Journal of Ayurveda and Integrative Medicine最新文献

{"title":"Malondialdehyde and TNF-α lowering effects of purified gambier (Uncaria gambir Roxb.) in diabetic rats","authors":"Armenia Armenia ,&nbsp;Elsa Badriyya ,&nbsp;Sri Rahmita ,&nbsp;Fitri Rachmaini ,&nbsp;Rahmad Abdillah","doi":"10.1016/j.jaim.2023.100855","DOIUrl":"10.1016/j.jaim.2023.100855","url":null,"abstract":"<div><h3>Background</h3><p>Malondialdehyde (MDA) is one of a dominat marker in oxidative stress condition, and when inflammation occurred tumor necrosis factor- α (TNF-α<strong>)</strong> played a significant influence in the propagation this process. Purified gambier (<em>Uncaria gambier</em> Roxb.) contained 90% catechin which is proven to have antioxidant activity and may prevent unwanted inflammatory responses during diabetic state. <strong>Objective:</strong> The objective of this research was to assess how purified gambier affected plasma MDA and TNF- α levels in alloxan-induced diabetic rats. <strong>Material and methods:</strong> In this study, 35 rats were used. Alloxan 120 mg/kg BW intraperitoneal injection was administered to induce diabetes conditions in rats. All animals were divided into 5 groups, diabetic control group treated with vehicle, positive control group treated with glibenclamide dose 0.45 mg/kg BW), and treatment groups treated with purified gambier dose of 2.5; 5 and 10 mg/kg BW. All animals were treated respectively for 14 days. Plasma MDA and TNF- α levels were measured on day 3, and 14. <strong>Results:</strong> Two-way ANOVA was applied to analyze all of the data, these findings suggested that purified gambier has antioxidant-related anti-inflammation actions. possesses blood sugar-lowering activity (p&lt;0.05). The plasma MDA and TNF- α level of treatment group were significantly reduced (p&lt;0.05) compared to diabetes control group. <strong>Conclusion:</strong> These results depicted that at doses of 2.5–10 mg/kg BW, purified gambier has antioxidant-associated anti-inflammation effects when given for 14 days on diabetic rat model by reducing plasma levels MDA and TNF-α.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947623001729/pdfft?md5=7cf7f312560853d7890589216d62620f&pid=1-s2.0-S0975947623001729-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139546130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ayurveda management of a patient having bronchial asthma and hemorrhoids- A case report","authors":"Punam Khobarkar ,&nbsp;Amit Nakanekar","doi":"10.1016/j.jaim.2023.100863","DOIUrl":"https://doi.org/10.1016/j.jaim.2023.100863","url":null,"abstract":"<div><p><em>Ayurveda</em> is a holistic science that treats root cause of diseases. One disease can become a causative factor for another disease. This concept is fundamentally described as <em>Nidanarthakar Vyadhi</em> in <em>Ayurveda</em>. In the same way, treating causative diseases is helpful in managing another diseases. However, many published clinical trials on <em>Ayurveda</em> management of Bronchial asthma and Hemorrhoids exist. There is a dearth of published case reports or clinical trials showing an association between <em>Arsha</em> (hemorrhoids) and <em>Shwasa</em> (bronchial asthma). This case report gives important viewpoints about the role of hemorrhoids and its treatment in pathogenesis and treatment of bronchial asthma.</p><p>This case report of a 38-year-old female patient known case of bronchial asthma who came to the OPD of <em>Kayachikitsa</em> Government <em>Ayurved</em> College and Hospital, Nagpur with complaints of cough with sputum, breathlessness, chest pain (on/off) for three years. The severity of these symptoms increased for three months. The patient was treated with conventional <em>Shwasghna Chikitsa</em> (treatment of bronchial asthma) for five days, but the response was unsatisfactory. After five days of <em>Shwasghna</em> treatment, the patient gave a history of hemorrhoids. Considering <em>Nidanarthakar Roga</em> (one disease can cause of another disease), treatment was planned. The treatment principle is the treatment of causative disease (<em>Arsha</em>). Hence, <em>Arshoghna</em> treatment was added. Significant increases in peak expiratory flow rate (PEFR), Sustained minimal inspiration (SMI), and Modified Medical Research Council Dyspnoea scale (mMRC) were observed. The respiratory rate was also reduced from 28/min to 18/min. Improvement in the subjective and objective parameters of the patient was observed.</p><p>The inclusion of <em>Arsha</em> treatment can be helpful in the management of <em>Tamakshwas</em> (Bronchial Asthma). The need for further research in this direction is warranted.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947623001808/pdfft?md5=d2293a88acc0c43b9be3b29f89b52c08&pid=1-s2.0-S0975947623001808-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139744404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrative oncology in Cancer Care Continuum","authors":"Manohar S. Gundeti,&nbsp;Julia T. Arnold","doi":"10.1016/j.jaim.2024.100907","DOIUrl":"https://doi.org/10.1016/j.jaim.2024.100907","url":null,"abstract":"","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947624000226/pdfft?md5=d0c47f56c50b3f2a71653e430648c8ca&pid=1-s2.0-S0975947624000226-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139986979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrative management of insomnia during cancer chemotherapy: A case report","authors":"P. Arathi ,&nbsp;K. Sreejith ,&nbsp;K. Pavithran ,&nbsp;Devipriya Soman","doi":"10.1016/j.jaim.2024.100899","DOIUrl":"https://doi.org/10.1016/j.jaim.2024.100899","url":null,"abstract":"<div><h3>Introduction</h3><p>Insomnia is common among cancer patients, affecting about 50% undergoing cancer treatment. Insomnia can be due to various reasons, such as physical-pain, psychological-distress and medication side-effects. Insomnia has significant impact on quality of life of cancer patients. Even-though managed with hypnotics and antipsychotic drugs, they cause dependency with various short-term and long-term complications. Presenting a case throwing light on <em>Ayurveda</em> topical intervention as add-on to standard-of-care in insomnia during cancer chemotherapy.</p></div><div><h3>Method</h3><p>A 51-year-old female patient with breast-cancer with extensive necrosis extending to subcutaneous areas was due for second cycle chemotherapy and was diagnosed with moderate-insomnia with a score of 21 as per Insomnia Severity Index in the Out-Patient-Department. Quality of sleep was assessed using Pittsburgh-Sleep-Quality-Index. Treated for 14 days during the break between cycle two and cycle three with <em>Shirothalam</em> (applied on the vertex) using <em>Kachuradi Churnam</em> with <em>Kshirabala 101</em> and <em>Padabhyangam</em> (foot massage) using <em>Kshirabala thailam</em> as add-on to Tab Zolpidem5mg. Assessment was conducted on baseline and after 14 days of intervention.</p></div><div><h3>Results</h3><p>Assessment for insomnia before and after intervention was conducted with Insomnia-Severity-Index. The score improved from 21 to 2. Quality of sleep before and after intervention was assessed using global PSQI. It improved from 20 to 8.</p></div><div><h3>Discussion</h3><p>In <em>Ayurveda</em>, <em>Nidranasam</em> (loss of sleep) results from aggravation of <em>Vata-Pitta</em> (body humors responsible for movement and cognition and digestion, metabolism and heat of body<em>)</em>, depletion of <em>Kapha</em> (body humor responsible for structural cohesion of body), derangement of <em>Manasika-Dosa</em> (mental constituents) and other diseases. All these etiological factors are attributed by <em>Tikshna(sharp)- Uṣhna(hot potency) and Ruksha(dry)</em> chemotherapy regimens. <em>Vata-Pitta-hara</em> (normalising <em>Vata and Pitta</em>) and <em>Indriyaprasadaka</em> (clearing senses) action of medicines used could induce sleep and effectively improve quality of sleep.</p></div><div><h3>Conclusion</h3><p>Integrative-intervention was found to be beneficial in improving insomnia and quality of sleep without any reported complications or dependency in this case. After 14 days of ayurvedic intervention, the patient could get sleep even without taking zolpidem 5mg and external therapies. Same protocol could be considered for generalization so that it could modify or reduce usage of hypnotics and antipsychotic-drugs.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947624000147/pdfft?md5=ed2185076c10aab27515e01d34785b44&pid=1-s2.0-S0975947624000147-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139907366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation of family adoption program using five-pronged strategy of integrated holistic health team: A way forward","authors":"Abhay Mudey,&nbsp;Juhi Raut","doi":"10.1016/j.jaim.2024.100888","DOIUrl":"10.1016/j.jaim.2024.100888","url":null,"abstract":"<div><p>About 65.5 % of the Indians live in rural areas while availability of healthcare is biased towards urban setups. Medicine in undergraduates is taught in ivory towers of medical colleges, a paradigm shift in teaching bedside medicine from these ivory towers to community level is required. Hence a new competency-based medical education for undergraduate course was adopted with family adoption program as a vital component, which provides an opportunity for undergraduates to get sensitised to problems and social dynamics at grass root level. We propose an integrated holistic health team model to implement family adoption program so as to address needs of community and build consensus amongst graduate students from various health disciplines to work in integrated team approach and result in enhanced learning. A five pronged strategy is implemented by forming an integrated team comprising of students from medical, aental, ayurveda, and physiotherapy &amp; nursing streams. The institutions that have undergraduate program for any two to five of these disciplines can adopt proposed approach. Expected outcomes of utilising this model is to create holistic health team thereby inculcating in budding graduates team spirit, mutual cooperation &amp; respect for other disciplines of health sciences and thereby holistic healthcare to community.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947624000032/pdfft?md5=ccbae828ff7c5c29efd863fd97a14dd0&pid=1-s2.0-S0975947624000032-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139697524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A scoping review on ‘Maharishi Amrit Kalash’, an ayurveda formulation for cancer prevention and management","authors":"Rini Vohra ,&nbsp;Radha Singh ,&nbsp;Richa Shrivastava","doi":"10.1016/j.jaim.2023.100866","DOIUrl":"https://doi.org/10.1016/j.jaim.2023.100866","url":null,"abstract":"<div><h3>Background</h3><p>Cancer is one of the leading causes of morbidity and mortality. Current treatments include chemotherapy, radiotherapy, etc., are known to be associated with several side effects. Hence, complementary and alternative medicine is growing in acceptance around the world, particularly Ayurvedic formulations. MAK is one of the most scientifically acclaimed formulations with potential anti-neoplastic and chemoprotective properties.</p></div><div><h3>Objective</h3><p>To study literature available on the anti-neoplastic and chemoprotective effects of MAK.</p></div><div><h3>Material and methods</h3><p>A systematic literature review was conducted using multiple web-based sources: Google Scholar (185), PubMed (33), DHARA (49), AYUSH research portal (2), EBSCO (66), and CTRI (1) for all studies published before February 2021 using keywords: <em>Maharishi Amrit Kalash, Amrit Kalash, Amrit, MAK-4, MAK-5, MAK-7,</em> and others. A manual search was conducted on the reference list of all included articles to identify additional studies. Studies with cancer and/or chemotoxicity outcomes were selected manually. Evidence from both preclinical and clinical level studies have been included in the current review.</p></div><div><h3>Results</h3><p>Out of total 79 studies on applications of MAK, 13 studies were found to state its anti-neoplastic and chemoprotective effects. The studies showed role of MAK in initiation of neoplastic transformation of cancer cells (1), carcinogenesis inhibition (4), metastases inhibition/reduction (1), cancer growth inhibition (4), induction of morphological and biochemical differentiation of cancer cells (3), and reduction in chemotoxicity (4). In studies with controlled clinical trial design (3), MAK use among patients with cancer showed a significant reduction in anorexia, vomiting, and other side effects associated with chemotherapy. A general improvement in quality-of-life scores (Karnofsky Performance Status) and well-being was also observed among patients using MAK.</p></div><div><h3>Conclusion</h3><p>Evidence from pre-clinical studies show promising results for use of MAK as an anti-cancer and a chemoprotective agent. More clinical studies are needed to assess the impact of MAK use for tumour regression among patients with cancer. Current scoping review provides sufficient evidence on MAK to be considered for further exploration for its anti-cancer/chemoprotective effects in bigger randomized clinical trials.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947623001833/pdfft?md5=59ef39a90e4105ea12983a4d5f1e1e68&pid=1-s2.0-S0975947623001833-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139399441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of adjuvant yoga therapy for asthma control: A randomized controlled trial","authors":"Anshu Yadav ,&nbsp;Girish Sindhwani ,&nbsp;Ranjeeta Kumari ,&nbsp;Arun Goel ,&nbsp;Khushboo Bisht","doi":"10.1016/j.jaim.2023.100847","DOIUrl":"10.1016/j.jaim.2023.100847","url":null,"abstract":"<div><h3>Background</h3><p>Asthma is a chronic respiratory disease with symptoms of attacks of wheezing, shortness of breath, &amp; tightness in the chest. Even with pre-existing treatment exacerbations go uncontrolled.</p></div><div><h3>Objective</h3><p>This study compared asthma control in yoga intervention versus non-yoga intervention group using Asthma Control Test.</p></div><div><h3>Methods</h3><p>In this randomized controlled trial, participants were allocated into two groups in 1:1 ratio - yoga intervention versus non-yoga intervention. Only outcome assessor was blinded. Sample size of 200 was calculated. Individuals between 18 and 60 years of age, diagnosed with mild to moderate asthma with no exacerbation in past one month were screened and enrolled. Per-protocol analysis was done to assess the outcomes of Asthma Control Test and expenditure.(CTRI/2020/02/023534)</p></div><div><h3>Results</h3><p>A total of 192 participants enrolled, 165 completed this study who were considered for final analysis. A significant difference (p &lt; 0.001) was found between yoga and non-yoga exercise group at 13 weeks. Expenses were more in non-yoga exercise group.</p></div><div><h3>Conclusion</h3><p>Our findings confirm that yoga exercise with routine medical care reduces exacerbations and improves asthma control.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S097594762300164X/pdfft?md5=8d811e36bd23fcb1cc7bbe65c7506310&pid=1-s2.0-S097594762300164X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139491207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health benefits of ghee: Review of Ayurveda and modern science perspectives","authors":"Deepshikha Kataria ,&nbsp;Gurmeet Singh","doi":"10.1016/j.jaim.2023.100819","DOIUrl":"https://doi.org/10.1016/j.jaim.2023.100819","url":null,"abstract":"<div><p>The scientific view on dairy fats is undergoing a change. While at one time they were associated with negative health effects, recent scientific research has provided new insights into the functional benefits of dairy fats and their fatty acids. This changing scientific view on dairy fats is also resulting in a scientific interest in Ghee, the clarified butter obtained from milk. Ghee, besides being a traditional milk product of cultural importance in India and finding extensive use in its cuisines, is also one of the most important ingredients of the <em>materia medica</em> of Ayurveda, the traditional system of medicine that originated in India. While modern scientific literature has limited studies on functional benefits of ghee, Ayurveda literature extensively catalogues the therapeutic potential of ghee and details different types of ghee based on source of milk, manufacturing method, maturation and physical phase. This work reviewed the Ayurveda literature on health benefits of ghee and examined the complementarity and gaps between Ayurveda literature and modern scientific literature to identify research questions and hypotheses for further exploring the therapeutic potential of ghee. The Ayurveda literature review involved curation of references to ghee in eleven important Ayurvedic texts spanning over 3000 years. 4000 references to milk and milk products were curated from these texts, of which 2913 mentions were in the context of therapeutic benefits of milk products. Of these, ghee had 774 mentions, the highest amongst milk-based products. These mentions were grouped into 15 benefit clusters. A review of ghee in modern literature published between 1990 and 2023 was also conducted. A comparison of this with the Ayurveda literature showed that there were major differences in the focus areas of health between the two. While recent research primarily focused on ghee's connection with cardiovascular health, wound healing and skin health, Ayurveda prioritized cognitive benefits, gastrointestinal health, and nourishing. These later areas are of growing importance to human health as global population ages, and chronic and brain related diseases start dominating public health concerns. As scientists search for solutions to these, ghee, its usage and formulations in Ayurveda and the detailed associations between ghee's animal source, processing, maturation, phases and health benefits, may have scientific insights to offer that can guide future research.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947623001365/pdfft?md5=cb2a607878ce8fe7a0b623a5983fd32c&pid=1-s2.0-S0975947623001365-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139099845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"'Vidangadi Lauha' for obese type 2 diabetes mellitus patients - An open-label randomized controlled clinical trial","authors":"Punam Khobarkar ,&nbsp;Jayant Gulhane ,&nbsp;Amit Nakanekar","doi":"10.1016/j.jaim.2023.100878","DOIUrl":"https://doi.org/10.1016/j.jaim.2023.100878","url":null,"abstract":"<div><h3>Background</h3><p>Type 2 diabetes mellitus in obese persons is becoming alarming due to the increasing prevalence of its microvascular and macrovascular complications. Multi-targeted treatment can be considered better than single-targeted treatment because of the multiple pathways involved in the pathogenesis of diabetes and its complications.</p></div><div><h3>Objective</h3><p>The study aimed to evaluate the efficacy of ‘<em>Vidangadi Lauha'</em> (<em>VL</em>) (an <em>Ayurveda</em> formulation) compared with Metformin for obese type II diabetes mellitus.</p></div><div><h3>Methodology</h3><p>This is an open-label randomized controlled clinical study.Participants were divided into two groups. The trial Group received <em>VL</em> 5 gm BID, and the control group received tablet metformin (MT) 500 mg BID for three months.</p></div><div><h3>Results</h3><p><em>VL</em> showed reduction in HbA1c from 8.048(0.95) to 7.14(0.73), (CI, 0.7810 to 1.035; p &lt; 0.0001) while MT showed reduction in HbA1C from 8.3(0.99) to7.18(0.67), (CI, 0.9220 to 1.305; p &lt; 0.0001). <em>VL</em> showed improvement in the Quality of life instrument for the Indian Diabetes questionnaire(QOLID) score from 113.87(11.36) to 136.47(8.703) (CI, −25.68 to −19.52; p &lt; 0.0001) as compared to MT 128.57(7.9) to 102.32(7.9), (CI, 23.19 to 29.39; p &lt; 0.0001) <em>VL</em> showed reduction in bowel symptom questionnaire 30.275(8.077) to 13.2(1.265), (CI, 14.60–19.51; p &lt; 0.0001) as compared to MT from 23.85(7.530) to 38.25(6.332), (CI, −15.99 to −12.80; p &lt; 0.0001).</p></div><div><h3>Conclusion</h3><p>Both treatments were equally effective in reducing blood sugar fasting (F), post-meal (PM) glycated hemoglobin (HbA1C), and body mass index (BMI). <em>VL</em> is more effective than MT in reducing <em>Ayurvedic</em> symptoms, waist-hip ratio, cholesterol, quality of life, and bowel symptom questionnaire score.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S097594762300195X/pdfft?md5=ec32b309f16b76abf777279946e55125&pid=1-s2.0-S097594762300195X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139549255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrative medicine for musculoskeletal pains - A proposed model based on clinical experience","authors":"Kiran Shete,&nbsp;Shraddha Potdar","doi":"10.1016/j.jaim.2023.100858","DOIUrl":"https://doi.org/10.1016/j.jaim.2023.100858","url":null,"abstract":"<div><p>With an increasing number of chronic diseases and related disabilities, modern medicine is falling short of offering definitive, cost-effective, long-term solutions. As we realize contemporary medicine's limitations and side effects, we are gravitating towards whole-person care. Taking learnings from integrative medicine treatment of musculoskeletal pains, I comprehended that a paradigm shift is needed in thinking about etiopathogenesis and diagnosing disease. Different healing possibilities can be identified in humans if we shift our focus from reductionist science to whole-person care. Each health condition is an outcome of disturbed homeostasis involving multiple body systems. Based on homeostatic balancing principles and clinical experience, five interrelated and interdependent pathways are discussed. Based on these pathways, a working model of integrative medicine is presented. It can act as a template for medical practitioners to start integrative medicine practice for the benefit of patients. To make integrative medicine mainstream, there is a need to standardize care, frame regulations, train and educate the practitioners. At the same, it shall be put to rigorous scientific experimentation, research, and scrutiny.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947623001754/pdfft?md5=814ba37caa432f3d9eacda0cd576d2bf&pid=1-s2.0-S0975947623001754-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139433822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}