Iranian Journal of Otorhinolaryngology最新文献_第7页

Cavernous Hemangioma of the Sternocleidomastoid Muscle: A Case Report. 胸锁乳突肌海绵状血管瘤1例。

Iranian Journal of Otorhinolaryngology Pub Date : 2023-07-01 DOI: 10.22038/IJORL.2023.67437.3302

Maryam Akbari, Mir Mohammad Jalali, Fatemeh Azad

{"title":"Cavernous Hemangioma of the Sternocleidomastoid Muscle: A Case Report.","authors":"Maryam Akbari, Mir Mohammad Jalali, Fatemeh Azad","doi":"10.22038/IJORL.2023.67437.3302","DOIUrl":"https://doi.org/10.22038/IJORL.2023.67437.3302","url":null,"abstract":"Introduction: Cavernous hemangioma is a venous malformation and intramuscular hemangioma is a rare type of hemangioma. Most of these cases are reported in masseter and temporalis muscles, and the number of patients with hemangioma involving sternocleidomastoid (SCM) muscle is relatively less. The present study reported a case of intramuscular hemangioma and a literature review regarding hemangioma in the sternocleidomastoid muscle.Case report: The present case was a 24-year-old woman with intramuscular hemangioma of the sternocleidomastoid muscle, manifesting a mass in the right supraclavicular region involving the sternocleidomastoid muscle. The woman was treated with surgery and achieved complete treatment. After surgery, the patient was kept under regular follow-up for the last six months without any evidence of recurrence.Conclusion: Intramuscular hemangioma of the sternocleidomastoid muscle is a rare entity that can present as a mass in the neck region. The treatment approach should be considered according to the diagnosis and site of vascular malformation.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"35 129","pages":"217-221"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9879760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Use of Herbal Medicine in Sudden Sensorineural Hearing Loss in Diabetic Patients. 中药治疗糖尿病患者突发性感音神经性耳聋的疗效观察。

Iranian Journal of Otorhinolaryngology Pub Date : 2023-07-01 DOI: 10.22038/IJORL.2023.69813.3368

Ardavan Tajdini, Alireza Karimi Yazdi, Hamideh Ravand, Leyla Sahebi

{"title":"The Use of Herbal Medicine in Sudden Sensorineural Hearing Loss in Diabetic Patients.","authors":"Ardavan Tajdini, Alireza Karimi Yazdi, Hamideh Ravand, Leyla Sahebi","doi":"10.22038/IJORL.2023.69813.3368","DOIUrl":"https://doi.org/10.22038/IJORL.2023.69813.3368","url":null,"abstract":"Introduction: This study was conducted to evaluate the effect of Doluperine® capsule (curcumin, piperine, and gingerol) on hearing recovery in diabetic patients with Sudden Sensorineural Hearing Loss (SSNHL).Materials and methods: Fifty-one diabetic patients with SSNHL were randomized to receive two placebo capsules (group 1), a Doluperine® plus one placebo capsule (group 2), or two Doluperine® capsules (group 3). Moreover, all patients had an injection of dexamethasone in the middle ear.Results: The proportion of significant positive changes in PTA, SDS, and SRT was 45.4%, 45.4%, and 36.37% in group1, 84.6%, 84.6%, and 76.92% in group 2, and 70%, 50.0%, and 80.0% in group 3, respectively. Many patients in group 3 did not respond to treatment in the first month, while they recovered at the end of the second month. The chance of recovery reduced with increased time between the onset of symptoms and treatment (delayed visitation) in group 1; however, this finding was not seen in groups 2 and 3.Conclusion: Doluperine® is recommended as a complementary medicine along with steroid therapy for hearing loss improvement in diabetic patients; moreover, this herbal medicine seems to play an important role in recovery in patients with delayed visitation.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"35 129","pages":"207-215"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368171/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9873173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Intraoperative Findings on Hearing in Revision Ear Surgery. 耳部翻修手术中术中发现对听力的影响。

Iranian Journal of Otorhinolaryngology Pub Date : 2023-05-01 DOI: 10.22038/IJORL.2023.70251.3386

Andro Kosec, Josipa Zivko, Andro Kurtic, Mihael Ries, Dejan Tomljenovic, Jakov Ajduk

{"title":"Impact of Intraoperative Findings on Hearing in Revision Ear Surgery.","authors":"Andro Kosec, Josipa Zivko, Andro Kurtic, Mihael Ries, Dejan Tomljenovic, Jakov Ajduk","doi":"10.22038/IJORL.2023.70251.3386","DOIUrl":"https://doi.org/10.22038/IJORL.2023.70251.3386","url":null,"abstract":"Introduction: Hearing results after chronic ear surgery encompass recurrence, localization and extent of cholesteatoma, type of surgery, ossiculoplasty methods, but rarely interpret intraoperative findings. This study aimed to analyze the impact of intraoperative findings in revision tympanomastoidectomy in predicting postoperative hearing.Materials and methods: This was a retrospective non-randomized cohort of 101 patients treated for recurrent chronic otitis media by tympanomastoidectomy. The patients' demographics, localizations of disease recurrence and perioperative hearing results were analyzed.Results: Logistic regression showed that presence of tympanic perforation (p=0.036), ossicular chain damage (p=0.006), were negatively associated with improved hearing postoperatively. Attic cholesteatoma was associated with better postoperative hearing (p=0.045). Presence of tympanic perforation (p=0.050), alongside perifacial localization of imflammation (p=0.021) and ossicle destruction (p=0.013) were associated with worse postoperative hearing results. Multivariate analysis confirmed that tympanic perforation (p=0.040, F=4.401), and ossicular chain involvement (p=0.025, F=5.249), were consistent negative predictors of hearing improvement, while postoperative deterioration of hearing was associated with tympanic perforation (p=0.038, F=4.465) and facial nerve dehiscence (p=0.045, F=4.160).Conclusions: Comparison of postoperative revision tympanomastoidectomy hearing outcomes revealed significant positive reductions in air-bone gap values, primarily at low and mid frequencies. Postoperative hearing results at high frequencies are not affected by revision surgery.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"35 128","pages":"147-155"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209817/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9550486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Parotid Masson's Tumor in a 29-years-old woman: A Case Report. 29岁女性腮腺马森氏瘤1例。

Iranian Journal of Otorhinolaryngology Pub Date : 2023-05-01 DOI: 10.22038/IJORL.2023.58567.3288

Saleh Mohebbi, Shahriar Zohourian Shahzadi, Ali Jamshidi Naeini

{"title":"Parotid Masson's Tumor in a 29-years-old woman: A Case Report.","authors":"Saleh Mohebbi, Shahriar Zohourian Shahzadi, Ali Jamshidi Naeini","doi":"10.22038/IJORL.2023.58567.3288","DOIUrl":"https://doi.org/10.22038/IJORL.2023.58567.3288","url":null,"abstract":"Introduction: Intravascular papillary endothelial hyperplasia (IPEH) is a papillary hyperplasia of the endothelial vascular cells, also called Masson's tumor. Masson's etiology and risk factors remain unclear but trauma and vascular pathologic conditions may start the tumor process from its common regions like extremities. Common presentations include swelling and mild pain. Our Radiologic modality of choice is Contrast-enhanced MRI which can help us before operating parotidectomy, the gold standard of tumor treatment. As presented in this study, Parotid Masson's tumor, is a very rare form of Masson's,making it even more exceptional.Case report: This paper reports a case of a 29-years-old woman with a mass in herright parotid gland from 17 years ago, which has slowly increased in size during these years. She underwent a total parotidectomy following unsuccessful Fibrovein injections, which caused her inflammation. Embolization was performed before the resection to decrease the risk of its hemorrhage. Postoperative follow-up confirmed the reliability of this treatment method as the patient declared no side effects. Apart from its tough diagnosis, since Masson's tumors, especially the ones that emerge in the parotid, are rare, we decided to introduce this case to deliver more information about the treatment and diagnosis of this rare disease to other colleagues.Conclusions: The prognosis of parotid Masson's is admirable following a total resection. The patient had no postoperative complaints with no need for multiple visits after resection.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"35 128","pages":"165-168"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209814/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9547489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sudden Sensorineural Hearing Loss Associated with Oral Consumption of Hand Sanitizer: A Case Report. 突发性感音神经性听力损失与口服洗手液相关:1例报告。

Iranian Journal of Otorhinolaryngology Pub Date : 2023-05-01 DOI: 10.22038/IJORL.2023.70374.3390

Arshit Kataria, Siddharth Jain, Manika Arora, Sonal Mishra

{"title":"Sudden Sensorineural Hearing Loss Associated with Oral Consumption of Hand Sanitizer: A Case Report.","authors":"Arshit Kataria, Siddharth Jain, Manika Arora, Sonal Mishra","doi":"10.22038/IJORL.2023.70374.3390","DOIUrl":"https://doi.org/10.22038/IJORL.2023.70374.3390","url":null,"abstract":"Introduction: Pediatric sudden sensorineural hearing loss (SSNHL) is a rare otological emergency. With the emergence of the Coronavirus 19 pandemic, alcohol-based hand sanitizers are among the essential household items. Many hand sanitizers are frequently coupled with scents that young children may find pleasant.Case report: A 5-year-old girl presented to our clinic with hearing loss after the consumption of alcohol-based hand sanitizer. A pure tone audiogram showed bilateral SSNHL. The child was prescribed systemic corticosteroids resulted in a slight improvement in hearing thresholds. The child was followed up at 6 and 18 months showing no further improvement in hearing thresholds.Conclusion: Although various infective, vascular, and immune responses have been proposed, alcohol-based hand sanitizer consumption has not been reported to present with SSNHL to the best of our knowledge. In the current scenario of the Coronavirus pandemic, otorhinolaryngologists must keep in mind that SSNHL may occur as a result of hazardous alcohol-based hand disinfectant consumption.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"35 128","pages":"173-178"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9599556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Morphometry around Cochleostomy Site to Aid Safe Cochlear Implantation. 人工耳蜗造口术周围形态测量有助于安全人工耳蜗植入。

Iranian Journal of Otorhinolaryngology Pub Date : 2023-05-01 DOI: 10.22038/IJORL.2023.65579.3249

Yellur Kavitha, Upendra Kumar Joish

{"title":"Morphometry around Cochleostomy Site to Aid Safe Cochlear Implantation.","authors":"Yellur Kavitha, Upendra Kumar Joish","doi":"10.22038/IJORL.2023.65579.3249","DOIUrl":"https://doi.org/10.22038/IJORL.2023.65579.3249","url":null,"abstract":"Introduction: In morphologically normal-appearing inner ears, measurements of the distance between the round window and carotid canal (RCD), the maximum diameter of the basal turn of the cochlea next to the round window (BD), and the thickness of the promontory (PT) just lateral to the basal turn may be used as guide for safe cochleostomy and implant placement.Materials and methods: From January to March 2022, a cross-sectional observational study was carried out in a tertiary care hospital. The round window to carotid canal distance (RCD), the largest diameter of the cochlea's basal turn next to the round window (BD), and the thickness of the promontory immediately lateral to the basal turn (PT) were measured using CT temporal bone images of 150 persons without cochlear abnormalities. The values obtained were compared using Paired T-test for significance of difference between both genders and sides.Results: A total of 150 participants-75 men and 75 women-with a mean age of 37.5 years were enrolled in the study. With a range of 7.18 mm to 10.52 mm, the mean RCD was 8.84 mm (SD 0.8 mm). The mean BD was 2.27 mm (SD 0.4 mm), while the mean PT was 1.15 mm (SD 0. mm). The values obtained did not differ significantly in both the genders and the right and left sides (p = 0.37 and 0.24, respectively).Conclusion: The present study has defined and calculated pertinent measures at cochleostomy site that will aid safe electrode insertion and prevent misplacement.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"35 128","pages":"119-123"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9544792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of Silicon T-Tube for Subglottic Stenosis and Tracheal Stenosis. 硅t型管在声门下狭窄和气管狭窄中的应用。

Iranian Journal of Otorhinolaryngology Pub Date : 2023-05-01 DOI: 10.22038/IJORL.2023.67492.3308

Chethana Ramesh, Arun Dehadaray, Maitri Kaushik, Prasun Mishra, Simran Sidhu

{"title":"Use of Silicon T-Tube for Subglottic Stenosis and Tracheal Stenosis.","authors":"Chethana Ramesh, Arun Dehadaray, Maitri Kaushik, Prasun Mishra, Simran Sidhu","doi":"10.22038/IJORL.2023.67492.3308","DOIUrl":"https://doi.org/10.22038/IJORL.2023.67492.3308","url":null,"abstract":"Introduction: The management of subglottic and tracheal stenosis is challenging for any ENT surgeon. The treatment choice depends on the site, severity of stenosis, patient symptoms, and surgeon preferences. The various options for the management include endoscopic balloon dilatation, various types of laryngotracheoplasty, resection anastomosis, and insertion of a silicon T-tube. Compared to the above, silicon T-tube stenting is a better alternative, as it is a onetime procedure, easy to perform with fewer chances of complications. Shiann Yann lee technique is a form of laryngotracheoplasty with long-term stenting using silicon T-tube. This article analyzed our silicon T-Tube insertion result in patients with subglottic and tracheal stenosis using this technique.Materials and methods: In this retrospective study, we included a total of 21 patients with subglottic and tracheal stenosis who underwent silicon T-Tube insertion. Data regarding the site of stenosis, procedure, complications, and outcome were analyzed.Results: Out of 21 patients, nine patients had subglottic stenosis (42.8%), 8 had cervical tracheal stenosis (38.09%), 3 had thoracic tracheal stenosis (14.28%), and 1 (4.7%) had combined subglottic and cervical tracheal stenosis. Out of 21 patients,7 (33.3%) have undergone successful removal of silicon T-Tube so far, one death due to medical reasons, and 13 patients (61.9%) are still on Silicon tube on regular follow-up. They are comfortable with the tube in situ.Conclusions: Silicon T-Tube for benign acquired laryngotracheal stenosis with Shiann Yann Lee's technique is effective, safe with less complication, and good acceptability and tolerance by the patient.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"35 128","pages":"125-131"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9547487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Muscle Variant of the Lateral Neck Region: The Cleido-Vertebral Muscle. 颈部外侧区域的肌肉变异:锁骨椎肌。

Iranian Journal of Otorhinolaryngology Pub Date : 2023-05-01 DOI: 10.22038/IJORL.2023.70325.3388

Daniela Parrino, Enzo Emanuelli

{"title":"A Muscle Variant of the Lateral Neck Region: The Cleido-Vertebral Muscle.","authors":"Daniela Parrino, Enzo Emanuelli","doi":"10.22038/IJORL.2023.70325.3388","DOIUrl":"https://doi.org/10.22038/IJORL.2023.70325.3388","url":null,"abstract":"Introduction: Anatomical variations of the neck muscles have previously been reported, involving in particular the omohyoid and sternothyroid muscles. We herein report a novel variant neck muscle found during a routine surgical procedure.Case report: A 63-year-old women underwent a pelvi-mandibulectomy with bilateral neck dissection for a squamous cell carcinoma of the floor of mouth pT3N1. On the right neck dissection, the present peculiar muscle was discovered. It was located in the lateral region of the neck, deeply to the sternocleidomastoid muscle and caudally to the hyoid bone. It took origin from the sixth cervical vertebrae's transverse process and attached caudally to the middle third of the clavicular bone, after having passed superficially to the omohyoid muscle's intermediate tendon.Conclusions: Neck muscles are important during head and neck surgery due to their significance as surgical landmarks and their relationship with noble vessels. Being aware of possible variant that can alter classical anatomical reference points is important to prevent iatrogenic trauma.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"35 128","pages":"169-172"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9547492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Foramen of Huschke: It's Relationship with Volume of Mastoid Pneumatization. Huschke孔:与乳突充气体积的关系。

Iranian Journal of Otorhinolaryngology Pub Date : 2023-05-01 DOI: 10.22038/IJORL.2023.66453.3282

Şahinde Atlanoglu, Muhammed Fatih Topuz

{"title":"Foramen of Huschke: It's Relationship with Volume of Mastoid Pneumatization.","authors":"Şahinde Atlanoglu, Muhammed Fatih Topuz","doi":"10.22038/IJORL.2023.66453.3282","DOIUrl":"https://doi.org/10.22038/IJORL.2023.66453.3282","url":null,"abstract":"Introduction: The foramen of Huschke (FH) is a developmental bone defect located anteroinferior to the external auditory canal. In this study, the frequency of FH and the presence of TMJ herniation into the external auditory canal were investigated using high-resolution computed tomography (HRCT) of the temporal bone in patients with FH. In addition, it was aimed to determine whether there is a relationship between the degree of mastoid pneumatization and mastoid volume and the presence of FH.Materials and methods: The HRCT images of 352 patients were retrospectively evaluated for the presence of FH and TMJ herniation into the external auditory canal. The degree of pneumatization was determined in 50 patients with FH and 53 patients without FH, and the mastoid volume was measured.Results: Of the 704 temporal bones, 50 (7.1%) were detected to have FH 16 (4.5%) on the right and 34 (9.7%) on the left. The incidence of FH was higher in women on the right than in men (p<0.01). There was strong correlation between the FH width and age for the left side (r=0.466, p<0.01). The mastoid volume was 3.2-15.9 cm3 in the patients with FH and 3.2-16.2 cm3 in those without FH. The degree of pneumatization and mastoid volume did not significantly differ between the both groups (p>0.05). TMJ herniation into the external auditory canal was detected in one of the patients with FH.Conclusions: We could not find a relationship between mastoid bone pneumatization and FH development. The presence of FH should be detected before TMJ and ear surgeries to prevent possible complications.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"35 128","pages":"133-139"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209811/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9544789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Toxoplasma Lymphadenopathy: A Comparative Diagnostic Assessment of Clinical, Serological and Histopathological Findings. 弓形虫淋巴结病:临床、血清学和组织病理学结果的比较诊断评估。

Iranian Journal of Otorhinolaryngology Pub Date : 2023-05-01 DOI: 10.22038/IJORL.2023.64479.3205

Samah Abbas Hammadi, Abbas Jaafar Khaleel Al-Anbari, Bassam Maddah Al-Alosi

{"title":"Toxoplasma Lymphadenopathy: A Comparative Diagnostic Assessment of Clinical, Serological and Histopathological Findings.","authors":"Samah Abbas Hammadi, Abbas Jaafar Khaleel Al-Anbari, Bassam Maddah Al-Alosi","doi":"10.22038/IJORL.2023.64479.3205","DOIUrl":"https://doi.org/10.22038/IJORL.2023.64479.3205","url":null,"abstract":"Introduction: Toxoplasma Gondii (TG) is a zoonotic protozoan with extensive symptomatology. Toxoplasmic lymphadenopathy is considered an affirmative sign and is proved by a biopsy of the enlarged nodule. This study was conducted to compare the clinical, serological, and histopathological findings for the diagnosis of toxoplasmic lymphadenopathy.Materials and methods: This study involved biopsy examinations from twelve cases with TG lymphadenopathy. ELISA serological tests were performed for TG specific IgM and IgG immunoglobulins. PCR was done to ratify the results obtained by ELISA.Results: The ages of the patients ranged from 15 to 48 years (mean=27.8). Most of the cases are male n=8(66.7%), while female n=4(33.3%). The asthenia was not only the most frequent clinical presentation (83.3%), but it also last longer. All cases had a positive biopsy. Eight (67.7%) cases revealed seropositivity. Two of them had positive PCR in those who were positive IgM, suggesting that the infection was acute. Six (50%) cases revealed positive IgG tests, while those with negative serology were 4(33.3%). The site of lymph nodes involvement had been assessed and mostly cervical (91.6%).Conclusion: The histopathological results yielded 100% positive findings, thus biopsy was very important in the diagnosis and differential diagnosis of lymph nodes enlargement. The chronic phase of toxoplasmosis does not show the protozoa in the blood causing an absent DNA band for amplification of the PCR cycles, which could explain the lack of bands particular for TG. A negative serological test does not exclude toxoplasmic lymphadenitis, especially in immune-compromised patients.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"35 128","pages":"157-163"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209818/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9544794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0