Journal of Basic Microbiology最新文献_第3页

A Review on Rare and Symbiotic Actinobacteria: Emerging Biotechnological Tools Against Antimicrobial Resistance. 稀有和共生放线菌：抗抗生素耐药性的新兴生物技术工具。

IF 3.5 4区生物学

Journal of Basic Microbiology Pub Date : 2025-04-16 DOI: 10.1002/jobm.70036

Ariel Mesquita, Davi Cerqueira, Matheus Rocha, Dino Silva, Claudia Martins, Bartolomeu Souza

{"title":"A Review on Rare and Symbiotic Actinobacteria: Emerging Biotechnological Tools Against Antimicrobial Resistance.","authors":"Ariel Mesquita, Davi Cerqueira, Matheus Rocha, Dino Silva, Claudia Martins, Bartolomeu Souza","doi":"10.1002/jobm.70036","DOIUrl":"https://doi.org/10.1002/jobm.70036","url":null,"abstract":"Antimicrobial resistance (AMR) poses a global threat to public health, with projections estimating 10 million deaths annually by 2050 if current trends persist. Actinobacteria, renowned for their biosynthetic capacity, are a key source of bioactive compounds, producing over 75% of known antibiotics. The adaptability of these microorganisms allows them to thrive in diverse habitats, including extreme ones, through the production of secondary metabolites that are of paramount importance for industry. Furthermore, actinobacteria are capable of living in symbiosis with several organisms, producing metabolites to protect and promote the growth of the host in exchange for nutrients and shelter. Some of these metabolites, such as antibiotics, play a key role in combating host pathogens and can be biotechnologically exploited to combat human resistant pathogens. This review presents the origins of AMR, the unique biology of actinobacteria, as well as their diverse biosynthetic pathways and their role in mitigating the AMR crisis. It also highlights the need for innovative biotechnological strategies for the isolation of rare and understudied actinobacteria, as symbiotic actinobacteria, to avoid rediscovery of molecules while finding new potential natural products and scaffolds for synthetic drugs. By providing a better understanding of their ecological, genomic, and metabolic diversity, this review provides valuable insights into the exploration of rare and symbiotic actinobacteria for developing antimicrobial solutions.","PeriodicalId":15101,"journal":{"name":"Journal of Basic Microbiology","volume":" ","pages":"e70036"},"PeriodicalIF":3.5,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nonanol, an Induced Biomolecule Produced by Bacillus atrophaeus NMB01 During Interaction With Phytophthora infestans Can be Explored as a Novel Formulation for the Management of Late Blight of Potatoes. 萎缩芽孢杆菌NMB01在与疫霉相互作用过程中产生的诱导生物分子Nonanol可作为马铃薯晚疫病防治的新制剂。

IF 3.5 4区生物学

Journal of Basic Microbiology Pub Date : 2025-04-15 DOI: 10.1002/jobm.70033

Janani Ragunathan, Krishna Nayana R U, Suhail Ashraf, Sevugapperumal Nakkeeran, Saranya Nallusamy, Kadiri Mahendra, Mohammad Raish

{"title":"Nonanol, an Induced Biomolecule Produced by Bacillus atrophaeus NMB01 During Interaction With Phytophthora infestans Can be Explored as a Novel Formulation for the Management of Late Blight of Potatoes.","authors":"Janani Ragunathan, Krishna Nayana R U, Suhail Ashraf, Sevugapperumal Nakkeeran, Saranya Nallusamy, Kadiri Mahendra, Mohammad Raish","doi":"10.1002/jobm.70033","DOIUrl":"https://doi.org/10.1002/jobm.70033","url":null,"abstract":"Phytophthora infestans, the pathogen responsible for late blight, continues to pose a significant risk to worldwide potato cultivation, including its historical impact during the Irish Potato Famine. Traditional management relies heavily on synthetic fungicides, but their prolonged use has led to fungicide resistance and environmental concerns. This study examines the potential of the bacterial endophyte Bacillus atrophaeus NMB01 as a biocontrol agent against P. infestans. Six biomolecules produced by B. atrophaeus NMB01 were docked against 15 P. infestans protein targets, with 1-nonanol, glafenine hydrochloride, and mucic acid showing high binding affinity. Wet lab assays confirmed that 1-nonanol inhibited P. infestans mycelial growth by 78% at 2 ppm. Molecular dynamics simulations validated the stability of these interactions. A tri-trophic interaction study identified additional volatile and non-volatile organic compounds (VOCs/NVOCs), with minocycline and doxazosin exhibiting strong binding across all targets. Transcriptome analysis of P. infestans exposed to 1-nonanol revealed differential gene expression, with upregulated genes linked to stress responses and downregulated genes, such as TAR1, cysteine synthase, and glutathione transferase, presenting novel antifungal targets. This study highlights 1-nonanol as a promising eco-friendly alternative to conventional fungicides, offering a sustainable solution for managing late blight and advancing potato cultivation resilience.","PeriodicalId":15101,"journal":{"name":"Journal of Basic Microbiology","volume":" ","pages":"e70033"},"PeriodicalIF":3.5,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144006766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genotypic, Biological and Chemical Control of Fusarium Isolated From Different Crops With Zearalenone Toxin Detection. 玉米赤霉烯酮毒素检测不同作物镰刀菌的基因型及生物化学防治。

IF 3.5 4区生物学

Journal of Basic Microbiology Pub Date : 2025-04-13 DOI: 10.1002/jobm.70027

Mohamed A Hussein, Youssuf A Gherbawy, Eman G A M El-Dawy

{"title":"Genotypic, Biological and Chemical Control of Fusarium Isolated From Different Crops With Zearalenone Toxin Detection.","authors":"Mohamed A Hussein, Youssuf A Gherbawy, Eman G A M El-Dawy","doi":"10.1002/jobm.70027","DOIUrl":"https://doi.org/10.1002/jobm.70027","url":null,"abstract":"Cereals and other crops are often heavily laden with Fusarium species and are mostly contaminated with mycotoxins that have a serious effect on public health. Twenty-six strains of Fusarium were collected from different crops in the Qena Governorate. According to phylogenetic analysis of Translation Elongation Factor 1 alpha sequences, the collected strains were identified as F. andiyazi, F. chlamydosporum, F. equiseti, F. incarnatum, F. proliferatum, F. thapsinum and F. verticillioides. Using VICAM fluorometers, 100% of the tested strains were zearalenone (ZEN) producers on rice medium after 4 weeks of incubation at 25°C. The amounts of ZEN ranged from 0.025 to 0.69 ppm, with highest amounts were detected in F. equiseti AEMCF19, followed by F. chlamydosporum AEMCF17 come from barely. Also, the control of Fusarium growth was studied by biological and chemical methods. Fusarium growth was greatly depressed by Macrophomina phaseolina and the maximum suppression (73.7%) was detected against F. verticillioides AEMCF1 which was isolated from maize. The efficacy of zinc sulfate against the growth and conidia production of Fusarium was concentration-dependent. The growth of 34.6% of strains was completely stopped at 10 mM of ZnSO4. The conidia production in 23% of strains was promoted by a low dose (1 or 5 mM) of ZnSO4 and potentially repressed or stopped at the higher dose.","PeriodicalId":15101,"journal":{"name":"Journal of Basic Microbiology","volume":" ","pages":"e70027"},"PeriodicalIF":3.5,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Issue Information: Journal of Basic Microbiology. 4/2025 期刊信息：Journal of Basic Microbiology. 4/2025

IF 3.5 4区生物学

Journal of Basic Microbiology Pub Date : 2025-04-07 DOI: 10.1002/jobm.70031

引用次数: 0

Cover: Journal of Basic Microbiology. 4/2025 封面：Journal of Basic Microbiology. 4/2025

IF 3.5 4区生物学

Journal of Basic Microbiology Pub Date : 2025-04-07 DOI: 10.1002/jobm.70032

引用次数: 0

Evaluating the Phytohormone Proficiencies of Multifarious Bacillus rugosus for Growth Promotion in Arachis hypogaea (L.). 评价不同芽孢杆菌对花生生长促进作用的植物激素水平。

IF 3.5 4区生物学

Journal of Basic Microbiology Pub Date : 2025-04-03 DOI: 10.1002/jobm.70011

Aniruddh Rabari, Janki Ruparelia, Chaitanya Kumar Jha, Kahkashan Perveen, Abhijit Debnath, Maheshwari Behra, Andrea Mastinu

{"title":"Evaluating the Phytohormone Proficiencies of Multifarious Bacillus rugosus for Growth Promotion in Arachis hypogaea (L.).","authors":"Aniruddh Rabari, Janki Ruparelia, Chaitanya Kumar Jha, Kahkashan Perveen, Abhijit Debnath, Maheshwari Behra, Andrea Mastinu","doi":"10.1002/jobm.70011","DOIUrl":"https://doi.org/10.1002/jobm.70011","url":null,"abstract":"The application of Plant Growth-Promoting Rhizobacteria (PGPR) in agriculture is increasingly emphasized as a sustainable alternative to hazardous agrochemicals. This study aimed to isolate and characterize PGPR strains from the rhizospheric soil of Arachis hypogaea L., hypothesizing that the rhizosphere of a healthy plant harbors beneficial microbes with significant plant growth-promoting (PGP) attributes. The isolate AB1 demonstrated promising PGP traits, including phosphate solubilization (56.44 µg mL⁻¹), zinc solubilization (6.1 µg mL⁻¹), ammonia production (3.8 µM µg mL⁻¹), and the synthesis of hydrogen cyanide (HCN) and phytohormones. Objectives included identifying these traits and evaluating their impact on the growth of Arachis hypogaea L. Phytohormonal profiling of AB1 through Gas Chromatography-Mass Spectrometry (GC-MS) and Fourier Transform Infrared Spectroscopy (FTIR) confirmed indole fractions with characteristic peaks at 3338 cm⁻¹ (N-H stretching), 1641 cm⁻¹ (C-N bond of the indole ring), and 2984 cm⁻¹ (C-H aromatic stretching). Cytokinins and gibberellins were also detected. Molecular, physiological, and biochemical analyses identified the isolate as Bacillus rugosus AB1, with gene sequences deposited under GenBank accession number MZ373174. The present study is the first report of Bacillus rugosus AB1 as a PGPR, showcasing multifaceted PGP traits that significantly enhanced root and shoot growth, biomass, and chlorophyll content in Arachis hypogaea L., demonstrating its potential as a biofertilizer for sustainable agriculture.","PeriodicalId":15101,"journal":{"name":"Journal of Basic Microbiology","volume":" ","pages":"e70011"},"PeriodicalIF":3.5,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Actinobacteria as Proficient Biocontrol Agents for Combating Fungal Diseases in Forest Plant Species. 放线菌是森林植物真菌病的有效生物防治剂。

IF 3.5 4区生物学

Journal of Basic Microbiology Pub Date : 2025-04-02 DOI: 10.1002/jobm.70030

Pooja Kapoor, Pooja Joshi, Manoj Pal, Vipin Parkash

{"title":"Actinobacteria as Proficient Biocontrol Agents for Combating Fungal Diseases in Forest Plant Species.","authors":"Pooja Kapoor, Pooja Joshi, Manoj Pal, Vipin Parkash","doi":"10.1002/jobm.70030","DOIUrl":"https://doi.org/10.1002/jobm.70030","url":null,"abstract":"Treating fungal pathogens with biocontrol agents and their bio-products is a cost effective, environmental friendly and suitable alternative strategy for managing fungal phytopathogens, minimizing the need for synthetic chemical fungicides. Actinomycetota/Actinobacteria are globally accepted as a major contributor and potent biological control agents in controlling fungal plant diseases. The objective of this review is to evaluate the promising biocontrol efficacy of Actinomycetota in managing fungal pathogens causing diseases in forest plant species, an area that has received less attention compared to crops. It aims to highlight the importance of Actinomycetota, mechanisms of the biocontrol process against phytopathogens, the commercial applications of Streptomyces spp. as effective biocontrol agents and research trends, emphasizing their role as an environmentally sustainable alternative to synthetic fungicides. Additionally, the study identifies possibilities and provides recommendations for future research on Actinomycetota's potential as proficient biocontrol agents against fungal pathogens in forestry.","PeriodicalId":15101,"journal":{"name":"Journal of Basic Microbiology","volume":" ","pages":"e70030"},"PeriodicalIF":3.5,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pseudomonas From Extreme Environments: Physiological and Molecular Adaptations. 极端环境中的假单胞菌：生理和分子适应。

IF 3.5 4区生物学

Journal of Basic Microbiology Pub Date : 2025-03-28 DOI: 10.1002/jobm.70028

Leandro Pio de Sousa

引用次数: 0

Enhancing Pea Plant Growth, Nutrient Acquisition, and Symbiosis in Cobalt-Stressed Soil Using Metal-Tolerant Klebsiella sp. 利用耐金属克雷伯氏菌促进钴胁迫土壤中豌豆植株生长、养分获取和共生

IF 3.5 4区生物学

Journal of Basic Microbiology Pub Date : 2025-03-28 DOI: 10.1002/jobm.70025

Mohammad Danish, Mohammad Shahid, Sobhy M Ibrahim, Lukman Ahamad

{"title":"Enhancing Pea Plant Growth, Nutrient Acquisition, and Symbiosis in Cobalt-Stressed Soil Using Metal-Tolerant Klebsiella sp.","authors":"Mohammad Danish, Mohammad Shahid, Sobhy M Ibrahim, Lukman Ahamad","doi":"10.1002/jobm.70025","DOIUrl":"https://doi.org/10.1002/jobm.70025","url":null,"abstract":"Excessive cobalt (Co) levels in agricultural soil cause significant toxicity, reducing crop growth and yield. This study aimed to assess the potential of Klebsiella sp. SRB-5 (Accession no. OR715782), in mitigating cobalt toxicity and enhancing the growth of garden peas under cobalt stress. Strain SRB-5, tolerant to 4000 ppm of Co(II), was evaluated for producing growth-regulating substances, including indole-3-acetic acid (IAA), ammonia, siderophore, ACC deaminase, and solubilized phosphate, under cobalt stress. The optimal conditions for Co-(II) biosorption by SRB-5 were determined to be 25°C, pH 6.0, and an incubation time of 72 h. The strain's ability to mitigate Co-(II) toxicity was tested by inoculating peas grown in soil treated with 1000, 2000, and 3000 ppm Co-(II). Inoculation with Co-tolerant SRB-5 alleviated cobalt toxicity and significantly enhanced the physiological and biochemical properties of plants. Notably, SRB-5 increased root length (19.2%), root biomass (29%), seedling vigor index (18.4%), total chlorophyll (52%), nodule biomass (41%), leghaemoglobin content (38%), root nitrogen (27%), and phosphorous content (19.3%) in 1000 ppm Co-stressed peas. Additionally, bacterial inoculation reduced proline, malondialdehyde (MDA), hydrogen peroxide (H2O2), and membrane injury by 85%, 57.3%, 90%, and 75%, respectively, in 1000 ppm Co-exposed plants. Priming with SRB-5 also reduced cobalt uptake in roots (88%), shoots (53.7%), and grains (79.6%) compared to uninoculated treatments. Metal-tolerant beneficial soil bacteria, such as Klebsiella sp. strain SRB-5, could serve as an effective alternative for enhancing pea production in metal-contaminated soils. The use of Co-tolerant PGPR strains holds potential for development as biofertilizers in future agricultural practices.","PeriodicalId":15101,"journal":{"name":"Journal of Basic Microbiology","volume":" ","pages":"e70025"},"PeriodicalIF":3.5,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Special Issue: Gene Expression and Regulation 特刊：基因表达与调控。

IF 3.5 4区生物学

Journal of Basic Microbiology Pub Date : 2025-03-28 DOI: 10.1002/jobm.70029

Erika Kothe

引用次数: 0