A 14 years overall survival of a patient with stage IV carcinoma of cervix with lung metastasis - A case report of Ayurveda based integrative approach

IF 1.7 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE
Sadanand Prabhakar Sardeshmukh, Vineeta Vasant Deshmukh, Arvind Vishnu Kulkarni, Shweta Rakesh Gujar, Nilambari Sushrut Sardeshmukh, Bhagyashree Sukumar Sardeshmukh, Vinita Sanjog Awalkanthe, Suchita Kishor Shiraskar, Dhananjay Ravindra Deshpande, Sandeep Bhagwan Chavan, Vidya Shrikant Gupta
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Abstract

Background

Carcinoma of the cervix is a leading cause of cancer-related mortality in women. The commonest metastatic site in cervical cancers is lung. Prognosis of cervical cancer with lung metastasis is very poor.

Case presentation

The present patient, an inhabitant of rural India, was diagnosed with squamous cell carcinoma of cervix in stage III, grade II in July 2011. She underwent radical course of pelvic radiotherapy along with concurrent weekly chemotherapy, also received two sittings of brachytherapy after completing external beam radiotherapy. Before initiating radical radiotherapy in 2011, she received a combination of personalised/tailored herbo-mineral Ayurvedic medicines for 1 year and 10 months with an aim to minimise the side effects of radiotherapy. After completing radiotherapy, she was treated with a set of Ayurvedic medicines mainly to boost her immunity and to prevent recurrence. She was asymptomatic with good quality of life; all her radiological and biochemical parameters were within normal range till 2016. During her routine periodic investigations in March 2016, X-ray chest revealed nodular opacity on peripheral aspect of left mid zone. Patient underwent CT guided left lung mass biopsy which confirmed the diagnosis as squamous cell carcinoma of left lung (non-small cell type). At this point, the primary cancer was metastasized to lung and upgraded from stage III to stage IV. For this, she was treated with palliative course of radiotherapy. She has been taking regularly oral Ayurvedic medicines till date.

Conclusion

Progression free survival of six years and overall survival of 14 years along with exceptional good quality of life has been observed in Stage IV cervical cancer patient with lung metastasis. This has been achieved by integrative approach of conventional cancer treatment of radiotherapy and personalised adjunct Ayurvedic treatment containing combination of oral herbo-mineral metallic medicines.
4期宫颈癌伴肺转移患者14年总生存率-阿育吠陀综合治疗1例报告
背景:宫颈癌是女性癌症相关死亡的主要原因。宫颈癌最常见的转移部位是肺。宫颈癌合并肺转移的预后很差。病例介绍本例患者是印度农村居民,于2011年7月被诊断为宫颈鳞状细胞癌III期,II级。患者行盆腔放疗根治疗程,同时每周化疗,并在完成外束放疗后接受2次近距离治疗。在2011年开始根治性放射治疗之前,她接受了为期1年零10个月的个性化/定制草药矿物阿育吠陀药物组合治疗,目的是尽量减少放射治疗的副作用。在完成放疗后,她接受了一套阿育吠陀药物的治疗,主要是为了提高她的免疫力,防止复发。患者无症状,生活质量良好;截至2016年,放射学及生化指标均在正常范围内。2016年3月例行定期检查,胸部x线示左侧中区外周结节性不透明。患者行CT引导下左肺肿块活检,确诊为左肺鳞状细胞癌(非小细胞型)。此时,原发肿瘤转移至肺部,由III期升级至IV期。为此,患者接受姑息性放疗。到目前为止,她一直定期服用口服阿育吠陀药物。结论4期宫颈癌伴肺转移患者无进展生存期为6年,总生存期为14年,生活质量良好。这是通过传统癌症放射治疗和个性化辅助阿育吠陀治疗的综合方法实现的,其中包括口服草药矿物金属药物的组合。
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来源期刊
Journal of Ayurveda and Integrative Medicine
Journal of Ayurveda and Integrative Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
4.70
自引率
12.50%
发文量
136
审稿时长
30 weeks
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