Effects of Exercise on the Pharmacokinetics of Icariin II in Rats

Abstract

High performance liquid chromatography (HPLC) was established to determine the concentration of Icariin II in rats. The time-dependent changes in rats after taking Icariin II were studied, and the main pharmacokinetic parameters were obtained. The main pharmacokinetic parameters of taking the medicine in a quiet state, taking the medicine after half an hour of exercise and taking the medicine after long-term exercise were compared to verify whether the absorption and utilization of the Icariin II were more favorable in the exercise state; The paper has important guiding significance for guiding athletes to safe medication and further development of this drug.