Journal of Advances in Medicine Science最新文献_第4页

The Progress of the General Prevention and Treatment of Pediatric Caries in China 中国儿童龋齿综合防治进展

Journal of Advances in Medicine Science Pub Date : 2019-04-11 DOI: 10.30564/JAMS.V2I2.601

Jinping Liu

引用次数: 0

FOXM1 and UBE2C Are Distinct Biomarkers for Non-Small Cell Lung Cancer Survival Prediction: Data-Mining Based on ONCOMINE FOXM1和UBE2C是非小细胞肺癌生存预测的独特生物标志物:基于ONCOMINE的数据挖掘

Journal of Advances in Medicine Science Pub Date : 2019-04-11 DOI: 10.30564/JAMS.V2I2.611

Ya Wang, Jiang Zhu

{"title":"FOXM1 and UBE2C Are Distinct Biomarkers for Non-Small Cell Lung Cancer Survival Prediction: Data-Mining Based on ONCOMINE","authors":"Ya Wang, Jiang Zhu","doi":"10.30564/JAMS.V2I2.611","DOIUrl":"https://doi.org/10.30564/JAMS.V2I2.611","url":null,"abstract":"Non-small cell lung cancer (NSCLC) remains to be primary reason of tumor deaths in the past few decades. The mortality of this malignancy could be reduced by developing new prognostic biomarkers and discovering novel therapeutic biological target. Here, we studied the mRNA expression of FOX gene family and UBE2C in different types of cancer compared with normal tissue through ONCOMINE differential analysis. CCLE analysis was mined to explore the expression profiles of target genes in different tumor cells. GEPIA was used to discover the expression of target genes in different subtypes and the correlation with lung cancer stage. The prognostic values of FOXM1 and UBE2C were further investigated through Kaplan-Meier plotter analysis. It showed that FOXA1, FOXD1 and FOXM1 were dramatically high expressed in NSCLC comparing with normal lung tissues. Besides, the expression of FOXM1 was significantly associated with UBE2C. Furthermore, the overexpression of FOXM1 and UBE2C were correlated to shorter survival in lung adenocarcinoma (LAC) instead of lung squamous cell carcinoma(LSCC).Hence, we could draw a conclusion that FOXM1 and UBE2C are distinguished biomarkers and crucial prognostic indicators for lung adenocarcinoma patients.","PeriodicalId":14958,"journal":{"name":"Journal of Advances in Medicine Science","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86667457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-chain Brønsted Acidic Ionic Liquids Catalyzed one-pot three-component Biginelli Reaction under Solvent-Free Conditions 长链Brønsted酸性离子液体在无溶剂条件下催化一锅三组分Biginelli反应

Journal of Advances in Medicine Science Pub Date : 2019-03-12 DOI: 10.30564/JAMS.V2I2.535

Leqin He

引用次数: 0

Effects of Exercise on the Pharmacokinetics of Icariin II in Rats 运动对淫羊藿苷ⅱ在大鼠体内药动学的影响

Journal of Advances in Medicine Science Pub Date : 2019-01-11 DOI: 10.30564/JAMS.V2I1.161

X. Kong

引用次数: 0

Effect of Emergency Care Process Optimization on Rescue Efficiency of Emergency Patients 急诊护理流程优化对急诊患者抢救效率的影响

Journal of Advances in Medicine Science Pub Date : 2019-01-11 DOI: 10.30564/jams.v2i1.244

Huifei Wang

{"title":"Effect of Emergency Care Process Optimization on Rescue Efficiency of Emergency Patients","authors":"Huifei Wang","doi":"10.30564/jams.v2i1.244","DOIUrl":"https://doi.org/10.30564/jams.v2i1.244","url":null,"abstract":"This paper discusses the impact of emergency care process optimization on the rescue efficiency of emergency patients. Methods: 102 cases of emergency patients received from January 2017 to February 2018 in our hospital were selected as research objects. According to the order of treatment, they were divided into control group and observation group. The routine nursing process was given to the control group, and the observation group was given an optimized nursing process to compare the rescue efficiency and nursing satisfaction of the two groups. Results: According to the results of the study, the nursing satisfaction of the two groups was compared. Among them, the total satisfaction of the observation group was 49, accounting for 96.07%; the control group was very satisfied with the nursing work, accounting for 82.35%. There was a significant difference in nursing satisfaction between the two groups, which was statistically significant (P<0.05). Comparing the rescue efficiency of the two groups of patients, the observation time, rescue time, infusion time and disease remission time were significantly lower than the control group, the rescue success rate was 94.11%, and the rescue success rate of the control group was 78.43%. The results have statistical significance (P < 0.05). Conclusion: The optimization of emergency nursing process can greatly improve the rescue efficiency of emergency patients, reduce the disability rate and mortality, improve the quality of nursing, and enhance the satisfaction of nursing. It is worthy of clinical promotion practice.","PeriodicalId":14958,"journal":{"name":"Journal of Advances in Medicine Science","volume":"74 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83981547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study on the Effect of High Quality Nursing on the Compliance of Patients with Chronic Hepatitis B 优质护理对慢性乙型肝炎患者依从性的影响研究

Journal of Advances in Medicine Science Pub Date : 2019-01-11 DOI: 10.30564/JAMS.V2I1.429

Huiling Yang

引用次数: 1

Effects of Xuezhikang (Red Yeast Rice) on Blood lipids, Hemorheology and the Expression of P65 and Tissue Factor in Atherosclerotic Rats 血脂康对动脉粥样硬化大鼠血脂、血液流变学及P65和组织因子表达的影响

Journal of Advances in Medicine Science Pub Date : 2019-01-11 DOI: 10.30564/JAMS.V2I1.318

Ya-bing Yang, Mei-lin Liu

{"title":"Effects of Xuezhikang (Red Yeast Rice) on Blood lipids, Hemorheology and the Expression of P65 and Tissue Factor in Atherosclerotic Rats","authors":"Ya-bing Yang, Mei-lin Liu","doi":"10.30564/JAMS.V2I1.318","DOIUrl":"https://doi.org/10.30564/JAMS.V2I1.318","url":null,"abstract":"Objective: To observe the effects of Xuezhikang (red yeast rice) on blood lipids, blood rheology, and expression of P65 and tissue factor, and to explore the anti-atherosclerosis effect and related mechanisms of Xuezhikang (red yeast rice). Methods: 32 Wistar rats were randomly divided into normal control group, Xuezhikang treatment group, lovastatin treatment group and atherosclerosis model group (8 in each group). blood lipids, blood rheology, malondialdehyde (MDA), total antioxidant capacity (t-AOc), and expression of aortic tissue factor (tF) and P65 were measured in each group. results: (1) Both Xuezhikang and lovastatin could reduce blood lipid levels, but there was no significant difference between the two groups; (2) Both Xuezhikang and lovastatin can improve the hemorheology of atherosclerotic rats, but the difference between the two groups is not signifcant; (3) Compared with lovastatin, Xuezhikang inhibited the expression of TF and P65 in aorta of rats with atherosclerosis; (4) Compared with lovastatin, the Xuezhikang group had lower MDA levels and higher T-AOC. Conclusion: Xuezhikang can improve blood lipid levels and hemorheology in rats with atherosclerosis. Compared with lovastatin, Xuezhikang has stronger effects on inhibiting oxidative stress and down-regulating the expression of tissue factor and P65.","PeriodicalId":14958,"journal":{"name":"Journal of Advances in Medicine Science","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84583691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Discussion on Health Management Model of Patients with Chronic Diseases 慢性病患者健康管理模式探讨

Journal of Advances in Medicine Science Pub Date : 2019-01-11 DOI: 10.30564/jams.v2i1.157

L. Duan

引用次数: 0

Aloe Royal Jelly Powder Contributes to Maintain Normal Immunity: a Randomized Clinical Trial 芦荟蜂王浆粉有助于维持正常免疫力:一项随机临床试验

Journal of Advances in Medicine Science Pub Date : 2018-11-22 DOI: 10.30564/jams.v1i4.293

Yi Yang, Chen Zhang, X. Zhu, Mei Huang, Xuemei Wang, Xiaotong Liu, Qian Liu, Fen Zhang, Weiwei Li

{"title":"Aloe Royal Jelly Powder Contributes to Maintain Normal Immunity: a Randomized Clinical Trial","authors":"Yi Yang, Chen Zhang, X. Zhu, Mei Huang, Xuemei Wang, Xiaotong Liu, Qian Liu, Fen Zhang, Weiwei Li","doi":"10.30564/jams.v1i4.293","DOIUrl":"https://doi.org/10.30564/jams.v1i4.293","url":null,"abstract":"To study the safety and the function of maintaining normal immunity of product with royal jelly lyophilized powder and whole-leaf aloe drying powder as main raw materials. Methods: Selected 125 subjects qualified for inclusion/exclusion criteria for a trial test. (The trial group lost 9 subjects. The control group lost 6 subjects.54 effective subjects of trial group includes 12 men and 42 women. 56 effective subjects of control group including 9 men and 47 women.) The trial group was evaluated by self-control and inter-group comparison, after 90 days of continuous use of aloe royal jelly. Results: There are significant differences in the overall feeling, physiological feeling, psychological feeling and comprehensive evaluation of the individuals in the trial group after 90 days (P<0.001), which are higher than before. The control group has no statistically significant difference in the comprehensive evaluation before and after the trial (P>0.05). The ratio of CD4/CD8, IgG, IgA and IgM in the trial group and the placebo control group are above the normal low-limit. There is no obvious abnormality in indicators of blood test, blood biochemistry, liver and kidney function and other clinical tests. Conclusion: Aloe royal jelly powder contributes to maintain normal immune function and has no harmful effect to the health of subjects.","PeriodicalId":14958,"journal":{"name":"Journal of Advances in Medicine Science","volume":"101 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79400960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Latest Advances in the Treatment of Post-stroke Limb Spasm with Botulinum Neurotoxin 肉毒杆菌神经毒素治疗中风后肢体痉挛的最新进展

Journal of Advances in Medicine Science Pub Date : 2018-11-22 DOI: 10.30564/JAMS.V1I4.294

Shuhua Chen, Lingjing Jin

引用次数: 0