{"title":"Blood flow restriction improves lower limb muscle function in adults with musculoskeletal disorders: A systematic review and meta-analysis.","authors":"Yineng Tan, Jianyu Gan, Leyi Jiang, Huakun Zheng, Yundi Zhang, Limingfei Zhou, Dapeng Bao, Junhong Zhou","doi":"10.1177/10538127261485421","DOIUrl":"https://doi.org/10.1177/10538127261485421","url":null,"abstract":"<p><p>BackgroundLow-intensity resistance training with blood flow restriction (LIRT-BFR) may improve musculoskeletal function, but its effects in musculoskeletal disorders remain uncertain.ObjectiveTo examine LIRT-BFR effects on lower-limb muscle size, strength, and mobility in musculoskeletal disorders, and explore potential effect modifiers.MethodsFive databases (PubMed, Cochrane Library, Web of Science, SPORTDiscus, EMBASE) were searched from inception to November 20, 2025. Randomized controlled trials involving adults with musculoskeletal disorders comparing LIRT-BFR to control or active interventions were included. Two reviewers independently screened studies and extracted data. Random-effects meta-analyses were conducted, and certainty of evidence was assessed using the GRADE approach.ResultsSixteen trials (638 participants) were included. Compared with non-exercise controls, LIRT-BFR significantly improved lower-limb muscle strength (g = 1.20, 95% CI [0.54, 1.87]), muscle size (g = 1.65, 95% CI [0.88, 2.43]), and lower-limb functionality (TUG: g = -0.73, 95% CI [-1.21, -0.24]; TST: g = 1.85, 95% CI [1.19, 2.52]). Compared with LIRT alone, LIRT-BFR improved muscle strength (g = 0.56, 95% CI 0.08-1.04) and timed-stands performance (g = 0.86, 95% CI 0.44-1.28). No advantage over MHIRT was observed for muscle strength (g = -0.10, 95% CI -0.48 to 0.28) or timed-stands performance (g = -0.50, 95% CI -1.01 to 0.01). Exploratory analyses showed favorable point estimates for 12-18 sessions and non-failure protocols. Certainty of evidence ranged from moderate to very low across comparator-specific outcomes.ConclusionsLIRT-BFR improves lower-limb muscle and functional outcomes relative to non-exercise controls and may provide additional benefits over LIRT for selected outcomes. No advantage over MHIRT was identified. Clinical heterogeneity, wide prediction intervals, and risk of bias warrant cautious interpretation.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"10538127261485421"},"PeriodicalIF":1.6,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acute responses to local tibialis anterior fatigue: Effects on dynamic balance and muscle mechanical properties.","authors":"Ali Ilez, Yasemin Şahbaz, Nergiz Batur","doi":"10.1177/10538127261488179","DOIUrl":"https://doi.org/10.1177/10538127261488179","url":null,"abstract":"<p><p>BackgroundLocal muscle fatigue can influence the neural functional mechanisms and intrinsic mechanical properties of the muscle. Considering the importance of the tibialis anterior (TA) muscle during walking and upright standing positions, the primary aim of this study is to understand how induced local muscle fatigue affects both dynamic balance and changes in muscle mechanical properties.MethodsThirty healthy participants (mean age: 21.83 ± 1.41 years) were included in the study. Muscle mechanical properties of the dominant TA were assessed using MyotonPro, and dynamic balance was evaluated bilaterally with the Modified Star Excursion Balance Test (mSEBT) before and after the fatigue protocol. The fatigue protocol was applied bilaterally to ankle dorsiflexor muscle muscles and consisted of repeated 30-s isometric dorsiflexion contractions followed by 15-s rest intervals, continued until participants reported a Borg Rating of Perceived Exertion score of 7 or higher.ResultFollowing the fatigue protocol, a significant improvement was observed in left mSEBT and right mSEBT scores (<i>p</i> < 0.05), except in the anterior direction, where no significant change was detected. Regarding muscle mechanical properties, stiffness decreased, but this change was not statistically significant (p = 0.06), whereas relaxation time and creep significantly increased (p < 0.05).ConclusionLocalized ankle dorsiflexor muscle fatigue acutely altered both dynamic balance and muscle mechanical properties. The apparent improvement in mSEBT scores likely reflects short-term neuromuscular compensation rather than genuine performance enhancement. Decreased stiffness and increased relaxation indicate transient adaptations in the muscle's passive behavior.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"10538127261488179"},"PeriodicalIF":1.6,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernanda de Souza Cardoso, Lidiane Lima Florencio, Andréa Licre Pessina Gasparini, Denise Martineli Rossi
{"title":"Do neck and shoulder disabilities differ between isolated and associated symptom groups?: A cross-sectional study.","authors":"Fernanda de Souza Cardoso, Lidiane Lima Florencio, Andréa Licre Pessina Gasparini, Denise Martineli Rossi","doi":"10.1177/10538127261483800","DOIUrl":"https://doi.org/10.1177/10538127261483800","url":null,"abstract":"<p><p>IntroductionNeck and shoulder symptoms are common musculoskeletal complaints that may occur independently or coexist, with the cervical region potentially contributing to shoulder pain.ObjectiveTo compare neck and shoulder disability and sex distribution among patients with isolated and associated symptoms in the neck and shoulder. Moreover, investigate the association between neck and shoulder disability in each symptom group.MethodsThis cross-sectional study evaluated 157 participants with self-reported shoulder pain (n = 35), neck pain (n = 27) and associated shoulder and neck pain (n = 95). Shoulder Pain and Disability Index (SPADI) and Neck Pain Disability Index (NDI) were applied. Kruskal-Wallis, Chi-Squared and Spearman correlation tests were used.ResultsThe associated symptoms group showed a higher prevalence of female sex (chi-squared = 8.62, <i>p</i> = 0.01) and longer symptom duration (<i>p</i> = 0.001). Shoulder disability was higher in the shoulder pain (<i>p</i> = 0.001) and associated symptoms groups (<i>p</i> = 0.001). Neck disability was higher in the associated symptoms and neck pain group. A moderate positive correlation between SPADI and NDI was observed for the shoulder pain group (<i>p</i> = 0.02, r = 0.38) and associated symptoms (<i>p</i> = 0.001, r = 0.57), but not for the neck pain (<i>p</i> = 0.15, r = 0.28).ConclusionAssociated symptoms were associated with greater disability. Shoulder disability was higher when shoulder pain was present, while neck disability was most pronounced in the associated symptoms group. The moderate correlations between SPADI and NDI suggest an association between shoulder and neck impairment that does not occur in isolated neck pain group.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"10538127261483800"},"PeriodicalIF":1.6,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Junhui Zhu, Yan Bu, Zhongming Song, Ling Xu, Hongxiang Zhang
{"title":"Association between electromyographic and neurophysiological indices and functional and function-related outcomes after lower-limb injury: A three-level meta-analysis.","authors":"Junhui Zhu, Yan Bu, Zhongming Song, Ling Xu, Hongxiang Zhang","doi":"10.1177/10538127261488143","DOIUrl":"https://doi.org/10.1177/10538127261488143","url":null,"abstract":"<p><p>BackgroundLower-limb sports injuries may leave persistent neuromuscular deficits that conventional functional measures do not fully capture. Surface electromyography (sEMG) and related neurophysiological indices may provide complementary information, but their associations with functional and function-related outcomes remain uncertain.MethodsFollowing PRISMA guidance (PROSPERO: CRD420261416860), PubMed, Web of Science, Embase, the Cochrane Library, and CNKI were searched from inception to 2 May 2026. Eligible studies reported correlations between EMG/neurophysiological indices and functional or function-related outcomes after lower-limb injury. Methodological quality was assessed using the JBI checklist. A three-level random-effects model pooled Fisher-transformed correlations while accounting for effect sizes nested within studies. Subgroup analyses were considered exploratory because few independent studies were available.ResultsSix studies contributed 14 effect sizes from 135 participants. The pooled association was moderate and positive (Fisher's Z = 0.536, 95% CI 0.305-0.766, p = 0.003; r = 0.490). The 95% prediction interval was 0.201-0.700, although its stability was limited. The largest descriptive estimates occurred for patellofemoral pain and central activation ratio (both r = 0.715), but both were based on the same two studies and four effect sizes, preventing separation of injury-type and index-class effects. Outcome-type differences were not significant (Q = 0.391, p = 0.823). Leave-one-out estimates remained positive (r = 0.419-0.531). Publication bias could not be assessed reliably.ConclusionEMG/neurophysiological indices may be positively associated with functional and function-related outcomes after lower-limb injury. However, the evidence base is small, subgroup findings are exploratory, and larger prospective studies using standardized protocols are needed.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"10538127261488143"},"PeriodicalIF":1.6,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Evren Sönmez, Lokman Ayhan, Salih Dere, Akın Öztürk, Suna Dilbaz, Abdurrahim Tekin, Engin Can, Selçuk Yapar, Serdar Çevik, Nuri Serdar Baş
{"title":"Acute trochanteric bursitis as an early complication of lumbosacral fusion: Incidence, risk factors, and therapeutic response.","authors":"Evren Sönmez, Lokman Ayhan, Salih Dere, Akın Öztürk, Suna Dilbaz, Abdurrahim Tekin, Engin Can, Selçuk Yapar, Serdar Çevik, Nuri Serdar Baş","doi":"10.1177/10538127261488167","DOIUrl":"https://doi.org/10.1177/10538127261488167","url":null,"abstract":"<p><p>BackgroundTrochanteric bursitis is an underrecognized cause of early postoperative lateral hip pain following lumbosacral fixation and may mimic radicular pain. Acute postoperative bursitis and its metabolic-mechanical determinants remain poorly characterized.MethodsA total of 310 patients who underwent lumbosacral fixation (2020-2024) were screened; 37 (11.9%) developed first-week lateral hip pain. After applying exclusion criteria, 30 magnetic resonance imaging (MRI)-confirmed acute trochanteric bursitis cases were age- and sex-matched 1:1 with 30 controls. Vitamin D, femoral neck T-scores, trochanteric Hounsfield units (HU), and a Composite Bone Quality Index (CBQI) were recorded. Outcomes were assessed using the Visual Analog Scale (VAS) and Harris Hip Score (HHS) at baseline, 3 months, and 12 months. Additive interaction analysis evaluated CBQI-BMI synergy. Receiver operating characteristic (ROC) analysis was used to determine the CBQI threshold.ResultsHigher BMI, lower vitamin D, reduced HU, and lower T-scores were associated with bursitis. CBQI demonstrated good discriminatory ability (area under the curve [AUC] 0.84; cut-off -0.50). Low CBQI combined with high BMI showed a supra-additive interaction. High-CBQI/low-BMI patients improved rapidly, whereas low-CBQI/high-BMI patients showed delayed recovery but achieved similar 12-month outcomes.ConclusionAcute postoperative trochanteric bursitis is influenced by both metabolic bone fragility and mechanical load. CBQI and BMI may help characterize high-risk phenotypes and early clinical trajectories. Preoperative assessment of vitamin D, HU-based bone density, and BMI may support risk stratification and targeted perioperative management.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"10538127261488167"},"PeriodicalIF":1.6,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148919868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Şafak Kuzu, Mehmet Canli, Irem Canli, Anıl Özüdoğru, Halil Alkan
{"title":"Integrating thoracic mobility into cervical rehabilitation improves mobility, function, and posture in non-specific chronic neck pain: A randomized controlled trial.","authors":"Şafak Kuzu, Mehmet Canli, Irem Canli, Anıl Özüdoğru, Halil Alkan","doi":"10.1177/10538127261488163","DOIUrl":"https://doi.org/10.1177/10538127261488163","url":null,"abstract":"<p><p>BackgroundChronic non-specific neck pain (CNNP) is a prevalent musculoskeletal disorder associated with pain, postural alterations, reduced spinal mobility, and functional limitations, and emerging evidence suggests that thoracic spine dysfunction may contribute to the persistence of symptoms.ObjectiveThis study investigated the effects of adding thoracic mobility exercises to cervical stabilization exercises on three distinct outcome domains in individuals with CNNP: cervical-specific parameters, including pain, cervical muscle strength, and neck disability; thoraco-spinal parameters, including posture and spinal mobility; and proximal upper extremity functionality.MethodsIn the study, 54 individuals with CNNP were randomized into thoracic mobility (TMG, n = 27) and cervical stabilization groups (CSG, n = 27). Cervical-specific parameters included pain intensity, cervical flexor and extensor strength, and neck-related disability. Thoraco-spinal parameters included posture and spinal mobility assessed using the Spinal Mouse<sup>®</sup> device. Proximal upper extremity functionality was assessed using the Disabilities of the Arm, Shoulder and Hand questionnaire. Outcomes were evaluated before treatment and immediately after completion at week six.ResultsWhile within-group improvements were observed for all parameters in both groups, adding thoracic mobility exercises provided no superior benefit for pain or cervical muscle strength compared with cervical stabilization alone. In contrast, significant Group × Time interactions favored the thoracic mobility group for posture (η<sup>2</sup> = 0.228), spinal mobility (η<sup>2</sup> = 0.306), neck disability (η<sup>2</sup> = 0.135), and upper extremity function (η<sup>2</sup> = 0.149).ConclusionThese findings support the targeted inclusion of thoracic mobility exercises for enhancing postural, spinal mobility, and functional outcomes in individuals with chronic non-specific neck pain, rather than achieving superior pain relief or cervical muscle strength improvement.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"10538127261488163"},"PeriodicalIF":1.6,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148919926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hazel Celik Guzel, Ozan Bahadır Turkmen, Ebru Kaya Mutlu
{"title":"Diminished vagal tone and altered muscle biomechanics in clinically based bruxism: An exploratory study of the autonomic-myogenic relationship.","authors":"Hazel Celik Guzel, Ozan Bahadır Turkmen, Ebru Kaya Mutlu","doi":"10.1177/10538127261487532","DOIUrl":"https://doi.org/10.1177/10538127261487532","url":null,"abstract":"<p><p>BackgroundBruxism is a complex condition with a multidimensional aetiology, wherein it is cross-sectionally associated with dysfunction of the autonomic nervous system (ANS); however, the relationships among ANS activity, muscle biomechanics, and pain remain unclear.ObjectiveThis study examined links among ANS activity, masticatory biomechanics, and pain in clinically based bruxism using quantitative methods.MethodsThis observational case-control study included 44 individuals with clinically based bruxism and 45 controls. Pain intensity (at rest and during chewing via Numeric Pain Scale), ANS activity (heart rate variability, heart rate, and respiratory rate via Polar H10), and masticatory muscle properties (tone, stiffness, and elasticity via MyotonPro) were measured.ResultsCompared to controls, the bruxism group showed impaired sympathovagal balance (LF/HF ratio: <i>p</i> < .001), reduced parasympathetic activity (HF power: <i>p</i> = .014), and altered muscle biomechanics (increased tone and stiffness, decreased elasticity; all <i>p</i> < .001). Correlation analyses found that lower HF power was negatively correlated with masseter stiffness (<i>r</i> = -.373, <i>p</i> = .043) and pain intensity (rest: <i>r</i> = -.387, <i>p</i> = .039; chewing: <i>r</i> = -.572, <i>p</i> = .018). Increased muscle tone and stiffness were positively correlated with pain intensity (<i>p</i> < .05).ConclusionThis exploratory study suggests a significant relationship among ANS dysfunction (specifically reduced parasympathetic activity), impaired muscle biomechanics, and pain in clinically based bruxism. These findings may provide a conceptual basis for multidisciplinary treatment strategies targeting ANS regulation in bruxism management.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"10538127261487532"},"PeriodicalIF":1.6,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148919874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amna Mohammed Ali Mustafa, Sitelbanat Osman Mohamed Ahmed, Salwa Ali Mousa, Maha Abdalla Abdlsadig Ali, Tahani Babiker Mohamed, Soad Mohamed Abdalla Alnassry, Asia Suliman Mohamed Ahmed, Fatma Abdalla Mohamed Abdalla, Mohammed Khalid Hussein Khalid
{"title":"School bag weight relative to body weight in primary school children: Nursing assessment and preventive implications in Khartoum state, Sudan.","authors":"Amna Mohammed Ali Mustafa, Sitelbanat Osman Mohamed Ahmed, Salwa Ali Mousa, Maha Abdalla Abdlsadig Ali, Tahani Babiker Mohamed, Soad Mohamed Abdalla Alnassry, Asia Suliman Mohamed Ahmed, Fatma Abdalla Mohamed Abdalla, Mohammed Khalid Hussein Khalid","doi":"10.1177/10538127261485414","DOIUrl":"https://doi.org/10.1177/10538127261485414","url":null,"abstract":"<p><p>BackgroundSchool bag load is a school-health concern, but weight percentage alone does not represent a complete ergonomic assessment. This study characterized school bag load relative to body weight and examined unadjusted associations with grade and anthropometric characteristics among primary school students in Khartoum State, Sudan.MethodsA descriptive cross-sectional study included 380 students aged 6-13 years from four randomly selected government schools between January and March 2025. Demographic data, body weight, height, BMI, and loaded school bag weight were recorded. A paired t-test, one-way ANOVA, Pearson correlation, and chi-square tests were used. Carrying method, trolley use, duration, distance, stairs, and musculoskeletal outcomes were not measured.ResultsMean school bag weight was 4.87 ± 1.88 kg and was significantly above the individualized 10%-of-body-weight reference value (<i>t</i> = 22.142, p < 0.001). Bag weight differed across grade, BMI, height, and weight categories (all <i>p</i> < 0.001) and correlated with height (<i>r</i> = 0.623), age (<i>r</i> = 0.587), body weight (<i>r</i> = 0.518), and BMI (<i>r</i> = 0.291). Overall, 62.1% of students carried bags weighing at least 10% of body weight.ConclusionA majority of participants exceeded the study-defined 10% relative-load reference. The associations with age, grade, height, and weight are descriptive and may reflect curricular progression and confounding among developmental variables. Because carriage conditions and clinical outcomes were not assessed, the findings characterize load exposure rather than ergonomic risk or musculoskeletal harm. Future studies should incorporate carriage duration and method, environmental demands, symptoms, posture, and multivariable analysis.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"10538127261485414"},"PeriodicalIF":1.6,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148906379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tolga Kaplan, Emel Güler, Musa Polat, Sümeyra Kaplan
{"title":"Clinical characteristics and functional determinants of central sensitization in chronic neck myofascial pain syndrome.","authors":"Tolga Kaplan, Emel Güler, Musa Polat, Sümeyra Kaplan","doi":"10.1177/10538127261485420","DOIUrl":"https://doi.org/10.1177/10538127261485420","url":null,"abstract":"<p><p>BackgroundCentral sensitization (CS) is a key mechanism in chronic pain, but its relationship with cervical muscle pressure pain thresholds (PPT) and disability in myofascial pain syndrome (MPS) remains unclear.ObjectiveTo investigate the clinical characteristics and functional determinants of CS in patients with chronic neck MPS.MethodsThis prospective cross-sectional study included 98 patients with chronic neck MPS. Participants were categorized into High CSI <math><mo>(</mo><mi>n</mi><mo>=</mo><mn>58</mn><mo>)</mo></math> and Low CSI <math><mo>(</mo><mi>n</mi><mo>=</mo><mn>40</mn><mo>)</mo></math> groups using a Central Sensitization Inventory (CSI) cutoff score of 40. Disability (NDI), neuropathic pain (painDETECT), quality of life (SF-12), and PPTs of the upper trapezius, levator scapulae (LSP), and splenius cervicis (SC) were assessed. Multivariate linear regression was performed.ResultsA high CSI score <math><mo>(</mo><mo>≥</mo><mn>40</mn><mo>)</mo></math>, reflecting prominent symptoms associated with central sensitivity, was identified in 59.2% of the participants. The High CSI group was significantly older and had higher BMI, NDI, and painDETECT scores (<i>p</i> < 0.05). Mean LSP PPT was significantly lower in the High CSI group (<i>p</i> = 0.003, rank-biserial correlation = 0.350), while splenius cervicis (SC) showed high sensitivity in both groups. The regression model explained 40% of the variance in CSI scores (R<sup>2</sup> = 0.40). NDI score (β = 0.48, <i>p</i> < 0.001) and age (β = 0.23, <i>p</i> = 0.01) were the only independent predictors.ConclusionsClinicians evaluating chronic neck MPS should routinely screen for CS using the CSI. Identifying a High CSI phenotype early enables the integration of multimodal, centrally-targeted therapies to mitigate severe functional disability, rather than relying solely on peripheral structural interventions.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"10538127261485420"},"PeriodicalIF":1.6,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148886916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Handol Jung, Shin Won Kwon, Hyung Jin Shin, Sunho Kim, Chanhee Shin, Taekyung Jin, Hohyun Jung, Youngoh Bae, Sung Hwan Hwang
{"title":"Long-term risk of degenerative spinal diseases following osteoporosis: A South Korean nationwide cohort study.","authors":"Handol Jung, Shin Won Kwon, Hyung Jin Shin, Sunho Kim, Chanhee Shin, Taekyung Jin, Hohyun Jung, Youngoh Bae, Sung Hwan Hwang","doi":"10.1177/10538127261485416","DOIUrl":"https://doi.org/10.1177/10538127261485416","url":null,"abstract":"<p><p>BackgroundOsteoporosis (OP) is a systemic skeletal disorder characterized by reduced bone density and microarchitectural deterioration, leading not only to fragility fractures but also to progressive spinal deformities. Recent evidence suggests that OP may contribute to degenerative spinal diseases (DSDs), yet longitudinal data remain limited.ObjectiveThis study aimed to evaluate the long-term risk and temporal relationship between newly diagnosed OP and subsequent development of major DSD subtypes using a nationwide population-based cohort.MethodsA retrospective cohort study was conducted by utilizing data from the Korean National Health Insurance Service (NHIS) between 2002 and 2013. Newly diagnosed OP cases were identified and matched 1:10 using propensity score matching. Outcomes included four major DSD subtypes-intervertebral disc disorders, spinal stenosis, spondylosis, and spondylolisthesis-identified using claims-based ICD-10 codes. Incidence rate ratios (IRRs) were calculated, and multivariable Cox proportional hazards models were applied to estimate adjusted hazard ratios (aHRs), controlling for demographic and clinical covariates. A 3-year washout period and up to 9 years of follow-up were implemented.ResultsAmong over one million participants, both osteoporosis groups-with and without pathological fractures-showed significantly elevated IRRs and aHRs for all major DSD subtypes compared with matched controls. The risk elevation was pronounced and sustained in OP patients without pathological fractures.ConclusionOP was independently associated with an increased long-term risk of DSDs, including among patients without pathological fractures. These findings underscore the need for early risk stratification and proactive spinal health management in patients with OP to mitigate the growing burden of spine disorders in aging populations.</p>","PeriodicalId":15129,"journal":{"name":"Journal of Back and Musculoskeletal Rehabilitation","volume":" ","pages":"10538127261485416"},"PeriodicalIF":1.6,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148880612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}