Journal of Ayurveda and Integrative Medicine最新文献

{"title":"Efficacy of Brahmi vati and Aswagandharista in major depressive disorder: A randomized controlled trial","authors":"Amit Sarhyal ,&nbsp;Sameeran Chate ,&nbsp;Basavaraj R. Tubaki ,&nbsp;Rajat Thakur","doi":"10.1016/j.jaim.2024.101022","DOIUrl":"10.1016/j.jaim.2024.101022","url":null,"abstract":"<div><h3>Background</h3><div>Role of Ayurveda medications in the management of Major depressive disorder (MDD) is explored.</div></div><div><h3>Objective</h3><div>To evaluate the effect of Brahmi vati and Aswagandarista in the management of MDD.</div></div><div><h3>Methods</h3><div>Study was a Randomized, Controlled, parallel group comparative clinical trial. Fifty patients meeting the MDD (DSM V) diagnostic criteria from teaching hospital were recruited in the study. They were divided in two 2 groups. Control group were administered with Escitalopram 10 mg twice a day. Ayurveda group were intervened with tablet Brahmi vati 500 mg thrice a day and Liquid Aswagandarista 10 ml thrice a day. Interventions were for 60 days. Assessments were done on every 15th day. Assessments criteria included Hamilton Depression Rating scale (HDRS), Hamilton Anxiety Rating scale (HARS), UKU Side effect scale (UKU), Brief Psychotic Rating Scale (BPRS), WHO quality of life -BREF (WHOQOL-BREF), Pittsburgh Sleep Quality Index (PSQI) and Clinical Global Impression scales (CGI) were assessed at all the time points. Blood parameters like Haemoglobin, Serum creatinine and Liver function tests were evaluated at pre and post study.</div></div><div><h3>Results</h3><div>Between group comparison showed significant improvements in WHOQOL-Bref (p &lt; 0.001), UKU (p = 0.04) favouring Ayurveda group and PSQI (p = 0.02) improvements in control group. Improvements in other parameters were comparable. Within group assessment showed significant (p &lt; 0.001) improvement in HDRS, HARS, BPRS, CGI-S, CGI-GI in both the groups. Liver function tests and serum creatines were within normative limits.</div></div><div><h3>Conclusion</h3><div>Ayurveda medications produced significant improvements comparable to escitalopram with additional advantages in quality of life and side effects profile.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"15 6","pages":"Article 101022"},"PeriodicalIF":1.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142779188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of ayurveda medications, Brahmi vati and Saraswatarista, in generalized anxiety disorder- a randomized controlled trial","authors":"Varsha B. Gonugade ,&nbsp;Sameeran S. Chate ,&nbsp;Basavaraj R. Tubaki ,&nbsp;Rajat Thakur","doi":"10.1016/j.jaim.2024.101033","DOIUrl":"10.1016/j.jaim.2024.101033","url":null,"abstract":"<div><h3>Background</h3><div>Ayurvedic intervention (<em>Brahmi Vati</em> with <em>Saraswatarista</em>) is explored for their possible role in management of Generalized Anxiety Disorder (GAD), a common psychiatric disorder.</div></div><div><h3>Objective</h3><div>The objective of the study was to evaluate the efficacy of <em>Brahmi Vati</em> and <em>Saraswatarista</em> in GAD.</div></div><div><h3>Methods</h3><div>Study is a randomized controlled clinical trial. Patients (n = 50) of GAD (Diagnostic and Statistical Manual of Mental Disorders (DSM-5 criteria), 18–60 years of age, either sex participated in the study. Participants were randomly divided into two groups. Group A, received escitalopram 10 mg/day for first 10 days followed by 20 mg/day for next 50 days. Group B, received Ayurvedic intervention (<em>Brahmi Vati</em> 500 mg thrice a day (TID) and <em>Saraswatarista</em> 10 ml TID) for 60 days. Assessments were with clinical parameters like Hamilton Anxiety Rating Scale (HARS), GAD 7 scale (GAD 7), Beck Depression Inventory scale (BDI), Epworth sleepiness scale (ESS), Pittsburgh Sleep Quality Index (PSQI), WHO Quality of Life- BREF (WHOQOL-BREF), Clinical Global Improvement scale (CGI) and UKU-Side effect scale (UKU). These clinical assessments were measured on every 15th day during the intervention. Haemoglobin, liver function test (LFT), serum creatinine, serum urea were assessed before and after the study.</div></div><div><h3>Results</h3><div>Study results indicate that both the groups were comparable in HARS, GAD7, BDI, WHOQOL-Bref and CGI-Severity. Group B was better in PSQI (standard mean difference = 0.87, 95% CI: 0.28, 1.43), ESS (standard mean difference = 1.42, 95% CI: 0.78, 2.02), CGI [global improvement (standard mean difference = 0.82, 95% CI: 0.23,1.28) and efficacy index (standard mean difference = 0.97, 95% CI: 0.37,1.54)] and had better adverse events profile (standard mean difference = 0.79, 95% CI: 0.21, 1.36). Both the groups had a good safety profile assessed through liver and renal profiles.</div></div><div><h3>Conclusion</h3><div>Ayurveda interventions has additional advantages likes improvements in sleep profile, lesser adverse events and better global improvement in management of GAD.</div><div>CTRI Registration Number is CTRI/2020/09/027750.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"15 6","pages":"Article 101033"},"PeriodicalIF":1.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11652770/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Classical ayurveda management of TCH (taxane, carboplatin, and herceptin) based chemotherapy induced peripheral neuropathy- A case report","authors":"Zankhana Buch ,&nbsp;Suprabha Hegde ,&nbsp;Aishwarya Lakshmi ,&nbsp;Swathi Bhat","doi":"10.1016/j.jaim.2024.101044","DOIUrl":"10.1016/j.jaim.2024.101044","url":null,"abstract":"<div><p>Although empirical data on the influence of Ayurveda on Chemo/Radiotherapy-induced side effects are limited, its methodological framework, grounded in a 'systems thinking' perspective, enables the precise delineation of the pathogenic stage of these side effects. This, in turn, facilitates the development of a strategy to address the decline in the quality of life parameters commonly associated with cancer treatment. Ayurveda personalized approach to disease management typically involves providing customized diets, lifestyle adjustments, medications, and detoxification therapies that target the entire body.</p><p>We present a case involving a patient with numbness and pain in the right hand after undergoing chemotherapy who was referred to us by an oncologist for symptom management. This case report demonstrates the Ayurveda approach for establishing the etiology, pathogenesis, pathophysiology, and treatment of Chemotherapy-Induced Peripheral Neuropathy (CIPN) resulting from taxane-based chemotherapy. Following Ayurveda intervention, the patient exhibited significant improvements in symptoms and quality of life parameters.</p><p>This case report systematically illustrates the application of Ayurveda approach in CIPN management.</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"15 5","pages":"Article 101044"},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947624001591/pdfft?md5=54366e63e4f13d6b195d6ea5fecbf6b7&pid=1-s2.0-S0975947624001591-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142150813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ayurvedic management of hydatid cyst of lungs: A case report","authors":"Praveen K. Yadav ,&nbsp;Pradeep S. Shindhe ,&nbsp;Ramesh S. Killedar ,&nbsp;Mandeep Singh","doi":"10.1016/j.jaim.2024.101000","DOIUrl":"10.1016/j.jaim.2024.101000","url":null,"abstract":"<div><div>Cystic echinococcosis (CE), which is present in all parts of the world, is caused by the bacterium <em>Echinococcus granulosus.</em> One of the most serious parasitic infectious diseases affecting both humans and animals, CE causes hydatid cysts that can lodge in various host organs, including the liver, lungs, heart, and brain, which can be fatal. Treatment options for cystic echinococcosis are active anthelmintics, surgery, and percutaneous aspiration. Numerous scolicidal chemical agents are in practice, but due to increased drug resistance and adverse reactions associated with drugs, usage is limited. Finding alternative therapies with the least or no side effects to manage the condition is the need of the hour. Here, we report a case of an asymptomatic hydatid lung cyst that was managed using Ayurvedic treatment principles. A 57-year-old businessman, asymptomatic, came with a diagnosis of Hydatid lung disease confirmed by CT scan. Surgery was advised, but the patient approached for Ayurveda treatment. The case was treated with oral medicines like <em>Arogyavardhini gutika, Goarka, Kanchanara guggulu, Vidangasava, Kapalabhati pranayama</em> for a period of 8 months. Complete resolution of the cyst was seen, which was evident by a CT scan. Promising results were seen in the present case, but further research in this area is required to produce evidence-based results.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"15 5","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142442840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review and meta-analysis focusing on the use of ayurvedic medicine in cerebral palsy","authors":"A.M.O. Rocha ,&nbsp;C.A. Len ,&nbsp;F.H. Santos ,&nbsp;S.B.O. Iglesias ,&nbsp;J.R. Bissoto","doi":"10.1016/j.jaim.2024.101035","DOIUrl":"10.1016/j.jaim.2024.101035","url":null,"abstract":"<div><div>Integrative practices have been incorporated into palliative care to provide holistic and multidimensional care for patients.</div><div>This study aims to identify the scope of integrative practices, specifically whole medical systems, and demonstrate its safety and efficacy, specially in children with cerebral palsy.</div><div>Key databases, including Embase, Cochrane, Medline/PubMed, Scopus, Google Scholar, Lilacs and Scielo were searched using specific terms.</div><div>Only randomized and non-randomized clinical trials were included for meta-analysis purposes. Case-control, cohort, cross-sectional or retrospective observational studies were also included for the systematic review. Participants included children aged 0–18 years receiving palliative care for cerebral palsy and undergoing Ayurvedic Medicine practices.</div><div>Descriptive analysis was conducted, including data such as year; author; design; sample size; intervention and comparison; outcomes and conclusion.</div><div>Two interventional studies compared Ayurvedic practices with each other or with physiotherapy in children with cerebral palsy. The meta-analysis demonstrated an improvement in spasticity for children using Ayurvedic medicine. However, there were limitations in terms of heterogeneity in interventions, control groups, and assessed outcomes.</div><div>Integrative practices, including Ayurvedic medicine have the potential to improve quality of life, manage disease symptoms and provide emotional support. However, more robust evidence is needed to support their widespread use. The use of Ayurvedic medicine showed evidence of improvement in spasticity for children with cerebral palsy.</div></div><div><h3>Registration number</h3><div>Prospero CRD 42020198399.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"15 5","pages":"Article 101035"},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating Ayurveda and modern mainstream medicine","authors":"K.P. Mohanan","doi":"10.1016/j.jaim.2024.100997","DOIUrl":"10.1016/j.jaim.2024.100997","url":null,"abstract":"<div><div>This article is an attempt to understand the challenge of integrating the education provided by BAMS programs and MBBS programs, in order to initiate the process of integrating research and practice in Ayurveda and Modern Mainstream Medicine. The specific issues discussed in the article are framed within the broader context of the challenge of integrating any two bodies of knowledge, theories, or knowledge systems in education and research.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"15 5","pages":"Article 100997"},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ayurinformatics Laboratory- A synergy platform for Ayurveda and technology","authors":"Prashant Kumar Gupta ,&nbsp;Tanuja Manoj Nesari","doi":"10.1016/j.jaim.2024.101019","DOIUrl":"10.1016/j.jaim.2024.101019","url":null,"abstract":"<div><p>The Ayush sector has attained buoyant growth in the past decade as a science, public health, medicine, and industry. Artificial Intelligence, computational drug designing, and other combinatorial techniques could further accelerate the sector's growth. In this edition, we delve into the confluence of Ayurveda and technology, a theme that resonates profoundly in the contemporary healthcare and wellness landscape. The fusion of Ayurveda, an ancient system of medicine rooted in holistic well-being, with cutting-edge technology, is not just a paradigm shift but a necessary evolution in pursuing an integrated healthcare system where all systems have their defined, recognized, and respected contribution. Here, We are highlight one-such fusion initiative \"Ayurinformatics Laboratory\".</p></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"15 5","pages":"Article 101019"},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0975947624001347/pdfft?md5=66284fa327c82e9a05891c2fcff945d0&pid=1-s2.0-S0975947624001347-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Introduction of journal clubs for UG students of Ayurveda, a dire necessity","authors":"Gaurav Soni","doi":"10.1016/j.jaim.2024.100977","DOIUrl":"10.1016/j.jaim.2024.100977","url":null,"abstract":"","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"15 5","pages":"Article 100977"},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142433465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Raupya Suvarna Sutashekhara, a herbo-mineral-metallic formulation as adjunct Oral Ayurvedic Medicine on long-term survival in patients of malignant brain tumor","authors":"Sadanand Sardeshmukh,&nbsp;Vineeta Deshmukh,&nbsp;Arvind Kulkarni,&nbsp;Swapna Kulkarni,&nbsp;Vasanti Godse,&nbsp;Shrinivas Datar,&nbsp;Sushama Bhuvad,&nbsp;Shweta Gujar,&nbsp;Sameer Gore,&nbsp;Bhagyashree Sardeshmukh,&nbsp;Vinita Awalkanthe,&nbsp;Anita Shingte,&nbsp;Sneha Dalvi,&nbsp;Vijay Radye,&nbsp;Sandeep Chavan","doi":"10.1016/j.jaim.2024.101070","DOIUrl":"10.1016/j.jaim.2024.101070","url":null,"abstract":"<div><h3>Background</h3><div>The incidence of brain tumors poses a significant threat, particularly with high-grade tumors that exhibit rapid growth and can significantly impair the patient's quality of life, despite treatment modalities. Ayurveda, a natural system of medicines helps to enhance health benefits when used as a complementary therapy in combination with conventional treatment through various herbal, herbo-mineral or herbo-mineral-metallic formulations. One of such formulations, <em>Raupya Suvarna Sutshekhara (RSS),</em> has <em>Raupya bhasma</em> and <em>Suvarna bhasma</em> (incinerated Silver and Gold respectively) ingredients and they are described as <em>Rasayana</em> (immunomodulatory) and possess <em>Medhya</em> (enhances the brain functions and intelligence) activity.</div></div><div><h3>Objective</h3><div>The study documents effects of <em>Raupya Suvarna Sutshekhara</em> in alleviating symptoms of malignant brain tumors.</div></div><div><h3>Materials and methods</h3><div>This retrospective cohort study was done for malignant brain tumor patients (n = 110) registered at our centre who were treated with <em>Raupya Suvarna Sutshekhara</em> 125 mg–250 mg (a herbo-mineral metallic formulation) as a treatment of choice of neural tonic along with supporting Ayurvedic medicines. Treatment response evaluation period ranged from 3 months to 5 years (median period 29 weeks). Clinical symptoms, weight, Karnofsky Performance Score (KPS), Quality of Life (QoL) score, and survival data with respect to treatment with RSS were analyzed.</div></div><div><h3>Results</h3><div>RSS showed a very significant (<em>p</em> &lt; 0.001) effect on symptoms related to memory loss, headache, imbalance, loss of appetite, and generalized weakness while significant (<em>p</em> &lt; 0.05) decrease in urinary incontinence, seizures, difficulty in thinking/articulating, and weakness in one part/side of the body. However, a not-quite significant change was seen in symptom confusion/disorientation. No significant improvement was seen in vision changes, facial numbness or tingling, swallowing difficulties, and tingling in extremities. Body weight and KPS also showed improvement. Patients with treatment between 2 and 5 years showed median survival up to 62 months.</div></div><div><h3>Conclusions</h3><div>It was observed that adjunct Ayurvedic treatment with RSS helped to reduce the severity of symptoms due to the tumor itself or side-effects of conventional treatments, maintain the quality of life of malignant brain tumor patients and has shown to increase survival with respect to the duration of the treatment.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"15 5","pages":"Article 101070"},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142446630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ayurveda management of migraine - a case report","authors":"Giramalla Patil ,&nbsp;Shivanand Patil ,&nbsp;Prateek Hosur","doi":"10.1016/j.jaim.2024.100983","DOIUrl":"10.1016/j.jaim.2024.100983","url":null,"abstract":"<div><div>Migraine is one of the most prevalent causes of functional disability worldwide. Migraine patients experience headaches of varying degrees, which are related with a higher level of disability and are triggered by psychological and physiological stressors. Migraine is estimated to affect 16.6% of the world's population, with women being three times more likely to experience it than men. Despite considerable advancements in modern and traditional medicine, a complete cure remains uncertain. In <em>Ayurvedic</em> treatises, migraine headache is referred to as <em>Ardhavabedhaka</em> under the classification of <em>Shiroroga</em> (diseases related to the head region).</div><div>35-year-old Indian male police inspector, suffering from recurrent right hemi-cranial headaches once in three days for the last three months, presented symptoms of <em>Tridhoshaja Ardhvabhedaka</em> (Migraine) associated with <em>Amlapitta</em> (hyperacidity).</div><div>After a thorough assessment of the patient, the treatment was meticulously planned based on the patient's <em>Dosha pradhanyatha</em> and <em>Vyadhi avastha</em> <em>(stage of disease)</em>. For the proper <em>Samprapti vighatana, Nidana parivarjana</em> (abstinance from the eitiological factors), <em>Deepana, Paachana, Siravyadha</em>, <em>Nasya</em> and <em>Dosha Shaman</em><em>a</em> <em>Chikitsa</em> principles were adopted. Further, the severity of the migraine was assessed by MIDAS and NPR score, which subsequently decreased from 19 to 4, and the NPR scale decreased from 8 to 2 till completion of the therapeutic intervention.</div><div>This case report unequivocally highlights the pivotal role of the Ayurveda treatment regimen in effectively managing migraine. Overall, effective treatment of migraine cases requires the correct assessment of <em>Dosha</em> status and <em>Vyadhi avastha</em> and the correct selection of the appropriate medicine and procedures like <em>Siravyadha and Nasya</em> at that appropriate stage of the disease.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"15 5","pages":"Article 100983"},"PeriodicalIF":1.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142500984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}