Journal of Ayurveda and Integrative Medicine最新文献

{"title":"The neurophysiological effects of yogic meditation observed in electroencephalography patterns and neurotransmitter levels: A narrative review of scientific evidence","authors":"Sunil Singh Yadav ,&nbsp;Simran Mittal ,&nbsp;Sangeeth Somanadhapai ,&nbsp;Rita Thapa ,&nbsp;Sanjay Yadav ,&nbsp;Massimiliano Buoli ,&nbsp;Toran Singh ,&nbsp;Alka","doi":"10.1016/j.jaim.2025.101312","DOIUrl":"10.1016/j.jaim.2025.101312","url":null,"abstract":"<div><div>Yogic meditation, involving focused awareness, is gaining scientific attention for its impact on brain function and neurochemical balance. It enhances autonomic control and influences neurotransmitters related to emotional and cognitive health.</div><div>This narrative review explored scientific studies on the effects of yogic meditation on EEG patterns and neurotransmitter levels. 21 peer-reviewed articles were selected through a structured search of PubMed, PubMed Central, and Google Scholar.</div><div>The findings indicate that yogic meditation promotes coherent brainwave activity and modulates neurotransmitters, such as gamma-aminobutyric acid, thereby reducing anxiety, improving emotional regulation, and providing pain relief and autonomic stability.</div><div>The studies literature suggest that yogic meditation may enhance brain function and emotional well-being, but these findings remain preliminary and require more well-designed confirmation.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"17 2","pages":"Article 101312"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147480298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitude and Practice of selected Dinacarya practices among BAMS Students in Kerala - A Cross Sectional Study","authors":"K. Aakash ,&nbsp;Anupama Krishnan","doi":"10.1016/j.jaim.2026.101320","DOIUrl":"10.1016/j.jaim.2026.101320","url":null,"abstract":"<div><h3>Background</h3><div>Ayurveda students in India learn <em>Dinacarya</em> practices (daily routines) during BAMS course (Undergraduate Ayurveda medical education course), with limited research on its awareness and adoption. A valid database on Knowledge-Attitude Practice (KAP) status of <em>Dinacarya</em> practices is ideal for self-evaluation and further student improvement.</div></div><div><h3>Objective</h3><div>To assess the KAP status of selected <em>Dinacarya</em> practices among BAMS students in Kerala.</div></div><div><h3>Materials and Methods</h3><div>Cross-sectional study among 216 students aged 18-27 years, using stratified two-stage sampling from two strata - Government/Aided and Private Ayurveda colleges in Kerala (7 colleges). Semi constructed KAP questionnaire on selected ten <em>Dinacarya</em> developed through literature review, focus group discussion (FGD),content and face validity checking. Population estimates calculated using survey weights and Multiple linear regression (MLR) to identify predictors of KAP components and composite scores was used.</div></div><div><h3>Result</h3><div>Population-weighted mean K, A, P and total KAP scores of Dinacarya came to 6.65 (SE=0.48), 3.25 (SE=0.22), -5.01 (SE=0.29) and 4.89 (SE=0.61) respectively. MLR analysis revealed that knowledge was primarily determined by institutional factors, attitude reflects lifestyle pathways and Practice projects multilayered predictors encompassing environmental and institutional factors.</div></div><div><h3>Conclusion</h3><div>Weighted KAP analysis revealed knowledge scores exceeding attitude and practice scores, indicating a knowledge-practice gap. Institutional entity emerged as overall determinant, residence type and psychological disposition are crucial factors.Health behaviors practice progressively decline with advancement in academic years.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"17 2","pages":"Article 101320"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147425667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stability studies on Ghanvati formulated from Psidium guajava Linn. leaf decoction","authors":"Poonam Daswani ,&nbsp;Sanjeevani Deshkar ,&nbsp;Asha Thomas ,&nbsp;Nilima Dharkar ,&nbsp;Roshani Pagar ,&nbsp;Juilee Jagtap ,&nbsp;Sarika Chaturvedi ,&nbsp;Nerges Mistry","doi":"10.1016/j.jaim.2025.101274","DOIUrl":"10.1016/j.jaim.2025.101274","url":null,"abstract":"<div><div>We developed a formulation (tablet, <em>Ghanvati</em>), from <em>Psidium guajava</em> L. leaf decoction and assessed its stability using standard guidelines. The organoleptic and physicochemical analysis of the leaves and prepared extract was undertaken. The tablets were subjected to friability, the dimensions were measured and its stability [hardness, disintegration, and loss on drying (LOD)] tested on 0-day and the end of 3, 6, and 12 months at ambient, intermediate and accelerated conditions as per International Council for Harmonization Q1 (R2) guidelines. Simultaneously, representative phytocompounds (gallic acid, epigallocatechin gallate, ellagic acid, and quercetin) were quantified using high performance liquid chromatography. The organoleptic, physicochemical, and friability were within specified limits. Stability studies indicated significant increase in % LOD values affecting the hardness of the tablet. With respect to phytoconstituents, epigallocatechin gallate and ellagic acid showed increase in concentration at 12 months at ambient (6.524 ± 0.93 and 8.03 ± 0.75 μg/mg, respectively) and intermediate conditions (5.53 ± 0.34 and 8.267 ± 0.87 μg/mg, respectively) compared to 0-day (4.03 ± 0.66 and 0.513 ± 0.08 μg/mg, respectively). In contrast, compared to the 0-day values (16.0 ± 0.14 and 0.8154 ± 0.13 μg/mg, respectively), the concentration of gallic acid and quercetin decreased under ambient (14.44 ± 0.99 and 0.4 ± 0.06 μg/mg, respectively) and intermediate (8.6 ± 0.69 and 0.324 ± 0.3 μg/mg, respectively) conditions. Thus, despite stability in terms of hardness and disintegration time, the hygroscopicity and chemical variability with time of the prepared <em>Ghanvati</em> warrant the need for alternative approaches to improve stability.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"17 2","pages":"Article 101274"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147427446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Agnikarma along with Ayurveda medication in management of trigger thumb - A Case Report","authors":"Bharati Samota ,&nbsp;Suman Sharma ,&nbsp;Manorma Singh ,&nbsp;Rahul Sharma ,&nbsp;Poonam Garg","doi":"10.1016/j.jaim.2026.101339","DOIUrl":"10.1016/j.jaim.2026.101339","url":null,"abstract":"<div><div>Trigger thumb is a condition caused by incongruity in diameter between the swollen flexor tendon and its sheath at the metacarpal head, often due to thickening of the A1 pulley. This results in a clicking or popping sensation during thumb extension. Treatment options include splinting, physical therapy, steroid injections, and surgical release of the A1 pulley. In Ayurveda, trigger thumb can be attributed to <em>Snayugata Vata</em> (vitiated <em>Vata</em> dosha in tendons/ligaments). <em>Agnikarma</em> is an Ayurvedic procedure, effective for treating <em>Snayugata Vata</em> and other joint disorders. A 56-year-old male patient, working in a printing press, presented with pain and swelling in his right thumb at National Institute of Ayurveda (NIA) hospital. On the basis of clinical examination, the patient was diagnosed with right trigger thumb. The patient underwent three sittings of <em>Bindu</em>-type <em>Agnikarma</em> therapy, using <em>Tamra Shalaka</em>, at site of maximum tenderness, at interval of seven days. Following treatment, the patient experienced complete resolution of symptoms with follow-up of five months. <em>Agnikarma</em> provided a successful, minimally invasive, and cost-effective alternative to surgical intervention, demonstrating its potential as an effective remedy for trigger thumb. This case study provides a lead to establish a new standardized treatment protocol and assess long term benefits of <em>Agnikarma</em> for trigger thumb.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"17 2","pages":"Article 101339"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147450631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical consensus statements on Marsha Nasya – A feasibility study towards developing clinical practice guidelines of therapeutic procedures in Ayurveda","authors":"Devi R. Nair ,&nbsp;Ashwathykutty V. ,&nbsp;Praveen Kumar K.S. ,&nbsp;Shaizi Layeeq ,&nbsp;Shruti Khanduri ,&nbsp;Bhogavalli Chandrasekhararao ,&nbsp;Narayanam Srikanth ,&nbsp;Rabinarayan Acharya","doi":"10.1016/j.jaim.2025.101298","DOIUrl":"10.1016/j.jaim.2025.101298","url":null,"abstract":"<div><h3>Background</h3><div>Modern pedagogical frameworks and recent advancements—such as quality accreditation and insurance coverage in Ayurveda—underscore the need for clear and practical guidelines for therapeutic procedures, particularly <em>Panchakarma</em>. The therapeutic procedures outlined in Ayurveda, notably <em>Panchakarma</em>, comprising five internal cleansing therapies (emesis, purgation, decoction enema, unctuous enema, and errhine therapy) currently lack published contemporary practice guidelines. Developing evidence-based, expert-endorsed clinical practice guidelines for these therapies would enhance their safety and effectiveness, ensuring their wider acceptance.</div><div>Ayurveda classical texts describe <em>Marsha Nasya</em> (MN), a therapy in which medicines mainly having an oil base are instilled in the nose in a comparatively higher dose, as a <em>Panchakarma</em> treatment that targets a range of pathological conditions, particularly those affecting the head and neck area.</div></div><div><h3>Objective</h3><div>This study aimed to develop a comprehensive set of evidence-based, expert-endorsed Clinical Consensus Statements (CCSs) for MN therapy utilizing the RAND/UCLA Appropriateness Method (RAM).</div></div><div><h3>Methods</h3><div>Best Practice Statements (BPSs) were developed based on an extensive literature review, inputs from physicians, and a survey conducted across multiple healthcare facilities. Nine experts participated in rounds 1 and 2 of RAM. The panelists rated each of these statements, and the statements that were deemed appropriate statistically were included in the final set of recommendations. The study was prospectively registered in the Clinical Trial Registry of India (CTRI number: CTRI/2023/05/052422 dated May 09, 2023) and PREPARE (Practice Guideline Registration for Transparency), an international prospective register for clinical practice guidelines. (PREPARE-2024CN612).</div></div><div><h3>Results</h3><div>A consensus was reached on 63 BPSs across six domains: the general domain, the preparatory procedures domain, the main therapeutic procedure domain, the post-therapy procedures domain, the dosage domain, and the quality assurance domain.</div></div><div><h3>Conclusions</h3><div>The detailed, expert - endorsed and evidence - based statements represent the important procedural aspects of MN and can be the basis for further clinical validation and practice of MN. The study may serve as a model for developing evidence-informed clinical practice guidelines for <em>Panchakarma</em> therapies and other therapeutic procedures in Ayurveda and can offer valuable guidance to clinicians, researchers, students, and policymakers.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"17 2","pages":"Article 101298"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147425668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A conference report: The UK's first Ayurveda and integrative healthcare summit","authors":"Coll de Lima Hutchison ,&nbsp;Andrea Nuñez Casal ,&nbsp;Amarjeet Bhamra ,&nbsp;John D.H. Porter ,&nbsp;Mahesh Mathpati","doi":"10.1016/j.jaim.2025.101310","DOIUrl":"10.1016/j.jaim.2025.101310","url":null,"abstract":"","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"17 2","pages":"Article 101310"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147427447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A preliminary study on Tapyadi Loha for the treatment of hepatic encephalopathy based on Insilico and Invitro analysis","authors":"Shruti Chindam ,&nbsp;Urmila Aswar ,&nbsp;Chinmay Phondekar","doi":"10.1016/j.jaim.2025.101295","DOIUrl":"10.1016/j.jaim.2025.101295","url":null,"abstract":"<div><h3>Background</h3><div>Hepatic encephalopathy (HE) is a neuropsychiatric disorder linked to liver dysfunction, commonly occurring in cirrhosis or acute liver failure. Existing treatments like lactulose and rifaximin provide only symptomatic relief and cause gastrointestinal side effects, emphasizing the need for alternative therapies. <em>Tapyadi Loha</em> (TL), a classical Ayurvedic herbomineral formulation, is traditionally used in clinical practice for HE lacks scientific evidence.</div></div><div><h3>Objectives</h3><div>To perform preliminary evaluation of TL in the management of HE through <em>in silico</em> and <em>in vitro</em> analysis.</div></div><div><h3>Material and methods</h3><div>Activity markers of TL were screened using IMPPAT, SwissADME, and MolSoft based on ≥30 % oral bioavailability and drug-likeness scores of 0–1. Potential HE-related targets were identified through SwissTarget Prediction, SuperPred, BindingDB, and GeneCards, with overlapping targets analyzed via PPI networks using STRING and Cytoscape. Molecular docking in Schrodinger's Maestro revealed good binding affinity phytoconstituents, which were quantified by LC-MS/MS as per CCRAS guidelines. Their hepatoprotective activity was validated in HepG2 cells, while antioxidant effects were confirmed using the DPPH assay.</div></div><div><h3>Results</h3><div>Gene ontology and KEGG analyses revealed enrichment in cancer and hepatitis B pathways, notably NF-κB, TNF, and TLR signalling. Docking studies identified strong binding of gallic acid, quercetin, ascorbic acid, and luteolin, validated by LC-MS/MS. <em>In vitro</em>, TL treatment significantly improved HepG2 cell viability in thioacetamide-induced toxicity in a dose dependent manner, confirming its hepatoprotective potential. Additionally, TL demonstrated antioxidant activity in the DPPH assay.</div></div><div><h3>Conclusion</h3><div>The study examined the potential molecular targets, important genes, and signalling pathways of TL and its connection to HE using a network pharmacology approach. HepG2 cell line research showed that TL increased cell viability in a dose-dependent way. The study supports TL's possible neuroprotective and hepatoprotective benefits.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"17 2","pages":"Article 101295"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147306215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three years of chemotherapy tolerance with concurrent Ayurvedic treatment in a metastatic lung adenocarcinoma: A case report","authors":"Ranjit G. Nimbalkar ,&nbsp;Prathamesh A. Marne ,&nbsp;Vaishnavi M. Kulkarni ,&nbsp;Akshay M. Baheti ,&nbsp;Anil T. Pawar ,&nbsp;Amol A. Tagalpallewar ,&nbsp;Manasi R. Nimbalkar","doi":"10.1016/j.jaim.2026.101325","DOIUrl":"10.1016/j.jaim.2026.101325","url":null,"abstract":"<div><div>Lung adenocarcinoma, a prevalent form of non-small cell lung cancer, presents significant challenges due to its advanced stage at diagnosis and heterogeneity. This case report details the therapeutic journey of a 61-year-old female patient diagnosed with metastatic lung adenocarcinoma, managed through an integrative approach combining chemotherapy and Ayurvedic treatment. Conventional therapy consisted of carboplatin, pemetrexed, and geftinib, targeting both primary and metastatic sites. Concurrent Ayurvedic treatment was introduced to alleviate chemotherapy-related side effects and enhance the patient's quality of life. Over a 36 months period, the patient demonstrated minimal side effects and a near-complete regression of the primary lung lesions. This case highlights the potential of Ayurvedic medicine as an adjunct to chemotherapy, offering improvements in symptom management and overall patient well-being, without obstructing the chemotherapy efficacy.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"17 2","pages":"Article 101325"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147450632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innate knowledge of herbal medicine among the Sonowal Kachari tribe of Lakhimpur district, Assam, India","authors":"Pramod Chandra Dihingia ,&nbsp;Deepika Borah ,&nbsp;Wungsim Zimik ,&nbsp;Prabhakar Sharma","doi":"10.1016/j.jaim.2025.101260","DOIUrl":"10.1016/j.jaim.2025.101260","url":null,"abstract":"<div><h3>Background</h3><div>The medicinal value of herbal plants is preserved in selected tribal communities of India.</div></div><div><h3>Objective</h3><div>The main objective of this study is to identify the traditional knowledge of herbal medicines in the Sonowal Kachari tribe of Lakhimpur District, Assam, India.</div></div><div><h3>Materials and methods</h3><div>The extensive data was collected in this study between April 2022 and November 2023 in the selected village of Assam, India through a face-to-face interview using a standardized questionnaire. In total, 180 elderly people, including males and females, were chosen in the age group of 50 and older.</div></div><div><h3>Results and discussion</h3><div>The results indicated that 39 plants have medicinal value. The informants reported that they used leaves (54.34 %), followed by roots (10.87 %), whole plants (8.7 %), fruits (8.7 %), flowers (6.52 %), bulbs, bark, rhizomes, latex, and stems (2.17 % each) for medicines. Out of 39 plant species reported, the study identified the use of four types of plants for the treatment of fever, followed by three plants each for the treatment of cold cough, dysentery, and skin diseases; 3 plants for the treatment of hair growth, stomach pain, bleeding, arthritis, rheumatic pain, tonics, and diarrhea; and one plant for the treatment of pneumonia, stimulants, indigestion, anti-inflammatory, burns, liver and urinary trouble, kidney stone, eczema, bone fracture, jaundice, anti-diabetic, carbuncle, constipation, dying nail, anemia, cuts and wounds, high blood pressure diseases. The study also revealed that herbs (46.15 %), trees (25.64 %), climbers (15.38 %), and shrubs (12.82 %) were used for treatment by Sonowal Kachari tribe.</div></div><div><h3>Conclusions</h3><div>This study highlights the Sonowal Kachari tribe of Assam has significant contribution to herbal medicine and offers a promising repository for discovering new therapeutics.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"17 2","pages":"Article 101260"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147425669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The classic Chinese medicine weijing decoction as a complementary intervention for respiratory diseases: A systematic review and meta-analysis","authors":"LiQi Li ,&nbsp;YuHong Zheng ,&nbsp;JiaXin Li ,&nbsp;Lin Zhao ,&nbsp;Xin Lin ,&nbsp;Hao Zhang ,&nbsp;HuiHui Chen ,&nbsp;PeiYu Yan","doi":"10.1016/j.jaim.2025.101242","DOIUrl":"10.1016/j.jaim.2025.101242","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;The incidence of pulmonary diseases remains unacceptably high, underscoring the need for improved therapeutic strategies. The current therapeutic landscape, largely reliant on antibiotics and hormonal agents, is constrained by growing challenges such as drug resistance, significant toxicity profiles, and prolonged disease courses. As a time-honored TCM prescription, Weijing Decoction (WJD) is widely administered for respiratory ailments. However, a critical appraisal of the existing literature reveals a paucity of high-quality evidence. Research to date has largely been confined to anecdotal case reports or preliminary investigations with limited sample sizes, resulting in a lack of systematic assessment on the combined efficacy and safety of WJD and modern medical interventions.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;div&gt;This study aimed to systematically evaluate and meta-analyze the therapeutic efficacy of Weijing Decoction (WJD) in the management of respiratory diseases, including chronic obstructive pulmonary disease (COPD) and pneumonia.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;A comprehensive literature search was conducted across six electronic databases, including both international and Chinese-language databases, to identify randomized controlled trials (RCTs) evaluating the efficacy of WJD in the treatment of COPD and pneumonia. Data on primary outcomes, including the overall clinical efficacy rate, C-reactive protein (CRP) levels, and Traditional Chinese Medicine Syndrome Scores, were extracted and synthesized using RevMan version 5.4 software. Statistical heterogeneity across studies was assessed using the I&lt;sup&gt;2&lt;/sup&gt; test and Chi-square test. A fixed-effect model was employed in the presence of low heterogeneity (I&lt;sup&gt;2&lt;/sup&gt; ≤ 50 %, p &gt; 0.1), whereas a random-effects model was applied when significant heterogeneity was observed (I&lt;sup&gt;2&lt;/sup&gt; &gt; 50 %, p &lt; 0.1). Funnel plots were used to assess potential publication bias among the included studies.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;A total of 10 eligible studies involving 1315 patients diagnosed with respiratory diseases were included in the analysis. Patients in the control group received conventional medical treatment, whereas those in the intervention group received WJD in addition to standard therapy. The intervention group demonstrated significantly higher overall disease efficacy rates, along with marked reductions in CRP levels and lower Traditional Chinese Medicine Syndrome Scores (including symptoms such as cough and sputum production), compared to the control group (all p &lt; 0.05).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;The combination of WJD with conventional therapy appears to be an effective and beneficial treatment strategy for managing COPD and pneumonia, potentially improving clinical outcomes. This integrative approach shows promise in enhancing the quality of care and may offer additional therapeutic advantages in the managemen","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"17 2","pages":"Article 101242"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147450633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}