Archana Muraleedharan, Sree R. Nair, P.N. Rajeshwari
{"title":"A non-invasive Ayurveda management of venous leg ulccer- A case report","authors":"Archana Muraleedharan, Sree R. Nair, P.N. Rajeshwari","doi":"10.1016/j.jaim.2024.101073","DOIUrl":"10.1016/j.jaim.2024.101073","url":null,"abstract":"<div><div>Venous leg ulcer (VLU) is a severe complication of chronic venous insufficiency that commonly affects older individuals. It is a long-standing consequence of venous insufficiency and accounts for 70%–80% of lower limb ulcers seen in outpatient departments. These ulcers are often unresponsive to treatment and can significantly impact patients' quality of life, causing pain, sleep disturbances, and decreased mobility. Managing varicose leg ulcers is a significant challenge for physicians.A 55-year-old male presented with symptoms including pain, stiffness, discoloration, swelling in the left lower limb, and a history of non-healing ulcer. The patient was treated with <em>Patrad</em><em>a</em><em>na</em> using leaves of <em>Ricinus communis</em> (<em>Eranda patra</em>) and <em>Grihadhum</em><em>a</em><em>di lepa</em> along with oral medications such as <em>Triphal</em><em>a</em> <em>Guggulu</em> and <em>Gandhaka Ras</em><em>a</em><em>yana</em>. Each day, the change was carefully observed and documented, revealing a notable improvement by the end of the treatment (10 days). The pain, swelling, and stiffness exhibited significant reduction, accompanied by wound healing after the first follow-up of 14 days. The complete wound healing was achieved and quality of life showed improved. The patient has beenunder observation and has not reported any recurrence of ulcer in the 4 months of follow up.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 2","pages":"Article 101073"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143724963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Safe and effective management of psoriasis through Ayurveda: A case report","authors":"Guruprasad C. Nille , Monisha Bhuyan , Laxmi Narayan Gupta , Anand Kumar Chaudhary","doi":"10.1016/j.jaim.2024.101091","DOIUrl":"10.1016/j.jaim.2024.101091","url":null,"abstract":"<div><div>Ayurveda, an ancient system, offers in-depth insights into various skin disorders. It provides detailed understanding of causative factors and pathomechanisms, along with time-tested traditional treatments based on its principles. We report a 16-year chronic case of psoriasis (36-year-old male patient) with plaques and peeling erythrodermic skin rashes over the back and front of the trunk area and both legs. The scalp area and nail beds were also affected. The early involvement of joints was also noted. A two-year multimodal Ayurveda treatment has shown notable efficacy in managing chronic plaque and erythrodermic psoriasis, with no reported adverse events or side effects. The progressive events were documented in the form of photographs with the proper consent of the patient. The Ayurveda medicines, strict dietary regimen, and regular follow-ups together resulted in promising outcomes, revalidating the potential of Ayurveda in controlling psoriasis and its complications.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 2","pages":"Article 101091"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143724965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Molecular insights into anti-inflammatory activities of selected Indian herbs","authors":"Saumya Upadhyay , Rajan swami , Shweta Shrivastava , Manish Kumar Jeengar","doi":"10.1016/j.jaim.2024.101081","DOIUrl":"10.1016/j.jaim.2024.101081","url":null,"abstract":"<div><div>Inflammation is a universal response of mammalian tissue to harm, comprising reactions to injuries, pathogens, and foreign particles. Chronic inflammation, often present in allergies and autoimmune disorders, poses significant risks, potentially leading to conditions such as rheumatoid arthritis, Alzheimer's disease, asthma, and inflammatory bowel disease. It can also be a common precursor to cancer. However, Contemporary therapies like NSAIDs and corticosteroids often provide incomplete relief from chronic inflammation and carry significant side effects, underscoring the need for exploring traditional and plant-based medicines for new, effective treatments. As such, there is a growing demand for natural bioactive substances for health maintenance and disease risk reduction. Traditional and plant-based medicines, long-used in managing inflammation and other disorders, hold promise for the discovery of bioactive lead compounds and subsequent drug development for treating inflammatory disorders. This review encompasses an extensive study of the anti-inflammatory potential of selected traditional Indian herbal medicines and the associated pharmacological mechanisms of action. The inflammatory process often entails the activation of transcription factors, induction of various signaling cascades, gene expression, activation of inflammatory enzymes, and release of pro-inflammatory cytokines in inflammatory or immune cells. Detailed exploration of active components in traditional herbal medicines such as the Neem (<em>Azadirachta indica</em>), Salai guggul (<em>Boswellia serrata</em>), Green tea (<em>Camellia sinensis</em>), Saffron (<em>Crocus sativus</em>), Turmeric (<em>Curcuma longa</em>), Mangosteen (<em>Garcinia mangostana</em>), Indian mulberry (<em>Morinda citrifolia</em>), Black cumin (<em>Nigella sativa</em>), Ashwagandha (<em>Withania somnifera</em>), and Ginger (<em>Zingiber officinale</em>) reveals their potential anti-inflammatory properties. The in-depth study of these plants provides insight into their potential applications in managing inflammatory disorders. Further research and development are necessary to substantiate these findings and translate them into clinically effective therapeutics.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 2","pages":"Article 101081"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143704962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Praveen Balakrishnan, Abhayadev A, Emy S. Surendran, Lisha S. Raj
{"title":"Acute urinary retention following frequent administration of Guggulu Tiktakam Kwatha and its management - a case report","authors":"Praveen Balakrishnan, Abhayadev A, Emy S. Surendran, Lisha S. Raj","doi":"10.1016/j.jaim.2024.101086","DOIUrl":"10.1016/j.jaim.2024.101086","url":null,"abstract":"<div><div>A 72-year-old male patient, a diagnosed case of infective spondylodiscitis, was admitted in our hospital for severe pain in the right hip and lower back (in the lumbo-sacral region) in a non-ambulatory mode. Considering the criticality, we administered <em>Kwatha</em> in a <em>Muhurmuhu</em> (frequent administration) schedule. The initial medicines reduced pain, but not the elevated C-reactive protein (CRP). To reduce this elevated CRP, we administered <em>Amruthotharam Kwatha</em> and <em>Guggulu Tiktakam Kwatha</em> (GTK) in the dosage of 30 ml every 2 h for eight times. CRP started reducing, but we encountered an acute urinary retention as an adverse drug reaction. Naranjo Adverse Drug Reaction Probability Scale recording gave a score of eight, which shows that the AE could be probably due to administration of <em>Guggulu Tiktakam Kwatha</em> (GTK) in <em>Muhurmuhu</em> schedule. When the patient did not void urine for more than 6 hours, we did <em>Marma</em> therapy on left <em>Mootthira Kala Marma</em>. The patient voided urine within half an hour of <em>Marma</em> therapy. Clinically, after the medications, pain reduced considerably, CRP came to normal, and the patient came to an ambulatory mode. This case report shows that medicines like GTK should cautiously be administered, as it may complicate. This case report also focusses light on the fact that <em>Marma</em> therapy could be a possible mode of tackling acute conditions.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 2","pages":"Article 101086"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143724964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A.S. Ganesh Kumar , Selvaraj Senthilvelan , V.M. Ravichandran , P. Selva Shunmugam , V. Kamalanathan
{"title":"Scientific characterization of the Siddha medicine Pavala parpam manufacturing","authors":"A.S. Ganesh Kumar , Selvaraj Senthilvelan , V.M. Ravichandran , P. Selva Shunmugam , V. Kamalanathan","doi":"10.1016/j.jaim.2024.101079","DOIUrl":"10.1016/j.jaim.2024.101079","url":null,"abstract":"<div><h3>Background</h3><div>In general, various Siddha medicine manufacturing methods are reported without comprehensive scientific quantification of the process and product at various manufacturing stages.</div></div><div><h3>Objective</h3><div>The current work aimed to study the standard manufacturing method involved in the <em>pavala parpam</em> medicine preparation and characterization.</div></div><div><h3>Materials and methods</h3><div>The raw material for the <em>pudam</em> process was prepared by purifying the <em>pavalam</em> using lemon juice and ground with <em>thelkodukku</em> (Heliotropium indicum) decoction. Raw material was taken in a sealed <em>agal</em> for the <em>pudam</em> process cow dung cakes. The process parameter of the <em>pudam</em> process was recorded. After the <em>pudam</em> process, the finished medicine was ground using <em>nannikal kalvam</em>. The <em>pavala parpam</em> was characterized using Thermogravimetry (TG), X-ray diffraction analysis (XRD), X-ray fluorescence (XRF), Energy dispersive X-ray analysis (EDAX), Fourier transforms infrared spectroscopy (FTIR), Scanning electron microscopy (SEM), and a particle size analyzer.</div></div><div><h3>Results</h3><div>The maximum temperature of 680°C during the <em>pudam</em> process was recorded at the top location of the sealed <em>agal</em>, and the holding time above 500°C was observed to be 55 min, 75 min, and 122 min at the top, inside, and bottom locations, respectively. The analytical testing of <em>pavala parpam</em> shows the presence of calcium carbide, calcium oxide, and magnesium oxide.</div></div><div><h3>Conclusion</h3><div>The pressure developed during the <em>pudam</em> process was only 25–30 mbar, and it can be assumed that the <em>pudam</em> process happens at atmospheric pressure. 1 kg of raw materials yields 920 g of <em>pavala parpam</em>. The characterization of <em>pavala parpam</em> was done using modern scientific testing methods.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 2","pages":"Article 101079"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143684827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A prospective, randomized, open label, parallel group, comparative clinical trial to evaluate the safety and efficacy of combination of herbal oral capsule and rectal medication to improve gut health of type 2 diabetic patients having chronic kidney disease (CKD)","authors":"Suresh Patankar , Anupama Gorde , Sagar Patankar , Rajesh Raje , Chandu Devanpally , Pranjal Ausekar , Gaurav Patil , Shraddha Chitale","doi":"10.1016/j.jaim.2024.100992","DOIUrl":"10.1016/j.jaim.2024.100992","url":null,"abstract":"<div><h3>Background</h3><div>Chronic kidney disease (CKD) is a major health concern globally, with more than 850 million people suffering from it. Several studies have been carried out to reduce inflammation in CKD patients; and to study the relationship between gut microbiota and inflammation.</div></div><div><h3>Objective</h3><div>The effect of herbal formulations to improve the gut flora and reduce inflammation has not been studied earlier. The study aims to evaluate effect of herbal formulation combined with standard of care (SOC) treatment compared to SOC.</div></div><div><h3>Methods</h3><div>A prospective, randomized, parallel group clinical trial was planned on 90 patients split equally into standard of care (SOC) with herbal treatment (IP) and only SOC groups. The change in the abdominal pain score, percent change in the pathogenic and non-pathogenic microbiome were the key endpoints of interest. The safety assessment was in terms of adverse events, changes in hematological and biochemical parameters.</div></div><div><h3>Results</h3><div>The demographic and other patient characteristics showed statistically non-significant differences between two groups. On day 90, the median abdominal score in SOC + IP group (2.00) was significantly lower than that of SOC group (3.00) (p = 0.002). The quality of life score improved significantly in SOC + IP group (p < 0.001), unlike SOC group. There was significant reduction in pathogenic microbes in SOC + IP group; however, the reduction in non-pathogenic microbes was non-significant in this group. The adverse events (AEs) were in mild form, and the proportion of patients with AEs differed non-significantly between two groups.</div></div><div><h3>Conclusion</h3><div>The IP supplementation along with SOC significantly improved the GUT micro flora, and improved the overall quality of life of CKD patients. This treatment combination can be practiced for effective patient management.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 2","pages":"Article 100992"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143520137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of Ayurvedic treatment given to cancer patients in the prevention of COVID-19 – A Retrospective Cohort Study at Integrated Cancer Treatment and Research Centre, Wagholi","authors":"Sadanand Sardeshmukh, Vineeta Deshmukh, Vidya Gupta, Vasanti Godse, Shweta Gujar, Swapna Kulkarni, Sneha Dalvi, Nilambari Sardeshmukh, Bhagyashree Sardeshmukh, Sushama Bhuvad, Sandeep Chavan, Vinita Awalkanthe, Shrinivas Datar, Anita Shingte, Abhishek Salunkhe, Amruta Salunkhe, Sneha Nabar, Dhananjay Deshpande, Trupti Dafare","doi":"10.1016/j.jaim.2024.101045","DOIUrl":"10.1016/j.jaim.2024.101045","url":null,"abstract":"<div><h3>Background</h3><div>Cancer patients are considered to have a higher risk of developing severe Coronavirus Disease 2019 (COVID-19) and a higher mortality rate. Moreover, poor prognosis observed in them is associated with multiple co-morbidities. Ayurveda can prove to be effective in preventing COVID-19 as well as improving clinical outcomes against COVID-19 in cancer patients.</div></div><div><h3>Objectives</h3><div>To evaluate the effect of Ayurvedic treatments given to cancer patients as also a preventive modality against COVID-19 infections.</div></div><div><h3>Methods</h3><div>700 cancer patients were enrolled in the study. The demographic information regarding their age, sex, organs involved, stage, pre-existing comorbidities, Karnofsky score, addictions, undergoing conventional cancer treatment, type of conventional treatment, and duration of Ayurvedic cancer treatment was collected from the institutional records. These patients were interviewed telephonically or in person to obtain information related to their COVID-19 status from March 2020 to Sep 2021, which included a) whether they were affected with COVID-19 or not, b) If affected, the severity of COVID-19 symptoms, c) vaccination status, d) mortality, and e) if in contact with relative affected by COVID-19.</div></div><div><h3>Results</h3><div>The surveyed cohort had 56 years as the median age, more female patients, Karnofsky score between 80 and 100, and hypertension as well as diabetes as major co-morbidities. During the 1st and 2nd waves, 34 (4.85%) and 65 patients (10.09 %) were COVID-19 positive while 4.91 % and 11.11% of patients with addictions were covid positive, respectively, the rest remained unaffected.</div><div>There was no specific trend in % of COVID-19-positive cancer patients concerning stage, but those with stage IV undergoing conventional treatment showed increased prevalence (p < 0.001). Prolonged Ayurvedic treatment exhibited a decreasing trend in % COVID-19 positive patients, which is highly significant (p < 0.001). Specifically, those undergoing conventional therapy, and also received Ayurvedic treatment simultaneously for more than 3 years remained unaffected by COVID-19, which was statistically significant in both waves (p < 0.001).</div></div><div><h3>Conclusion</h3><div>Ayurvedic treatments given to cancer patients are effective in preventing COVID-19 infections in these patients.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 2","pages":"Article 101045"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143549342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"AyurCeL: A comprehensive ayurveda clinical E-learning platform","authors":"Rammanohar Puthiyedath , Sushma Naranappa Salethoor , Shyamasundaran Kulangara , Raghu Raman , Nagarajan Chockan , Anupama Kizhakkeveettil , Prema Nedungadi","doi":"10.1016/j.jaim.2024.101107","DOIUrl":"10.1016/j.jaim.2024.101107","url":null,"abstract":"<div><div>Ayurveda, an ancient holistic medicinal system, has sustained its relevance over millennia and continues to be practised extensively in India. However, challenges persist in clinical expertise among Ayurvedic practitioners, often due to limited clinical exposure during their academic journey. The Ayurveda Clinical E-Learning Portal (AyurCeL) aims to bridge the gap in clinical expertise among Ayurvedic practitioners by providing a digital platform for sharing well-documented clinical case studies. This paper outlines the objectives, architecture, and comprehensive modules of AyurCeL, emphasizing its role in facilitating continuous clinical learning and improving the quality of Ayurvedic practice. AyurCeL offers a multi-faceted approach to learning, featuring a clinical case repository, Ayurveda case report preprint archive and post-publication review tool. By merging traditional insights with contemporary technology, AyurCeL not only preserves Ayurveda's profound legacy but also enhances its relevance and reach in today's medical landscape.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 2","pages":"Article 101107"},"PeriodicalIF":1.7,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143403288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In pursuit of evidence: A need to transform Ayurvedic education","authors":"Sruthi G, Megha","doi":"10.1016/j.jaim.2024.101110","DOIUrl":"10.1016/j.jaim.2024.101110","url":null,"abstract":"<div><div>There is a loud call nationally and internationally to strengthen the evidence base for traditional medicine. Ayurveda, like other traditional systems, is often criticized for its lack of evidence upto the standard expected for modern day healthcare drugs and practices. This gap in evidence has led to Ayurveda being viewed as inferior to biomedicine. Therefore, producing high-quality evidence is essential not only for the credibility of Ayurveda but also to elevate its inclusion in standard of care practices globally. Yet, how can this evidence be generated if Ayurvedic researchers and practitioners are not formally taught about the advantages and means of evidence synthesis? The prevailing research culture in Ayurveda largely emphasizes validating ayurvedic formulations by substituting them into well-established clinical protocols for modern disease descriptors, rather than focusing on hypothesis-driven research using ayurvedic vocabulary. We argue that this arises in part from an outdated curriculum, poorly trained teachers, insufficient investment in research infrastructure at teaching colleges, and a paucity of policies to encourage cross-disciplinary learning. To address these gaps, we propose a comprehensive transformation of Ayurvedic education by including biomedical credit courses into the curriculum, practical internships to provide hands-on-experience, recruitment of teachers with biomedical expertise and funds to upgrade Ayurveda colleges. These ideas will help develop a cohort of Ayurveda graduates who are not only familiar with modern biomedicine, but also have the fundamental knowledge to develop, and test new ideas. India can emerge as a global leader in the area of integrative medicine, with its repository of several indigenous medical systems, and talented human capital in biomedical sciences. It is time we take the plunge.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 2","pages":"Article 101110"},"PeriodicalIF":1.7,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143350746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Research status of traditional & complementary medicine systems across the world","authors":"Vedvati Bhapkar , Vallari Nisargand , Pawankumar Godatwar , Supriya Bhalerao","doi":"10.1016/j.jaim.2024.101078","DOIUrl":"10.1016/j.jaim.2024.101078","url":null,"abstract":"<div><h3>Background</h3><div>Despite strong presence of biomedicine, traditional and complementary medicine (T & CM) systems have sustained with their multidimensional connect with people. However, their scientific acceptance and mainstreaming falls short due to inadequacies in research. Also, available reports in this regard scarcely focus on their individuality and present them as a consolidated entity.</div></div><div><h3>Objectives</h3><div>The present study was carried out to elucidate individual research status of certain WHO- acknowledged T & CM systems in a customized framework of indirect indicators.</div></div><div><h3>Material and methods</h3><div>The research status of selected systems was assessed on basis of quantitative indicators viz., research dissemination outcomes concerned with scientific documents and researchers, contribution in COVID-19 prevention and management, and patents profile.</div></div><div><h3>Results</h3><div>Systems such as Traditional Chinese Medicine and Acupuncture fare better than most others. The number of documents in multidisciplinary SCOPUS database was larger than those in PubMed, a healthcare database for almost all systems. Out of 28 lead authors, half belonged to developed countries, viz., USA and Germany. Highest citation count was recorded for TCM (n = 2238). Of the 105 journals analyzed, 40 were not dedicated to specific T & CM system. Most number of discretely dedicated journals (n = 20) mentioned TCM as primary scope. Cochrane systematic reviews (n = 142) and protocols (n = 33) were highest for Acupuncture, while many systems had zero presence. Maximum COVID-19 related clinical studies were registered for TCM (n = 335), followed by Ayurveda (n = 112). TCM related patents were also highest among all.</div></div><div><h3>Conclusion</h3><div>There is a huge variation in the research status of different T & CM systems. The stakeholders of these systems need to establish a strong evidence base at par with biomedicine. United efforts at global level through organizations such as WHO-Global Traditional Medicine Centre (GTMC) might be helpful in this regard.</div></div>","PeriodicalId":15150,"journal":{"name":"Journal of Ayurveda and Integrative Medicine","volume":"16 2","pages":"Article 101078"},"PeriodicalIF":1.7,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143350745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}