{"title":"运动对淫羊藿苷ⅱ在大鼠体内药动学的影响","authors":"X. Kong","doi":"10.30564/JAMS.V2I1.161","DOIUrl":null,"url":null,"abstract":"High performance liquid chromatography (HPLC) was established to determine the concentration of Icariin II in rats. The time-dependent changes in rats after taking Icariin II were studied, and the main pharmacokinetic parameters were obtained. The main pharmacokinetic parameters of taking the medicine in a quiet state, taking the medicine after half an hour of exercise and taking the medicine after long-term exercise were compared to verify whether the absorption and utilization of the Icariin II were more favorable in the exercise state; The paper has important guiding significance for guiding athletes to safe medication and further development of this drug.","PeriodicalId":14958,"journal":{"name":"Journal of Advances in Medicine Science","volume":"263 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effects of Exercise on the Pharmacokinetics of Icariin II in Rats\",\"authors\":\"X. Kong\",\"doi\":\"10.30564/JAMS.V2I1.161\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"High performance liquid chromatography (HPLC) was established to determine the concentration of Icariin II in rats. The time-dependent changes in rats after taking Icariin II were studied, and the main pharmacokinetic parameters were obtained. The main pharmacokinetic parameters of taking the medicine in a quiet state, taking the medicine after half an hour of exercise and taking the medicine after long-term exercise were compared to verify whether the absorption and utilization of the Icariin II were more favorable in the exercise state; The paper has important guiding significance for guiding athletes to safe medication and further development of this drug.\",\"PeriodicalId\":14958,\"journal\":{\"name\":\"Journal of Advances in Medicine Science\",\"volume\":\"263 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-01-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Advances in Medicine Science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.30564/JAMS.V2I1.161\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Advances in Medicine Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30564/JAMS.V2I1.161","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effects of Exercise on the Pharmacokinetics of Icariin II in Rats
High performance liquid chromatography (HPLC) was established to determine the concentration of Icariin II in rats. The time-dependent changes in rats after taking Icariin II were studied, and the main pharmacokinetic parameters were obtained. The main pharmacokinetic parameters of taking the medicine in a quiet state, taking the medicine after half an hour of exercise and taking the medicine after long-term exercise were compared to verify whether the absorption and utilization of the Icariin II were more favorable in the exercise state; The paper has important guiding significance for guiding athletes to safe medication and further development of this drug.
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