Journal Francais D Ophtalmologie最新文献

{"title":"Honeycomb appearance of emulsified silicone oil.","authors":"K Tripathy, A Bose, S Datta","doi":"10.1016/j.jfo.2025.104541","DOIUrl":"https://doi.org/10.1016/j.jfo.2025.104541","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148828892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of botulinum toxin on tear film and corneal epithelial remodeling in patients with essential blepharospasm","authors":"B. Kesimal, S.İ. Kocamış, A.Ş. Doğan","doi":"10.1016/j.jfo.2026.104911","DOIUrl":"10.1016/j.jfo.2026.104911","url":null,"abstract":"<div><h3>Purpose</h3><div>Benign essential blepharospasm (BEB) is a focal dystonia characterized by involuntary eyelid contractions that can disrupt tear film stability and corneal morphology. Botulinum toxin type A (BTX-A) injection is the standard treatment, yet its impact on ocular surface health and corneal epithelial structure remains unclear. This study aimed to assess the effects of periocular BTX-A on tear film parameters and corneal epithelial remodeling using anterior segment optical coherence tomography (AS-OCT).</div></div><div><h3>Methods</h3><div>This retrospective, single-center study included 35 eyes of 35 BEB patients treated with standardized periocular BTX-A injection (total dose ∼12.5 units). Ocular surface parameters Ocular Surface Disease Index (OSDI), tear breakup time (TBUT), Schirmer test, tear meniscus height (TMH), and meibomian gland dropout were evaluated at baseline and 3 months post-treatment. Corneal epithelial maps obtained via AS-OCT provided central, superior, and inferior epithelial thicknesses and irregularity indices. Corneal power and astigmatism were analyzed by topography. Pre- and post-treatment values were compared using paired tests.</div></div><div><h3>Results</h3><div>At 3 months, blepharospasm severity and OSDI scores improved significantly (<em>P</em> <!--><<!--> <!-->0.001). TBUT and TMH increased (<em>P</em> <!--><<!--> <!-->0.001), while Schirmer test and gland dropout were unchanged. Superior epithelial thickness increased and irregularity indices decreased (<em>P</em> <!--><<!--> <!-->0.001), indicating smoother remodeling. Corneal power and astigmatism decreased significantly (<em>P</em> <!--><<!--> <!-->0.001), consistent with corneal flattening. No adverse effects were observed. Improvements correlated with reduced spasm severity.</div></div><div><h3>Conclusion</h3><div>BTX-A injection in BEB patients alleviates spasms and enhances tear film stability and epithelial regularity. The treatment is safe and well tolerated, offering additional ocular surface benefits beyond motor symptom control.</div></div><div><h3>Objectif</h3><div>Le blépharospasme essentiel bénin (BEB) est une dystonie focale caractérisée par des contractions involontaires des paupières, susceptibles d’altérer la stabilité du film lacrymal et la morphologie cornéenne. L’injection de toxine botulinique de type A (BTX-A) constitue le traitement de référence; toutefois, son impact sur la surface oculaire et la structure de l’épithélium cornéen demeure insuffisamment élucidé. Cette étude visait à évaluer les effets de la BTX-A périoculaire sur les paramètres du film lacrymal et le remodelage de l’épithélium cornéen à l’aide de la tomographie par cohérence optique du segment antérieur (AS-OCT).</div></div><div><h3>Méthodes</h3><div>Cette étude rétrospective monocentrique a inclus 35 yeux de 35 patients atteints de BEB traités par injection périoculaire standardisée de BTX-A (dose totale approximative de 12,5 unités). L","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"49 6","pages":"Article 104911"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148015653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The uninvited guest: Retained intrasaccal bony fragments complicating an otherwise uneventful endonasal DCR","authors":"T. Messiant , S. Baillif , A. Mathieu , Q. Lamy , P. Denis , A. Martel","doi":"10.1016/j.jfo.2026.104919","DOIUrl":"10.1016/j.jfo.2026.104919","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"49 6","pages":"Article 104919"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148149871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The point of no return: Refractory globe luxation rescued by deep orbital decompression","authors":"T. Messiant , S. Baillif , E. Pelletier-Goulet , Q. Lamy , A. Mathieu , P. Denis , A. Martel","doi":"10.1016/j.jfo.2026.104913","DOIUrl":"10.1016/j.jfo.2026.104913","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"49 6","pages":"Article 104913"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148015667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seizure-induced globe subluxation","authors":"E. Lange , O. Morel , M. Beaufigeau , T. Messiant , A. Gleizal , J. Chauvel-Picard , S. Morand","doi":"10.1016/j.jfo.2026.104915","DOIUrl":"10.1016/j.jfo.2026.104915","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"49 6","pages":"Article 104915"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148149901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TNF-α blockers and demyelinating lesions in pediatric non-infectious uveitis: Insights from a real world cohort","authors":"P. Isik Eker , E. Esen , G.G. Mert , Ö. Kaya , R.M.K. Ekinci , N. Demircan","doi":"10.1016/j.jfo.2026.104914","DOIUrl":"10.1016/j.jfo.2026.104914","url":null,"abstract":"<div><h3>Purpose</h3><div>To characterize childhood non-infectious uveitis (NIU) patients who developed demyelinating lesions during TNF-α blocker therapy and to investigate potential risk factors associated with this pathology.</div></div><div><h3>Methods</h3><div>This retrospective single-center cohort study included pediatric NIU patients treated with TNF-α blockers who had undergone brain magnetic resonance imaging (MRI) at any time during the course of the disease. Demographic and clinical characteristics, the ocular complication score (OCS), and imaging data were reviewed.</div></div><div><h3>Results</h3><div>The study cohort included 45 patients with a mean age of 13.8<!--> <!-->±<!--> <!-->4.46 (5–22) years. The mean duration of TNF-α blocker treatment within the study period was 44<!--> <!-->±<!--> <!-->27.9 months. The OCS did not significantly change from baseline to final visit (<em>P</em> <!-->=<!--> <!-->0.10). Brain MRI was performed before initiation of TNF-α blocker therapy in 21 (46.6%) patients and during treatment in 24 (53.4%). All demyelinating lesions were detected on MRIs obtained after TNF-α blocker initiation (median: 52 months; range 18–84). Central nervous system (CNS) demyelinating lesions were identified in 4 (8.8%) patients; two were diagnosed with multiple sclerosis, and two with radiologically isolated syndrome.</div></div><div><h3>Conclusion</h3><div>CNS demyelination was uncommon but clinically relevant in pediatric NIU patients receiving TNF-α blockers. Demyelinating lesions may be associated with pars planitis, neurologic symptoms, and/or a family history of demyelinating disease. During treatment, CNS MRI may be considered when new neurologic symptoms accompany an uncontrolled uveitis flare, particularly in the presence of newly developed ocular inflammatory findings.</div></div><div><h3>Objectif</h3><div>Caractériser les patients pédiatriques atteints d’uvéite non infectieuse (UNI) ayant développé des lésions démyélinisantes au cours d’un traitement par inhibiteurs du TNF-α et étudier les facteurs de risque potentiellement associés à cette pathologie.</div></div><div><h3>Méthodes</h3><div>Cette étude de cohorte rétrospective monocentrique a inclus des patients pédiatriques atteints d’UNI traités par inhibiteurs du TNF-α et ayant bénéficié d’une imagerie par résonance magnétique (IRM) cérébrale à n’importe quel moment de l’évolution de la maladie. Les caractéristiques démographiques et cliniques, le score de complications oculaires (OCS) et les données d’imagerie ont été analysés.</div></div><div><h3>Résultats</h3><div>La cohorte comprenait 45 patients, d’âge moyen 13,8<!--> <!-->±<!--> <!-->4,46 ans (5–22). La durée moyenne d’exposition aux inhibiteurs du TNF-α pendant la période d’étude était de 44<!--> <!-->±<!--> <!-->27,9 mois. L’OCS n’a pas significativement varié entre l’inclusion et la dernière visite (<em>p</em> <!-->=<!--> <!-->0,10). L’IRM cérébrale a été réalisée avant l’initiation du traitement p","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"49 6","pages":"Article 104914"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148042587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intérêt des potentiels évoqués visuels pour le diagnostic de la neuropathie optique toxico-carentielle","authors":"J. Blin , C. Marks , I. Bouacha , J.P. Woillez , S. Defoort , V. Smirnov","doi":"10.1016/j.jfo.2026.104917","DOIUrl":"10.1016/j.jfo.2026.104917","url":null,"abstract":"<div><h3>Contexte</h3><div>La neuropathie optique toxico-carentielle (NOCT) est un diagnostic d’élimination reposant sur l’interrogatoire et un faisceau d’arguments. En cas d’interrogatoire non contributif ou de présentation atypique, le diagnostic formel peut parfois être difficile et retarder la prise en charge. L’objectif de cette étude était d’évaluer la valeur diagnostique des potentiels évoqués visuels (PEV) damiers pour la NOCT. L’hypothèse de départ était que les PEV dans la NOCT sont plus altérés que ne le suppose la meilleure acuité visuelle corrigée (MAVC) : nous avons considéré que pour les MAVC ≥ 1/20<sup>e</sup> et MAVC ≥ 2/10<sup>e</sup>, la réponse aux damiers de 60’ et 15’ respectivement était attendue.</div></div><div><h3>Méthodes</h3><div>Étude observationnelle, monocentrique et rétrospective. Ont été recueillies les données démographiques, les données déclarées de consommation alcoolo-tabagique, les données de l’examen ophtalmologique, et notamment la MAVC ainsi que les PEV 60’ et 15’ au diagnostic. Nous avons créé deux groupes d’acuité visuelle : l’un avec MAVC ≥ 1/20<sup>e</sup> pour lequel nous avons décrit les résultats de PEV 60’, et l’autre avec MAVC ≥ 2/10<sup>e</sup> pour lequel nous avons décrit les résultats de PEV 15’.</div></div><div><h3>Résultats</h3><div>Soixante-cinq patients ont été inclus. Alors que la MAVC était ≥ 1/20<sup>e</sup>, 64,2 % des PEV 60’ étaient indiscernables du bruit de fond. De même, 95,3 % des PEV 15’ n’étaient pas discernables pour une MAVC ≥ 2/10<sup>e</sup>.</div></div><div><h3>Conclusion</h3><div>Les résultats de notre étude indiquent que dans la NOCT les PEV sont plus altérés que ne le veut l’acuité visuelle. Il peut s’agir d’un élément diagnostique en faveur d’une NOCT.</div></div><div><h3>Background</h3><div>Toxic/nutritional optic neuropathy (TON) is a diagnosis of exclusion after an extensive work-up. In cases of a non-contributory history or atypical presentation, formal diagnosis can sometimes be difficult and delay management. The goal of this study was to evaluate the diagnostic value of checkerboard visual evoked potentials (VEP) for toxic/nutritional optic neuropathy. The working hypothesis was that, in TON, VEPs are more affected than best corrected visual acuity (BCVA). We assumed that, for BCVA ≥ 1/20 and ≥ 2/10, the 60’ and 15’ checkerboard VEP responses would be respectively affected.</div></div><div><h3>Methods</h3><div>This was an observational, single-center, retrospective study. We collected demographic data, self-declared data on alcohol and tobacco use, data from the ophthalmologic examination, and notably the BCVA as well as the 60’ and 15’ VEPs. We divided the subjects into two visual acuity groups, one with BCVA ≥ 1/20, for which we reported the 60’ VEP results, and the other with BCVA ≥ 2/10, for which we reported the 15’ VEP results.</div></div><div><h3>Results</h3><div>Sixty-five patients were included. For those with BCVA ≥ 1/20, 64.2% of the 60’ VEPs were und","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"49 6","pages":"Article 104917"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148149932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Full thickness macular hole secondary to valsalva retinopathy with spontaneous closure","authors":"M. Calatayud-Riera, Y. Bertolani, F.J. Valentín-Bravo, A. Goñi-Guarro, L. Broc-Iturralde","doi":"10.1016/j.jfo.2026.104910","DOIUrl":"10.1016/j.jfo.2026.104910","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"49 6","pages":"Article 104910"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148015613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Secondary loss of endothelial regeneration after ripasudil associated with delayed allergic contact dermatitis","authors":"J. Pérez-Esquiva , S. Taña-Sanz , J. Lamarca","doi":"10.1016/j.jfo.2026.104918","DOIUrl":"10.1016/j.jfo.2026.104918","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"49 6","pages":"Article 104918"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148143494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dacryocystorhinostomie externe et endonasale : comparaison de l’impact fonctionnel et de la qualité de vie rapportés par les patients","authors":"T.-M. Galuscan , P.-A. Marty , P. Saguet , V. Patron , J.-C. Quintyn","doi":"10.1016/j.jfo.2026.104902","DOIUrl":"10.1016/j.jfo.2026.104902","url":null,"abstract":"<div><h3>Introduction</h3><div>L’objectif de cette étude est de comparer les résultats fonctionnels et l’impact sur la qualité de vie des dacryocystorhinostomies externes et endonasales, à l’aide du questionnaire Lac-Q.</div></div><div><h3>Matériel et méthodes</h3><div>Il s’agit d’une étude observationnelle, rétrospective et comparative menée au CHU de Caen entre janvier 2019 et décembre 2022. Les patients opérés de DCR externe ou endonasale ont été évalués à l’aide du questionnaire Lac-Q, traduit en français, complété entre février 2024 et février 2025. Les données recueillies incluaient les scores pré- et postopératoires d’impact fonctionnel, social, la satisfaction globale et la gêne esthétique.</div></div><div><h3>Résultats</h3><div>Au total, 39 patients ont été inclus (29 voies externes, 10 voies endonasales). En postopératoire, une amélioration significative du score total, du score fonctionnel et du score d’impact social est observée dans les deux groupes (<em>p</em> <!--><<!--> <!-->0,001). Les taux de satisfaction étaient élevés et la gêne esthétique faible. Aucune différence statistiquement significative n’a été retrouvée entre les deux techniques sur l’amélioration du score (<em>p</em> <!-->=<!--> <!-->0,175).</div></div><div><h3>Conclusion</h3><div>Les DCR externe et endonasale améliorent significativement les symptômes et la qualité de vie des patients sans différence entre les deux techniques. L’évaluation par le Lac-Q permet de quantifier ce bénéfice fonctionnel et social, complétant les critères anatomiques classiques. Les deux approches présentent des résultats comparables, laissant le choix de la technique au contexte clinique et aux préférences du chirurgien et du patient.</div></div><div><h3>Introduction</h3><div>The goal of this study is to compare the functional outcomes and impact on quality of life of external and endonasal dacryocystorhinostomies using the Lac-Q questionnaire.</div></div><div><h3>Material and methods</h3><div>This was an observational, retrospective, and comparative study conducted at Caen University Hospital between January 2019 and December 2022. Patients who underwent external or endonasal DCR were evaluated using the French translation of the Lac-Q questionnaire, completed between February 2024 and February 2025. Collected data included pre- and postoperative scores for functional and social impact, overall satisfaction, and cosmetic discomfort.</div></div><div><h3>Results</h3><div>Thirty-nine patients were included (29 external, 10 endonasal). Postoperatively, a significant improvement in total score, functional score, and social impact score was observed in both groups (<em>P</em> <!--><<!--> <!-->0.001). Satisfaction rates were high, and cosmetic concerns were minimal. No statistically significant difference was found between the techniques in terms of score improvement (<em>P</em> <!-->=<!--> <!-->0.175).</div></div><div><h3>Conclusion</h3><div>Both external and endonasal DCR significantly i","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"49 6","pages":"Article 104902"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148015587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}