Journal of Asthma最新文献

{"title":"The impact of biologic therapy on work capacity and workforce attachment in patients with severe asthma.","authors":"Kjell Erik Julius Håkansson, Rikke Ibsen, Niels Steen Krogh, Marianne Baastrup Soendergaard, Susanne Hansen, Anne-Sofie Bjerrum, Anna von Bülow, Ole Hilberg, Anders Løkke, Barbara Bonnesen, Claus Rikard Johnsen, Sofie Lock-Johansson, Lycely Dongo, Maria Bisgaard Borup, Roxana Vijdea, Linda Makowska Rasmussen, Johannes Martin Schmid, Charlotte Suppli Ulrik, Celeste Porsbjerg","doi":"10.1080/02770903.2025.2472356","DOIUrl":"10.1080/02770903.2025.2472356","url":null,"abstract":"<p><strong>Introduction: </strong>Severe asthma impacts work capacity, but little is known about the effects of biologic therapy on patients' ability to work. We aimed to assess the impact of biologic therapy for severe asthma on work capacity and workforce attachment.</p><p><strong>Methods: </strong>This cohort study used the Danish Severe Asthma Register, comprising all Danish patients with severe asthma initiating biologic therapy. Earned income, hours worked, and workforce attachment were tracked in national databases from one year prior to biologic therapy as well as during 2 years of biologic therapy. Outcomes were compared to age-, sex-, cohabitation- and residence-matched controls from the general population.</p><p><strong>Results: </strong>Overall, 381 patients aged 20-62 years (52% females) were included. Annual weeks worked were lower among patients with severe asthma (adjusted incidence rate ratio (aIRR) 0.82 (0.80-0.84)), driven by increases in sick leave (aIRR 2.77 (2.58-2.98)), unemployment (aIRR 1.38 (1.30-1.46)) and disability pension (aIRR 1.85 (1.76-1.94)). After initiating biologic therapy, patients saw modest increases in annual hours worked during the second year of treatment (aIRR 1.03 (1.03-1.04)). However, patients remained at risk for temporary (OR 1.83 (1.15-2.93)) and permanent (OR 2.67 (1.16-6.16)) workforce withdrawal. Patients achieving on-treatment remission worked significantly more hours compared to non- and clinical responders and had lower unemployment-, sick-leave and disability pension rates both at baseline and after two years.</p><p><strong>Conclusion: </strong>Biologic therapy resulted in a modest increase in hours worked, yet patients remain at significant risk of early workforce withdrawal. Patients achieving remission had a stronger attachment to the workforce, also prior to biologic therapy.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1-11"},"PeriodicalIF":1.7,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143492137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Update on the Utilization of Complementary Therapies by Adolescents with Asthma in an Urban Population.","authors":"Gary K Soffer, Termeh Feinberg, Hillary Kroll, Marina Reznik","doi":"10.1080/02770903.2025.2475451","DOIUrl":"https://doi.org/10.1080/02770903.2025.2475451","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the prevalence and perceived efficacy of complementary and alternative medicine (CAM) use among urban adolescents with asthma, building on a previous landmark study, and to determine if CAM use varied by asthma severity, asthma control test (ACT), and non-CAM prescriptions for asthma treatment.</p><p><strong>Methods: </strong>An adapted survey was completed by 203 patients aged 13-18 years in outpatient specialty and primary care clinics in the Bronx, NY. Demographic information, adherence to prescription(s), ACT, and past year CAM utilization, perceived efficacy of CAM used, and substitution for prescription were assessed via self-report while severity, and related active prescriptions were derived through electronic health records. We conducted logistic regressions to determine if CAM use (yes/no) was associated with ACT (controlled/uncontrolled) or severity (persistent/intermittent).</p><p><strong>Results: </strong>82% of participants utilized at least one form of CAM in the management of their asthma. Mind-body (65%) and natural products (63%) were the most frequent with highest reported perceived efficacy (81%). Only 35% of patients discussed CAM use with their provider. ACT did not vary by CAM use (AOR: 1.57; 95%CI: 0.59, 4.15; p = 0.37), while prescription adherence was associated with a nearly seven-fold increase in CAM use (AOR: 7.79; 95%CI: 3.27, 18.54; p<.0001).</p><p><strong>Conclusions: </strong>The prevalence of CAM use amongst Bronx adolescents with asthma has likely largely remained stable since an initial 2002 analysis. Despite a lack of association between CAM use and asthma control, there was a high degree of perceived efficacy. Adolescents who use CAM for asthma management may do so as an overall component of health-promoting behavior such as prescription adherence.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1-13"},"PeriodicalIF":1.7,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamic property of central airway walls assessed by computed tomography: correlation with asthma pathophysiology.","authors":"Masafumi Yamaguchi, Akio Niimi, Hisako Matsumoto, Tetsuya Ueda, Masaya Takemura, Makiko Jinnai, Tsuyoshi Oguma, Yasutaka Nakano, Michiaki Mishima","doi":"10.1080/02770903.2025.2469312","DOIUrl":"10.1080/02770903.2025.2469312","url":null,"abstract":"<p><strong>Objective: </strong>A subset of asthmatics suffers from frequent exacerbations. Various features of airway remodeling and the resultant elastic property of airway walls may play pathophysiological roles in these exacerbations. The aim of the study was to examine the collapsibility of airways and sputum biomarkers associated with airway remodeling with different frequencies of exacerbations.</p><p><strong>Methods: </strong>We studied 29 moderate-to-severe asthmatics classified by the number of exacerbations in the previous year as, ≤1: stable, <i>n</i> = 18; ≥2: difficult, <i>n</i> = 11, and 11 healthy controls (HC). The absolute wall area (Awa) and luminal area (Ai) of a segmental bronchus were measured by computed tomography at full inspiration (FI) and full expiration (FE). We examined the %change of Ai (a measure of airway collapsibility) and Awa (a possible measure of vascular/water contents in the airway wall) from FI to FE. Sputum biomarkers associated with fibrosis [TGF-β₁ and matrix metalloproteinase (MMP)-9/tissue inhibitors of metalloproteinase (TIMP)-1 molar ratio] and those associated with angiogenesis/edema [vascular endothelial growth factor (VEGF) and vascular permeability index (sputum/serum ratio of albumin levels)] were examined.</p><p><strong>Results: </strong>Airway collapsibility was greater in difficult asthmatics than in stable asthmatics and HC. Sputum TGF-β₁ levels were higher and MMP-9/TIMP-1 molar ratios were lower in stable asthmatics than in HC. Sputum VEGF levels and vascular permeability index were higher in difficult asthmatics than in HC.</p><p><strong>Conclusions: </strong>Collapsibility of thickened airway walls may determine their susceptibility to exacerbations. This may depend on the balance between fibrosis and angiogenesis/edema in the airways.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1-8"},"PeriodicalIF":1.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What is the role of asthma in obstructive sleep apnea? A narrative review.","authors":"Grace Oscullo, José Daniel Gómez-Olivas, Francisco Javier González-Barcala, Miguel Ángel Martínez-García","doi":"10.1080/02770903.2025.2469322","DOIUrl":"10.1080/02770903.2025.2469322","url":null,"abstract":"<p><strong>Introduction: </strong>Asthma and obstructive sleep apnea (OSA) are two of the most prevalent respiratory diseases in the world. Their high prevalence increases the probability of the two diseases coexisting by chance in a single individual, but in recent years, various studies have also shown a real one-to-one association between them.</p><p><strong>Data sources: </strong>PubMed. Keywords: asthma (title) and OSA (title) and apnea (title) and positive airway pressure and CPAP (title).</p><p><strong>Studies selection: </strong>All manuscript related to the relationship between asthma an OSA as well as its treatments in terms of pathophysiological, diagnostic, etiological, epidemiological and treatment points.</p><p><strong>Results: </strong>50% of asthmatic patients suffer from OSA and the adjusted risk of developing OSA in asthmatics is 2.5 times higher than in non-asthmatic individuals, especially in poorly controlled, more severe or longer-standing asthmatics. Several mechanisms have been postulated to explain this increase in OSA in asthmatics: obesity, gastro-esophageal reflux, rhinitis, nasal polyps, increased pharyngeal collapsibility due to mechanical, inflammatory or dynamic causes and, finally, the upper airway deposition of inhaled corticosteroids (IC) generating myopathy in the pharyngeal muscles (as occurs in the vocal cord muscles, resulting in dysphonia).</p><p><strong>Conclusions: </strong>Although both asthma and OSA are common diseases that can coexist in the same individual, a one-to-one association between the two diseases has been observed. The presence of asthma could generate or exacerbate a preexisting OSA. Caution is recommended in IC inhalation techniques in patients with OSA. The use of ultrafine particles with less pharyngeal deposition is recommended.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1-7"},"PeriodicalIF":1.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143483274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of the peripheral perfusion index in children with bronchial asthma.","authors":"Hatice Bayar Acik, Nuh Yilmaz, Ahmet Kan","doi":"10.1080/02770903.2025.2472355","DOIUrl":"10.1080/02770903.2025.2472355","url":null,"abstract":"<p><strong>Objective: </strong>Peripheral perfusion index (PI) is noninvasive method measuring peripheral blood volume in numerical form and indicating perfusion status. In this study, we have investigated whether the relationship between the measurements of PI and definition of bronchial asthma exacerbation classification and treatment.</p><p><strong>Methods: </strong>This prospective study included in aged 5-12 years children applied to the hospital between January 2020 and June 2020. They were divided into two groups as patients who presented bronchial asthma symptoms and the control group who were selected as children applied to the hospital for routine healthy child follow-up. The severity of the asthma exacerbations was evaluated. Before administering nebulizer therapy, vital signs, oxygen hemoglobin saturation and PI values were recorded. Appropriate nebulizer treatment was initiated for the severity of exacerbation and subsequent changes in the PI values were recorded.</p><p><strong>Results: </strong>Pretreatment PI values were higher in children with asthma than those in healthy children (<i>p</i> = 0.001). The PI measurements of the patients for diagnosing asthma exacerbation showed a statistically significant area under the ROC curve (<i>p</i> = 0.001), and AUC (0.842) values of the 2.25 cutoff point of the PI value were sufficiently high. In the ROC analysis conducted to determine the need for hospitalization in patients presented with asthma exacerbations, the area under the curve was statistically significant (<i>p</i> = 0.020), and AUC (0.830) values of the 3.25 cutoff point of the PI value were sufficiently high.</p><p><strong>Conclusions: </strong>The PI measured in patients presented with asthma symptoms may use a valuable parameter for the diagnosing of asthma exacerbations and making hospitalization decisions.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1-6"},"PeriodicalIF":1.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experiences of early adolescents with allergic asthma receiving online education from peers: a qualitative phenomenological study.","authors":"Pelin Karatas, Husniye Calisir, Pinar Uysal","doi":"10.1080/02770903.2025.2472353","DOIUrl":"10.1080/02770903.2025.2472353","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the experiences and opinions of adolescents aged 10-14 years with allergic asthma in Turkiye about the online asthma education they received from their peers.</p><p><strong>Methods: </strong>Eleven adolescents who had previously received peer education concerning asthma participated in this qualitative phenomenological study. These were asked semi-structured questions to evaluate peer education through a video chat program. Qualitative data were analyzed using N'Vivo (Version 12.5) software.</p><p><strong>Results: </strong>Four main themes and 12 sub-themes were identified in the light of the data obtained from the interviews. 'The importance of friends' theme (T1) was established for the sharing, listening to their thoughts, caring about their opinions, and taking their suggestions into consideration sub-themes. 'The comfort derived from being with peers' them (T2) was established for the facilitating learning, feeling not alone, feeling understood, and motivation for recovery sub-themes. The reliability of information' theme (T3) was established for the believing in the reliability of the information and applying the information learned sub-themes, and the 'opinions about the educator' theme (T4) for the experiences with peer educators and suggestions for peer educators sub-themes.</p><p><strong>Conclusions: </strong>The experiences and opinions of the adolescents with allergic asthma in this study were highly favorable regarding the education provided by their peers about the disease in an online environment.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1-10"},"PeriodicalIF":1.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of medical education combined with extended care on adherence to inhaled glucocorticoids and clinical effects in patients with bronchial asthma.","authors":"Jin Zhou, Xuhao Yang, Jiaqing Zhou, Maoyu Xiong, Li Wen","doi":"10.1080/02770903.2024.2410423","DOIUrl":"10.1080/02770903.2024.2410423","url":null,"abstract":"<p><strong>Objective: </strong>To observe the clinical efficacy of medical education combined with extended care in patients with bronchial asthma and its effect on adherence to inhaled glucocorticoids.</p><p><strong>Methods: </strong>Ninety-eight patients with bronchial asthma were divided into the control group and the experimental group, <i>n</i> = 49, by utilizing the random number table method. The control group was given routine education and care as well as routine out-of-hospital instructions, and the experimental group was given medical education and extended care based on the control group. Asthma disease knowledge mastery, asthma control, quality of life, medication adherence and lung function were compared between both groups, and the number of asthma attacks and re-hospitalizations were recorded.</p><p><strong>Results: </strong>The experimental group performed higher scores of health knowledge, asthma control test and quality of life, rate of complete adherence, forced expiratory volume in one second (FEV₁), peak expiratory flow rate, and FEV₁/forced vital capacity. The number of asthma attacks and the times of re-hospitalizations were lower in the experimental group (all <i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>Medical education combined with extended care can improve bronchial asthma patients' mastery of asthma disease knowledge, effectively control patients' conditions, enhance patients' quality of life and lung function, increase patients' adherence to inhaled glucocorticoids, and reduce the recurrence of bronchial asthma patients.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"492-499"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142347187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pioglitazone and asthma: a review of current evidence.","authors":"Georgios I Barkas, Nikolaos D Karakousis, Konstantinos I Gourgoulianis, Zoe Daniil, Nikolaos Papanas, Ourania S Kotsiou","doi":"10.1080/02770903.2024.2414342","DOIUrl":"10.1080/02770903.2024.2414342","url":null,"abstract":"<p><strong>Objective: </strong>This review aims to present existing evidence on the impact of pioglitazone, a thiazolidinedione class anti-diabetic drug, on asthma control and lung function, providing a comprehensive understanding of its potential as a treatment for asthma.</p><p><strong>Data sources: </strong>The review draws upon data from preclinical animal studies and clinical trials investigating the effects of pioglitazone on asthma, focusing on its role in reducing airway inflammation, hyperreactivity, and remodeling, and its impact on pulmonary function.</p><p><strong>Study selections: </strong>Relevant studies were selected based on their examination of pioglitazone's therapeutic effects in asthma, including both animal models and clinical trials involving human asthma patients.</p><p><strong>Results: </strong>Animal studies have suggested that pioglitazone could alleviate inflammation, airway hyperreactivity, and airway remodeling, thereby improving pulmonary function in asthma. However, clinical trials have not demonstrated significant therapeutic benefits, with minimal improvements observed in asthma control and lung function, and the presence of notable side effects.</p><p><strong>Conclusion: </strong>Despite promising preclinical data, the efficacy of pioglitazone in treating human asthma remains unproven, with safety concerns and limited clinical benefits observed in trials. Further research is needed to assess the safety and effectiveness of pioglitazone in asthma treatment and to explore its impact on other inflammatory mechanisms.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"365-375"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142380916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dried fruit, acetate, and asthma: a mediation Mendelian randomization analysis.","authors":"Yanjiang Yang, Xiaorui Wang, Wenwen Yang","doi":"10.1080/02770903.2024.2408284","DOIUrl":"10.1080/02770903.2024.2408284","url":null,"abstract":"<p><strong>Background: </strong>Asthma is a common chronic condition with increasing prevalence. Diet, including dried fruit consumption, has been linked to asthma risk, but the mechanisms remain unclear. This study investigates how dried fruit consumption affects asthma risk, focusing on acetate as a potential mediator.</p><p><strong>Methods: </strong>We used Mendelian Randomization (MR) to analyze the relationships between dried fruit intake, acetate levels, and asthma. We applied three MR methods-Inverse-Variance Weighted (IVW), Weighted Median (WM), and MR-Egger-to determine causal effects.</p><p><strong>Results: </strong>Dried fruit intake was inversely associated with asthma risk (IVW: β = -0.506, <i>p</i> = 0.0135) and positively associated with acetate levels (IVW: β = 0.269, <i>p</i> < 0.0001). Higher acetate levels were also linked to lower asthma risk (IVW: β=-0.361, <i>p</i> < 0.0001). Mediation analysis showed that acetate mediates approximately 19.22% of the effect of dried fruit on asthma risk.</p><p><strong>Conclusion: </strong>Dried fruit consumption reduces asthma risk, partly through increasing acetate levels. This acetate-mediated pathway accounts for about 20% of the effect, suggesting potential for dietary strategies in asthma prevention and management. Further research could enhance the understanding and applicability of these findings.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"410-415"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142287948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Asthma identified as a major risk factor for recurrent respiratory tract infections in children: a meta-analysis of 29 studies.","authors":"Xiang Wang, Kaiwen Zheng, Quan Zhang","doi":"10.1080/02770903.2024.2417989","DOIUrl":"10.1080/02770903.2024.2417989","url":null,"abstract":"<p><strong>Background: </strong>Recurrent respiratory tract infections (RRTIs) in children represent a significant clinical challenge. Although some studies have identified potential risk factors, a comprehensive and systematic overview is lacking.</p><p><strong>Objective: </strong>This analysis is carried out to provide more advanced evidence to guide future prevention and health care.</p><p><strong>Methods: </strong>This study (PROSPERO: CRD42024576464) was conducted in accordance with PRISMA guidelines. PubMed, Embase, Web of Science, and the Cochrane Library were searched for relevant studies published in English. Subgroup analysis, sensitivity analysis, and publication bias assessments were performed. Data analysis was conducted using Stata 17, and GRADE was employed to assess the quality of evidence. The risk factors identified in the positive results were discussed qualitatively.</p><p><strong>Results: </strong>A total of 29 studies covering 639,078 children were included. Some risk factors: asthma (OR = 3.08, 2.06-4.62), breastfeeding <6 months (OR = 1.26, 1.04-1.52), DCC: day care center (OR = 1.50, 1.16-1.93), have siblings (OR = 1.26, 1.00-1.59), ETS: Environmental tobacco smoke (OR = 1.13, 1.00-1.27), snoring (OR = 1.49, 1.16-1.93) got positive result.</p><p><strong>Conclusion: </strong>This analysis identifies several key risk factors for RRTIs in children, providing enhanced evidence for prevention and management strategies. In particular, asthma warrants closer attention, given its strong association with respiratory infections in pediatrics.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"386-403"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142466157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}