Journal of Asthma最新文献

{"title":"The usefulness of lung ultrasound in pediatric asthma: a comparative study.","authors":"Iva Topalušić, Ozana Hofmann Jaeger, Ana Tripalo Batoš, Josip Pejić, Ivan Pavić","doi":"10.1080/02770903.2025.2519096","DOIUrl":"10.1080/02770903.2025.2519096","url":null,"abstract":"<p><strong>Objective: </strong>Lung ultrasound (LUS) shows promise in the assessment of various lung diseases. There is insufficient data about its use in pediatric asthma. The aim of this study was to determine the ultrasound findings in different clinical scenarios of pediatric asthma.</p><p><strong>Methods: </strong>The cross-sectional study involved children aged 5-17 years. LUS was performed within four groups of patients: newly diagnosed asthma, well-controlled asthma, acute exacerbation requiring hospitalization and healthy controls. LUS findings were recorded as either present or absent for abnormal sonographic indicators in each of the six lung zones.</p><p><strong>Results: </strong>The study involved 130 children aged 5-17 years. The mean number of LUS findings was significantly higher in children with newly diagnosed asthma and at acute asthma exacerbation than in patients with well-controlled asthma and the control group (<i>p</i> < 0.001). 84% of children with newly diagnosed asthma, 28% of patients with well-controlled asthma and 95% of patients with acute exacerbation had positive LUS findings. Only 11% of healthy controls had positive LUS findings. Consolidations larger than 1 cm, more than 3 B lines in more than one lung field, pleural effusion, as well as pleural line abnormalities were only documented in newly diagnosed astma and asthma exacerbation.</p><p><strong>Conclusion: </strong>LUS shows different ultrasound patterns in different scenarios of pediatric asthma. Further studies are needed to determine its role in the diagnosis and monitoring of asthma in children.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1762-1767"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144284459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The risk factors for asthma in adolescents: a systematic review and meta-analysis.","authors":"Hoileong Lee, Linyan Tang, Xin Wen","doi":"10.1080/02770903.2025.2519106","DOIUrl":"10.1080/02770903.2025.2519106","url":null,"abstract":"<p><strong>Objective: </strong>To identify risk factors for asthma in adolescents and provide a reference for disease management.</p><p><strong>Methods: </strong>PubMed, Embase, Web of science and Cochrane library were searched from inception to November 1st, 2024. The quality was evaluated by using the Agency for Healthcare Research and Quality and the New Ottawa Scal. The range of scores for inclusion in the study was 7-9. Heterogeneous results were pooled using a random-effects model and reported as odds ratio (OR).</p><p><strong>Results: </strong>Fifteen studies comprising 73,314 participants were included. The results of forest map showed that a total of 12 risk factors were associated with asthma in adolescents. Previous hypersensitivity reaction (OR 2.87 [95% CI 2.50-3.31]; <i>p</i> < 0.001), history of family hypersensitivity reaction (OR 2.35 [95% CI 1.93-2.86]; <i>p</i> < 0.001), history of family asthma (OR 2.48 [95% CI 1.97-3.12]; <i>p</i> < 0.001), active smoking (OR 1.47 [95% CI 1.28, 1.69]; <i>p</i> < 0.001), exposure to secondhand smoke (OR 1.27 [95% CI 1.20-1.34]; <i>p</i> < 0.001), domestic animals (OR 1.21 [95% CI 1.13-1.29]; <i>p</i> < 0.001), outdoor pollution (OR 1.27 [95% CI 1.15, 1.41]; <i>p</i> < 0.001), and biofuel (OR 1.10 [95% CI 1.02-1.19]; <i>p</i> < 0.001), and obese/overweight (OR 1.26 [95% CI 1.13-1.40]; <i>p</i> < 0.001), private school (OR 1.82 [95% CI 1.52-2.18]; <i>p</i> < 0.001), and female (OR 1.21 [95% CI 1.11-1.32]; <i>p</i> < 0.001) were found to be correlated.</p><p><strong>Conclusions: </strong>This study may provide a reference to inform the development of preventive strategies and management of adolescent asthma.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1662-1677"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The dilemma of the asthmatic patient: fight with the help of drugs or escape to a healthier environment?","authors":"Giovanni Rolla","doi":"10.1080/02770903.2025.2513593","DOIUrl":"10.1080/02770903.2025.2513593","url":null,"abstract":"<p><p>Asthma is characterized by chronic airway inflammation that underlies exacerbations in response to environmental triggers. The notable change in the environment that has occurred in recent decades, both outdoor and indoor, has contributed to increasing the concentrations of substances considered toxic to epithelia, including the epithelium of the airways. Considering the importance of environmental triggers, an avoidance strategy for environmental triggers could be useful for improving asthma control with sparing use of medications. The purpose of this commentary is to provide evidence that avoidance of environmental triggers can help control asthma with a consequent saving of anti-asthma medications. This approach requires that monitoring of pollutants to which the patient is exposed becomes part of the patient evaluation as is the search for biomarkers of inflammatory response. Many observations have shown that reduced exposure to NOx, household cleaning products and fine particulate matter is able to improve asthma control. Equally important for the control of asthma were the remediation of houses with damp and mold. Greater consideration of the environmental triggers of asthma exacerbations can help the clinician further personalize the asthma treatment strategy. The message is to combine the immunophenotyping of asthma (T2 high vs. T2 low) with a sort of phenotyping of environmental triggers.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1656-1661"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of pediatric asthma severity using retrospective electronic health record prescription data: an analysis before and after the 2020 national asthma education and prevention program guideline update.","authors":"Jinqian Pan, Jie Xu, David Fedele, Yonghui Wu, Jennifer Brailsford, Jennifer Fishe","doi":"10.1080/02770903.2025.2514265","DOIUrl":"10.1080/02770903.2025.2514265","url":null,"abstract":"<p><strong>Objective: </strong>Development of a feasible, accurate method to assess pediatric asthma severity would benefit clinical care and research. This study sought to determine pediatric asthma severity from retrospective electronic health record prescription data, and to compare severities before and after the 2020 National Asthma Education and Prevention Program (NAEPP) guideline update.</p><p><strong>Methods: </strong>This retrospective analysis included patients ages 2 - 18 years of age from a large, multi-center healthcare provider. We assessed severity by mapping asthma-related medication prescriptions with NAEPP step-up therapy guidelines. We compared severities between the 2007 NAEPP guideline (2011-2020) and 2020 NAEPP guideline (2021-2023) periods.</p><p><strong>Results: </strong>We identified 55,818 pediatric asthma patients with a median age of 7.5 years. Overall, were either mild intermittent (41.6%) or mild persistent severity (34.9%), followed by 9.7% moderate persistent and 4.8% severe persistent severity. From the 2007 to 2020 NAEPP period, there was <i>a</i> ∼5% decrease in mild persistent and moderate persistent severity, and a large increase in undefined severity from 7.0% to 19.6% after the 2020 NAEPP update.</p><p><strong>Conclusions: </strong>This study's approach using outpatient medication prescription data to determine pediatric asthma severity according to NAEPP guidelines classified over 90% of patients. After the 2020 NAEPP guideline update, we found decreases in the proportion of children having mild and moderate persistent severity, and a large increase in patients for whom severity could not be determined due to off-label prescriptions. Mapping pediatric asthma severity through medication prescriptions is feasible, but further work is required to understand off-label prescribing patterns in pediatric asthma.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1729-1739"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12287910/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mucoid impaction due to broncholithiasis with a clinical presentation mimicking allergic bronchopulmonary aspergillosis.","authors":"Michihiro Kunishige, Hiroki Takahashi, Kiyohide Takahashi, Miho Nishiyama, Kenya Sumitomo, Tsutomu Shinohara","doi":"10.1080/02770903.2025.2513063","DOIUrl":"10.1080/02770903.2025.2513063","url":null,"abstract":"<p><strong>Introduction: </strong>Imaging evaluation of mucoid impaction is important in differentiating allergic bronchopulmonary aspergillosis (ABPA) from other severe asthma cases with or without fungal sensitization.</p><p><strong>Case report: </strong>We encountered a case of mucoid impaction in a 62-year-old man with severe asthma who was positive for anti-<i>Aspergillus</i> IgG antibodies; however, subsequent examination revealed that the cause of wheezing and mucoid impaction was broncholith. While broncholiths can be a direct cause of wheezing due to the associated airway narrowing, mucosal damage caused by broncholiths or fungi attached to them may be an exacerbating factor for asthma. Moreover, mucoid impaction is actually a rare manifestation of broncholiths.</p><p><strong>Conclusions: </strong>Broncholithiasis should be considered in the differential diagnosis of ABPA and other conditions involving mucoid impaction.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1825-1830"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parental numeracy skills and asthma control: a cross-sectional study.","authors":"Walid Al-Qerem, Anan Jarab, Abdel Qader Al Bawab, Judith Eberhardt, Enas Al-Zayadnehe, Montaha Al-Iede, Maher Khdour, Lujain Al-Sa'di, Lama Sawaftah","doi":"10.1080/02770903.2025.2519100","DOIUrl":"10.1080/02770903.2025.2519100","url":null,"abstract":"<p><strong>Objective: </strong>Asthma is a common chronic condition among children globally, with increasing prevalence in Jordan. Effective asthma control depends on parental involvement, including numeracy skills, which influence medication management and symptom monitoring. This study investigated the association between parental numeracy and asthma control in Jordanian children.</p><p><strong>Methods: </strong>A cross-sectional study was conducted with 400 parents of children with asthma receiving treatment at the University of Jordan Hospital between February and May 2024. Participants were recruited from clinic waiting areas. Parental numeracy was assessed using the Arabic version of the Asthma Numeracy Questionnaire (Ar-ANQ). The sample included 59.5% male children (median age = 6 years; IQR: 3-11) and 54.1% female parents (median age = 37 years; IQR: 31-43).</p><p><strong>Results: </strong>Higher parental numeracy scores were significantly associated with better asthma control (Coefficient = 0.236, 95% CI [0.056, 0.417], <i>p</i> = 0.01). Low monthly income and older parental age were negatively associated with asthma control (<i>p</i> = 0.034 and <i>p</i> = 0.004, respectively). Poor medication adherence also correlated with lower asthma control (<i>p</i> = 0.025).</p><p><strong>Conclusions: </strong>Parental numeracy significantly affects asthma control in children. Improving numeracy skills and medication adherence, especially in low-income families, could enhance asthma outcomes. Future research should explore long-term interventions to address these factors and improve asthma management in Jordan.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1768-1775"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144284458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High- <i>vs.</i> low-intensity inspiratory muscle training in asthma: effects on respiratory muscles, exercise performance, dyspnea, and health-related quality of life.","authors":"Cahidenur Kocak, Esra Pehlivan, Seyma Baslilar","doi":"10.1080/02770903.2025.2519103","DOIUrl":"10.1080/02770903.2025.2519103","url":null,"abstract":"<p><strong>Objective: </strong>To compare the effects of high- and low-intensity Inspiratory Muscle Training (IMT) combined with standard pulmonary rehabilitation on respiratory muscle function, exercise capacity, dyspnea, and quality of life in asthmatic patients.</p><p><strong>Methods: </strong>Forty asthmatic patients were randomized into high-intensity IMT (H-IMT, <i>n</i> = 20) and low-intensity IMT (L-IMT, <i>n</i> = 20) groups. The H-IMT group trained at 80% of maximal inspiratory pressure and the L-IMT group at 30%, with 5% weekly load increases. Both groups followed an 8-week exercise program including breathing, strengthening, and walking exercises. Respiratory functions, pulmonary function test, respiratory muscle strength, maximum inspiratory and expiratory pressure measurement, peripheral muscle strength, 6-min walk test (6MWT), modified Medical Research Council (mMRC) dyspnea and Asthma Control Test (ACT), Asthma Quality of Life Questionnaire (AQLQ), Saint George Respiratory Quality of Life Questionnaire (SGRQ) and International Physical Activity Questionnaire (IPAQ) scores were assessed pre- and post-intervention.</p><p><strong>Results: </strong>Baseline characteristics were similar. Both groups improved in most outcomes except spirometric values. The L-IMT group showed significant gains in IPAQ-SF walking (<i>p</i> = .03) and total scores (<i>p</i> = .02). 6MWT distance, mMRC, and ACT scores improved significantly more in the H-IMT group compared to the L-IMT group. There was no statistically significant difference between the groups (<i>p</i> > 0.05). Similarly, when the groups were compared, AQLQ-Environmental, AQLQ-Total, SGRQ-Impact, SGRQ-Total scores showed more improvement in the H-IMT group.</p><p><strong>Conclusion: </strong>Both IMT intensities improved respiratory function, exercise capacity, and quality of life. High-intensity IMT was more effective for asthma control, while low-intensity IMT enhanced physical activity. Tailoring IMT intensity may optimize outcomes for asthmatic patients.</p><p><strong>Registration number: </strong>NCT06516848.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1776-1788"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcriptome sequencing analysis identified an alternative splicing regulatory network mediated by RNA-binding proteins in asthma.","authors":"Jingyi Zhang, Mengqi Wang, Dongxiao Yu, Changjie Qu, Jialin Zhang, Huimin Lao","doi":"10.1080/02770903.2025.2526365","DOIUrl":"10.1080/02770903.2025.2526365","url":null,"abstract":"<p><strong>Background: </strong>Accelerated eosinophilic apoptosis is an important therapeutic strategy for bronchial asthma (BA).</p><p><strong>Objective: </strong>To further reveal the molecular mechanism.</p><p><strong>Methods: </strong>We selected RNA-seq data from cells in bronchoalveolar lavage fluid from patients with different severity levels. we performed principal component analysis (PCA) of the splicing ratios of differentially expressed genes (DEGs) between different samples. And we carried out overlapping analysis of DEGs in samples with known RBP genes. Then we analyzed the GO functions of the differentially expressed AS genes regulated by the differential expression of RBPs. We also analyzed the RBP-AS-GO network and analyzed RBPs and genes known to be involved in apoptosis and inflammation. Finally, we selected another set of data to verify the results.</p><p><strong>Results: </strong>we identified nine highly expressed alternative splicing events, among which A3SS and A5SS had the highest incidence. The incidence of these alternative splicing events (ASEs) is closely related to the severity of BA. And we identified nine important RNA-binding proteins (RBPs). We obtained some AS genes were enriched in apoptosis- and inflammation-related pathways. Then we analyzed RBPs and genes known to be involved in apoptosis and inflammation. The results revealed that the expression levels of the selected RBPs were consistent in the two datasets and that the rate of AS events in both genes was increased.</p><p><strong>Conclusion: </strong>We hypothesized that the regulation of AS by RBPs could affect apoptosis and inflammation in patients with severe asthma. We predicted that RBPs (PCBP4 and RPS29) and ASEs (A5SSs) are potential therapeutic targets for BA.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1798-1806"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144560213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stock inhalers in action: results of a pilot study across multiple Illinois counties.","authors":"Andrea A Pappalardo, Paige Hardy, Caroline Youssef, Lynn B Gerald, Molly A Martin","doi":"10.1080/02770903.2025.2519095","DOIUrl":"10.1080/02770903.2025.2519095","url":null,"abstract":"<p><strong>Objective: </strong>Pediatric asthma health disparities are common. Schools often lack asthma diagnostic information and infrastructure to handle asthma symptoms. Undesignated or stock rescue inhalers available to anyone in respiratory distress can help prevent absences.</p><p><strong>Methods: </strong>A stock inhaler pilot program was conceptualized and evaluated using implementation science frameworks. Districts from high-asthma-burden counties were engaged and offered guided implementation over the 2022-2023 or 2023-2024 school year. Districts were required to complete training and report stock inhaler incidents. Pre/post implementation interviews and surveys were performed to assess acceptability, feasibility, fidelity to emergency protocols, satisfaction, and utilization. Descriptive statistics were calculated for surveys and utilization data. Thematic data analysis was performed on interview transcripts.</p><p><strong>Results: </strong>Fourteen pilot schools from six districts served 10,265 children. Twenty-eight stock inhaler events were documented. The majority of children (75%) using the stock inhaler had known asthma. Of the 24 events for which disposition was reported, 12 students returned to class (50%), 10 left school with a parent (42%), and only two were transported by emergency services (8%). Pre-implementation interviews revealed that school nurses were concerned about family asthma education (76%) and staff training (29%). One interviewee described the program as \"a sturdy safety net… if you can't breathe, nothing else matters\". All schools intended to continue stocking inhalers.</p><p><strong>Conclusions: </strong>Stock inhaler programming was well received and improved student outcomes. Resources for Every School Confronting Unexpected Emergencies-Illinois (RESCUE-IL) secured state funding in Illinois to expand stock inhaler programming to over 80% of Illinois public schools. Multi-level, community-focused interventions can maximize the impact of health policies.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1752-1761"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of asthma exacerbations in pediatric emergency departments across the United States.","authors":"Melisa S Tanverdi, Isabella Zaniletti, Nidhya Navanandan, Isabel Hardee, Andrew H Liu, Rakesh D Mistry","doi":"10.1080/02770903.2025.2513056","DOIUrl":"10.1080/02770903.2025.2513056","url":null,"abstract":"<p><strong>Objectives: </strong>There are 750,000 emergency department (ED) visits by children for asthma exacerbations in the United States annually. Despite changing evidence and epidemiology, there have not been recent assessments of acute asthma prevalence, management, and outcomes from pediatric EDs. This 40-center retrospective evaluation utilizes the Pediatric Hospital Information System to characterize pediatric ED asthma presentations from 2015-2020.</p><p><strong>Study design: </strong>Children 2-18 years with asthma ICD-9/10 code and receipt of albuterol were included. Demographics, Child Opportunity Index (COI), ED management, return visits, and adjusted costs were evaluated. Data were summarized using standard descriptive statistics and trends assessed using Mann-Kendall trend test.</p><p><strong>Results: </strong>There were 414,264 encounters made by 256,209 unique patients; 21% had >1 visit in 12 months. Median age was 6 years, 61.6% male, 44.5% Black, and 68.5% publicly insured; 58.3% of visits were by patients with very low/low COI. Systemic corticosteroids were administered in 86.3% of visits; 52.7% used dexamethasone. Chest radiographs were obtained in 23% of encounters. Most (74.9%) encounters resulted in ED discharge with a downward trend of visits for exacerbations per 1,000 ED visits of -9.77, 95% CI [-9.99,-9.54], increase in disposition to intensive care unit of 2.01 [1.87,2.41] and decrease in home/other of -3.77 [-4.34,-3.20]. There was no significant trend in return visits. Total adjusted costs were ∼$900 million.</p><p><strong>Conclusions: </strong>ED visits for asthma remain frequent and disproportionately affect children with lower social determinants of health. Dexamethasone has not been widely adopted as corticosteroid of choice and use of ancillary testing continues, highlighting opportunities for improvement in asthma care.</p>","PeriodicalId":15076,"journal":{"name":"Journal of Asthma","volume":" ","pages":"1651-1655"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144187089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}