Journal of Basic Microbiology最新文献

{"title":"Issue Information: Journal of Basic Microbiology. 3/2026","authors":"","doi":"10.1002/jobm.70162","DOIUrl":"10.1002/jobm.70162","url":null,"abstract":"","PeriodicalId":15101,"journal":{"name":"Journal of Basic Microbiology","volume":"66 3","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jobm.70162","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147562321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Entomopathogenic Fungi as Orchestrators of Plant Defense, Growth, and Stress Tolerance—A Comprehensive Review","authors":"Yamini Rajendran,&nbsp;Shanmugam Pagalahalli Sankaran,&nbsp;Murugan Marimuthu,&nbsp;Tariq M. Butt,&nbsp;Geetha Nandagopal,&nbsp;Wanissa Mellikeche,&nbsp;Jeyarani Subramanian,&nbsp;Raghu Rajasekaran,&nbsp;Marimuthu Subramanian","doi":"10.1002/jobm.70161","DOIUrl":"10.1002/jobm.70161","url":null,"abstract":"<div>\u0000 \u0000 <p>Entomopathogenic fungi (EPF), including <i>Beauveria</i> spp., <i>Metarhizium</i> spp., <i>Lecanicillium</i> spp., and <i>Isaria</i> spp., help manage pest populations through direct infestation and insecticidal toxin production. Beyond pest control, they enhance plant growth and overall health, which makes them essential components of sustainable agriculture. EPF orchestrates systemic acquired resistance (SAR) and induced systemic resistance (ISR) via salicylic acid (SA) and jasmonic acid (JA) signalling pathways, respectively. Through these mechanisms, EPF promotes plant resilience against both biotic (pathogens and pests) and abiotic stresses (drought, nutrients, heat, and salinity), while improving nutrient uptake, hormone production, and soil quality. In addition, the secondary metabolites produced by EPF strengthen plant defense and stress tolerance. Their ability to persist as endophytes ensures long-term crop protection and growth stimulation. Incorporating EPF into Integrated pest management as a biocontrol agent reduces the reliance on chemical pesticides, enhances plant resistance, and supports environmental sustainability. This review examines the multifaceted contributions of EPF as a bioinoculant that promotes crop health and tolerance to biotic and abiotic stresses, and discusses the prospects for large-scale commercial applications.</p>\u0000 </div>","PeriodicalId":15101,"journal":{"name":"Journal of Basic Microbiology","volume":"66 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147306248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Precision Fermentation Processes for Producing Novel Foods and Its Sustainable Applications","authors":"Samuel Ayofemi Olalekan Adeyeye,&nbsp;A. Surendra Babu,&nbsp;Anukshya Subudhi,&nbsp;Blessing Rachael Adeyeye","doi":"10.1002/jobm.70160","DOIUrl":"10.1002/jobm.70160","url":null,"abstract":"<div>\u0000 \u0000 <p>Precision fermentation is rapidly transforming sustainable food production by enabling the controlled biosynthesis of ingredients that are resource-intensive or difficult to obtain through conventional agriculture. This review provides a system-level synthesis that integrates microbial strain design, bioprocess engineering, techno-economic feasibility, environmental performance, and regulatory readiness within a unified framework, addressing gaps left by prior product- or organism-focused reviews. Guided by PRISMA guidelines, literature published between 2010 and 2025 was systematically retrieved from Scopus, Web of Science, PubMed, and Google Scholar. A total of 154 records were identified, of which 42 duplicates were removed. Following title and abstract screening, 112 records were assessed for eligibility. After full-text evaluation, 37 studies—including laboratory investigations, industrial case studies, techno-economic analyses, and life-cycle assessments—met the inclusion criteria and were synthesized qualitatively. This review highlights major advances in precision fermentation, including improved microbial host selection, metabolic pathway engineering, and fermentation control for producing dairy-identical proteins, enzymes, flavors, and micronutrients. Life-cycle and techno-economic analyses show that strain choice, process design, and downstream processing strongly influence sustainability and commercial viability. Compared with conventional livestock and crop systems, precision fermentation typically requires less land and water, generates lower greenhouse gas emissions, and delivers consistent, contaminant-free products, supporting climate-resilient food systems. However, challenges remain, including high capital and energy costs, scale-up inefficiencies, downstream processing complexity, consumer acceptance, and regulatory uncertainty. Future progress depends on advances in synthetic biology, AI-driven optimization, renewable energy integration, and harmonized regulatory frameworks.</p>\u0000 </div>","PeriodicalId":15101,"journal":{"name":"Journal of Basic Microbiology","volume":"66 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147283839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to “Comparative Effects of Bacillus Strains Applied via Seed Biopriming and Soil Drenching Applications on the Morpho-Physiological and Transcriptional Aspects of Cotton”","authors":"","doi":"10.1002/jobm.70159","DOIUrl":"10.1002/jobm.70159","url":null,"abstract":"<p>Tahir Mahmood¹ | Anam Moosa¹ | Faisal Zulfiqar² | Muhammad Naveed Aslam¹ | Hongwei Zhao³ | Meisam Mohammadi⁴ | Tolga İzgü⁵ | Taner Bozkurt⁶ | Temoor Ahmed^7,8 | Doaa Bahaa Eldin Darwish⁹</p><p>Journal of Basic Microbiology, 2025; 65:e2400665</p><p>https://doi.org/10.1002/jobm.202400665</p><p><b>Affiliation 6</b>: ⁶Department of Plant Biotechnology, Korea Universtiy, South Korea</p><p><b>should be corrected to:</b></p><p>^<b>6</b><b>Toros Agri Industry and Trade Inc., R&amp;D Center, Adana, Turkey</b></p>","PeriodicalId":15101,"journal":{"name":"Journal of Basic Microbiology","volume":"66 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jobm.70159","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147283876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"GC–MS Profiling and In Silico Evaluation of Streptomyces levis Strain RS18 Against Phytopathogenic Fungi","authors":"Pavithra Velu,&nbsp;Lokesh Elumalai,&nbsp;Nithyalakshmi Mohanam,&nbsp;Sivarajan Anbalmani,&nbsp;Balagurunathan Ramasamy","doi":"10.1002/jobm.70157","DOIUrl":"10.1002/jobm.70157","url":null,"abstract":"<div>\u0000 \u0000 <p>The present study aimed to isolate and evaluate actinobacterial isolates for their antifungal potential against phytopathogenic fungi. A total of 20 morphologically distinct actinobacterial isolates were obtained from soil samples and screened against <i>Aspergillus niger, Aspergillus flavus, Aspergillus fumigatus</i>, and <i>Penicillium</i> sp. Among these, isolate RS18 exhibited the highest antifungal activity and was identified as <i>Streptomyces levis</i> based on 16S rRNA gene sequencing. Cultural characterization of this potent strain on various International Streptomyces Project media revealed distinct colony morphologies and pigment production patterns. Response Surface Methodology was employed to optimize the production conditions, and the ethyl acetate extract from the optimized culture demonstrated strong antifungal activity in both well diffusion and minimum fungicidal concentration assays. GC-MS analysis of the crude extract identified multiple bioactive compounds, including esters, alcohols, and nitrogen-containing heterocycles. ADMET analysis of the top compounds indicated high gastrointestinal absorption, non-mutagenicity, good drug-likeness, and predicted hepatotoxicity. Molecular docking studies revealed that 3,8-dimethyl-3-(4-methylpent-3-enyl)-11H-pyrano[3,2-a] carbazole had the highest binding affinity (–5.53 kcal/mol) with the Aspergillus hydrolase protein (1UKC), followed by other compounds with moderate binding energies. These results suggest that the strain <i>S. levis</i> RS18 is a promising biocontrol candidate against fungal phytopathogens and may be beneficial in agricultural practices to enhance crop production in target organisms.</p>\u0000 </div>","PeriodicalId":15101,"journal":{"name":"Journal of Basic Microbiology","volume":"66 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147275973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrated Experimental and Transcriptomic Analyses of Motility Genes in Ralstonia solanacearum F1C1","authors":"Sharmilee Sarkar,&nbsp;Mohit Yadav,&nbsp;Diganta Pegu,&nbsp;Aditya Kumar","doi":"10.1002/jobm.70158","DOIUrl":"10.1002/jobm.70158","url":null,"abstract":"<div>\u0000 \u0000 <p>The phytopathogen <i>Ralstonia solanacearum</i> is responsible for the “bacterial wilt disease” in several crop species worldwide, <i>viz</i>., tomato, brinjal, chilli, potato, groundnut, etc. This results in the yellowing of host plants, wilting, and finally their death. Motility is an essential requirement of plant pathogens, which helps them to infect and navigate through the host tissues and spread inside the host plant. The phytopathogen <i>R. solanacearum</i> exhibits motility such as twitching and swimming, which are governed by pili and flagella, respectively. This study aims to delineate the role of pili and flagella encoding genes, such as <i>pilY</i>_1, <i>fliP</i>, and <i>fliG</i>, by recognising the genes and their associated pathways. Disruption of these genes led to the creation of three motility mutants of the <i>R. solanacearum</i> F1C1 strain. Motility assays showed that the <i>ΔfliP</i> and <i>ΔfliG</i> mutants were significantly altered in terms of swimming ability. Further, transcriptomic analysis identified the differentially expressed genes in the respective altered mutants.</p></div>","PeriodicalId":15101,"journal":{"name":"Journal of Basic Microbiology","volume":"66 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146257585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Omics-Driven Insights Into Soil Microbial Diversity and Phytopathogen Interactions for Sustainable Agriculture and Food Security","authors":"Shumaila Parveen,&nbsp;Zaryab Shafi,&nbsp;Mohammad Shahid,&nbsp;Mohd Zobair Iqbal,&nbsp;Fahmi Naznine,&nbsp;Mohd Ikram Ansari","doi":"10.1002/jobm.70155","DOIUrl":"10.1002/jobm.70155","url":null,"abstract":"<div>\u0000 \u0000 <p>Soil microbial diversity plays a pivotal role in sustainable agriculture by regulating nutrient cycling, organic matter turnover, and natural suppression of phytopathogens, thereby supporting crop productivity and ecosystem resilience. However, intensive agricultural practices and environmental stressors have led to a decline in soil biodiversity, compromising soil functionality and food security. Recent advances in omics technologies—including metagenomics, transcriptomics, proteomics, and metabolomics offer powerful tools to unravel the complexity, of soil microbial communities and their interactions with plants and pathogens. These integrated approaches provide high-resolution insights into microbial structure, functional dynamics, metabolic pathways, and the mechanisms underpinning plant–microbe–pathogen interactions. Furthermore, omics-driven understanding supports the development of sustainable strategies such as organic farming, conservation practices, and microbial bioinoculants, which restore microbial diversity, enhance nutrient use efficiency, reduce chemical inputs, and mitigate disease pressure. By linking soil health to crop nutritional quality and broader food system sustainability, this review highlights the potential of omics-guided approaches to optimize soil microbial ecosystems for resilient agriculture and global food security.</p>\u0000 </div>","PeriodicalId":15101,"journal":{"name":"Journal of Basic Microbiology","volume":"66 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Biochar on Physiological and Biochemical Characteristics of Ganoderma lingzhi (Lingzhi) During Cultivation","authors":"Zhangjie Ning,&nbsp;Yinlan Jiang,&nbsp;Xiulian Duan,&nbsp;Ying Zhang,&nbsp;Bo Zhang,&nbsp;Shuang Hua,&nbsp;Xiao Li,&nbsp;Jinghan Wu","doi":"10.1002/jobm.70152","DOIUrl":"10.1002/jobm.70152","url":null,"abstract":"<div>\u0000 \u0000 <p>This study focused on <i>Ganoderma</i> mycelium as the experimental subject and conducted a systematic investigation into the effects of varying the addition ratio of biomass charcoal in the cultivation substrate. The objective was to thoroughly evaluate how differences in biochar proportions influence the growth and developmental characteristics of <i>Ganoderma</i> mycelium. Throughout the experimental process, several critical growth and physiological parameters were monitored and analyzed, including the mycelial growth rate, water retention capacity of the substrate, extracellular enzyme activity (TP, POD, SOD, CAT), as well as the levels of soluble sugar and protein within the mycelium. After a series of experiments, the results showed that biochar addition significantly enhanced mycelial growth rate (<i>p</i> &lt; 0.05) and extracellular enzyme activities while decreasing protein levels. Furthermore, the group with 20 g of biochar addition significantly enhanced the extracellular enzyme activity (<i>p</i> &lt; 0.05), thereby improving the ability of the mycelium to decompose and utilize the nutrients in the substrate. In conclusion, appropriately adjusting the addition of biochar has a significant impact on regulating the growth and physiological metabolism of the Ganoderma lucidum mycelium. These research results provide a scientific basis for optimizing cultivation techniques to increase the yield and quality of <i>Ganoderma lingzhi</i>.</p></div>","PeriodicalId":15101,"journal":{"name":"Journal of Basic Microbiology","volume":"66 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced Monacolin K Production in Monascus purpureus Via Mutagenesis and Nitrogen Source Optimization","authors":"Chen Yang,&nbsp;Yang Yajing,&nbsp;Hong Housheng","doi":"10.1002/jobm.70151","DOIUrl":"10.1002/jobm.70151","url":null,"abstract":"<p><i>Monascus</i> fungi are valued for their production of Monacolin K (MK), a bioactive compound with recognized lipid-lowering and multifunctional properties. To enhance MK yield in solid-state fermentation, this study combined atmospheric and room-temperature plasma (ARTP) mutagenesis with L-arginine supplementation. A mutant strain, C-23, was obtained, and the addition of L-arginine increased MK production by 97.3%, reaching 9.45 mg/g. Untargeted metabolomics revealed that L-arginine reshaped metabolic pathways related to amino acids, cofactors, carbohydrates, and lipids, elucidating the mechanism behind MK overproduction. This work provides a strategic approach for developing high-yielding <i>Monascus</i> strains and offers insights into the metabolic regulation of MK biosynthesis.</p>","PeriodicalId":15101,"journal":{"name":"Journal of Basic Microbiology","volume":"66 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12895299/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146165268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harnessing Genetic Engineering for Petrochemical Waste Detoxification: Mechanisms and Recent Breakthroughs","authors":"Atul Kumar Srivastava,&nbsp;Gyanendra Tripathi,&nbsp;Vikram Singh,&nbsp; Ashish,&nbsp;Xin Xie","doi":"10.1002/jobm.70140","DOIUrl":"10.1002/jobm.70140","url":null,"abstract":"<div>\u0000 \u0000 <p>Petrochemicals have emerged as an environmental hazard requiring innovative, sustainable remediation strategies. Bioremediation, specifically by genetically modified microorganisms (GMMs), is well known to produce surfactants that have emerged as a promising source to catalyze the efficiency of hydrocarbon degradation. The surfactant produced by GMMs facilitates the emulsification and dispersion of petroleum hydrocarbons. This review discusses the current state of biodegradation research, specifically on GMMs engineered to synthesize surfactant, which play an important role in enhancing the solubility of hydrophobic contaminants, such as oil components, thereby enhancing microbial access for degradation. The GMMs explored to optimize surfactant production and tailor their bioremediation efficiency. Furthermore, highlights the environmental benefits of utilizing GMMs for surfactant production, emphasizing the potential for a sustainable and cost-effective remediation strategy. Challenges and ethical considerations associated with the release of genetically modified organisms into the environment are also discussed, underscoring the importance of thorough risk assessments and regulatory frameworks. In conclusion, the integration of GMMs capable of producing surfactants presents a promising avenue for addressing petrochemicals through efficient and environmentally conscious bioremediation strategies. Future research should focus on optimizing the performance and safety of these engineered organisms to ensure their successful application in real-world environmental scenarios.</p>\u0000 </div>","PeriodicalId":15101,"journal":{"name":"Journal of Basic Microbiology","volume":"66 2","pages":""},"PeriodicalIF":2.7,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146113151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}