Journal of Back and Musculoskeletal Rehabilitation最新文献

{"title":"Palpation-based scapular dyskinesis test: Inter-and intra-rater reliability and clinical advantages.","authors":"Jian Kim, Young Kyun Kim","doi":"10.1177/10538127241308969","DOIUrl":"10.1177/10538127241308969","url":null,"abstract":"<p><p>BackgroundThe Scapular Dyskinesis Test (SDT) is typically conducted using either real-time visual observation or video analysis. However, factors such as restricted shoulder mobility, higher body mass index (BMI), patient-centred care, and cultural considerations may impact the reliability of SDT results. Palpation offers an alternative approach that addresses these limitations by providing additional tactile information on joint function and dysfunction.ObjectiveThis study aimed to evaluate the reliability and potential benefits of the palpation-based SDT.MethodsVideotaped, real-time visual observation, and palpation-based SDTs were conducted on 55 patients to assess the reliability and potential advantages of the palpation technique.ResultsThe inter-rater reliability of the palpation-based SDT was almost perfect (<i>k </i>= 0.82), while intra-rater reliability was similarly high (<i>k </i>= 0.97). Additionally, eight patients diagnosed with scapular dyskinesis (SD) were found to have Scapular Snapping Syndrome (SSS).ConclusionThe palpation-based SDT demonstrated superior inter-rater reliability compared to video analysis and real-time visual observation, with almost perfect reliability (<i>k </i>= 0.82). This method is particularly beneficial for patients with high or low BMI, those unable to remove clothing, and may be useful for detecting SSS. The findings suggest that palpation SDT is an effective tool for assessing scapular dyskinesis in various clinical settings.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"616-623"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous functional spinal unit cementoplasty <i>versus</i> percutaneous kyphoplasty for severe osteoporotic vertebral compression fracture complicated with endplate-disc complex injury: A retrospective case-control study.","authors":"Yuming Yang, Ben Zhao, Youdi Xue, Weixiang Dai","doi":"10.3233/BMR-240145","DOIUrl":"10.3233/BMR-240145","url":null,"abstract":"<p><p>BACKGROUNDSevere osteoporotic vertebral compression fracture (SOVCF) is frequently complicated by endplatedisc complex (EDC) injury. While percutaneous kyphoplasty (PKP) can offer rapid analgesia and facilitate early activity, it does not restore vertebral height and may result in intervertebral leakage and untreated EDC injury.OBJECTIVEThis study aimed to evaluate the clinical outcomes of percutaneous functional spinal unit cementoplasty (PFSUP) for SOVCF complicated by EDC injury and compare its clinical and imaging outcomes with PKP.METHODSThis was a retrospective case-control study. Patients with SOVCF complicated with EDC injury between January 1, 2018, and December 31, 2019, were recruited and assigned to the PKP group and PFSUP group based on their treatment procedures Back pain was evaluated using the visual analog scale (VAS) and daily life activities were assessed using the Oswestry disability index (ODI). X-rays were employed to observe the presence and location of cement leakage, as well as to measure the sagittal vertical axis (SVA) and local kyphosis angle (LKA). Loss of correction was calculated by subtracting the LKA after surgery from that at the final follow-up visit Subsequent vertebral fracture (SVF) was confirmed using the Genant semi-quantitative method and/or MRI.RESULTSA total of 64 patients were included in this study. Among them 41 cases were assigned to the PKP group (28 females, 74.8 years on average), while the remaining 23 cases were assigned to the PFSUP group (15 females, 76.3 years on average). All surgical interventions were successfully completed without major complications. Compared to the PKP group, the PFSUP group had longer operation time (70.28 ± 11.44 vs 44.5 ± 10.12, <i>P</i>< 0.001) higher frequencies of radiation exposure (97.6 ± 19.85 vs 38.6 ± 9.53, <i>P</i>< 0.001), and a lower cement leakage rate (26.1% vs. 41.5%, <i>P</i>< 0.001). One day after surgery and at the final follow-up the PFSUP group had lower VAS and ODI scores, as well as lower LKA and Sva values compared with the PKP group (all <i>P</i>< .001). At the final follow-up visit, the PFSUP group demonstrated a lower loss of correction (4.38 ± 2.71 vs. 10.19 ± 3.41 <i>P</i>< 0.001) and a lower SVF rate compared to the PKP group (21.7% vs. 31.7%, <i>P</i>< 0.001).CONCLUSIONPFSUP outperformed PKP in alleviating pain restoring and maintaining sagittal balance, and lowering the incidence of cement leakage and SVF for SOVCF with EDC injury However, PFSUP was associated with longer operation time and high radiation exposure frequencies.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"453-461"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of instrument-assisted manipulation and mobilization with movement in chronic non-specific low back pain: A randomized controlled trial.","authors":"Erkan Erol, Mustafa Burak, Bülent Elbasan","doi":"10.1177/10538127241309343","DOIUrl":"10.1177/10538127241309343","url":null,"abstract":"<p><p>BackgroundLow back pain is the third most reported complaint after headache and chronic fatigue, and more than 80% of the population will experience low back pain at some point in their lives.ObjectıveWe conducted this study to investigate the effects of instrument-assisted manipulation (IAM) and mobilization with movement (MWM) on joint range of motion (ROM), pain, proprioception, endurance, back awareness, and disability in individuals with chronic nonspecific low back pain (CNSLBP).Methods51 participants with CNSLBP were randomized to one of three groups: (1) MWM; (2) IAM; or (3) core exercise. Joint ROM, pain, proprioception, endurance, back awareness, and disability were assessed at baseline, week 2 and 6.ResultsJoint ROM and activity pain scores increased in all groups (p < 0.05). Both activity and resting pain improved in the MWM group (p < 0.001; p = 0.004). Most measures related to proprioception improved in the MWM group (p = 0.005; p = 0.016; p = 0.016). Endurance increased in all groups, but the flexor endurance increase was higher in the MWM group (p < 0.05). Back awareness and disability increased in all groups (p < 0.05), but disability increased most in MWM group (p = 0.022).ConclusıonsMWM could effectively improve pain, proprioception, endurance, and disability.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"640-650"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical assessment of lumbar mobility: Height of the lumbar spine and localization of L1 by ultrasound.","authors":"D Jacquemin, C Demoulin, G Dorban, F Tubez, M Vanderthommen","doi":"10.1177/10538127241310594","DOIUrl":"10.1177/10538127241310594","url":null,"abstract":"<p><p>BackgroundVarious tools for clinical assessment of lumbar mobility in the sagittal plane coexist. Their validity has been called into question in particular because of their fixed distances between their skin markers whatever the height of the subject.ObjectiveTo measure the distance between the lower margin of the Postero Superior Iliac Spines (PSIS) and the middle of the L1 spinous process and to analyze the characteristics that influence it. To check whether these new skin marks could be more reliable for developing a new clinical assessment tool for lumbar mobility.MethodThe distance between the lower margin of the PSIS and the L1, located by ultrasound, was taken in the standing position and analyzed on 200 participants.ResultsThe mean PSIS-L1 distance was 13.3 ± 1.8 cm, influenced mainly by standing height. A ratio or the regression line equation, based on the relationship between standing height and PSIS-L1, were highlighted.ConclusionsThe actual mode of placement of skin markers for the clinical assessment tools to evaluate lumbar mobility is not valid. The PSIS-L1/standing height ratio or the regression equation are the most effective ways for predicting the location of the upper skin marker (L1) for developing a new tool.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"633-639"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of electroacupuncture for early ankle osteoarthritis: A randomized controlled trial using three-dimensional gait analysis.","authors":"Cai Jiang, Libin Xia, Hai Li, Xiaohua Ke, Sicheng Li, Jiaqi Wang, Zizhe Yao, Dunbing Huang, Zhonghua Lin","doi":"10.1177/10538127241308216","DOIUrl":"10.1177/10538127241308216","url":null,"abstract":"<p><p>BackgroundAnkle osteoarthritis (AOA) is a prevalent condition that affects joint function, often leading to pain, inflammation, and impaired mobility, significantly impacting patients' quality of life.ObjectiveThis study explores the effects of electroacupuncture treatment on clinical outcomes and gait characteristics in patients with ankle osteoarthritis (AOA).MethodsA total of 78 patients with AOA were randomly divided into a experiment group and a control group. The control group was treated with strength training, and the experiment group was additionally treated with electroacupuncture. The Ankle Osteoarthritis Scale (AOS), American Foot and Ankle Society's Ankle and Hindfoot Scale (AOFAS-AHS), and the 3D Motion Analysis System were used before and after the intervention to assess the clinical outcomes and changes in kinematic parameters in the AOA patients before and after therapy.ResultsAfter treatment, the differences in intra-group comparisons and inter-group comparisons of AOS scores, AOFAS-AHS scores, stride length, stride length, single-support phase, and gait variable scores (GVS) of ankle dorsiflexion-plantarflexion of the patients in the experiment group were statistically significant; the differences in inter-group comparisons of GVS scores of hip rotation of the patients in the experiment group were statistically significant; and the differences in the gait profile scores (GPS) and gait deviation indices of the patients in the experiment group were statistically significant. The differences in the intra-group comparisons were statistically significant. The within-group comparisons of AOS score, AOFAS-AHS score, GPS score and GVS score of ankle dorsiflexion-plantarflexion were statistically significant in the control group patients.ConclusionsElectroacupuncture has shown promise as an adjunctive therapy for patients with AOA, offering a more holistic rehabilitation strategy. By improving joint mobility and optimizing gait mechanics, electroacupuncture can effectively reduce pain, facilitate the restoration of normal gait patterns, and enhance patients' overall quality of life.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"593-604"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomechanical characteristics and neuromuscular action control mechanism of single-dual-task walking-conversion training in stroke patients.","authors":"Yilan Sheng, Jia Han","doi":"10.1177/10538127241308215","DOIUrl":"10.1177/10538127241308215","url":null,"abstract":"<p><p>Background and purposeThis study aimed to explore the biomechanical characteristics of patients with stroke and neuromuscular action control mechanisms in single-dual-task walking-conversion training.Materials and methodsPatients with stroke from four centers were enrolled and randomly divided into the cognitive combined treadmill-walking and exercise combined treadmill-walking groups (n = 30 per group). The gait spatiotemporal parameters, walking function, and fall risk of the two experimental groups were compared before and after 4 and 6 weeks of training. Surface electromyography (sEMG) and functional near-infrared spectroscopy (fNIRS) were performed to analyze neuromuscular action control mechanisms in different task phases.ResultsAfter 6 weeks of training, the gait spatiotemporal parameters, walking function, integral electromyogram (iEMG) values, and root mean square (RMS) of the affected lower limb muscles of the two experimental groups significantly improved (<i>P</i> < 0.01), while the fall risk was reduced (<i>P</i> < 0.01). fNIRS analysis showed that in both the single- and dual-task phases, HbO signal concentrations in the brain functional regions of the two experimental groups significantly increased after training (<i>P</i> < 0.01). These indicators were not significantly different between the two experimental groups after 6 weeks of training (<i>P</i> > 0.05). In addition, during the dual-task phase, the blood oxygen signal concentrations and functional connectivity in the functional brain regions of the two experimental groups were lower than those of healthy controls.ConclusionCognitive or motor tasks combined with treadmill-walking training can promote the recovery of physical function in patients with stroke.<b>Clinical trial registration:</b> This study was registered in the Chinese Clinical Trial Registry (ChiCTR; registration number: ChiCTR2200060864).</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"576-592"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive functional therapy for lower back pain: A meta-analytical assessment of pain and disability outcomes in randomized controlled trials.","authors":"Mahmoud Kandeel, Mohamed A Morsy, Khalid M Al Khodair, Sameer Alhojaily","doi":"10.3233/BMR-240230","DOIUrl":"10.3233/BMR-240230","url":null,"abstract":"<p><p>BackgroundCognitive functional therapy (CFT) aims to address low back pain (LBP) comprehensively by considering physical, psychological, and social factors.ObjectiveThe objective was to evaluate the effectiveness of CFT in reducing pain and disability in individuals with LBP over various time intervals.MethodA comprehensive literature search was conducted to identify relevant randomized controlled trials (RCTs) assessing the effects of CFT on LBP.ResultsIn this study, 1510 records were initially identified, and 7 studies were included in the analysis. Disability scores were significantly reduced after CFT had been applied for 6 to 8 weeks (SMD <math><mo>=</mo></math><math><mo>-</mo></math>0.46, 95% CI [<math><mo>-</mo></math>0.74, <math><mo>-</mo></math>0.19]), 12 weeks to 3 months (SMD <math><mo>=</mo></math><math><mo>-</mo></math>0.54, 95% CI [<math><mo>-</mo></math>0.72, <math><mo>-</mo></math>0.36]), 6 months (MD <math><mo>=</mo></math><math><mo>-</mo></math>5.82, 95% CI [<math><mo>-</mo></math>9.82, <math><mo>-</mo></math>1.82]), and 12 months (SMD <math><mo>=</mo></math><math><mo>-</mo></math>0.4, 95% CI [<math><mo>-</mo></math>0.55, <math><mo>-</mo></math>0.26]). There were also significant reductions in pain scores observed after 12 weeks to 3 months (SMD <math><mo>=</mo></math><math><mo>-</mo></math>0.49, 95% CI [<math><mo>-</mo></math>0.68, <math><mo>-</mo></math>0.3]), 6 months (MD <math><mo>=</mo></math><math><mo>-</mo></math>0.75, 95% CI [<math><mo>-</mo></math>1.5, <math><mo>-</mo></math>0.0001]), and 12 months (SMD <math><mo>=</mo></math><math><mo>-</mo></math>0.27, 95% CI [<math><mo>-</mo></math>0.42, <math><mo>-</mo></math>0.12]).ConclusionCFT showed potential for improving disability scores for individuals with LBP across various time intervals. However, its impacts on pain scores varied.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"462-472"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142287970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strengthening football: The role of the nordic hamstring exercise in preventing hamstring injuries.","authors":"Roberto Tedeschi, Giacomo Farì, Federica Giorgi, Daniela Platano, Lisa Berti, Andrea Bernetti, Danilo Donati","doi":"10.1177/10538127251326736","DOIUrl":"https://doi.org/10.1177/10538127251326736","url":null,"abstract":"<p><p>BackgroundHamstring strain injuries (HSIs) are among the most common injuries in football, causing significant time-loss and impacting player performance. Despite various preventive strategies, the incidence of HSIs remains high, necessitating evidence-based approaches to reduce injury rates.ObjectiveThis scoping review aims to evaluate the effectiveness of the Nordic Hamstring Exercise (NHE) in reducing the incidence and recurrence of HSIs in football players and to provide practical recommendations for its implementation.MethodsA comprehensive literature search was conducted in PubMed, Scopus, Web of Science, PEDro, and the Cochrane Library. Randomized controlled trials (RCTs) focusing on NHE interventions for football players were included. The primary outcomes were injury incidence, recurrence, and compliance with NHE programs.ResultsThe review found that NHE significantly reduces the incidence of new hamstring injuries by up to 60% and recurrent injuries by up to 85%. Players performing NHE demonstrated a 35% increase in eccentric hamstring strength. Compliance with NHE programs was a critical factor in achieving these outcomes, with higher adherence rates leading to better preventive effects.ConclusionsThe Nordic Hamstring Exercise is an effective, evidence-based intervention for preventing hamstring injuries in football. Its integration into regular training programs, combined with education to improve compliance, can significantly reduce injury rates and enhance player performance. Future research should focus on standardizing protocols and exploring long-term outcomes.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"10538127251326736"},"PeriodicalIF":1.4,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Criteria for knee flexion range of motion and quadriceps strength to ascend and descend stairs 1 year after bilateral total knee arthroplasty: A cross-sectional study.","authors":"Keigo Nanjo, Takashi Ikeda, Ryutaku Kaneyama, Hiroyuki Okuyama, Tomoko Sakai, Tetsuya Jinno","doi":"10.1177/10538127251323980","DOIUrl":"https://doi.org/10.1177/10538127251323980","url":null,"abstract":"<p><p>BackgroundStair ascent/descent pose significant challenges after total knee arthroplasty (TKA); however, the exact knee flexion range of motion (ROM) and quadriceps strength requirements remain unclear.ObjectiveTo establish criteria for knee flexion ROM and quadriceps strength to determine independence in stair ascent/descent and evaluate the accuracy of the combination of these factors in patients with bilateral TKA.MethodsPatients with bilateral TKA were cross-sectionally assessed at 1 year postoperatively for independence in stair ascent/descent. Receiver operating characteristic curves provided cutoff values for knee flexion ROM and quadriceps strength. The area under the curves (AUC) of each factor and logistic regression models including both factors were evaluated.ResultsEighty-two participants were included. Fifty-eight participants could independently ascend and 52 could descend stairs, with equal cutoff values for both: 121° for knee flexion ROM (AUC: 0.66 and 0.67) and 1.09 Nm/kg for quadriceps strength (AUC: 0.70 and 0.73). Logistic regression models produced AUCs of 0.73 and 0.76 for ascent and descent, respectively.ConclusionsA quadriceps strength of 1.09 Nm/kg is a useful cutoff for independent stair ascent/descent, but combining it with knee flexion ROM did not enhance accuracy. Other functions such as coordination of the knee or other joints may influence stair performance post-TKA.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"10538127251323980"},"PeriodicalIF":1.4,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between sarcopenia and intervertebral disc degeneration: A bidirectional two-sample Mendelian randomization.","authors":"Jiawen Guo, Qiuyue Ding, Li Sun","doi":"10.1177/10538127251318926","DOIUrl":"https://doi.org/10.1177/10538127251318926","url":null,"abstract":"<p><p>BackgroundSarcopenia (SP) and Intervertebral Disc Degeneration (IVDD) are common age-related diseases that significantly affect the physical and mental health of patients. A substantial body of evidence suggests a potential association between SP and IVDD. However, the causal relationship between SP and IVDD remains uncertain.ObjectivesThis study aimed to determine whether the association between SP and IVDD is causal by employing Mendelian randomization (MR) analysis.MethodsGenome-wide association study (GWAS) data related to SP (measured by muscle lean mass, left- and right-hand grip strength, and walking speed) and IVDD were obtained from the UK Biobank and FinnGen. To investigate the causal relationship between SP and IVDD, three MR analysis methods were employed, primarily focusing on the Inverse-Variance Weighted (IVW) approach. The robustness of causal effects was ensured through multiple methods: Instrumental Variables (IVs) were evaluated using F-values; heterogeneity was assessed using Cochran's Q; horizontal pleiotropy was evaluated using MR Egger regression; and outliers was detected using MR-PRESSO and the leave-one-out method.ResultsThe analysis indicates a potential causal relationship between appendicular lean mass (ALM) and the risk of IVDD (OR = 0.89, 95% CI: 0.809-0.98; P < 0.05). Similarly, left-hand grip strength shows a potential causal relationship with IVDD risk (OR = 1.52, 95% CI:1.08-2.14; P < 0.05), as does right-hand grip strength (OR = 1.50, 95% CI:1.09-2.07; P < 0.05). Additionally, a potential causal relationship is observed between IVDD and walking speed (OR = 0.99, 95% CI:0.97-1.00; P < 0.05).ConclusionThe findings suggest that ALM may serve as a protective factor against IVDD, while left- and right-hand grip strength may be risk factors for the development of IVDD. Furthermore, IVDD appears to be a risk factor associated with reduced walking speed. Further research is necessary to elucidate the underlying mechanisms of these associations.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"10538127251318926"},"PeriodicalIF":1.4,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}