"<div><div>Pilonidal sinus (PNS) is a nest of hair which typically presents as pits, pus discharge, and an abscess at the natal cleft region. In rare conditions where pilonidal abscess is not drained properly, it progresses posteriorly and reaches anal canal, eventually coexisting with anal fistula. Both are associated with a high recurrence rate despite surgical management. A 27 year old female patient presented with complaints of non-healing wound in the natal cleft region and pus discharge from wound for 2 months with a past surgical history for PNS. On local examination, a wound was seen at the natal cleft, secondary pit 3cm away with scar mark of the previous operation, and a digital rectal examination (DRE) revealed an internal opening at 6 o'clock position that was communicating with the previously operated PNS wound. The patient was diagnosed as a case of coexisting anal fistula and recurrent PNS. Patient was managed under spinal anaesthesia with interception of fistulous tract using <em>Ksharasutra</em> (Medicated alkaline thread), followed by Minimal Invasive <em>Kshara Karma</em> Technique (MIKKT) for PNS. <em>Ksharasutra</em> was sloughed out after the fifth week, and complete wound healing of PNS was achieved in six weeks. By interception of the fistulous tract, the length of the tract was reduced, which facilitated early wound healing and minimal scar mark formation. MIKKT also prevented bigger excision and wound formation, eventually reducing complete healing duration, and <em>Kshara</em>(a medicated alkali) applied caused chemical cauterization and hence prevented recurrence of pilonidal sinus.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 1","pages":"Article 101082"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quo vadis, Ayurveda?","authors":"R.S. Rajan","doi":"10.1016/j.jaim.2024.101042","DOIUrl":"10.1016/j.jaim.2024.101042","url":null,"abstract":"","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 1","pages":"Article 101042"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11782800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Ayurveda and Siddha interventions in the management of chronic lymphocytic leukemia: A case report","authors":"Abhay Kumar Prajapati ,&nbsp;Parvathy Venate ,&nbsp;T. Monika ,&nbsp;V.G. Huddar","doi":"10.1016/j.jaim.2024.101017","DOIUrl":"10.1016/j.jaim.2024.101017","url":null,"abstract":"<div><div>Chronic Lymphocytic Leukemia (CLL) is a hematological malignancy marked by the clonal proliferation of the mature, yet dysfunctional B lymphocytes in blood and its subsequent infiltration of the marrow, lymphoid tissues and spleen. The resultant immune dysfunction exposes the body to multiple infections and is a cause of major mortality. Here, we discuss the case of a 46-year-old male suffering from CLL who presented with long-standing episodes of low-grade fever, productive cough and throat irritation, lethargy and pedal edema. He was treatment-naïve at the time of presentation. He was treated in lines of Rajayakshma as per Ayurveda, and <em>Kuruthiputru</em> as per Siddha medicine. After three years of treatment with continued follow up till date, comprising of <em>Shamana</em> C<em>hikitsa</em> (Ayurveda and Siddha internal medications), <em>Sodhana</em> (bio purificatory methods)through <em>Mridu Virechana</em> (therapeutic purgation) <em>using Trivrut</em> A<em>valeha</em> 35g, Guduchi <em>Rasayana (Tinospora cordifolia)</em> and <em>Yashtimadhu Rasayana(Glycyrrhiza glabra),</em> patient reported reduction in frequency of infections, improved performance score with a mean reduction in TLC counts by 100 thousand/cu. mm in 10 months starting intervention. Presently the patient is stable with occasional episodes of dry cough and generalized weakness.</div><div>Integrated practices involving Ayurveda and Siddha medicines may be beneficial to patients suffering from CLL by reducing the episodes of infections, improving the quality of life while pacifying the deranged hematological parameters to certain extent.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 1","pages":"Article 101017"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142823819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A trans-disciplinary agro-ecology strategy to grow medicinal plants","authors":"Atul K. Gupta ,&nbsp;K Ravikumar ,&nbsp;Venu Gopal ,&nbsp;Noorunnisa Begum ,&nbsp;Tabassum ,&nbsp;Sathya Sangeetha ,&nbsp;Pavithra Narendran ,&nbsp;Darshan Shankar","doi":"10.1016/j.jaim.2024.100985","DOIUrl":"10.1016/j.jaim.2024.100985","url":null,"abstract":"<div><div>The scope of the emerging field of Ayurvedic-biology visualized thus far is confined to studies on dimensions pertaining to clinical and experimental pharmacology, basic <em>trans</em>-disciplinary science and drug design. However, given the multiple facets of classical Ayurveda knowledge system, its application in the field of organic agriculture perhaps also needs to be urgently explored. The urgency is due to the growing public acceptance of Ayurveda as a preferred clinical choice for well-being and disease management. The turnover of the sector across manufacturing and health services is estimated to be around Rs.1,00,000 crores per annum. Medicinal plants today and in the coming decade will therefore be required in large volumes and given that their applications are solely for enhancing health of humans, livestock (Pashu Ayurveda) and crops (Vriksh Ayurveda), it is imperative that they be cultivated in an organic manner employing the fusion of best available inter-cultural knowledge.</div><div>The Ayurvedic subjects relevant for organic agriculture are <em>Desh vichar, Dravya guna</em> Shastra and <em>Vriksh Ayurveda</em>. From the perspective of modern biology subjects like soil micro biome, genetics, plant physiology and the natural geographical distribution of species are relevant.</div><div>It must be stated at the very outset that this article is largely theoretical. While experiments in <em>Vriksh Ayurveda</em> have been attempted on a small scale, the fusion of Ayurveda and biology for improving organic agriculture of medicinal plants has thus far not been systematically explored.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 1","pages":"Article 100985"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11741952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142894646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}