Journal of Asthma最新文献

筛选
英文 中文
Lingganwuweijiangxin Decoction suppresses allergic airway inflammation in Guinea pigs with cough variant asthma by regulating the treg/Th17 balance and the JAK1/STAT6 signaling pathway. 灵肝五味降心汤通过调节treg/Th17平衡和JAK1/STAT6信号通路抑制豚鼠咳嗽变异性哮喘变应性气道炎症。
IF 1.7 4区 医学
Journal of Asthma Pub Date : 2025-08-01 Epub Date: 2025-03-06 DOI: 10.1080/02770903.2025.2472357
Yu Lai, Fengyi He, Jingyi Tang, Xuannan Chen, Shiqing Yuan, Qi Zhang
{"title":"Lingganwuweijiangxin Decoction suppresses allergic airway inflammation in Guinea pigs with cough variant asthma by regulating the treg/Th17 balance and the JAK1/STAT6 signaling pathway.","authors":"Yu Lai, Fengyi He, Jingyi Tang, Xuannan Chen, Shiqing Yuan, Qi Zhang","doi":"10.1080/02770903.2025.2472357","DOIUrl":"10.1080/02770903.2025.2472357","url":null,"abstract":"<p><strong>Background: </strong>Lingganwuweijiangxin Decoction (LD) is an effective prescription widely used to treat cough variant asthma (CVA) in traditional Chinese medicine, although its mechanisms remain unclear. This study investigates the therapeutic effects and underlying mechanisms of LD on CVA.</p><p><strong>Methods: </strong>A guinea pig CVA model was treated with either LD or budesonide (BUD). Capsaicin aerosol-induced coughs were recorded. Pathological changes were then examined using hematoxylin and eosin staining, transmission electron microscopy, and Wright-Giemsa staining of bronchoalveolar lavage fluid (BALF). Inflammatory cytokines were measured by enzyme-linked immunosorbent assay. mRNA expression levels of transcription factors forkhead box P3 (Foxp3), retinoic acid-related orphan receptor γt (RORγt), Janus kinase 1 (JAK1), signal transducer and activator of transcription 6 (STAT6), the transient receptor potential ankyrin 1 (TRPA1), and transient receptor potential vanilloid 1 (TRPV1) in lung tissue were detected by real-time reverse transcription polymerase chain reaction, and protein levels of these markers were assessed by Western blotting.</p><p><strong>Results: </strong>Compared to the control group, the model group showed significantly more coughs, which were markedly reduced by LD treatment (<i>p</i> = 0.0083 and <i>p</i> = 0.0117). LD treatment also decreased inflammatory cell infiltration, alveolar epithelial hyperplasia, and mitochondrial swelling in ciliated cells, consistent with the lung tissue injury score (<i>p</i> < 0.0001). LD significantly reduced the ovalbumin-induced elevation of TRPA1 (<i>p</i> < 0.01 and <i>p</i> < 0.0001), TRPV1 (<i>p</i> < 0.01 and <i>p</i> < 0.0001), and substance P (SP) levels (<i>p</i> < 0.05). Moreover, LD treatment increased <i>Foxp3</i> mRNA (<i>p</i> = 0.0013) and protein expression (<i>p</i> < 0.0001) and reduced <i>RORγt</i> mRNA (<i>p</i> < 0.0001). LD also decreased <i>JAK1</i> and <i>STAT6</i> transcription (<i>p</i> = 0.0021, <i>p</i> < 0.0001, respectively), with consistent effects observed at the protein level (<i>p</i> < 0.0001).</p><p><strong>Conclusions: </strong>LD significantly reduced coughs and airway inflammation in the CVA guinea pig model by regulating TRPA1, TRPV1, SP, regulatory T cell/T helper 17 cell balance, and the JAK1/STAT6 signaling pathway. These effects were comparable to BUD, suggesting that LD may be a viable alternative treatment for CVA.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1280-1295"},"PeriodicalIF":1.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global research trends and hotspots in mitochondria and asthma: a bibliometric and visualized analysis. 线粒体和哮喘的全球研究趋势和热点:文献计量学和可视化分析。
IF 1.7 4区 医学
Journal of Asthma Pub Date : 2025-08-01 Epub Date: 2025-03-17 DOI: 10.1080/02770903.2025.2478524
Leming Huang, Chuyan Wu, Feng Jiang, Xinxin Bu
{"title":"Global research trends and hotspots in mitochondria and asthma: a bibliometric and visualized analysis.","authors":"Leming Huang, Chuyan Wu, Feng Jiang, Xinxin Bu","doi":"10.1080/02770903.2025.2478524","DOIUrl":"10.1080/02770903.2025.2478524","url":null,"abstract":"<p><strong>Background: </strong>Asthma is a complex chronic respiratory disease marked by inflammation, bronchoconstriction, and hyperresponsiveness. Mitochondria, key regulators of energy production, ROS, and apoptosis, are increasingly recognized as crucial in asthma pathophysiology. However, a comprehensive analysis of global research trends in this area is lacking. This study aims to perform a bibliometric and visualized analysis of global research on mitochondria and asthma.</p><p><strong>Methods: </strong>A bibliometric analysis was conducted using Web of Science Core Collection data from 2004 to June 2024. CiteSpace and VOSviewer software were used to examine co-authorship, co-citation, keyword co-occurrence, and thematic clusters.</p><p><strong>Results: </strong>A total of 669 publications were identified. The number of studies grew significantly after 2015, with the United States, China, and the UK leading research. Co-citation and keyword analyses revealed mitochondrial dysfunction, oxidative stress, apoptosis, and airway inflammation as major themes. Emerging areas of interest include mitochondrial biogenesis, NLRP3 inflammasome, and innate immunity. Collaboration among institutions like Harvard University and the Council of Scientific & Industrial Research was significant, and journals, such as European Respiratory Journal and Nature Medicine were highly influential.</p><p><strong>Conclusion: </strong>This study provides an overview of research on mitochondria and asthma, highlighting emerging trends, such as mitochondrial biogenesis and immune pathways. Future research should focus on these areas and the role of environmental triggers in mitochondrial dysfunction, offering valuable insights for therapeutic strategies targeting mitochondria in asthma.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1371-1388"},"PeriodicalIF":1.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Attitudes, barriers, and facilitators for the use of rescue therapy in patients with mild to moderate asthma. 轻中度哮喘患者使用抢救治疗的态度、障碍和促进因素
IF 1.3 4区 医学
Journal of Asthma Pub Date : 2025-08-01 DOI: 10.1080/02770903.2025.2531490
Olga Milena García Morales, Carlos Andrés Celis-Preciado, Iván Solarte, Juliana Velosa-Porras
{"title":"Attitudes, barriers, and facilitators for the use of rescue therapy in patients with mild to moderate asthma.","authors":"Olga Milena García Morales, Carlos Andrés Celis-Preciado, Iván Solarte, Juliana Velosa-Porras","doi":"10.1080/02770903.2025.2531490","DOIUrl":"https://doi.org/10.1080/02770903.2025.2531490","url":null,"abstract":"<p><strong>Objective: </strong>To explore and understand the barriers and facilitators for correctly using maintenance/controller and rescue treatments in adults with mild to moderate asthma (GINA 2020 classification) attending a reference center for asthma in Bogotá, Colombia, during the years 2021-2022.</p><p><strong>Methods: </strong>A qualitative study with a phenomenological approach using semi-structured interviews with adults with mild to moderate asthma, under a purposive non-probabilistic sampling. Data analysis was conducted using Nvivo software (Version 11.0) through: reading and re-reading, memo generation, coding, category generation, and connection between categories.</p><p><strong>Results: </strong>Thirty-one patients were interviewed (mean age: 44.3 years) with a 1:1 male/female ratio. 77.4% with moderate asthma. Patients' experiences were grouped into three themes with 12 categories: barriers related to the individual (inadequate knowledge about maintenance inhalers, insufficient understanding of their current state due to lack of information, disagreement in treatment among non-adherent patients, and difficulties in implementation and practical application), barriers related to the healthcare system (lack of follow-up, medication availability, administrative procedures, and waiting times), and patient-related facilitators (adequate knowledge of the functioning and correct use of inhalers for treatment, proactive attitude, and motivation to receive information).</p><p><strong>Conclusion: </strong>Based on the identified barriers, educating patients about the pathophysiological mechanisms of asthma (inflammation and bronchodilation) and the concept of control adapted to the patient's language could facilitate the appropriate and adherent use of pharmacological therapy.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1-10"},"PeriodicalIF":1.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Update on the utilization of complementary therapies by adolescents with asthma in an urban population. 城市青少年哮喘患者补充治疗的最新进展
IF 1.7 4区 医学
Journal of Asthma Pub Date : 2025-08-01 Epub Date: 2025-03-08 DOI: 10.1080/02770903.2025.2475451
Gary K Soffer, Termeh Feinberg, Hillary Kroll, Marina Reznik
{"title":"Update on the utilization of complementary therapies by adolescents with asthma in an urban population.","authors":"Gary K Soffer, Termeh Feinberg, Hillary Kroll, Marina Reznik","doi":"10.1080/02770903.2025.2475451","DOIUrl":"10.1080/02770903.2025.2475451","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the prevalence and perceived efficacy of complementary and alternative medicine (CAM) use among urban adolescents with asthma, building on a previous landmark study, and to determine if CAM use varied by asthma severity, asthma control test (ACT), and non-CAM prescriptions for asthma treatment.</p><p><strong>Methods: </strong>An adapted survey was completed by 203 patients aged 13-18 years in outpatient specialty and primary care clinics in the Bronx, NY. Demographic information, adherence to prescription(s), ACT, and past year CAM utilization, perceived efficacy of CAM used, and substitution for prescription were assessed <i>via</i> self-report while severity, and related active prescriptions were derived through electronic health records. We conducted logistic regressions to determine if CAM use (yes/no) was associated with ACT (controlled/uncontrolled) or severity (persistent/intermittent).</p><p><strong>Results: </strong>82% of participants utilized at least one form of CAM in the management of their asthma. Mind-body (65%) and natural products (63%) were the most frequent with highest reported perceived efficacy (81%). Only 35% of patients discussed CAM use with their provider. ACT did not vary by CAM use (AOR: 1.57; 95%CI: 0.59, 4.15; <i>p</i> = 0.37), while prescription adherence was associated with a nearly seven-fold increase in CAM use (AOR: 7.79; 95%CI: 3.27, 18.54; <i>p</i><.0001).</p><p><strong>Conclusions: </strong>The prevalence of CAM use amongst Bronx adolescents with asthma has likely largely remained stable since an initial 2002 analysis. Despite a lack of association between CAM use and asthma control, there was a high degree of perceived efficacy. Adolescents who use CAM for asthma management may do so as an overall component of health-promoting behavior such as prescription adherence.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1304-1312"},"PeriodicalIF":1.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Severe asthma exacerbations associated with unconventional natural gas development activity in area of concentrated development. 在集中开发地区,非常规天然气开发活动与严重哮喘发作有关。
IF 1.7 4区 医学
Journal of Asthma Pub Date : 2025-08-01 Epub Date: 2025-04-01 DOI: 10.1080/02770903.2025.2483000
Jeanine M Buchanich, Ada O Youk, Jennifer Fedor, Michael Lann, Nicholas R Tedesco, Evelyn O Talbott, Maureen Lichtveld, James P Fabisiak, Sally Wenzel
{"title":"Severe asthma exacerbations associated with unconventional natural gas development activity in area of concentrated development.","authors":"Jeanine M Buchanich, Ada O Youk, Jennifer Fedor, Michael Lann, Nicholas R Tedesco, Evelyn O Talbott, Maureen Lichtveld, James P Fabisiak, Sally Wenzel","doi":"10.1080/02770903.2025.2483000","DOIUrl":"10.1080/02770903.2025.2483000","url":null,"abstract":"<p><strong>Introduction: </strong>Residential proximity to unconventional natural gas development (UNGD) has been shown to be associated with asthma exacerbations, but there is limited evidence regarding whether exacerbations are associated with a particular distance or phase of well activity.</p><p><strong>Objective: </strong>To study the impact of proximity to UNGD activity by well phase and buffer distance.</p><p><strong>Methods: </strong>We included asthma patients 5-90 years old with a primary diagnosis of asthma and at least one order for medications prescribed for asthma residing in one of eight Southwestern Pennsylvania counties between 2011 and 2020. We matched events (severe exacerbation, emergency department visit, hospitalization) by age group, sex, and year to cohort members without an event of the same or greater severity. The primary exposure measure was an inverse distance-weighted index of UNGD activity up to 10 miles of a patient's residence. We fit a series of adjusted multilevel logistic regression models using tertiles of exposure activity by well phase and buffer distance.</p><p><strong>Results: </strong>Our cohort consisted of 46,676 asthma patients. We found strong evidence for an increased risk specifically during the production phase for all buffer distances examined for all three event types, as based on consistent, statistically significantly elevated odds ratios. Elevations ranged from 2 to 8 times the baseline of no wells within 10 miles of the patient's residence.</p><p><strong>Conclusion: </strong>This study provides evidence of increased risk of asthma events with the production phase. This should be considered in determining risk communication and assessment for these vulnerable populations, particularly during the production phase.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1418-1430"},"PeriodicalIF":1.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shared decision-making in severe asthma therapy: qualitative study of physician-patient communication. 重症哮喘治疗中的共同决策:医患沟通的定性研究。
IF 1.7 4区 医学
Journal of Asthma Pub Date : 2025-08-01 Epub Date: 2025-06-18 DOI: 10.1080/02770903.2025.2488000
Ember Lu, Zachary Hebert, Katya Solovyeva, Lisa Kietzer, Zeina Eid Antoun, Rafael Alfonso-Cristancho
{"title":"Shared decision-making in severe asthma therapy: qualitative study of physician-patient communication.","authors":"Ember Lu, Zachary Hebert, Katya Solovyeva, Lisa Kietzer, Zeina Eid Antoun, Rafael Alfonso-Cristancho","doi":"10.1080/02770903.2025.2488000","DOIUrl":"10.1080/02770903.2025.2488000","url":null,"abstract":"<p><strong>Rationale: </strong>Biologics are indicated for severe asthma, but little is known about the factors driving patient and physician decisions surrounding their use.</p><p><strong>Objectives: </strong>To understand decision drivers for biologic use and conversational dynamics between patients with severe asthma and physicians.</p><p><strong>Methods: </strong>This retrospective database study used anonymized physician-patient conversations (recorded September 2018-August 2020) from routine clinical visits, captured in Verilogue's physician-patient syndicated database. Eligible conversations included those of patients with severe asthma, who were considering biologic therapy (Topic 1), had initiated biologic within 7 months of clinical visit (Topic 2), or were discontinuing/considering switching biologic treatment (Topic 3). Conversations were analyzed quantitatively and descriptively by topic.</p><p><strong>Results: </strong>Overall, 50 conversations between 14 physicians and 50 patients were included (considering biologic, <i>n</i> = 10; recent biologic initiation, <i>n</i> = 20; switched/discontinued biologic, <i>n</i> = 20). Physicians had 68-73% share of the conversation. When considering biologic treatment, the presence of symptoms (including coughing, wheezing, shortness of breath and chest tightness) drove the decision, with 3/10 patients providing additional symptom impact/severity details, and 2/10 describing adjustments to accommodate symptoms. Physicians set unspecified treatment goals and modest expectations for biologic efficacy, framing any symptom control as success (13/20 conversations). Patient symptom assessment drove the decision to continue, discontinue, or switch biologic treatment: in 5/20 cases, physicians asked patients if they were \"better\" or the medication is \"helping.\"</p><p><strong>Conclusions: </strong>This study suggests that patients relied on physicians to shape patient-physician interactions and treatment expectations. This suggests that shared decision-making may improve physicians' understanding of the impact severe asthma has on patients and facilitate the setting of treatment expectations.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1439-1449"},"PeriodicalIF":1.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heated high flow nasal cannula and bilevel positive airway pressure in pediatric asthma exacerbations. 加热高流量鼻插管和双水平气道正压治疗儿童哮喘加重。
IF 1.7 4区 医学
Journal of Asthma Pub Date : 2025-08-01 Epub Date: 2025-03-14 DOI: 10.1080/02770903.2025.2478122
Shelby Nelipovich, Lauren Ozdowski, Michele E Smith
{"title":"Heated high flow nasal cannula and bilevel positive airway pressure in pediatric asthma exacerbations.","authors":"Shelby Nelipovich, Lauren Ozdowski, Michele E Smith","doi":"10.1080/02770903.2025.2478122","DOIUrl":"10.1080/02770903.2025.2478122","url":null,"abstract":"<p><strong>Objective: </strong>Heated High Flow Nasal Cannula (HHFNC) and Bilevel Positive Airway Pressure (BPAP) are noninvasive respiratory support modalities used in pediatric asthma exacerbations. We aim to examine differences in characteristics and outcomes for patients admitted to the Pediatric Intensive Care Unit (PICU) on standard therapy (ST) alone (continuous albuterol and systemic corticosteroids), ST plus HHFNC, and ST plus BPAP.</p><p><strong>Methods: </strong>This is a retrospective and prospective observational cohort study. Chi-Squared/Fisher's exact and Kruskal Wallis tests were used for categorical and continuous outcomes, respectively.</p><p><strong>Results: </strong>129 patients were included. Younger patients were placed on HHFNC while more severe patients were placed on BPAP. A multiple linear regression controlling for age, sex, race, ethnicity, and exacerbation severity revealed that patients admitted on BPAP had a longer duration of continuous albuterol compared to patients on ST alone (<i>p</i> = 0.02). No differences were found in respiratory support escalation, duration of respiratory support, or adverse events. The BPAP group had the most sedation use and longest length of stay (LOS). Median hourly respiratory rates (RR) increased in the HHFNC group over the first 12 h of admission and remained stable or decreased in the ST and BPAP groups.</p><p><strong>Conclusions: </strong>This study found that BPAP use in pediatric asthma exacerbations is associated with increased exacerbation severity, longer duration of continuous albuterol, increased sedation use, and longer LOS. Although a multiple linear regression analysis was performed to control for multiple covariates including exacerbation severity, it is possible that intrinsic patient characteristics influenced these outcomes rather than BPAP usage.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1332-1340"},"PeriodicalIF":1.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial intelligence performance in pediatric asthma. 人工智能在儿童哮喘中的表现。
IF 1.3 4区 医学
Journal of Asthma Pub Date : 2025-08-01 DOI: 10.1080/02770903.2025.2531500
Ece Senbaykal Yigit, Ilke Taskirdi, Idil Akay Haci, Tuba Tuncel
{"title":"Artificial intelligence performance in pediatric asthma.","authors":"Ece Senbaykal Yigit, Ilke Taskirdi, Idil Akay Haci, Tuba Tuncel","doi":"10.1080/02770903.2025.2531500","DOIUrl":"10.1080/02770903.2025.2531500","url":null,"abstract":"<p><strong>Objective: </strong>Asthma is the most common chronic disease of childhood, characterized by symptoms such as wheezing, shortness of breath, and coughing. With the advancement of technology, artificial intelligence (AI) applications are increasingly being used in various fields, among which ChatGPT is one of the most widely utilized. The aim of this study is to evaluate the reliability, quality, and readability of the answers provided by the ChatGPT-4o application to questions related to pediatric asthma.</p><p><strong>Methods: </strong>The ChatGPT-4o application was used to record answers to 25 of the most frequently asked questions about asthma in children. To determine the quality and reliability of the answers, we used the Global Quality Scale and modified DISCERN tool. We tested readability using seven indices: Automated Readability Index, Flesch Reading Ease Score, Flesch-Kincaid Grade Level (FKGL), Gunning Fog Readability Index, Simple Measure of Gobbledygook, Coleman-Liau Readability Index, and Linsear Write Formula.</p><p><strong>Results: </strong>The answers provided by the ChatGPT-4o application to questions about childhood asthma were found to have good reliability (88% by the first evaluator and 84% by the second evaluator) and high quality (88% by both evaluators). The application scored 10.77 ± 1.58 on the FKGL scale, and in conjunction with the other indices, the results indicated that the answers required a high level of reading proficiency.</p><p><strong>Conclusions: </strong>Artificial intelligence can be a reliable tool for parents in providing information about pediatric asthma. However, these findings suggest that readability issues may hinder the clinical application of AI-generated content in asthma diagnosis and treatment.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1-7"},"PeriodicalIF":1.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144608450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Awareness of wildfire smoke among U.S. adults with and without asthma. 美国成年哮喘患者和非哮喘患者对野火烟雾的认识
IF 1.7 4区 医学
Journal of Asthma Pub Date : 2025-08-01 Epub Date: 2025-04-04 DOI: 10.1080/02770903.2025.2487994
Maria C Mirabelli, Tia C Dowling, Lauren Freelander, Audrey F Pennington, Scott A Damon
{"title":"Awareness of wildfire smoke among U.S. adults with and without asthma.","authors":"Maria C Mirabelli, Tia C Dowling, Lauren Freelander, Audrey F Pennington, Scott A Damon","doi":"10.1080/02770903.2025.2487994","DOIUrl":"10.1080/02770903.2025.2487994","url":null,"abstract":"<p><strong>Objective: </strong>To describe awareness of ambient wildfire smoke among U.S. adults with and without asthma.</p><p><strong>Methods: </strong>We analyzed data from the summer wave of the 2021 <i>ConsumerStyles</i> survey, a nationally representative survey of 4085 U.S. adults. Respondents self-reported their asthma status and awareness of wildfire smoke where they lived in the past 12 months. We linked survey responses by zip code of residence with satellite-detected wildfire smoke plume data that estimated the daily maximum smoke plume density over the preceding year. We estimated associations between asthma status and awareness of wildfire smoke across categories of maximum smoke plume density and days with medium- or heavy-density smoke as prevalence ratios (PRs) with 95% confidence intervals (CIs) using predicted marginal probabilities from logistic regression models.</p><p><strong>Results: </strong>Over 98% of the estimated population of U.S. adults lived in a zip code affected by ≥1 day of medium- or heavy-density wildfire smoke, which occurred on an average of 16 days in the past year. Awareness of wildfire smoke was reported by 19% of U.S. adults and was higher among adults with than without asthma (PR: 1.25; 95% CI: 1.01, 1.55), including in zip codes affected by heavy-density smoke (PR: 1.30, 95% CI: 1.04, 1.63) and with 22 or more days of medium- to heavy-density smoke (PR: 1.22, 95% CI: 1.01, 1.47).</p><p><strong>Conclusions: </strong>Although awareness of wildfire smoke was higher among U.S. adults with than without asthma, low percentages of awareness overall indicate a need for health communication about wildfire smoke and its health risks.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1431-1438"},"PeriodicalIF":1.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12286720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding how sleep disorders are managed in people with asthma: a scoping review of the literature. 了解哮喘患者如何管理睡眠障碍:文献综述。
IF 1.7 4区 医学
Journal of Asthma Pub Date : 2025-08-01 Epub Date: 2025-05-04 DOI: 10.1080/02770903.2025.2487986
Emma Yau, Janet M Y Cheung, Bandana Saini, Stephen Hughes
{"title":"Understanding how sleep disorders are managed in people with asthma: a scoping review of the literature.","authors":"Emma Yau, Janet M Y Cheung, Bandana Saini, Stephen Hughes","doi":"10.1080/02770903.2025.2487986","DOIUrl":"10.1080/02770903.2025.2487986","url":null,"abstract":"<p><strong>Objective: </strong>People with asthma may experience sleep disturbances due to uncontrolled asthma symptoms and/or co-occurring sleep disorders. Asthma shares pathophysiological pathways with sleep disorders including insomnia and obstructive sleep apnea and the interrelationship between asthma and sleep disorders is bi-directional. Insufficient sleep in general and in people with asthma leads to worsened mental and physical health. How this is managed in people with asthma is less known.</p><p><strong>Data sources: </strong>This scoping review examines current literature around sleep health management employed by people with asthma and their care providers. Peer reviewed journal articles on sleep health interventions/management in adults with comorbid asthma were searched for in 4 databases, across 10 years, in a search strategy developed with medical librarians.</p><p><strong>Study selection: </strong>The search led to the inclusion of 13 studies that met the review criteria, which reported sleep management interventions tested in people with sleep disorders comorbid with asthma.</p><p><strong>Results: </strong>For people with obstructive sleep apnea and asthma, continuous positive pressure devices, oral appliances and bariatric surgery improved sleep and asthma outcomes. Improvements in other sleep disorders and asthma were shown with behavioral interventions and digital interventions including fitness tracker use.</p><p><strong>Conclusion: </strong>The limited studies retrievable on this topic suggest management of sleep disorders in people with asthma is an under-researched area. Future research directed at how and when to assess sleep management in people with asthma will better inform specific guidelines and achieve improved sleep health in this population.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1266-1279"},"PeriodicalIF":1.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信