E. Blavakis , S. Magnin , H. Massa , G. Thumann , M. Kecik
{"title":"The watchmaker's eye: Exposure keratopathy with secondary limbal stem cell deficiency due to the use of a loupe","authors":"E. Blavakis , S. Magnin , H. Massa , G. Thumann , M. Kecik","doi":"10.1016/j.jfo.2025.104444","DOIUrl":"10.1016/j.jfo.2025.104444","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"48 4","pages":"Article 104444"},"PeriodicalIF":1.2,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143387609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Blumen , A. Denoyer , A. Grise-Dulac , A. Rousseau , C. Schweitzer , P. Rozot , F. Aptel
{"title":"Utilisation des implants premium chez les patients glaucomateux : conseils de la Société française du glaucome (SFG) et de la Société de l’association française des implants intra-oculaires et de chirurgie réfractive (SAFIR)","authors":"E. Blumen , A. Denoyer , A. Grise-Dulac , A. Rousseau , C. Schweitzer , P. Rozot , F. Aptel","doi":"10.1016/j.jfo.2025.104431","DOIUrl":"10.1016/j.jfo.2025.104431","url":null,"abstract":"<div><div>Les progrès récents des techniques chirurgicales et des implants ont transformé la chirurgie de la cataracte en véritable chirurgie réfractive, permettant à de nombreux patients de se passer de correction optique. Les implants « premium » offrent de multiples options pour corriger les amétropies – y compris l’astigmatisme – et les effets de la presbytie. Bien que la chirurgie de la cataracte soit souvent bénéfique chez les patients glaucomateux, la neuropathie optique glaucomateuse peut altérer la qualité de la vision et affecter les résultats des implants premium, en particulier des implants multifocaux. Cette revue concise propose des recommandations pratiques sur l’utilisation des implants premium en fonction du type, du stade et de l’évolutivité du glaucome, en se basant sur les données scientifiques actuelles. Les implants toriques monofocaux sont envisageables pour corriger l’astigmatisme chez les patients glaucomateux, mais nécessitent une évaluation clinique minutieuse. Les implants « monofocaux plus » et certains implants à profondeur de champ étendue (EDOF) peuvent également être envisagés, avec des précautions spécifiques. Les implants multifocaux diffractifs et réfractifs ne sont pas conseillés en cas de glaucome ou en cas d’hypertonie oculaire avec des facteurs de risque d’évolution vers un glaucome. En conclusion, les indications des implants premium chez les patients glaucomateux doivent faire l’objet d’une sélection rigoureuse et individualisée, et d’explications exhaustives.</div></div><div><div>Recent advances in surgical techniques and intraocular lens implants have transformed cataract surgery into a true refractive procedure, enabling many patients to forgo optical correction. “Premium” IOL's offer multiple options for correcting refractive errors, including astigmatism, and addressing the effects of presbyopia. While cataract surgery is often beneficial for glaucoma patients, glaucomatous optic neuropathy can impair visual quality and impact the outcomes of premium IOL's, particularly multifocal IOL's. This concise review provides practical recommendations for the use of premium IOL's based on the type, stage and progression profile of glaucoma, supported by current scientific data. Monofocal toric IOL's may be considered to correct astigmatism in glaucoma patients but require careful clinical evaluation. “Monofocal plus” IOL's and certain extended depth of focus (EDOF) IOL's may also be viable options, provided that specific precautions are taken. However, diffractive and refractive multifocal IOL's are not recommended for patients with glaucoma or ocular hypertension with risk factors for development of glaucoma. In conclusion, the indications for premium IOL's in glaucoma patients should include rigorous, individualized selection, along with comprehensive patient counseling.</div></div>","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"48 3","pages":"Article 104431"},"PeriodicalIF":1.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Cayzac , J. Bordes , B. Valero , H. Voisin , M. Sagnard , J. Bertin , T. David , H. El Chehab
{"title":"Cataract surgery without preanesthetic consultation: A 2-year retrospective study","authors":"V. Cayzac , J. Bordes , B. Valero , H. Voisin , M. Sagnard , J. Bertin , T. David , H. El Chehab","doi":"10.1016/j.jfo.2025.104428","DOIUrl":"10.1016/j.jfo.2025.104428","url":null,"abstract":"<div><h3>Purpose</h3><div>Cataract surgery is the most commonly performed procedure in the world. However, certain perioperative modalities remain controversial, and the necessity of systematic performance of a preanesthetic consultation is gradually being questioned. The goal of this study was to investigate the anesthetic and surgical safety of performing cataract surgeries under topical or sub-Tenon's anesthesia without prior preanesthetic consultation.</div></div><div><h3>Methods</h3><div>Thus, we conducted a retrospective study at Sainte-Anne Military Teaching Hospital (Toulon, France) over the period from January 1, 2021, to December 31, 2022, including all patients admitted to the operating room for a phacoemulsification procedure performed under topical or sub-Tenon's anesthesia without prior preanesthetic consultation. Patients were referred to this simplified care pathway in the absence of: predictable surgical difficulties, significant anxiety, risk of agitation or claustrophobia, communication difficulties, lack of cooperation, difficulties in maintaining a motionless supine position, coughing or severe dyspnea or severe allergic history. The eligible patients for this care pathway were selected by the surgeon based on a list of indications. The occurrence of systemic or surgical complications, drug interventions, calls to the anesthesiologist, or unplanned hospitalization in the immediate postoperative period was recorded.</div></div><div><h3>Results</h3><div>One thousand procedures were performed on 654 patients. No major systemic complications were recorded. Surgical complications occurred in 27 procedures (2.7%). Medication was administered to the patient intraoperatively during 413 (41.3%) procedures, mostly antihypertensive drugs (33.1%) and sedatives (11.5%). Aside from drug prescription, 9 calls (0.9%) were made to the anesthesiologist. There were no unplanned hospitalizations in the immediate postoperative period.</div></div><div><h3>Conclusion</h3><div>In our series, performing phacoemulsification procedures under topical or sub-Tenon's anesthesia without prior preanesthetic consultation has shown anesthetic and surgical complication rates comparable to those reported in the literature. Prospective comparative studies are needed to confirm the non-inferiority of this care pathway and to generalize its practice.</div></div><div><h3>Objectif</h3><div>La chirurgie de la cataracte est l’intervention la plus fréquemment réalisée dans le monde. Cependant, certaines modalités périopératoires restent controversées, et la réalisation systématique d’une consultation préanesthésique est progressivement remise en question. L’objectif de cette étude a été d’évaluer la sécurité anesthésique et chirurgicale de la pratique de phacoémulsifications sous anesthésie topique ou sous-ténonienne sans consultation préanesthésique préalable.</div></div><div><h3>Méthodes</h3><div>Il s’agit d’une étude rétrospective, menée à l’hôpital d’instruction de","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"48 3","pages":"Article 104428"},"PeriodicalIF":1.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tumeur vasoproliférative rétinienne (tumeur rétinienne astrocytaire réactionnelle)","authors":"Y.-G. Muller, D. Gaucher","doi":"10.1016/j.jfo.2025.104430","DOIUrl":"10.1016/j.jfo.2025.104430","url":null,"abstract":"<div><div>La tumeur vasoproliférative rétinienne, autrement appelée tumeur rétinienne astrocytaire réactionnelle, est une entité rare se présentant comme une masse de la périphérie rétinienne inférieure, associée à des anomalies vasculaires, et généralement accompagnée de manifestations exsudatives qui conditionnent le pronostic visuel. L’étiologie précise n’est pas connue, néanmoins, la nature principalement astrocytique et réactionnelle de ces lésions semble désormais établie. Elle est classée en primaire ou secondaire, et de nombreuses affections oculaires associées ont ainsi été rapportées, parmi lesquelles la rétinopathie pigmentaire, la pars planite et la maladie de Coats. Le principal diagnostic différentiel est l’hémangioblastome capillaire rétinien de la maladie de von Hippel-Lindau. Le traitement idéal n’est actuellement pas consensuel, et de nombreuses modalités thérapeutiques ont été décrites sur des séries de cas limitées, avec des taux de succès variables. Un traitement s’impose néanmoins en cas de risque visuel, et repose, en fonction des caractéristiques individuelles de la tumeur, sur une approche combinée et raisonnée des différentes modalités thérapeutiques disponibles. Les traitements conservateurs comme la photocoagulation laser, la cryothérapie et/ou la photothérapie dynamique sont ainsi généralement privilégiés pour les tumeurs de petites tailles, tandis que des traitements plus invasifs comme la curiethérapie seront proposés pour des lésions volumineuses ou dont l’activité exsudative ne parvient pas à être contrôlée. La chirurgie vitréorétinienne est fréquemment nécessaire en cas de complications, telles que les décollements de rétine, les membranes épirétiniennes ou les hémorragies du vitré. Les injections intra-vitréennes d’anti-VEGF sont une thérapeutique adjuvante de l’œdème maculaire fréquemment associé.</div></div><div><div>Retinal vasoproliferative tumor, otherwise known as retinal reactive astrocytic tumor, is a rare entity presenting as a mass in the inferior peripheral retina, associated with vascular abnormalities, and usually accompanied by exudative manifestations that affect the visual prognosis. The precise etiology is unknown, but the predominantly astrocytic and reactive nature of these lesions now appears to be established. It is classified as primary or secondary, and numerous associated ocular conditions have been reported, including pigmentary retinopathy, pars planitis and Coats’ disease. The main differential diagnosis is the retinal capillary hemangioblastoma in von Hippel-Lindau disease. There is currently no consensus on the ideal treatment, and numerous therapeutic modalities have been described in limited case series, with variable success rates. Nevertheless, treatment is essential when there is a visual risk and is based on a combined, thoughtful approach to the various therapeutic modalities available, depending on the individual characteristics of the tumor. Conservative treatments such as l","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"48 3","pages":"Article 104430"},"PeriodicalIF":1.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Baoud Ould Haddi , D. Flores Cervantes , E. Dorronzoro Ramírez , V. Blázquez Sánchez , C. Bonnin Arias
{"title":"Comparison of visual function with three intraocular lenses under different illumination conditions","authors":"I. Baoud Ould Haddi , D. Flores Cervantes , E. Dorronzoro Ramírez , V. Blázquez Sánchez , C. Bonnin Arias","doi":"10.1016/j.jfo.2025.104429","DOIUrl":"10.1016/j.jfo.2025.104429","url":null,"abstract":"<div><h3>Purpose</h3><div>To assess the visual function in patients undergoing cataract surgery with three distinct intraocular lens types by evaluating contrast sensitivity under varying photopic and mesopic conditions, as well as examining halo perception.</div></div><div><h3>Methods</h3><div>Visual acuity and contrast sensitivity were measured under photopic and mesopic lighting conditions. Halo perception was also assessed under mesopic conditions. The study involved patients who received one of the following IOLs: Tecnis® Eyhance™, PhysiOL® IsoPure 123™, or AcrySof® IQ Vivity™. The assessment was performed one month after the implantation of the IOL in the second eye.</div></div><div><h3>Results</h3><div>The study included 61 patients and revealed statistically significant differences between the AcrySof® IQ Vivity™ and PhysiOL® IsoPure 123™ IOLs under photopic conditions. The Vivity™ lens demonstrated superior performance compared to the IsoPure 123™ lens at both far (<em>P</em> <!-->=<!--> <!-->0.002) and intermediate distances (<em>P</em> <!-->=<!--> <!-->0.001). Significant differences were also observed between the AcrySof® IQ Vivity™ and Tecnis® Eyhance™ lenses at intermediate distances (<em>P</em> <!-->=<!--> <!-->0.000), with the Vivity™ lens showing better performance than the Eyhance™ lens. Under mesopic conditions, significant discrepancies were found between the PhysiOL® IsoPure 123™ and Tecnis® Eyhance™ lenses at a spatial frequency of 12 cycles per degree (c/g) for long-distance vision (<em>P</em> <!-->=<!--> <!-->0.016), with the Eyhance™ lens outperforming the IsoPure 123™. Furthermore, significant differences were noted when comparing photopic and mesopic conditions for spatial frequencies of 3 cycles per degree (cpg) (<em>P</em> <!-->=<!--> <!-->0.00), 6 cpg (<em>P</em> <!-->=<!--> <!-->0.00), 12 cpg (<em>P</em> <!-->=<!--> <!-->0.013), and 18 cpg (<em>P</em> <!-->=<!--> <!-->0.003), with the Vivity™ lens outperforming other IOL models. The halo perception assessment showed a significant difference between the PhysiOL® IsoPure 123™ and AcrySof® IQ Vivity™ lenses (<em>P</em> <!-->=<!--> <!-->0.012), with the Vivity™ lens exhibiting fewer halos.</div></div><div><h3>Conclusions</h3><div>The study's findings indicate that all three intraocular lens (IOL) models performed well in terms of contrast sensitivity under different lighting conditions. Notably, the AcrySof® IQ VivityTM IOL stood out with the least halo perception.</div></div><div><h3>Objectif</h3><div>Évaluer la fonction visuelle chez les patients opérés de la cataracte avec trois types de lentilles intraoculaires distinctes en évaluant la sensibilité au contraste dans des conditions photopiques et mésopiques variables, ainsi qu’en examinant la perception du halo.</div></div><div><h3>Méthodes</h3><div>La sensibilité au contraste a été mesurée dans différentes conditions d’éclairage, la perception des halos a été évaluée sous des conditions mésopiques, et la satisfactio","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"48 3","pages":"Article 104429"},"PeriodicalIF":1.2,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143175568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Aubert , R. Lecoge , P. Bastelica , M. Atlan , M. Paques , P. Hamard , C. Baudouin , A. Labbé
{"title":"Méthodes d’exploration de la vascularisation de la tête du nerf optique dans la neuropathie glaucomateuse : une revue de la littérature","authors":"T. Aubert , R. Lecoge , P. Bastelica , M. Atlan , M. Paques , P. Hamard , C. Baudouin , A. Labbé","doi":"10.1016/j.jfo.2024.104369","DOIUrl":"10.1016/j.jfo.2024.104369","url":null,"abstract":"<div><div>L’anatomie et la vascularisation de la tête du nerf optique sont complexes et soumises à de nombreuses variations. Le principal facteur de risque de neuropathie glaucomateuse est l’hypertonie oculaire (HTO), mais de nombreux autres facteurs ont été identifiés. Une composante vasculaire semble jouer un rôle important dans la pathogénie et/ou la progression d’une neuropathie glaucomateuse, soit sous l’influence de l’HTO soit comme facteur de risque indépendant, comme notamment dans les glaucomes à pression normale (GPN). En effet, une diminution du flux sanguin oculaire a été identifiée comme un facteur de risque de glaucome. Ainsi de nombreux instruments ont été développés pour explorer notamment la vascularisation de la tête du nerf optique et pour essayer de mieux comprendre les modifications de ce flux sanguin dans la tête du nerf optique en cas de neuropathie glaucomateuse. Nous réalisons dans cette revue de la littérature une mise à jour des différents moyens d’exploration de la vascularisation de la tête du nerf optique, depuis l’angiographie aux techniques les plus modernes avec l’OCT angiographie et le laser Doppler holographique. À travers les résultats retrouvés dans les neuropathies optiques glaucomateuses, nous explorerons ce lien étroit entre la diminution du flux sanguin oculaire et le développement ou la progression d’un glaucome. Une meilleure compréhension de cette physiopathologie ouvre la porte à une meilleure prise en charge de nos patients glaucomateux.</div></div><div><div>The anatomy and vasculature of the optic nerve head are complex and subject to numerous variations. The main risk factor for glaucomatous optic neuropathy is elevated intraocular pressure, but many other factors have been identified. A vascular component seems to play an important role in the pathogenesis and/or progression of glaucomatous optic neuropathy, either under the influence of ocular hypertension or as an independent risk factor, particularly as in normal tension glaucoma (NTG). Reduced ocular blood flow has been identified as a risk factor for glaucoma. Numerous instruments have therefore been developed to explore the vasculature of the optic nerve head and to try to better understand the changes in blood flow in the optic nerve in glaucomatous optic neuropathy. In this review, we provide an update on the various means of imaging the vasculature of the optic nerve head, from angiography to the most modern techniques with angiographic OCT and laser Doppler holography. Using the results found in glaucomatous optic neuropathies, we will explore the close link between reduced ocular blood flow and the development or progression of glaucoma. A better understanding of this pathophysiology opens the door to improved management of our glaucoma patients.</div></div>","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"48 2","pages":"Article 104369"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Grange , V. Gualino , L. Klotz , T. Coutureau , P. Fournié , V. Soler
{"title":"Améliorer la qualité de l’information en chirurgie ambulatoire de cataracte via l’envoi automatisé de SMS : une étude prospective","authors":"C. Grange , V. Gualino , L. Klotz , T. Coutureau , P. Fournié , V. Soler","doi":"10.1016/j.jfo.2024.104368","DOIUrl":"10.1016/j.jfo.2024.104368","url":null,"abstract":"<div><h3>Introduction</h3><div>La chirurgie de cataracte, généralement ambulatoire, est l’intervention la plus pratiquée en France. Les patients sont contactés la veille et le lendemain par téléphone, appels chronophages et soumis à une grande variabilité interopérateur. Les SMS automatisés permettent l’envoi instantané d’informations standardisées à de nombreux patients. Notre objectif était d’évaluer leur impact sur la satisfaction et l’observance.</div></div><div><h3>Matériels et méthodes</h3><div>Notre étude prospective comporte deux bras : groupe intervention recevant les SMS, et groupe contrôle. Nous avons recueilli la satisfaction des patients par un questionnaire et nous avons comparé le respect des consignes préopératoires.</div></div><div><h3>Résultats</h3><div>La moyenne de satisfaction des patients concernant les SMS était de 9,3<!--> <!-->±<!--> <!-->0,9 sur 10. Pour 96 % d’entre eux, les SMS renforçaient la relation avec les professionnels, et 99 % trouvaient ces messages utiles pour mieux suivre les recommandations préopératoires, sans différence significative entre les groupes concernant le respect des consignes.</div></div><div><h3>Discussion</h3><div>Le taux très élevé de satisfaction montre que les patients sont avides d’information. Le sentiment d’amélioration de la relation dans cette population âgée bat en brèche la crainte de déshumanisation de la relation. Les SMS permettent l’envoi et le recueil d’information de manière efficiente avec une bonne acceptabilité.</div></div><div><h3>Conclusion</h3><div>Les SMS automatisés sont une alternative aux appels téléphoniques pour informer les patients avant et après un acte sans l’écueil du fossé digital des applications mobiles. Des études sont en cours pour élargir les indications et confirmer le gain en termes d’observance et de libération du temps soignant.</div></div><div><h3>Introduction</h3><div>Cataract surgery, generally performed on an outpatient basis, is the most common surgical procedure in France. Patients are contacted the day before and the day after by telephone, which is time-consuming and subject to great inter-operator variability. Automated SMS allows standardized information to be sent instantaneously to a large number of patients. Our goal was to assess the impact of SMS messaging on patient satisfaction and compliance.</div></div><div><h3>Materials and methods</h3><div>Our prospective study consisted of two arms: an intervention group receiving SMS, and a control group. We recorded patient satisfaction using a questionnaire and compared compliance with preoperative instructions.</div></div><div><h3>Results</h3><div>Mean patient satisfaction with SMS was 9.3<!--> <!-->±<!--> <!-->0.9 out of 10. For 96% of patients, SMS messages strengthened the relationship with professionals, and 99% found them useful for following preoperative recommendations, with no significant difference between groups in terms of compliance.</div></div><div><h3>Discussion</h3><div>The ve","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"48 2","pages":"Article 104368"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Eslami , M. Ghiasian , B. Mohamadrahimi , N. Jiriaee , A. Eslamighayour
{"title":"Optical coherence tomography (OCT) findings in patients with Parkinson's disease presenting to Farshchian Hospital (Sina) in 2019 compared to the normal population","authors":"F. Eslami , M. Ghiasian , B. Mohamadrahimi , N. Jiriaee , A. Eslamighayour","doi":"10.1016/j.jfo.2024.104379","DOIUrl":"10.1016/j.jfo.2024.104379","url":null,"abstract":"<div><h3>Objective</h3><div>Parkinson's disease is the second most common disease of the central nervous system after Alzheimer's disease. Currently, no blood test or other laboratory tests are available to diagnose this condition. One of the practical methods in diagnosing and evaluating the progress of neurodegenerative diseases is the use of optical coherence tomography (OCT), with which it is possible to accurately measure the thickness of the layers of the retina, as well as the thickness and volume of the macula. The goal of this study was to determine the OCT findings in patients with Parkinson's disease compared to the normal population.</div></div><div><h3>Method</h3><div>This study was conducted in 2019 at the Neurology Clinic of Farshchian Hospital, Hamadan (Iran). Sampling was performed based on the inclusion/exclusion criteria of the study and the required sample size. Patients referred to the Neurology Department of Farshchian Hospital were first examined by a neurologist, then referred to the ophthalmology clinic for a complete ophthalmological examination. OCT imaging was performed by an experienced, skilled optometrist after pupillary dilation with tropicamide drops. RNFL thickness, macula and fovea, and the measured macular volumes were recorded along with other information, including age, sex, disease duration, severity of disease symptoms, and drug use. Finally, the data were analyzed using SPSS version 22 statistical software.</div></div><div><h3>Findings</h3><div>A total of 103 individuals including 49 males (47.6%) and 54 females (52.4%) with a mean age of 70.66 years were examined. The subjects included two groups, patients (53 subjects) and control (50 subjects), who were matched in terms of age and gender distribution. The mean RNFL thickness and macular thickness and volume in the patient group were significantly lower than in the control group (<em>P</em> <!--><<!--> <!-->0.05). There was an inverse relationship between the thickness of the RNFL and the macula with the duration of the disease and the severity of the disease symptoms (<em>P</em> <!--><<!--> <!-->0.05).</div></div><div><h3>Conclusion</h3><div>In this study, a significant decrease in RNFL thickness and macular thickness and volume was shown in patients with Parkinson's disease compared to the age- and sex-matched control group. It can be said that the changes in the macula and RNFL in Parkinson's disease and with progression of the disease are suitable markers for diagnosing and investigating the progression of Parkinson's disease.</div></div><div><h3>Objectif</h3><div>La maladie de Parkinson est la deuxième maladie du système nerveux central la plus répandue après la maladie d’Alzheimer. Actuellement, aucun test sanguin ou autre test de laboratoire n’est disponible pour diagnostiquer cette maladie. L’une des méthodes pratiques de diagnostic et d’évaluation de l’évolution des maladies neurodégénératives est l’utilisation de la tomographie par cohére","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"48 2","pages":"Article 104379"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Panuvéite bilatérale sur salmonellose chronique chez un patient atteint d’un déficit en interleukine 12B","authors":"S. Damoun, E. Chhuy, G. Thuret, P. Gain","doi":"10.1016/j.jfo.2024.104355","DOIUrl":"10.1016/j.jfo.2024.104355","url":null,"abstract":"","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"48 2","pages":"Article 104355"},"PeriodicalIF":1.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142687110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}