Journal of Biotechnology and Biomedicine最新文献_第3页

Biomechanical Forces in the Tissue Engineering and Regeneration of Shoulder, Hip, Knee, and Ankle Joints 组织工程和肩关节、髋关节、膝关节和踝关节再生中的生物力学力

Journal of Biotechnology and Biomedicine Pub Date : 2023-01-01 DOI: 10.26502/jbb.2642-91280111

Merlin Rajesh Lal LP, Devendra K Agrawal

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Ways to Improve Workflow and Morale in an Ophthalmology Clinic: Survey Advice from Clinic Staff 如何改善眼科诊所的工作流程和士气:来自诊所工作人员的调查建议

Journal of Biotechnology and Biomedicine Pub Date : 2023-01-01 DOI: 10.26502/jbb.2642-91280108

Rebekah C Smith, Terisa Yiin, Cindy Monelavongsy, Cherrie Soledad Tan, Marta Rodriguez, Michele Lim, Yin Allison Liu

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Vinci Power Nap® Synchronization Technology - Neuroarchitecture for better sleep, adding Energy for Life, Reducing Stress and Jet Lag, Improving Wellbeing and Body-Mind Regeneration. Helpful for Leaders, Doctors, Soldiers, Children, Drivers, Pilots, Astronauts, People Traveling On Earth And Beyond Vinci Power Nap®同步技术-改善睡眠的神经结构，为生活增添能量，减少压力和时差，改善健康和身心再生。有助于领导，医生，士兵，儿童，司机，飞行员，宇航员，人们在地球上旅行和超越

Journal of Biotechnology and Biomedicine Pub Date : 2023-01-01 DOI: 10.26502/jbb.2642-91280076

Magdalena Filcek

{"title":"Vinci Power Nap® Synchronization Technology - Neuroarchitecture for better sleep, adding Energy for Life, Reducing Stress and Jet Lag, Improving Wellbeing and Body-Mind Regeneration. Helpful for Leaders, Doctors, Soldiers, Children, Drivers, Pilots, Astronauts, People Traveling On Earth And Beyond","authors":"Magdalena Filcek","doi":"10.26502/jbb.2642-91280076","DOIUrl":"https://doi.org/10.26502/jbb.2642-91280076","url":null,"abstract":"The Vinci Power Nap® neurotechnological system created for energy naps, which can benefits mankind on Earth and in space travels. This cutting edge tool helping to reduce stress, jet lag, regulating the circadian rhythm, improving focus, efficiency, reaction times, preventing losing bone mass, the quality of sleep, health and human wellbeing in future smart cities and Lunar, Martian habitats. The remarkable results can be found in studies on UN Delegates at COP24, UNICEF project for war traumatized refugees women and children, soldiers with PTSD, pilots and analog astronauts, showing the healing power of touching, frequency of rocking, napping in a zero gravity position. Good sleep is needed to reset, recover, strengthen the immune system, also avoid errors resulting from fatigue and jet lag, which is especially important for business leaders, doctors, drivers, athletes, students, soldiers, pilots, astronauts and tourists. The frequency of the VPN technology pendulum movement is a revolution in the synchronization of breathing, heartbeat, delta waves in the brain, during which the best regeneration of the body and mind occurs. Moreover, the pulsating pressure on the skin increase the level of hormones: dopamine, oxytocin, serotonin, etc. All this contributes to the regeneration of sleep and energy, improving human’s psychophysical condition, longevity and advances in sleep and space medicine.","PeriodicalId":15066,"journal":{"name":"Journal of Biotechnology and Biomedicine","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87761299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of the Interaction of Citric Acid and Drought on the Growth of Spotted Gum (Corymbia Maculata) Seedlings 柠檬酸与干旱互作对斑胶幼苗生长的影响

Journal of Biotechnology and Biomedicine Pub Date : 2023-01-01 DOI: 10.26502/jbb.2642-91280097

Mark Burns

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Risk Factors for Low Birth Weight among Neonates Delivered in Public Health Facilities in Adama Town, Oromia Regional State, Ethiopia 埃塞俄比亚奥罗米亚地区州Adama镇公共卫生设施中新生儿出生体重过低的危险因素

Journal of Biotechnology and Biomedicine Pub Date : 2023-01-01 DOI: 10.26502/jbb.2642-91280102

Nigusse Obse Nebi, Tolossa Eticha Chaka, Tilaye Workineh Abebe, Ephrem Mannekulih M

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Accelerating Minimap2 for Accurate Long Read Alignment on GPUs. 在 GPU 上加速 Minimap2 以实现精确的长读数配准。

Journal of Biotechnology and Biomedicine Pub Date : 2023-01-01 Epub Date: 2023-01-20 DOI: 10.26502/jbb.2642-91280067

Harisankar Sadasivan, Milos Maric, Eric Dawson, Vishanth Iyer, Johnny Israeli, Satish Narayanasamy

{"title":"Accelerating Minimap2 for Accurate Long Read Alignment on GPUs.","authors":"Harisankar Sadasivan, Milos Maric, Eric Dawson, Vishanth Iyer, Johnny Israeli, Satish Narayanasamy","doi":"10.26502/jbb.2642-91280067","DOIUrl":"10.26502/jbb.2642-91280067","url":null,"abstract":"<p><p>Long read sequencing technology is becoming increasingly popular for Precision Medicine applications like Whole Genome Sequencing (WGS) and microbial abundance estimation. Minimap2 is the state-of-the-art aligner and mapper used by the leading long read sequencing technologies, today. However, Minimap2 on CPUs is very slow for long noisy reads. ~60-70% of the run-time on a CPU comes from the highly sequential chaining step in Minimap2. On the other hand, most Point-of-Care computational workflows in long read sequencing use Graphics Processing Units (GPUs). We present minimap2-accelerated (mm2-ax), a heterogeneous design for sequence mapping and alignment where minimap2's compute intensive chaining step is sped up on the GPU and demonstrate its time and cost benefits. We extract better intra-read parallelism from chaining without losing mapping accuracy by forward transforming Minimap2's chaining algorithm. Moreover, we better utilize the high memory available on modern cloud instances apart from better workload balancing, data locality and minimal branch divergence on the GPU. We show mm2-ax on an NVIDIA A100 GPU improves the chaining step with 5.41 - 2.57X speedup and 4.07 - 1.93X speedup : costup over the fastest version of Minimap2, mm2-fast, benchmarked on a Google Cloud Platform instance of 30 SIMD cores.</p>","PeriodicalId":15066,"journal":{"name":"Journal of Biotechnology and Biomedicine","volume":"6 1","pages":"13-23"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10018915/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9508766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploratory Study of Risk Factors for Congenital Malformations in Morocco 摩洛哥先天性畸形危险因素的探索性研究

Journal of Biotechnology and Biomedicine Pub Date : 2023-01-01 DOI: 10.26502/jbb.2642-91280105

K Forci, E Bouaiti, MH Alami, A Mdaghri Alaoui, A Thimou Izgua

引用次数: 0

Telomere Dynamics, Gene Expression and Genetic Instability in Glioblastoma Cells Treated with Reversine 逆转录酶治疗胶质母细胞瘤细胞的端粒动力学、基因表达和遗传不稳定性

Journal of Biotechnology and Biomedicine Pub Date : 2023-01-01 DOI: 10.26502/jbb.2642-91280118

Fábio Morato de Oliveira, Aline Monezi Montel, Wagner Gouvêa dos Santos

引用次数: 0

cProSite: A Web Based Interactive Platform for Online Proteomics, Phosphoproteomics, and Genomics Data Analysis cProSite:基于Web的在线蛋白质组学、磷蛋白质组学和基因组学数据分析的交互平台

Journal of Biotechnology and Biomedicine Pub Date : 2023-01-01 DOI: 10.26502/jbb.2642-91280119

Dunrui Wang, Xiaolan Qian, Yi-Chieh Nancy Du, Beatriz Sanchez-Solana

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Extracellular Matrix Glycoprotein Thrombospondin 1: An Overlooked Pathological Mediator in Vasculopathy of Systemic Sclerosis-Secondary Raynaud’s Phenomena 细胞外基质糖蛋白-血小板反应蛋白1:在系统性硬化症-继发性雷诺现象血管病变中被忽视的病理介质

Journal of Biotechnology and Biomedicine Pub Date : 2023-01-01 DOI: 10.26502/jbb.2642-91280093

Zulfa Allaf, Megan Yao

{"title":"Extracellular Matrix Glycoprotein Thrombospondin 1: An Overlooked Pathological Mediator in Vasculopathy of Systemic Sclerosis-Secondary Raynaud’s Phenomena","authors":"Zulfa Allaf, Megan Yao","doi":"10.26502/jbb.2642-91280093","DOIUrl":"https://doi.org/10.26502/jbb.2642-91280093","url":null,"abstract":"Systemic sclerosis (SSc) is an autoimmune connective tissue disorder characterized by a widespread vasculopathy, autoimmunity, and fibrosis of the skin and internal organs such as the lung and kidneys. Raynaud's phenomenon is the earliest recognized symptom of SSc. Unlike the primary Raynaud's disease, the condition responds well to management with non-pharmacological measures and pharmacological agents, Raynaud's phenomenon presented complex and progressive vasculopathy in the superficial vasculature embedded under the skin. The mechanisms underlying the development and progress of Raynaud's phenomenon are still unclear. Repeated Raynaud's phenomenon attacks are characteristic of ischemia-reperfusion episodes with different durations. What occurred to the superficial vascular bed highly possibly replicates at the vasculature in the vulnerable internal organ(s) at a later time and a distinctive pace. Elevated extracellular matrix glycoprotein thrombospondin 1 (TSP1) levels are found in circulation and throughout the skin in patients with SSc. TSP1-mediated vascular pathologies have been extensively investigated in multiple conditions, including hypertension, pulmonary arterial hypertension, and renal ischemia-reperfusion injury. TSP1 vasculopathy in these conditions is evidenced by a variety of function-modulating and vascular remodeling effects, specifically enhancing vasoconstrictive tone, platelet hyperaggregation, and inflammatory cell infiltration, inducing capillary rarefaction and promoting intimal thickening. In addition, the well-known anti-angiogenic property of TSP1 significantly impairs the self-repair and self-renewal capacity of growth factor-or stem cell-based regenerative therapies. Thanks to the growing knowledge of TSP1 vasculopathy in affected internal organs and adverse effects on regrowth, it is proposed that pathological levels of TSP1 may exert a similar pattern of multifaceted effects on the vasculature in SSc and regenerative therapies under investigation.","PeriodicalId":15066,"journal":{"name":"Journal of Biotechnology and Biomedicine","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83871546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0