Journal of Ayurveda and Integrative Medicine最新文献

{"title":"Conference report: Dhara - Vision Ayurveda 2047","authors":"Sanchita Sangle,&nbsp;Prajakta Pakhale,&nbsp;Madhura Joshi,&nbsp;Akash Saggam","doi":"10.1016/j.jaim.2023.100848","DOIUrl":"https://doi.org/10.1016/j.jaim.2023.100848","url":null,"abstract":"<div><p>The Dhara-Ayurveda 2047 conference was organized at the University of Trans-Disciplinary Health Sciences and Technology (TDU), Bengaluru on 23rd and September 24, 2022. This was a pioneering initiative of Ministry of Culture and Ministry of Ayush to raise public awareness about the contemporary relevance of India's medical heritage. The theme of the conference was to offer innovative approaches to strengthen and globalize Ayurveda by the year 2047 to commemorate 100th year of independence of India.</p><p>More than 2000 delegates from academia and industries attended this event. This conference featured a range of components including insightful vision talks, educational exhibition, interactive practical sessions, innovation-focused competition, cultural programs, and health assessment program. Distinguished speakers shared their forward-looking perspectives on the future of Ayurveda in the year 2047 with respect to personalized nutrition, Ayurvedic healthcare, interdisciplinary medicine, AYUSH integration, Ayurvedic industry, and other related topics. The conference provided a platform for students to learn innovative approaches in Ayurveda and also awarded deserving winners for their ideas.</p><p>Thus, Dhara-Ayurveda 2047 conference served as a valuable platform for sharing knowledge and exploring the future of Ayurveda in India across different disciplines related to Ayurveda like biomedical sciences and engineering, information technology, pharmaceutical sciences and folk healers to visualize Ayurveda in the year 2047.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947623001651/pdfft?md5=87f29121bb8405cca6ae9516c4382072&pid=1-s2.0-S0975947623001651-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139494112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Millets as a dietary supplement for managing chemotherapy induced side effects","authors":"Swagata Dilip Tavhare","doi":"10.1016/j.jaim.2024.100901","DOIUrl":"https://doi.org/10.1016/j.jaim.2024.100901","url":null,"abstract":"<div><p>Millets, the nutria-cereals, are one of the oldest utilized grain. Millets are reported to possess nutraceuticals health benefits which include improvement in functioning of digestive system, reduction in cholesterol, prevention of heart disease, protection against diabetes, lowering risks of cancer etc. With the widespread commemoration of the International Year of Millets in 2023, the Indian government is moving towards the global recognition of millets in light of its medicinal value in correction of lifestyles diseases. One of the common non-communicable diseases is cancer. Chemotherapy is used as adjuvant, neo-adjuvant or as a combination, in metastatic settings. It is linked to outcomes, but it also has unfavorable side effects that lower a patient's quality of life. The reported chemotherapy side effects includes loss of appetite, nausea, vomiting, weakness, hair loss, osteoporosis, immunological suppression and gastric disturbances such as dry mouth, altered taste, ulcers, constipation etc. The effectiveness of tumor therapy and the extension of treatment are both influenced by side effect management. One way to help cancer patients with their polypharmacy load is through dietary management. Rich in phytochemicals, fiber, vitamins, and minerals, millets can be suggested as a dietary therapeutic intervention in addition to chemotherapy. Being widely accessible, cost effective, nutrient-dense, high in fiber, gluten-free, anti-inflammatory, antioxidant, lipid lowering, gastro-protective, immunomodulator in action, millets can serve as a good diet choice to minimize side effects of chemotherapy.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947624000160/pdfft?md5=b89541f1c9625aa2585cba8c52ccdfa7&pid=1-s2.0-S0975947624000160-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139986978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Homeopathic preparation of Allium sativum abrogates OxLDL mediated atherogenic events in macrophages: An in vitro and in silico approach","authors":"Thangarajeswari Mohan ,&nbsp;Abinayaa Rajkumar ,&nbsp;Gokulprasanth Panchalingam ,&nbsp;Debadatta Nayak ,&nbsp;Malathi Raghunathan ,&nbsp;Kalaiselvi Periandavan","doi":"10.1016/j.jaim.2023.100850","DOIUrl":"https://doi.org/10.1016/j.jaim.2023.100850","url":null,"abstract":"<div><h3>Background</h3><p>Oxidized LDL (OxLDL), the key player in atherogenesis modulates endothelial dysfunction, initiates monocyte recruitment, accentuates foam cell formation, and flares up inflammatory and apoptotic events. Even though homeopathic preparation of <em>Allium sativum</em> has been proved to be an anti-inflammatory, anti-apoptotic and anti-atherogenic agent, its mechanism of action on abrogating OxLDL mediated foam cell formation is yet to be explored.</p></div><div><h3>Objective</h3><p>This study was designed to bring out the role of homeopathic preparation of <em>Allium sativum</em> in curbing OxLDL mediated cellular inflammation in IC-21 cells exposed with OxLDL.</p></div><div><h3>Materials and methods</h3><p>OxLDL was used to induce oxidative damage in the IC-21 macrophage cells. Assessment of inflammatory cytokines, localization of NFκB, detection of apoptosis and the <em>in silico</em> analysis were performed in this study.</p></div><div><h3>Results</h3><p>The current study portrays the efficacy of homeopathy medicine as an anti-inflammatory agent, in reducing the levels of inflammatory cytokines and its mRNA expression, suppressing the activity of NFκB and preventing apoptosis in OxLDL treated IC-21 cells.</p></div><div><h3>Conclusion</h3><p>To conclude, homeopathic preparation of <em>Allium sativum</em> 6C and 30C potencies are capable of controlling the transcriptional activity of NFκB and apoptosis in IC-21 cells exposed to OxLDL. These results implicate that <em>Allium sativum</em> homeopathic drug can be used as anti-inflammatory agent in reducing atherogenic events as it is capable of preventing OxLDL-mediated injury to macrophages.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947623001675/pdfft?md5=59be8dce99ea494ed41d31b799366875&pid=1-s2.0-S0975947623001675-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139435969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Technology from traditional knowledge - Vrikshayurveda-based expert system for diagnosis and management of plant diseases","authors":"Laxmi B. Rananavare ,&nbsp;Sanjay Chitnis","doi":"10.1016/j.jaim.2023.100853","DOIUrl":"https://doi.org/10.1016/j.jaim.2023.100853","url":null,"abstract":"<div><p>Vrikshayurveda (An ancient Indian science of plant life) includes complete plant-life knowledge compendium of plant physiology, horticulture, pathology, and treatment. Though translation of the manuscript is available, the knowledge contained in the translation is not easily accessible to ordinary farmers who want answers to their specific problems or researchers who want references for specific topics without having to read the complete book. This research work proposes to convert the knowledge in the manuscript form to an expert system form which can provide the solutions to specific queries from the farmers and agriculture stakeholders. A rule based expert system using backward chaining Expert System is developed. The database in this design has ten diseases. The evaluation is done for all the dataset. The results are compatible with the expert's diagnosis. Thus the users can get comprehensive information on Vriksha-Ayurvedic expertise on all elements of disease and plant protection.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947623001705/pdfft?md5=bdd5f7c44d0d8efe76cc956a2db2d7d2&pid=1-s2.0-S0975947623001705-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139435971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrative vision in cancer research, prevention and therapy","authors":"Ashok DB. Vaidya M.D.,Ph.D.","doi":"10.1016/j.jaim.2023.100856","DOIUrl":"10.1016/j.jaim.2023.100856","url":null,"abstract":"<div><p>There is already a significant global initiative to explore the synergy between traditional medicine (TM) and oncology, for holistic best care of cancer patients. Integrative oncology clinics have emerged with operational efficiency. What is needed now is an integrative vision that inspires to seamlessly coordinate the <em>trans</em>-system efforts in cancer research and rapidly translate the positive outcomes into prevention and treatment of cancer. The current dominant paradigm to consider TM only for complementary and alternative adjunct usage cannot inspire state-of-the art research and development on TM leads and serendipitous discoveries. Ayurvedic concepts of <em>Vyadhi-kshamatwa</em> (Immune resistance), <em>Shatkriyakala</em> (Six stages of a disease) and <em>Hetuviparya Chikitsa</em> (Reversal of pathogenetic factors) need to be synergized with ayurvedic pharmacoepidemiology, reverse pharmacology, observational therapeutics, ayurgenomics, ayurvedic biology, and reverse ayurceutics. Such a paradigm-shifting vision may lead to pragmatic translational research/practice and system obstacles and novel bridges in Integrative Oncology.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947623001730/pdfft?md5=b8f201dcaf2557f86b4235e41989a995&pid=1-s2.0-S0975947623001730-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139097915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"History of safe use of herbs - Approaches for documenting evidence","authors":"D.B. Anantha Narayana ,&nbsp;N.B. Brindavanam ,&nbsp;Sabina Shirsekar","doi":"10.1016/j.jaim.2023.100849","DOIUrl":"https://doi.org/10.1016/j.jaim.2023.100849","url":null,"abstract":"<div><p>Approval by regulatory authorities for commerce of herbs to different nations is lengthy process involving quality, safety, and efficacy data submission for the herbs under different category. Submission of documented history of use of herbs in such steps has gained momentum in the last decade globally. EU Directives and Food Regulations, India, specifically describes this requirement. However, authors have not seen any broad guidelines on how to document such evidence. This paper attempts to provide inputs for wider consultations to lead to guideline development.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947623001663/pdfft?md5=cbefd9563332b47d39267dfd3b5f3ef9&pid=1-s2.0-S0975947623001663-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139399440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of gummy bear supplements and in vitro exploration of antioxidant and antiproliferative potential of Nuciferine","authors":"Veerabhuvaneshwari Veerichetty ,&nbsp;Iswaryalakshmi Saravanabavan ,&nbsp;Aarushi Pradeep ,&nbsp;Ramapalaniappan Abiraamasundari","doi":"10.1016/j.jaim.2023.100868","DOIUrl":"https://doi.org/10.1016/j.jaim.2023.100868","url":null,"abstract":"<div><h3>Background</h3><p>Nuciferine's extensive therapeutic potential, including its robust antioxidant properties, is explored in response to the growing consumer preference for value-added organic foods.</p></div><div><h3>Objective</h3><p>This study focuses on the formulation of gummy bear supplements fortified with nuciferine from <em>Nelumbo</em> <em>nucifera</em>. The research highlights nuciferine's ability to combat oxidative stress induced by reactive oxygen species (ROS) and examines its application in maintaining basal ROS levels during oxidative stress conditions in skin melanoma cells.</p></div><div><h3>Methods</h3><p>Characterization of extracted nuciferine through FTIR and UV–vis spectroscopy ensures product quality, while sensory evaluation compares honey and sugar as natural sweeteners for optimal flavor and consumer preference. SK-Mel-28 cellular ROS levels were measured using 2′,7’ –dichlorofluorescin diacetate dye before and after nuciferine treatment. SK-Mel-28 cell viability and dose response of nuciferine treatment was assessed using MTT assay.</p></div><div><h3>Results</h3><p>Nuciferine shows potent inhibition of SK-Mel-28 cell proliferation with an IC₅₀ of 39.31 ± 5.280 μg/ml and showed no cytotoxicity in normal L6 skeletal muscle cells. This study compares the sensory properties of honey and sugar based gummy bear formulations.</p></div><div><h3>Conclusion</h3><p>This project aims to create a high-quality, health-promoting dietary supplement that aligns with the evolving trends in organic nutrition and antioxidant supplementation.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947623001857/pdfft?md5=f9e8beabe0a02071b0fa83641a695dfe&pid=1-s2.0-S0975947623001857-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139108394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traditional and contemporary herbal medicines in management of cancer: A scoping review","authors":"I. Imtiaz ,&nbsp;J. Schloss ,&nbsp;A. Bugarcic","doi":"10.1016/j.jaim.2024.100904","DOIUrl":"https://doi.org/10.1016/j.jaim.2024.100904","url":null,"abstract":"<div><h3>Background</h3><p>Cancer is one of the leading causes of death worldwide and is primarily managed by chemotherapy, radiation and surgery. Traditional medicine is widely used worldwide due to availability, affordability, wide applicability and accessibility. While potential for traditional medicines in management of cancer is well-documented, there is limited literature that collates traditional knowledge and contemporary herbal medicine practice.</p><p>To collate available evidence on herbal medicines used in the management of all cancers from traditional world-wide sources, and the management of lung and colorectal cancers in contemporary practice.</p><p>Medicinal plants with anti-cancer properties were identified following JBI methodology for scoping reviews through searches of the following sources: Trove, <span>Archive.Org</span><svg><path></path></svg>, and Henriette's herbal medicine page (traditional texts), book list available from World Naturopathic Federation white paper (contemporary naturopathic texts), and in PubMed, MEDLINE, SCOPUS, ScienceDirect, AMED and JSTOR (case studies).</p><p>Of the 1973 citations retrieved, 38 traditional texts, 3 contemporary naturopathic texts and 10 case studies were included in the review. The traditional texts (n = 110) noted the highest number of different anti-cancer herbal species, followed by case reports (n = 52) and contemporary texts (n = 13).</p><p>This review identified various herbal medicines used to treat cancer traditionally which is distinct to those found in contemporary use. Moreover, this review identified the use of herbs from other native medical systems around the world in the contemporary naturopathic practice and individual case management. The evidence presented in the review could be utilized in pre-clinical settings to research traditional preparations of herbs.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947624000196/pdfft?md5=ebb753e1b8d3fddedab7b58a305631cd&pid=1-s2.0-S0975947624000196-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139935457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ayurvedic clinical decision-making methods to predict, prevent and manage childhood allergic disorders","authors":"K.P. Karthik ,&nbsp;Aparna Dileep ,&nbsp;S. Rajagopala ,&nbsp;Mahapatra Arun Kumar ,&nbsp;Prasanth Dharmarajan ,&nbsp;Jessica Vellela","doi":"10.1016/j.jaim.2023.100857","DOIUrl":"10.1016/j.jaim.2023.100857","url":null,"abstract":"<div><p>Allergy is a conundrum lacking satisfactory answers despite its global prevalence. Traditional systems of medicine may contain sustainable and effective solutions for the same. For mainstreaming them, an evaluation based on the system's own methods is inevitable rather than symptom-based correlations. Atopy is a novel entity in Ayurveda, but the methods of tripartite delineation (disease pattern, disease targets and influencing factors) of novel diseases and multifactorial approach to diagnosis and management in Ayurveda can bring about comprehensiveness in collection and categorization of data regarding the entity. This in turn can make the prediction, prevention and management of the same more precise, effective and sustainable. The article provides a template for the application of Ayurvedic biological framework in the diagnosis and management of novel diseases, with special reference to childhood allergic disorders.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947623001742/pdfft?md5=344aff4c276b834007fcb34e52011caa&pid=1-s2.0-S0975947623001742-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139491100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A scoping review of Ayurvedic rasayana adaptogens in oncology","authors":"Cairn Wu ,&nbsp;Ashley Mulakaluri ,&nbsp;Pranay Chaurasia ,&nbsp;Sindhu Suryanarayana ,&nbsp;Ambreen Singh ,&nbsp;Nicole Krauss ,&nbsp;Peggy Tahir ,&nbsp;Charles Elder ,&nbsp;Rammanohar Puthiyedath ,&nbsp;Anand Dhruva","doi":"10.1016/j.jaim.2023.100879","DOIUrl":"10.1016/j.jaim.2023.100879","url":null,"abstract":"<div><h3>Introduction</h3><p>Rasayanas are Ayurvedic natural products that have adaptogenic effects. The extensive research on rasayanas in oncology is not currently well summarized. The aim of this review is to investigate the range and nature of the current body of research, identify gaps in knowledge, and to summarize the existing literature as it relates to Ayurvedic rasayanas and oncology.</p></div><div><h3>Materials and methods</h3><p>A comprehensive literature search of fifteen Ayurvedic adaptogen rasayanas was conducted using three main concepts: Ayurvedic herbal terms, neoplasm terms, and oncological pathways. After screening was performed, key variables were extracted (tagged) including type of adaptogen, cancer type, type of study design, constituent type, and mechanisms of action (MOA). The results were synthesized and summarized using descriptive statistics and narrative summaries.</p></div><div><h3>Results</h3><p>Five hundred and eighty-four articles were reviewed and tagged. The two most tagged adaptogens were <em>Glycyrrhiza glabra (Yashthimadhu/licorice)</em> (n = 166 (28.4 %)) and <em>Withania somnifera</em> (<em>Ashwagandha</em>) (n = 151 (25.9 %)). The most frequently tagged cancer diagnostic categories were gastrointestinal (n = 175 (30 %)), and breast (n = 126 (21 %)). Most of the articles focused on <em>in vitro</em> studies (n = 470 (80.3 %)). Of the 12 MOA tags, the most frequently tagged was apoptosis (n = 298 (29.2 %)).</p></div><div><h3>Conclusion</h3><p>A large body of pre-clinical literature exists on adaptogen rasayanas in oncology, indicating this field of research is still in its early phase. Comparatively few studies focused on the effects on the immune system. Given the growing interest in immuno-oncology therapeutics and the potential impact of adaptogen rasayanas on the immune system, future research may focus more in this area, along with work that is more directly linked to future clinical studies.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947623001961/pdfft?md5=980b8674ea98d3ab980f452093b619f7&pid=1-s2.0-S0975947623001961-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139671876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}