{"title":"Qui de nous deux…attire l’autre ?","authors":"A. Barbé","doi":"10.1016/j.jfo.2026.104997","DOIUrl":"10.1016/j.jfo.2026.104997","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"49 8","pages":"Article 104997"},"PeriodicalIF":1.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149166889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C Baqadir, K Boukili, M El Alami, M Issa Mahamat, G Daghouj, L El Maaloum, B Allali, A El Kettani
{"title":"[Malignant medulloepithelioma of the optic nerve with intracranial extension].","authors":"C Baqadir, K Boukili, M El Alami, M Issa Mahamat, G Daghouj, L El Maaloum, B Allali, A El Kettani","doi":"10.1016/j.jfo.2025.104456","DOIUrl":"https://doi.org/10.1016/j.jfo.2025.104456","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148968724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Look deeper: A rare presentation of peripapillary staphyloma.","authors":"A Dey Sarkar, H Parida, N Babu Kannan","doi":"10.1016/j.jfo.2025.104459","DOIUrl":"https://doi.org/10.1016/j.jfo.2025.104459","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148944826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Honeycomb appearance of emulsified silicone oil.","authors":"K Tripathy, A Bose, S Datta","doi":"10.1016/j.jfo.2025.104541","DOIUrl":"https://doi.org/10.1016/j.jfo.2025.104541","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148828892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of botulinum toxin on tear film and corneal epithelial remodeling in patients with essential blepharospasm","authors":"B. Kesimal, S.İ. Kocamış, A.Ş. Doğan","doi":"10.1016/j.jfo.2026.104911","DOIUrl":"10.1016/j.jfo.2026.104911","url":null,"abstract":"<div><h3>Purpose</h3><div>Benign essential blepharospasm (BEB) is a focal dystonia characterized by involuntary eyelid contractions that can disrupt tear film stability and corneal morphology. Botulinum toxin type A (BTX-A) injection is the standard treatment, yet its impact on ocular surface health and corneal epithelial structure remains unclear. This study aimed to assess the effects of periocular BTX-A on tear film parameters and corneal epithelial remodeling using anterior segment optical coherence tomography (AS-OCT).</div></div><div><h3>Methods</h3><div>This retrospective, single-center study included 35 eyes of 35 BEB patients treated with standardized periocular BTX-A injection (total dose ∼12.5 units). Ocular surface parameters Ocular Surface Disease Index (OSDI), tear breakup time (TBUT), Schirmer test, tear meniscus height (TMH), and meibomian gland dropout were evaluated at baseline and 3 months post-treatment. Corneal epithelial maps obtained via AS-OCT provided central, superior, and inferior epithelial thicknesses and irregularity indices. Corneal power and astigmatism were analyzed by topography. Pre- and post-treatment values were compared using paired tests.</div></div><div><h3>Results</h3><div>At 3 months, blepharospasm severity and OSDI scores improved significantly (<em>P</em> <!--><<!--> <!-->0.001). TBUT and TMH increased (<em>P</em> <!--><<!--> <!-->0.001), while Schirmer test and gland dropout were unchanged. Superior epithelial thickness increased and irregularity indices decreased (<em>P</em> <!--><<!--> <!-->0.001), indicating smoother remodeling. Corneal power and astigmatism decreased significantly (<em>P</em> <!--><<!--> <!-->0.001), consistent with corneal flattening. No adverse effects were observed. Improvements correlated with reduced spasm severity.</div></div><div><h3>Conclusion</h3><div>BTX-A injection in BEB patients alleviates spasms and enhances tear film stability and epithelial regularity. The treatment is safe and well tolerated, offering additional ocular surface benefits beyond motor symptom control.</div></div><div><h3>Objectif</h3><div>Le blépharospasme essentiel bénin (BEB) est une dystonie focale caractérisée par des contractions involontaires des paupières, susceptibles d’altérer la stabilité du film lacrymal et la morphologie cornéenne. L’injection de toxine botulinique de type A (BTX-A) constitue le traitement de référence; toutefois, son impact sur la surface oculaire et la structure de l’épithélium cornéen demeure insuffisamment élucidé. Cette étude visait à évaluer les effets de la BTX-A périoculaire sur les paramètres du film lacrymal et le remodelage de l’épithélium cornéen à l’aide de la tomographie par cohérence optique du segment antérieur (AS-OCT).</div></div><div><h3>Méthodes</h3><div>Cette étude rétrospective monocentrique a inclus 35 yeux de 35 patients atteints de BEB traités par injection périoculaire standardisée de BTX-A (dose totale approximative de 12,5 unités). L","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"49 6","pages":"Article 104911"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148015653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Messiant , S. Baillif , E. Pelletier-Goulet , Q. Lamy , A. Mathieu , P. Denis , A. Martel
{"title":"The point of no return: Refractory globe luxation rescued by deep orbital decompression","authors":"T. Messiant , S. Baillif , E. Pelletier-Goulet , Q. Lamy , A. Mathieu , P. Denis , A. Martel","doi":"10.1016/j.jfo.2026.104913","DOIUrl":"10.1016/j.jfo.2026.104913","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"49 6","pages":"Article 104913"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148015667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Isik Eker , E. Esen , G.G. Mert , Ö. Kaya , R.M.K. Ekinci , N. Demircan
{"title":"TNF-α blockers and demyelinating lesions in pediatric non-infectious uveitis: Insights from a real world cohort","authors":"P. Isik Eker , E. Esen , G.G. Mert , Ö. Kaya , R.M.K. Ekinci , N. Demircan","doi":"10.1016/j.jfo.2026.104914","DOIUrl":"10.1016/j.jfo.2026.104914","url":null,"abstract":"<div><h3>Purpose</h3><div>To characterize childhood non-infectious uveitis (NIU) patients who developed demyelinating lesions during TNF-α blocker therapy and to investigate potential risk factors associated with this pathology.</div></div><div><h3>Methods</h3><div>This retrospective single-center cohort study included pediatric NIU patients treated with TNF-α blockers who had undergone brain magnetic resonance imaging (MRI) at any time during the course of the disease. Demographic and clinical characteristics, the ocular complication score (OCS), and imaging data were reviewed.</div></div><div><h3>Results</h3><div>The study cohort included 45 patients with a mean age of 13.8<!--> <!-->±<!--> <!-->4.46 (5–22) years. The mean duration of TNF-α blocker treatment within the study period was 44<!--> <!-->±<!--> <!-->27.9 months. The OCS did not significantly change from baseline to final visit (<em>P</em> <!-->=<!--> <!-->0.10). Brain MRI was performed before initiation of TNF-α blocker therapy in 21 (46.6%) patients and during treatment in 24 (53.4%). All demyelinating lesions were detected on MRIs obtained after TNF-α blocker initiation (median: 52 months; range 18–84). Central nervous system (CNS) demyelinating lesions were identified in 4 (8.8%) patients; two were diagnosed with multiple sclerosis, and two with radiologically isolated syndrome.</div></div><div><h3>Conclusion</h3><div>CNS demyelination was uncommon but clinically relevant in pediatric NIU patients receiving TNF-α blockers. Demyelinating lesions may be associated with pars planitis, neurologic symptoms, and/or a family history of demyelinating disease. During treatment, CNS MRI may be considered when new neurologic symptoms accompany an uncontrolled uveitis flare, particularly in the presence of newly developed ocular inflammatory findings.</div></div><div><h3>Objectif</h3><div>Caractériser les patients pédiatriques atteints d’uvéite non infectieuse (UNI) ayant développé des lésions démyélinisantes au cours d’un traitement par inhibiteurs du TNF-α et étudier les facteurs de risque potentiellement associés à cette pathologie.</div></div><div><h3>Méthodes</h3><div>Cette étude de cohorte rétrospective monocentrique a inclus des patients pédiatriques atteints d’UNI traités par inhibiteurs du TNF-α et ayant bénéficié d’une imagerie par résonance magnétique (IRM) cérébrale à n’importe quel moment de l’évolution de la maladie. Les caractéristiques démographiques et cliniques, le score de complications oculaires (OCS) et les données d’imagerie ont été analysés.</div></div><div><h3>Résultats</h3><div>La cohorte comprenait 45 patients, d’âge moyen 13,8<!--> <!-->±<!--> <!-->4,46 ans (5–22). La durée moyenne d’exposition aux inhibiteurs du TNF-α pendant la période d’étude était de 44<!--> <!-->±<!--> <!-->27,9 mois. L’OCS n’a pas significativement varié entre l’inclusion et la dernière visite (<em>p</em> <!-->=<!--> <!-->0,10). L’IRM cérébrale a été réalisée avant l’initiation du traitement p","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"49 6","pages":"Article 104914"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148042587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}