Iranian Journal of Otorhinolaryngology最新文献_第6页

SARS-Cov-2 Cycle Threshold Value and Olfactory Dysfunction in COVID-19 Patients. SARS-Cov-2周期阈值与COVID-19患者的嗅觉功能障碍

Iranian Journal of Otorhinolaryngology Pub Date : 2023-09-01 DOI: 10.22038/IJORL.2023.71462.3429

Ali Goljanian Tabrizi, Maliheh Mohseni Ashjerdi, Matin Ghazizadeh, Majid Maleki

{"title":"SARS-Cov-2 Cycle Threshold Value and Olfactory Dysfunction in COVID-19 Patients.","authors":"Ali Goljanian Tabrizi, Maliheh Mohseni Ashjerdi, Matin Ghazizadeh, Majid Maleki","doi":"10.22038/IJORL.2023.71462.3429","DOIUrl":"https://doi.org/10.22038/IJORL.2023.71462.3429","url":null,"abstract":"Introduction: Considering the inconsistent results regarding the association between the severity and duration of olfactory dysfunction (OD), and the viral load in coronavirus disease 2019 (COVID-19) patients, we aimed to conduct this study.Materials and methods: This is a prospective cohort study in which COVID-19 patients were evaluated for the initial cycle threshold value (Ct values) measured by the nasopharyngeal samples along with olfactory function measured by the University of Pennsylvania Smell Identification Test (UPSIT) within 2 months of COVID-19 onset.Results: Among 309 COVID-19 patients who were included in this study, 108 (34.9%), 112 (36.2%) and 89 (28.8%) were normosmic, hyposmic, and anosmic, respectively based on the UPSIT. The severity of COVID-19 and the rate of hospitalization were higher in anosmic patients (p<0.0001, and p<0.0001, respectively). Moreover, significant associations between the initial Ct value and the severity of OD at admission and follow-ups were detected (p<0.0001 and p<0.0001, respectively). Anosmic patients had higher Ct values in comparison with hyposmic (approx. 3-fold) and normosmic (approx. 12-fold) patients. The recovery rate after one- and two-month follow-ups was 47% and 84%, respectively. At the follow-ups, OD-recovered patients significantly had lower Ct values (mean Ct value: 27.79 ± 2 and 28.21 ± 2.08) in comparison with those who have not recovered yet (mean Ct value: 30.19 ± 3.36, and 33.6 ± 3.37) (p<0.0001, and p<0.0001, respectively).Conclusions: Ct value seems to be a significant factor not only in predicting OD severity in COVID-19 patients but also in the OD recovery duration. This finding may be helpful to investigate the underlying mechanisms of OD in COVID-19 patients.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"35 130","pages":"263-273"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10712552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138797697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nasopharyngeal Branchial Cyst and Thornwaldt Cyst in a Patient with Hearing Loss after Coronavirus Infection. 一名感染冠状病毒后听力丧失的患者的鼻咽支气管囊肿和 Thornwaldt 囊肿。

Iranian Journal of Otorhinolaryngology Pub Date : 2023-09-01 DOI: 10.22038/IJORL.2023.71639.3436

Hosna Zobairy, Shahin Rajaeih, Mersad Mehrnahad, Parisa Modaresi, Ahmad Sofi-Mahmudi

引用次数: 0

Comparing the Patients with or without Inner Ear Malformations in Terms of Intra and Postoperative Complications of Cochlear Implantation. 比较有内耳畸形和无内耳畸形患者在人工耳蜗植入术中和术后并发症的情况

Iranian Journal of Otorhinolaryngology Pub Date : 2023-09-01 DOI: 10.22038/IJORL.2023.71581.3433

Adib Molaei Sisakht, Seyed Basir Hashemi, Leila Monshizadeh

{"title":"Comparing the Patients with or without Inner Ear Malformations in Terms of Intra and Postoperative Complications of Cochlear Implantation.","authors":"Adib Molaei Sisakht, Seyed Basir Hashemi, Leila Monshizadeh","doi":"10.22038/IJORL.2023.71581.3433","DOIUrl":"https://doi.org/10.22038/IJORL.2023.71581.3433","url":null,"abstract":"Introduction: Since 20% of the patients with sensorineural hearing loss have confirmed radiographically inner ear malformation, this study aimed to compare the incidence rate of intra and postoperative complications of cochlear implantation amongst the patients with or without inner ear malformations.Materials and methods: In this retrospective study, we evaluated the medical record of 954 patients who had undergone cochlear implantation. Seventeen patients had inner ear malformations and were selected as the case group, and 25 patients with normal inner ear were selected as the control group. Patient's information; including intraoperative complications, post-operative complications and neural response telemetry (NRT) immediately after the surgery were recorded. Finally, the collected data were analyzed, using the SPSS software, version 21.Results: According to the CT-scan findings, the most observed internal ear abnormality was the temporal bone Mondini in 8 patients (47%), and the next inline was the common cavity at a frequency of (23.52%). Cerebrospinal fluid (CSF) gusher was detected in 11 patients (64.7%) of the case group, which was significantly higher than the other group. This includes mild CSF gusher in 7 cases (41.17%) and severe CSF gusher in 5 cases (29.41%). Interestingly, no significant post-operative complications were observed in either group, minor side effects were limited and not significantly different.Conclusion: In conclusion, despite the limitations of cochlear implantation surgery amongst patients with inner ear malformation with potential risk of early or late complications, it can still be recommended as an appropriate procedure to acquire hearing as well as auditory and speech perception.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"35 130","pages":"279-283"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10712546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138797584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Frequency -Specific Air- Conduction and Bone - Conduction Outcomes after Stapedotomy. 镫骨切除术后特定频率的空气传导和骨传导效果。

Iranian Journal of Otorhinolaryngology Pub Date : 2023-09-01 DOI: 10.22038/IJORL.2023.72213.3449

Mohsen Rajati, Ali Ghanbari, Razieh Yousefi, Sadegh Jafarzadeh, Navid Nourizadeh, Mohammad Reza Sharifian, Imaneh Roshanzamir

{"title":"Frequency -Specific Air- Conduction and Bone - Conduction Outcomes after Stapedotomy.","authors":"Mohsen Rajati, Ali Ghanbari, Razieh Yousefi, Sadegh Jafarzadeh, Navid Nourizadeh, Mohammad Reza Sharifian, Imaneh Roshanzamir","doi":"10.22038/IJORL.2023.72213.3449","DOIUrl":"https://doi.org/10.22038/IJORL.2023.72213.3449","url":null,"abstract":"Introduction: The aim of this study was to investigate hearing outcome of stapes surgery, considering the post-operative air and bone conduction (AC&BC) changes, in a frequency specific approach.Materials and methods: This was a retrospective cohort study. A total of 245 ears (231 patients), who underwent Stapedotomy at our tertiary referral center in a period of 5 years were enrolled in the study. Pure tone audiometry (PTA) was evaluated preoperatively and one month postoperatively. AC, BC, and Air-bone gap (ABG) were documented. Moreover, one-year post-op PTA was also recorded for more than a quarter of the cases.Results: Overall, significant improvements were observed in AC thresholds with a mean AC gain of 20.44±13.64 dB. At higher frequencies the results were poorer (AC gain of 27 dB at 250 Hz vs 7 dB at 8000 Hz). ABG significantly improved at all frequencies after one month. BC thresholds were typically better after surgery. However, there appears to be a worsening trend in BC thresholds at frequencies higher than 2000 Hz. In 68 patients with 1-year follow-up, BC thresholds were slightly worse (but not statistically significant) at most frequencies, in comparison to the one-month results.Conclusions: Stapes surgery significantly improves air and bone conduction hearing, particularly at lower frequencies. Nonetheless, there exists a potential for sensorineural hearing loss (SNHL) at high frequencies. However, the changes are insignificant and not within the speech frequencies. Therefore, patients are typically satisfied with the hearing outcome of the surgery.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"35 130","pages":"247-253"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10712547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138797587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multifocal Langerhans' Cell Histiocytosis in an Adult. 成人多灶性朗格汉斯细胞组织细胞增多症。

Iranian Journal of Otorhinolaryngology Pub Date : 2023-07-01 DOI: 10.22038/IJORL.2023.65286.3238

Navid Nourizadeh, Mohammad Reza Majidi, Mohammad Reza Afzalzadeh, Shirin Taraz Jamshidi

引用次数: 0

Subperichondrial Hematoma of Alar Cartilage: A Case Report. 鼻翼软骨软骨下血肿1例。

Iranian Journal of Otorhinolaryngology Pub Date : 2023-07-01 DOI: 10.22038/IJORL.2023.71166.3417

Mehmet Ali Say

引用次数: 0

Perception and Attitude of College Students toward Cosmetic Rhinoplasty. 大学生对鼻整形术的认知与态度。

Iranian Journal of Otorhinolaryngology Pub Date : 2023-07-01 DOI: 10.22038/IJORL.2023.70373.3389

Kamal Alshami, Raghad Alsaati

{"title":"Perception and Attitude of College Students toward Cosmetic Rhinoplasty.","authors":"Kamal Alshami, Raghad Alsaati","doi":"10.22038/IJORL.2023.70373.3389","DOIUrl":"https://doi.org/10.22038/IJORL.2023.70373.3389","url":null,"abstract":"Introduction: Rhinoplasty, a surgery that reshapes the nose to increase facial beauty or to restore the nasal function after a physical defect, is the most popular plastic surgery worldwide and second most common in Saudi Arabia. Regardless of how common this procedure is done in Saudi Arabia, there is a huge lack of studies on how medical students feels and acts towards it. Thus, this study aimed to assess the perception and attitude of cosmetic rhinoplasty among Fakeeh college students in Jeddah, Saudi Arabia.Materials and methods: A validated questionnaire about participants desire to rhinoplasty was randomly distributed among all Fakeeh College students in a simple random technique.Results: 306 participants completed the questionnaire Most responders (60.1%) were happy with their noses. A significant association was noted between gender and desire to undergo rhinoplasty (P=0.034). Also, there is a significant relationship between the participant's desire for rhinoplasty and its cost (P = 0.034).Conclusion: This study showed although rhinoplasty is socially accepted in Saudi Arabia. there is a low desire in college students toward performing rhinoplasty. Factors like cost of surgery or gender affect people's willingness to do rhinoplasty.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"35 129","pages":"199-205"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368169/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9882289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of Uvulopalatoplasty and Nasal Surgery in OSAS Patients. 悬雍垂腭成形术及鼻外科手术治疗OSAS患者的疗效。

Iranian Journal of Otorhinolaryngology Pub Date : 2023-07-01 DOI: 10.22038/IJORL.2023.60817.3098

Gegham Khandanyan, Anna Shukrian, Artur Potosyan, Parounak Zelveian, Artur Shukuryan

{"title":"Effectiveness of Uvulopalatoplasty and Nasal Surgery in OSAS Patients.","authors":"Gegham Khandanyan, Anna Shukrian, Artur Potosyan, Parounak Zelveian, Artur Shukuryan","doi":"10.22038/IJORL.2023.60817.3098","DOIUrl":"https://doi.org/10.22038/IJORL.2023.60817.3098","url":null,"abstract":"Introduction: This study aims to evaluate the effectiveness of simultaneous uvulopalatoplasty and nasal surgery in patients with moderate obstructive sleep apnoea syndrome.Materials and methods: We studied 48 patients with obstructive sleep apnoea syndrome and nasal breathing disorders. The 1st group of 20 patients underwent septoplasty and volumetric tissue reduction of inferior turbinates and the 2nd group of 28 patients underwent septoplasty, volumetric tissue reduction of inferior turbinate, uvulopalatoplasty.Results: In the 1st group, the pre-operative apnoea-hypopnea index median decreased from 22.1 ep/h to 14.9 ep/h after the surgery. Pre-operative median of nasal airflow volume grew from 167.0 cm3 to 609.5 cm3 post-operatively and the loudness of snoring decreased from 2.7±0.2 to 0.7±0.2. In the 2nd group, the apnoea-hypopnea index median decreased from 20.4 ep/h to 5.3 ep./h. The pre-operative median of nasal airflow volume grew from 189.5 cm3 to 519.5 cm3 post-operatively and the loudness of snoring improved from 2.6±0.2 pre-op to 1.1±0.2.Conclusion: Patients with moderate obstructive sleep apnoea syndrome and nasal breathing disorders are advised to have nasal surgery combined with uvulopalatoplasty for a better outcome.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"35 129","pages":"179-187"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9882292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inner Ear Malformation Masquerading as CSF Rhinorrhea - New Perspectives of Management and Literature Review. 伪装成脑脊液鼻漏的内耳畸形-管理的新观点和文献综述。

Iranian Journal of Otorhinolaryngology Pub Date : 2023-07-01 DOI: 10.22038/IJORL.2023.70032.3385

Nidhin Das K, Vidhu Sharma, Sarbesh Tiwari, Amit Goyal

{"title":"Inner Ear Malformation Masquerading as CSF Rhinorrhea - New Perspectives of Management and Literature Review.","authors":"Nidhin Das K, Vidhu Sharma, Sarbesh Tiwari, Amit Goyal","doi":"10.22038/IJORL.2023.70032.3385","DOIUrl":"https://doi.org/10.22038/IJORL.2023.70032.3385","url":null,"abstract":"Introduction: Spontaneous cerebrospinal fluid (CSF) rhinorrhea is rare and may develop secondary to inner ear malformation. A possible diagnosis of CSF leak should be considered in any Pediatric patient who presents with hearing impairment, rhinorrhea, or otorrhea.Case report: We describe a case of 13 months male infant presenting with rhinorrhoea which on evaluation found to be CSF oto-rhinorrhoea due congenital inner ear malformation. Imaging showed malformed inner ear on both sides with CSF leak on left side with bilateral profound sensory neural hearing loss. A multidisciplinary management was considered. Child underwent CSF leak repair on left side followed by Cochlear implantation on right side in another setting.Conclusion: This case is a perfect example to describe the cumbersome management of CSF leak with inner ear anomaly addressing the auditory habilitation on the grounds of recent innovations. As per available literature inner ear anomaly is an important subgroup of population of cochlear implant candidates with promising auditory outcomes.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"35 129","pages":"223-226"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368164/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9882294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Curcumin Prevents Ototoxicity Induced by Cisplatin as Evaluated with OAE. 姜黄素对顺铂所致耳毒性的预防作用

Iranian Journal of Otorhinolaryngology Pub Date : 2023-07-01 DOI: 10.22038/IJORL.2023.71786.3452

Muhammad Dana Arwanda, Tengku-Siti-Hajar Haryuna, Indri Adriztina, Khalisanni Khalid

{"title":"Curcumin Prevents Ototoxicity Induced by Cisplatin as Evaluated with OAE.","authors":"Muhammad Dana Arwanda, Tengku-Siti-Hajar Haryuna, Indri Adriztina, Khalisanni Khalid","doi":"10.22038/IJORL.2023.71786.3452","DOIUrl":"https://doi.org/10.22038/IJORL.2023.71786.3452","url":null,"abstract":"Introduction: This study, assess the efficacy of curcumin therapy in preventing/improving cochlear damage in Rattus norvegicus ototoxic model as evaluated with OAE examination.Materials and methods: This study utilized 27 rats which had been injected with single dose 8mg/KgBB of cisplatin, and then divided into 3 groups. The first group was not given curcumin. The second group received curcumin at a dose of 150 mg/KgBB. The third group received curcumin at a dose of 300 mg/KgBB. Curcumin was given from the time of single dose cisplatin injection (day 0) to day 7. OAE examination was performed on the day before the single dose of cisplatin (day 0), day 3, 4 and 7 after curcumin administration.Results: There was a decline in the average value of SNR in all groups starting from high frequency. However, in the rat groups receiving curcumin there was a slow decrease in the SNR value, which also obtained statistically significant differences in the SNR values of all groups.Conclusion: Administration of certain doses of curcumin may reduce the modest and statistically insignificant decrease in mean SNR values indicating a reduction in ototoxicity from cisplatin.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"35 129","pages":"189-197"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9873171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1