Journal of Ayurveda and Integrative Medicine最新文献

{"title":"The art and science of research methodology, biostatistics, manuscript writing, and publication ethics: An invigorating training for improving research aptitudes in southern Indian biomedical institutions","authors":"Pitchai Balakumar,&nbsp;Shubhada Nagarkar,&nbsp;Gangaboriah Bilagumba,&nbsp;Ramesh Alluri,&nbsp;Gowraganahalli Jagadeesh","doi":"10.1016/j.jaim.2024.100996","DOIUrl":"10.1016/j.jaim.2024.100996","url":null,"abstract":"<div><p>The basic concepts of research are learned through systematic literature searches which form the basis of a research statement and research topic. Then the research question, hypothesis, aim, and objectives, as well as the experimental design, are developed. Given the context provided, the primary focus is on the importance of adequately training postgraduates and young research investigators in research methodology and project development. It is evident that there is a lack of proper training in these areas, and the rapid expansion of colleges in India exacerbates this issue. To address this, research students must receive comprehensive instruction in scientific research methodology, experimental design, statistics, scientific writing, publishing, and research ethics. Our team has been conducting workshops and symposia for more than two decades to improve the current teaching methods in these areas. Most recently, we organized a series of national and international workshops and seminars in multiple states across India to fortify the core concepts of scientific research for students and faculty members. This report highlights the key aspects of these workshops and the positive outcomes experienced by participants.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947624001116/pdfft?md5=26ecfd3dbc81d2ccf0bd2c61a8b05b7c&pid=1-s2.0-S0975947624001116-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141468119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectivity of oral ginger supplementation for chemotherapy induced nausea and vomiting (CINV) in children: A systematic review of clinical trials","authors":"","doi":"10.1016/j.jaim.2024.100957","DOIUrl":"10.1016/j.jaim.2024.100957","url":null,"abstract":"<div><p>Chemotherapy-induced nausea and vomiting (CINV) affects over 50% of pediatric patients undergoing chemotherapy, a higher proportion than in adults. CINV often occurs despite adequate antiemetic prophylaxis, hampering patients' willingness to continue the chemotherapy regimen. As an ayurvedic medicine, ginger (<em>Zingiber officinale</em>) has an antiemetic effect by inhibiting serotonin in gastrointestinal nerves and as an NK1 antagonist. Therefore, we aimed to review oral ginger supplementation in children with CINV systematically.</p><p>Systematic searching was performed in June 2023 from Pubmed, Embase, CINAHL, Cochrane, and hand searching. The search consisted of PICO “children chemotherapy”, “ginger”, and “CINV incidence”. We limited the search to only human studies. Studies that meet inclusion and exclusion criteria were included for analysis.</p><p>Out of 116 studies found with our selection criteria, four were compatible with inclusion and exclusion criteria. Two studies had a small Risk of Bias (RoB), while the others had a high RoB. All studies statistically significantly reduced acute and delayed CINV with the number needed to treat (NNT) 2–4. No adverse effects were reported. However, these studies still had high heterogeneity based on cancer treatment, chemotherapy regimen, ginger dosing, and ginger processing.</p><p>Ginger has the potential to reduce both the acute and delayed phases of CINV in children. Additional research employing standardized methodologies is recommended to validate this effect.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S097594762400072X/pdfft?md5=10e0d67dcacf5bb48aa02f6bc9a81354&pid=1-s2.0-S097594762400072X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142020431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to editor - Assessing the efficacy of meditation in the management of infertility","authors":"","doi":"10.1016/j.jaim.2024.100965","DOIUrl":"10.1016/j.jaim.2024.100965","url":null,"abstract":"","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947624000809/pdfft?md5=d136795fb32d3cbb47aabc6d417cfd01&pid=1-s2.0-S0975947624000809-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141320865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ayurveda Management of IUGR due to single umbilical artery: A case report","authors":"","doi":"10.1016/j.jaim.2024.100974","DOIUrl":"10.1016/j.jaim.2024.100974","url":null,"abstract":"<div><p>IUGR is defined as a rate of fetal growth that is less than normal for the expected growth potential of a specific infant. Fetuses with isolated single umbilical artery are at higher risk of prematurity, IUGR(Intra uterine growth restriction), and intrauterine death. Ayurveda provides a holistic approach towards <em>garbhini paricharya</em> (antenatal care). <em>Nabhinadi</em> (umbilical cord) nourishes the fetus, and abnormalities result in <em>garbhashosha</em>. This is a case report of IUGR associated with a single umbilical artery with no other abnormalities. The obstetric scan revealed decreased abdominal circumference and falling growth parameters. Ayurvedic medicines with <em>brimhana, balya, prajasthapana</em> actions were given. The outcome was a full-term baby of birth weight 2.5kg through vaginal delivery.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947624000895/pdfft?md5=ee6dded0e5b1252e8b58d4f9e7b4f158&pid=1-s2.0-S0975947624000895-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141878747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antidiabetic and antioxidant properties of Boswellia sacra oleo-gum in streptozotocin-induced diabetic rats","authors":"","doi":"10.1016/j.jaim.2024.101014","DOIUrl":"10.1016/j.jaim.2024.101014","url":null,"abstract":"<div><h3>Background</h3><p>Diabetes is a metabolic disorder requiring the administration of insulin or other oral hypoglycemic medicines. Although metformin is a popular prescription for type 2 diabetes, long-term use of chemotherapy-based diabetes medications can be hazardous. As a result, novel plant medicines with a high concentration of bioactive molecules, no harmful side effects, and potent pharmacological effects must be found. Edible Boswellia sacra (<em>B. sacra</em>) Flueck oleo-gum resin is widely utilized to treat many clinical diseases in traditional Arab, Chinese, African, and Ayurvedic medicine.</p></div><div><h3>Objective</h3><p>The goal of this study was to examine the possible therapeutic benefits of several <em>B. sacra</em> oleo-gum resin extracts on rat streptozotocin (STZ)-induced hyperglycemia (Type II).</p></div><div><h3>Materials and methods</h3><p>For 29 days, hyperglycemic rats are given either metformin (the reference drug; 250 mg/kg body weight per day) or several <em>B. sacra</em> extracts (ethanol, methanol, hydrodistilled, ethyl acetate, and acetone extracts) at doses of 200 or 400 mg/kg/day. Blood glucose levels and body weights were measured before the initiation and at 7, 11, 16, 22, and 29 days after oral treatment. Furthermore, an oral glucose tolerance test (OGTT) was carried out. At the end of the study, the rats were euthanized, and blood samples were obtained to evaluate cytokines (interleukin (IL-)2 and IL-8), reduced glutathione (GSH), superoxide dismutase (SOD), and serum insulin levels. The pancreas and liver tissues were rapidly excised, washed, fixed, and kept in a 10% formalin buffer for histological examination.</p></div><div><h3>Results</h3><p><em>B.</em> sacra's ethanolic extract had the greatest concentration of total pentacyclic triterpenic acid (PTA) (391.52 mg/g) in comparison to the other extracts. The lower dose of <em>B. sacra</em> ethanol extract, 200 mg/kg/day, reduces blood glucose levels more efficiently than the higher dose of 400 mg/kg/day. In a 180-min OGTT, diabetic rats given ethanol extract (200 mg/kg) performed no better than control rats and even outperformed those given the reference medication metformin. Additionally, ethanol extract (200 mg/kg)- or metformin-treated diabetic rats gained weight. This was associated with a significant (<em>p</em> &lt; 0.05) decrease in serum levels of IL-2 and IL-8, a reduction in oxidative stress as evidenced by a significant (<em>p</em> &lt; 0.05) increase in SOD and GSH compared to the untreated diabetic group, and a significant (<em>p</em> &lt; 0.05) increase in serum insulin levels compared to normal plasma rat levels. These discoveries, which were eventually confirmed by histochemical assays, indicated that the ethanol extract of <em>B. sacra</em> greatly enhanced the cellular architecture of pancreatic and liver cells.</p></div><div><h3>Conclusion</h3><p>The present investigation indicates that the ethanol extract of <em>B. sacra</em> o","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947624001293/pdfft?md5=4f32a076991ec11158a55d3df0efb7ca&pid=1-s2.0-S0975947624001293-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142011715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green gram soup and barley porridge as dietary interventions for management of premenstrual syndrome in adolescent girl: A case report","authors":"Ankita Abhijeet Shirkande ,&nbsp;Madhuri Pawar ,&nbsp;Abhijeet Sarjerao Shirkande ,&nbsp;Gunvant Yeola","doi":"10.1016/j.jaim.2024.100912","DOIUrl":"https://doi.org/10.1016/j.jaim.2024.100912","url":null,"abstract":"<div><p>Women suffer from various conditions related to menstrual cycle due to changing lifestyle, bad food habits, physical and mental stress. Pre Menstrual Syndrome (PMS) is a combination of physical and emotional symptoms that many women get one or two weeks before the start of their menstrual period. In the present study, 14 years old female patient having symptoms-lower abdominal pain, backache, breast tenderness, constipation, pimples, tiredness and unexplained anger typically in luteal phase from last 4 months, was diagnosed with mild to moderate symptoms of PMS. After proper analysis, she was suggested to consume light to digest dietary articles advised in classical texts for minimizing specific symptoms during menstruation.Thus Green gram Soup and Barley porridge was prescribed to her as lunch and dinner respectively for first three days of menstruation cycle for continuous 6 cycles. It is observed that consumption of these dietary products during the menstruation time period assisted to minimize the symptoms of PMS. This illustrates that there is a wide scope to explore the ayurvedic dietary regimen recommended during menstruation which can be used more rationally to suit menstrual disorders.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947624000275/pdfft?md5=cce0a490ee4144c2c60ebca954074a72&pid=1-s2.0-S0975947624000275-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141444125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diffuse systemic sclerosis managed with ayurvedic treatment modalities - A case report.","authors":"Ranjani Karthik Pandit","doi":"10.1016/j.jaim.2023.100883","DOIUrl":"https://doi.org/10.1016/j.jaim.2023.100883","url":null,"abstract":"<p><p>Diffuse systemic sclerosis or scleroderma is a chronic connective tissue disorder involving many systems and visceral organs. The association of interstitial lung disease carries high mortality risk. This is a case report of a patient aged 25-years, who was diagnosed as diffuse systemic sclerosis, a disease complex along with Interstitial Lung Disease (ILD), sclerodactyly. She also presented with digital ulcers and calcium deposits in the ulcers. The symptomatology was understood by analysing the dosha predominance and the composition of the different qualities of each dosha in the patient. This complicated case with a bad prognosis was managed with Ayurvedic treatment procedures and medicines. Matrabasti (medicated enema) with mahamasha taila and dhanvantara taila was given. yogabasti with dashamoola ksheera paka, dhanvantara taila and madhu (decoctive enema), along with other palliative medicines like rasna yoga raja, Yogendra rasa, vasakasava, drakshadi paka, kaishora guggulu, raktapachakaghana vati and Mahatiktaka ghrita were given to the patient. After 1-1.2 years of continuous treatments, patient started showing gradual changes in her health condition. Relief from joint pains, intake of normal food, weight gain, re-establishment of menstruation, healing of ulcers was some of the changes seen in the patient. This case report summaries the effective management of diffuse systemic sclerosis after deducing the complex disease structure to dosa and guna involved and treated by adopting ayurvedic medicine and treatment procedures.</p>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140957567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An immediate pain relief with Agnikarma therapy for acute episode of migraine headache—a case report","authors":"Praveen Balakrishnan,&nbsp;Emy S. Surendran,&nbsp;Lisha S. Raj","doi":"10.1016/j.jaim.2024.100953","DOIUrl":"10.1016/j.jaim.2024.100953","url":null,"abstract":"<div><p>A 58-year-old non-diabetic, non-hypertensive, non-dyslipidemic, euthyroid lady with a known case of migraine for last 10 years approached our hospital complaining of a severe right-sided throbbing headache in the temple area and behind the right ear for three days. She approached our hospital as she did not get any relief from painkillers. An intensity of 10 was recorded on Visual Analogue Scale (VAS) and 8 on the Global Assessment of Migraine Severity (GAMS) Scale. The case was diagnosed to be <em>vatika shirashula</em> on <em>ardhavabhedaka</em>, with no <em>pitta-rakta</em> association. She was posted for <em>Agnikarma</em> therapy [AGT]. Immediately, within 2 min of application of AGT on her right temple, her intense pain reduced, and within 5 min she had no pain [zero on VAS scale and one on GAMS scale]. <em>Samyak mamsa dagdha lakshana</em> was achieved. AGT was tolerable and did not produce any major discomforts. No adverse effects were reported. Patient experienced a mild burning sensation over the AGT, and the blackish discoloration due to AGT faded off within 41 days. AGT could be used as a potent, cheap, fast-acting, adverse effect free emergency treatment for acute attacks of migraine headache.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947624000688/pdfft?md5=a385ee42b7442561e0a22ae9b8ed52ef&pid=1-s2.0-S0975947624000688-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141317443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic subdural hematoma treated with homeopathic medicine Hamamelis virginica: A case report","authors":"Baidurjya Bhattacharjee ,&nbsp;Abhijit Dutta","doi":"10.1016/j.jaim.2024.100928","DOIUrl":"https://doi.org/10.1016/j.jaim.2024.100928","url":null,"abstract":"<div><p>Chronic Subdural Hematoma is a prevalent neurosurgical disorder associated with old age, often resulting from trauma. The condition has limited scope for conservative management, and invasive techniques are frequently used as preferred treatment. Complications often arise due to comorbidities associated with old age. This case details the treatment of the condition in a 71-year-old patient who presented with seizures, hemiparesis, tremor, and disorientation. The patient had a history of a fall a few weeks prior. Initially, the condition was managed through surgery, but recurrence occurred, accompanied by concurrent neurological signs. The patient was subsequently treated with <em>Hamamelis virginica</em> 200CH through homeopathic approach. Following this treatment, the patient returned to his previous state within seven days. No recurrence was observed during the three-month follow-up. This case underscores a positive role of homeopathic medicines in managing neurosurgical conditions such as subdural hematoma. The positive outcomes of this study provide preliminary evidence that may eventually contribute to the design of appropriate clinical trials.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947624000433/pdfft?md5=d9ac87ad0c9807d699345d779082149d&pid=1-s2.0-S0975947624000433-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141089715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing effects of Cannabis on various neuropathologies: A systematic review","authors":"Suhrud Pathak ,&nbsp;Jeyaram Bharathi Jeyabalan ,&nbsp;Keyi Liu ,&nbsp;Preston Cook ,&nbsp;Bennett Lange ,&nbsp;Shannon Kim ,&nbsp;Rishi Nadar ,&nbsp;Kiersten Ward ,&nbsp;Courtney S. Watts Alexander ,&nbsp;Ashwani Kumar ,&nbsp;Kamal Dua ,&nbsp;Timothy Moore ,&nbsp;Jeyabalan Govindasamy ,&nbsp;Muralikrishnan Dhanasekaran","doi":"10.1016/j.jaim.2024.100911","DOIUrl":"10.1016/j.jaim.2024.100911","url":null,"abstract":"<div><p>Natural bioactives possess a wide range of chemical structures that can exert a plethora of pharmacological and toxicological actions, resulting in neuroprotection or neurotoxicity. These pharmacodynamic properties can positively or negatively impact human and animal global healthcare. Remarkably, Ayurvedic botanical Cannabis has been used worldwide by different ethnicities and religions for spiritual, commercial, recreational, nutraceutical, cosmeceutical, and medicinal purposes for centuries. Cannabis-based congeners have been approved by the United States of America's (USA) Food &amp; Drug Administration (FDA) and other global law agencies for various therapeutic purposes. Surprisingly, the strict laws associated with possessing cannabis products have been mitigated in multiple states in the USA and across the globe for recreational use. This has consequently led to a radical escalation of exposure to cannabis-related substances of abuse. However, there is a lacuna in the literature on the acute and chronic effects of Cannabis and its congeners on various neuropathologies. Moreover, in the post-COVID era, there has been a drastic increase in the incidence and prevalence of numerous neuropathologies, leading to increased morbidity and mortality. There is an impending necessity for a safe, economically viable, multipotent, natural bioactive to prevent and treat various neuropathologies. The ayurvedic herb, Cannabis is one of the oldest botanicals known to humans and has been widely used. However, the comprehensive effect of Cannabis on various neuropathologies is not well established. Hence, this review presents effects of Cannabis on various neuropathologies.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947624000263/pdfft?md5=2661edfe0a490051f08622c74a74032d&pid=1-s2.0-S0975947624000263-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141320864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}