Journal of Advances in Medicine Science最新文献

{"title":"Application Research of Clinical Nursing Teaching Model Based on PBL Mode","authors":"Fuan Wang","doi":"10.30564/jams.v2i4.1072","DOIUrl":"https://doi.org/10.30564/jams.v2i4.1072","url":null,"abstract":"Objective: To explore the application effect of PBL mode in clinical nursing teaching model. Methods: 40 nursing students who were internships from June 2017 to April 2018 in our hospital were selected as subjects. They were divided into two groups, the control group and the experimental group, with 20 in each group. The control group used the traditional teaching model, and the experimental group used the PBL teaching model to compare the clinical teaching effects of the two groups of nursing students. Results: There was no significant difference between the two groups of nursing students in the basic nursing knowledge, the professional practice operation under the simulated clinical operating environment and the basic nursing operation (P>0.05), in the clinical operation environment, the professional practice evaluation results of the experimental group were signifcantly better than those of the control group, and the difference was statistically signifcant (P<0.05). Conclusion: The PBL teaching model has a good teaching effect in clinical nursing teaching, which can effectively improve the professional practice level of nursing students in the clinical environment and meet the requirements of modern clinical nursing professional ability level, therefore, the PBL mode is worthy of popularization and application in clinical nursing teaching.","PeriodicalId":14958,"journal":{"name":"Journal of Advances in Medicine Science","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79509635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research on the Interventional Effects of Stress Psychological Nursing Method on Patients with Acute Coronary Syndrome","authors":"Zhuo Li, Guiying Yang, Jing Qian, Y. Xiang, Weishu Hu","doi":"10.30564/JAMS.V2I3.975","DOIUrl":"https://doi.org/10.30564/JAMS.V2I3.975","url":null,"abstract":"Objective: To investigate the interventional effects of stress psychological nursing method on patients with acute coronary syndrome (ACS). Methods: 100 patients with ACS who were rescued in the emergency department and department of cardiology of our hospital between January 2017 and December 2017 were enrolled. According to the random number method, the patients were divided into control group and observation group. There were 50 patients in each group. The interventions were given as routine nursing and stress psychological nursing, and the results of the two interventions were compared. Results: Before the intervention, there was no difference in the general clinical data between the control group and the observation group, which was not statistically signifcant; after the intervention for anxiety and depression, average hospitalization time, and off-bed time, the difference in data between the control group and the observation group on anxiety and depression was statistically signifcant. Moreover, the values of all the observation groups were lower than those of the control group. Conclusion: Applying stress psychological nursing method to the nursing of the patients with ACS can signifcantly improve their anxiety and depression, which signifcantly improves their quality of life, and enables the patients to better grasp the relevant health knowledge, at the same time, it obtains good intervention effects, which is worth promoting in a wider clinical scope.","PeriodicalId":14958,"journal":{"name":"Journal of Advances in Medicine Science","volume":"87 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84045827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Application of Realtime Fluorescence Quantitative PCR for Prenatal Screening of Group B Streptococcal Infections","authors":"Changzhi Xu, Donglin Zhu, Zhizhi Xie, Yun Xi","doi":"10.30564/JAMS.V2I3.669","DOIUrl":"https://doi.org/10.30564/JAMS.V2I3.669","url":null,"abstract":"Objective: In the prenatal screening, several different methods were used to detect the presence of group B streptococcus (GBS) infection, in this assay, the diagnostic value and clinical signifcance of the application of realtime fluorescent PCR were explored. Methods: A total of 86 women with 35-37 weeks pregnancy were enrolled, vaginal secretion samples were collected. Fluorescence PCR, bacterial culture and gene sequencing were used to detect whether there was GBS infection, and the results obtained were compared and analyzed. Results: 10 subjects were detected to be positive for GBS by fluorescence PCR (the positive rate was 11.6%), however, only 4 cases were positive for GBS by bacterial culture method (the positive rate was 4.7%). There was a statistically signifcant difference in the positive rate between the two methods (P<0.01). Compared with the results of gene sequencing, the detection of GBS infection by fluorescence PCR has an accuracy of 95.2%, and the sensitivity was 90.9% with 100% specificity. Conclusion: The application of realtime fluorescence quantitative PCR for the detection of GBS infection is signifcantly better than the use of bacterial culture method. Compared with the gold standard method (gene sequencing method), its detection effciency, accuracy, sensitivity and specifcity are relatively high. In summary, PCR for prenatal screening of GBS is worthy of promotion in clinical practice.","PeriodicalId":14958,"journal":{"name":"Journal of Advances in Medicine Science","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75439898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison and correlation study of polar biomarkers of CKD patients in saliva and serum by UPLC-ESI-MS","authors":"Jielian Yan, Li Zhou, Xiao-Yun Tang, Yong Liu, Y. Duan","doi":"10.30564/JAMS.V2I3.640","DOIUrl":"https://doi.org/10.30564/JAMS.V2I3.640","url":null,"abstract":"Abstract:There are abundant reports on the use of aromatic amino acids and creatinineas biomarkers in serum and urine forCKD(chronic kidney disease). However, investigationsinto these bio-species in bio-fluids, such as saliva and sweat, are rarely reported. Increasing interest in non-invasive methods for medical diagnosis advocates for the testing of these bio-fluidstoidentify potential biomarkers for prompt clinical andpreliminary screening using advanced analytical equipment.Unstimulated whole saliva samples were obtained from twenty-seven CKD patients and an equivalent number of healthy individuals. Saliva was assayed with ultra-performance liquid chromatography coupled with electro-spray ionization tandem mass spectrometry (UPLC-ESI-MS) in hydrophilic interaction chromatography mode. The data were analyzed using a student’s t test and receiver operatingcharacteristic(ROC) to evaluate the predictive power of several potential biomarkers (P<0.01) in saliva for preliminary CKD screening. Through testing of salivary samples between CKD patients and healthy individuals, we found three possible salivary biomarkers that demonstrated significant differences(P<0.01) from the nine reported species in serum and/or urine. The area under the curve (AUC) values for control vs CKDpatientsfor on L-phenylalanine, L- tryptophan, and creatinine were 0.863, 0.834, and 0.916, respectively. This is the first report to compare serum and urine biomarkers in saliva between CKD patients and healthy people. This study explores the potential of CKD diagnosis by saliva, and demonstrates a positive correlation between salivary and serum creatinine.","PeriodicalId":14958,"journal":{"name":"Journal of Advances in Medicine Science","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81048692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NAT2 Involed in the Susceptibility to Antituberculosis Drug-Induced Liver Injury","authors":"Donglin Zhu, Changzhi Xu, Zhizhi Xie, G. Xiao, Yun Xi","doi":"10.30564/JAMS.V2I3.754","DOIUrl":"https://doi.org/10.30564/JAMS.V2I3.754","url":null,"abstract":"Objective: To investigate whether the N-acetyltransferase 2 (NAT2) gene is involved in the development of susceptibility to antituberculosis drug-induced liver damage (ATDLI) in patients with pulmonary tuberculosis in the Han nationality. Methods: We retrospectively analyzed 300 cases of tuberculosis patients without liver damage (control group) and 221 cases of tuberculosis patients with liver damage after antituberculosis treatment (case group). After antituberculosis treatment, genetic polymorphisms of NAT2 were analyzed in those patients using MassARRAY method. Results: Of the 10 tagged SNPs selected, In the promoter area of NAT2, the frequencies of T allele in rs4646243 and A allele in rs4646246 were signifcantly higher in the patients with ATDLI than controls (0.569 vs. 0.483, p=0.0062 and 0.567 vs 0.487, p=0.0103). The A allele of rs1115784 in the intron area showed a significant association with the development of ATDLI (0.389 vs 0.305, p = 0.0043). The frequencies of the mutated genes T and A in rs1041983 and rs1799930 in the second exon region were significantly higher than those in the control group (0.491 vs 0.360, p<0.00001 and 0.336 vs 0.212, respectively; p<0.00001). Two monomer domains were found in the 10 tag SNP sites, haplotype ht [TGAA] in monomeric domain 1 and haplotype ht [TAG] in monomeric domain 2, both were signifcantly more likely to be detected in the liver injury group than in the control group(p=0.0038, p<0.001, respectively). Two haplotypes were also found on the NAT2 gene: haplotype ht [CGGG] in monomeric domain 1 and ht [CGG] in block 2, and their presence means a lower risk of liver damage. Conclusion: NAT2 genotypes might have signifcant association with the risk of ATDLI in the Chinese Han nationality. By detecting the NAT2 gene and its haplotype, we can screen patients with a higher risk of liver damage before anti-TB treatment and take measures for the protection of patients.","PeriodicalId":14958,"journal":{"name":"Journal of Advances in Medicine Science","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82606038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Warm Acupuncture on “Dinghui Acupoint” and “Heart Acupoint” in Traditional Mongolian Medicine on Behaviors and Hypothalamic Inammatory Cytokines in Rats with Chronic Fatigue Syndrome","authors":"Shu-Mei Bai, Ling Shui, Qin-Ba-Te-Er Si, Ying-song Chen","doi":"10.30564/JAMS.V2I2.456","DOIUrl":"https://doi.org/10.30564/JAMS.V2I2.456","url":null,"abstract":"Objective: To observe the effects of warm acupuncture on “Dinghui Acupoint” and “Heart Acupoint” in Traditional Mongolian Medicine on behavior and hypothalamic inflammatory cytokines IL-1β, IL-6 and IFN-r in Rats with Chronic Fatigue Syndrome. Methods: SD rats were randomly divided into normal group, model group, warm acupuncture group and moxibustion positive control group. The latter three groups of rats were used to establish a model of rats with chronic fatigue syndrome (CFS) using a combination of physical fatigue and mental fatigue. When establishing the model of warm acupuncture group, “Dinghui Acupoint” and “Heart Acupoint” intervention was carried out; when establishing the model of moxibustion positive control group, “Zusanli Acupoint” intervention was carried out on both sides. Behavioral observations (body weight, exhaustive swimming time, tail suspension experiment, water maze) were performed before and after modeling. The hypothalamic inflammatory cytokines IL-1β, IL-6 and IFN-r were detected by ELISA method after warm acupuncture and moxibustion intervention. Results: After 21 days of modeling, the body weight of the rats in each group was significantly lower than that in the normal group, and there was a significant difference (P<0.01); Compared with the model group, the weight of the rats in the warm acupuncture group increased significantly, and there was a significant difference (P<0.01); Compared with the model group, the exhaustive swimming time of the rats in the warm acupuncture group was significantly prolonged, and there was a significant difference (P<0.01); Compared with the moxibustion group, the exhaustion time of the rats in the warm acupuncture group was relatively prolonged, and there was a significant difference (P<0.05); Compared with the normal group, the tail suspension time of the model group was significantly prolonged, and there was a significant difference (P<0.05); Compared with the model group, there was a significant difference in the duration of the suspension of the warm acupuncture group and the moxibustion group (P<0.01); Compared with the normal group, the total distance of the water maze test was shorter in the model group, and there was a significant difference (P<0.01); Compared with the model group, both the warm acupuncture group and the moxibustion group were prolonged, and there was a significant difference (P<0.05); Compared with the moxibustion group, the distance between the rats in the warm acupuncture group was relatively longer, but there was no significant difference (P>0.05); Compared with the normal group, IL-1β, IL-6 and IFN-r increased significantly in the model group and there was a significant difference (P<0.05); Compared with the model group, IL-1β and IL-6 in the warm acupuncture group was significantly decreased (P<0.05), and the IL-6 in the moxibustion group was significantly different (P<0.05); Compared with the model group, there was no significant difference between the I","PeriodicalId":14958,"journal":{"name":"Journal of Advances in Medicine Science","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75401505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IVF Development and Analysis of Neonatal Conditions","authors":"Tian Tian, Weixin Huang","doi":"10.30564/JAMS.V2I2.509","DOIUrl":"https://doi.org/10.30564/JAMS.V2I2.509","url":null,"abstract":"This paper rst discusses the developmental origin of IVF (In vitro fertilization) and analyzes the four generations of IVF technology in detail.Then, combined with its own work experience, it discusses the neonatalsituation of IVF, in order to improve reference for other medical staff.","PeriodicalId":14958,"journal":{"name":"Journal of Advances in Medicine Science","volume":"107 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80789082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Teaching Research and Reform of Higher Vocational Medical Education in Guizhou Province of China","authors":"Wang Ding, Jicheng Lin, Jianhui Yang, Xianming Cao, Fang Cao, Shaomei Lu","doi":"10.30564/JAMS.V2I2.386","DOIUrl":"https://doi.org/10.30564/JAMS.V2I2.386","url":null,"abstract":"With the development of Guizhou’s economy and society, higher vocational medical education in Guizhou has developed rapidly, making it itsmission to cultivate practical and skilled talents oriented to the grassrootsand serving for frontline. However, due to the social environment, policyenvironment and insufficient funding, many difficulties and problemsare faced. It is necessary to have a unied management throughout theprovince, rationally lay out higher vocational colleges and specialties,and promote the healthy and rapid development of medical higher vocational education in Guizhou with advanced concepts, proper policies, andsufcient funds in place, making higher vocational medical education inGuizhou enter a benign development period","PeriodicalId":14958,"journal":{"name":"Journal of Advances in Medicine Science","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81651514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Application of Theoretical Models in the Studies of Physical Activity Behaviors of the Elderly in China","authors":"Yuquan Chen, Yuqi Wang, F. Meng, Zifei Du, Qun Zuo","doi":"10.30564/JAMS.V2I2.547","DOIUrl":"https://doi.org/10.30564/JAMS.V2I2.547","url":null,"abstract":"By using the method of literature review, this paper introduces the popular theoretical models which have shown to better explain physical activity behaviors at a certain degree, summarizes the dominating theoretical models in the studies of physical activity behaviors of the elderly in China. In addition, shortcomings and future prospects are pointed out at the end.","PeriodicalId":14958,"journal":{"name":"Journal of Advances in Medicine Science","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82140625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of Seamless Nursing Management in Emergency-ICU Patient Safety Transfer and Handover","authors":"Qian Wang, Lili Wei","doi":"10.30564/JAMS.V2I2.514","DOIUrl":"https://doi.org/10.30564/JAMS.V2I2.514","url":null,"abstract":"Objective: To analyze the application effect of seamless nursing management in the safe transfer and handover of emergency-ICU patients. Methods: A total of 160 patients admitted to the emergency department-ICU from November 2017 to July 2018 were randomly divided into the control group and the observation group, with 80 patients in each group. Among them, the patients in the control group underwent routine nursing management mode, and the patients in the observation group were treated with seamless nursing, comparing the transfer of the two groups of patients and the satisfaction score of the emergency-ICU nursing staff. Results: The transfer status of the observation group and the satisfaction score of the emergency-ICU nursing staff were significantly better than those of the control group. Conclusion: Seamless nursing management can improve the overall efficiency of transfer.","PeriodicalId":14958,"journal":{"name":"Journal of Advances in Medicine Science","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86223365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}