Iranian Journal of Otorhinolaryngology最新文献_第3页

Correlation Between Indoxyl Sulfate in Chronic Kidney Disease and Olfactory Dysfunction. 硫酸吲哚酚与慢性肾病患者嗅觉功能障碍的相关性研究。

Iranian Journal of Otorhinolaryngology Pub Date : 2025-01-01 DOI: 10.22038/ijorl.2024.77737.3632

Irnanda-Warda-Rizki Nasution, Tengku-Siti-Hajar Haryuna, Delfitri Munir, Syafrizal Nasution, Putri-Chairani Eyanoer, Siti Nursiah, Ramlan Sitompul

{"title":"Correlation Between Indoxyl Sulfate in Chronic Kidney Disease and Olfactory Dysfunction.","authors":"Irnanda-Warda-Rizki Nasution, Tengku-Siti-Hajar Haryuna, Delfitri Munir, Syafrizal Nasution, Putri-Chairani Eyanoer, Siti Nursiah, Ramlan Sitompul","doi":"10.22038/ijorl.2024.77737.3632","DOIUrl":"10.22038/ijorl.2024.77737.3632","url":null,"abstract":"Introduction: Olfactory dysfunction is prevalent among individuals with chronic kidney disease (CKD), with prevalence escalating alongside disease severity. The uremic toxin we observed in this study is Indoxyl sulfate (IS), a potent uremic toxin that markedly accumulates in the plasma of patients with chronic insufficiency. Olfactory damage may occur in the setting of neuronal damage due to renal failure.Materials and methods: 27 patients, a total sample in this study with diagnosed chronic kidney disease within stage 5 on regular hemodialysis, were examined for indoxyl sulfate levels in blood plasma and then examined for their olfactory function using the Sniffin' Sticks test. A correlation analysis was conducted between indoxyl sulfate levels and olfactory function test results in patients with CKD.Results: The Pearson correlation test revealed a strong, significant negative correlation between indoxyl sulfate levels and olfactory function (r = -0.613; p = 0.001). Additionally, correlations were found between indoxyl sulfate levels and each component of olfactory function: threshold value (r = -0.408; p = 0.035), discrimination (r = -0.807; p = 0.001), and identification (r = -0.703; p = 0.001).Conclusion: Olfactory function is compromised in individuals with chronic renal disease and correlates with the level of accumulation of the uremic toxin indoxyl sulfate.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"37 1","pages":"19-25"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11750640/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Obstructive Pharyngo-Laryngeal Hematoma Complicating Oral Anticoagulation: Case Report. 咽喉梗阻性血肿并发口服抗凝1例。

Iranian Journal of Otorhinolaryngology Pub Date : 2025-01-01 DOI: 10.22038/ijorl.2025.82416.3772

Maissa Lajhouri, Houda Chahed, Rania Laajailia, Rihab Lahmer, Azza Mediouni, Najeh Beltaief

{"title":"Obstructive Pharyngo-Laryngeal Hematoma Complicating Oral Anticoagulation: Case Report.","authors":"Maissa Lajhouri, Houda Chahed, Rania Laajailia, Rihab Lahmer, Azza Mediouni, Najeh Beltaief","doi":"10.22038/ijorl.2025.82416.3772","DOIUrl":"10.22038/ijorl.2025.82416.3772","url":null,"abstract":"Introduction: Spontaneous pharyngo-laryngeal hematoma in patients receiving oral anticoagulants is rare and potentially fatal because of upper airway obstruction. Many risk factors can cause potential hemorrhagic complications, such as drug interactions.Case report: We present the case of a 74-year-old man who was on oral anticoagulation by acenocoumarol and presented with acute laryngeal dyspnea. The final diagnosis of pharyngo-laryngeal hematoma secondary to hypercoagulation was made based on the clinical, biological, and radiological features. Therefore, conservative management was initiated. Drug interactions between anticoagulants and macrolides were the probable underlying causes of excessive anticoagulation.Conclusion: Pharyngo-laryngeal hematoma should be considered in patients receiving anticoagulant therapy with symptoms of upper airway obstruction. Drug interactions may be the underlying cause of hypercoagulation, so medications should be carefully prescribed to these patients.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"37 3","pages":"165-168"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

What Did We Learn from Our Cochlear Implant Revisions? 我们从人工耳蜗修复中学到了什么？

Iranian Journal of Otorhinolaryngology Pub Date : 2025-01-01 DOI: 10.22038/ijorl.2025.77740.3612

Cigdem Kalaycik Ertugay, Ozgur Yigit, Ecem Sevim Akı

{"title":"What Did We Learn from Our Cochlear Implant Revisions?","authors":"Cigdem Kalaycik Ertugay, Ozgur Yigit, Ecem Sevim Akı","doi":"10.22038/ijorl.2025.77740.3612","DOIUrl":"10.22038/ijorl.2025.77740.3612","url":null,"abstract":"Introduction: We aimed to report our clinic's 11-year experience with cochlear implant (CI) revision surgeries.Materials and methods: This was a retrospective observational study. Patients who underwent CI and revision surgery at the same tertiary institution were enrolled in the study. Patients whose primary surgery was performed at another institution were excluded from the study. The patients' clinical charts, surgical records, and audiological and oral language outcomes were retrospectively examined.Results: Thirty-three (29 children, 4 adults) of 720 patients (871 CI) at our clinic required revision surgery, representing a revision surgery rate of 4.58%. The most common reason for revision was device failure (10 patients), followed by skin and electrode problems, with electrode tip fold-over in 6 patients, a broken electrode cable in 1 patient, skin flap complications in 6 patients, displacement of the magnet in 1 patient, cholesteatoma in 1 patient, electrode migration in 6 patients, misplacement of the electrode array into the internal acoustic canal in 1 patient, and explantation of the electrode cable in the external auditory canal in 1 patient. We had only one major complication after revision surgery.Conclusion: We recommend performing routine postoperative imaging, even if intraoperative telemetries are normal, to diagnose electrode misplacement or electrode tip fold-over. Additionally, we recommend long-term regular follow-up of children, in particular, because our study showed that the number of revision surgeries was higher in children who received implants at an early age.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"37 3","pages":"143-150"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126201/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laryngeal Frame Involvement as The First Sign of Wegener's Granulomatosis. 喉架受累是韦格纳肉芽肿病的第一征象。

Iranian Journal of Otorhinolaryngology Pub Date : 2025-01-01 DOI: 10.22038/ijorl.2024.81617.3746

Davide Burrascano, Barbara Verro, Gaetano Ottoveggio, Ada Maria Florena, Carmelo Saraniti

{"title":"Laryngeal Frame Involvement as The First Sign of Wegener's Granulomatosis.","authors":"Davide Burrascano, Barbara Verro, Gaetano Ottoveggio, Ada Maria Florena, Carmelo Saraniti","doi":"10.22038/ijorl.2024.81617.3746","DOIUrl":"10.22038/ijorl.2024.81617.3746","url":null,"abstract":"Introduction: Granulomatosis with Polyangiitis (GPA), also known as Wegener's Granulomatosis, is an ANCA-associated vasculitis that primarily affects small vessels, leading to necrotizing granulomatous reactions in the airways and small vessels. The etiology remains uncertain.Case report: We report the case of a woman in her 70s, who was previously tracheostomized at another facility and was presented to our attention with glottic-subglottic stenosis. We performed a lysis of glottic synechia and subglottic debulking via transoral laser microsurgery, yielding satisfactory results over the short term. However, a relapse occurred within two months, along with ulcerative lesions on the nasal septum. Biopsies revealed multinucleated giant cells and inflammation suggestive of vasculitis. Based on the histological and clinical features, a diagnosis of vasculitis was considered. Anti-Neutrophil Cytoplasmic Antibodies testing was positive. A rheumatological examination confirmed the hypothesis of Granulomatosis with Polyangiitis. The lack of typical symptoms was the main reason for the delayed diagnosis.Conclusion: Involvement of the subglottic region and the upper portion of the trachea is a rare but severe complication of GPA. The current literature reports only few cases of laryngeal stenosis, with poor prognosis. Histological examinations of biopsied laryngeal tissue showed significant but non-specific inflammation, contributing to the delay in diagnosis. There are still no precise guidelines for the surgical treatment of subglottic stenosis. This case underscores the importance of considering laryngeal involvement in GPA for early diagnosis and timely intervention to prevent serious complications in order to improve patient outcomes.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"37 2","pages":"95-98"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11949434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Junctional Epidermolysis Bullosa Associated Laryngeal Stenosis: A Case Report and Review of Literature. 交界性表皮松解症伴有喉狭窄：病例报告和文献综述。

Iranian Journal of Otorhinolaryngology Pub Date : 2024-09-01 DOI: 10.22038/ijorl.2024.78360.3639

Firyal Balushi, Ziyad Al Harrasi, Maathir Al Farsi, Marwa Al Qurani

引用次数: 0

Life-Threatening Bleeding in Atypical Pleomorphic Adenoma of the Soft Palate. 软腭非典型多形性腺瘤危及生命的出血。

Iranian Journal of Otorhinolaryngology Pub Date : 2024-09-01 DOI: 10.22038/ijorl.2024.75295.3538

Francesca Piccinini, Mario Borgione, Giuseppe Riva, Giancarlo Pecorari

引用次数: 0

Masseteric Vestibular Evoked Myogenic Potentials in Vestibular Neuritis: A Case Series. 前庭神经炎的颚前庭诱发肌源性电位：病例系列。

Iranian Journal of Otorhinolaryngology Pub Date : 2024-09-01 DOI: 10.22038/ijorl.2024.77538.3598

Anjana Rajesh, Anuj Kumar Neupane

引用次数: 0

Submandibular Gland Preservation in Oral Cavity Squamous Cell Carcinomas: Our Analysis at A Tertiary Care Hospital. 口腔鳞状细胞癌中的颌下腺保留：我们对一家三级医院的分析

Iranian Journal of Otorhinolaryngology Pub Date : 2024-09-01 DOI: 10.22038/ijorl.2024.75754.3608

Shahid Rasool, Ayushi Manghani, Shilpam Sharma, Zohda Tayyaba, Sabina Khan, Zarreen Parvez, Neha Dillon, Khaja Naseeruddin, Shamaaila Aftab, Arsal Usman, Hafsa Khan

{"title":"Submandibular Gland Preservation in Oral Cavity Squamous Cell Carcinomas: Our Analysis at A Tertiary Care Hospital.","authors":"Shahid Rasool, Ayushi Manghani, Shilpam Sharma, Zohda Tayyaba, Sabina Khan, Zarreen Parvez, Neha Dillon, Khaja Naseeruddin, Shamaaila Aftab, Arsal Usman, Hafsa Khan","doi":"10.22038/ijorl.2024.75754.3608","DOIUrl":"https://doi.org/10.22038/ijorl.2024.75754.3608","url":null,"abstract":"Introduction: Surgical excision forms the principal treatment of oral cavity squamous cell carcinomas. The comprehensive surgical management consists of Wide Local Excision of the tumor and Neck Dissection with removal of Submandibular gland. The submandibular gland accounts for 70-90 % of unstimulated salivary volume. Its excision as a part of neck dissection has been found to cause high Incidence (21% vs 7%) of postoperative xerostomia. Recent studies have highlighted that the preservation of the SMG is possible and oncologically safe in early-grade OCSCC with N0 neck as the involvement of SMG in such cases is low and its preservation decreases the chances of xerostomia.Materials and methods: 80 subjects were included in the study to estimate the prevalence of metastatic submandibular gland involvement in oral cavity squamous cell carcinomas. The presence of metastasis into the salivary gland was studied and the mechanism/route of involvement was analysed. The comparison was made between the early and advanced tumors for SMG metastasis irrespective of the primary subsite involvement.Results: In the current study low prevalence (6.2 %) of metastasis to SMG was seen. It was seen in high-grade tumors only. None of the early-grade tumors showed any evidence of SMG metastasis. The most common pattern (80%) of glandular involvement was a direct extension from the primary tumor.Conclusions: Our study concludes that SMG preservation neck dissections can be carried out in early-grade OCSCC irrespective of primary tumor site involvement. The advantages of preserving the SMG are multiple. Furthermore, the morbidity is markedly decreased with its preservation without any compromise on oncological safety.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"36 5","pages":"581-586"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11421762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mupirocin Ointment Effect on Polyposis Recurrence After Sinus Surgery. 莫匹罗星软膏对鼻窦手术后息肉复发的影响

Iranian Journal of Otorhinolaryngology Pub Date : 2024-09-01 DOI: 10.22038/ijorl.2024.70685.3405

Alireza Mohebbi, Maryam Mohsenian, Morvarid Elahi, Sara Minaeian

{"title":"Mupirocin Ointment Effect on Polyposis Recurrence After Sinus Surgery.","authors":"Alireza Mohebbi, Maryam Mohsenian, Morvarid Elahi, Sara Minaeian","doi":"10.22038/ijorl.2024.70685.3405","DOIUrl":"https://doi.org/10.22038/ijorl.2024.70685.3405","url":null,"abstract":"Introduction: Staphylococcus aureus is an identified pathogen involved in the recurrence of symptoms in patients with chronic rhinosinusitis with nasal polyps. We investigated the effectiveness of a topical ointment of mupirocin applied in the nasal vestibule in lessening symptom recurrence and improving the efficiency of functional endoscopic sinus surgery.Materials and methods: Patients with chronic rhinosinusitis, nasal polyps, and a positive nostril culture for Staphylococcus aureus were included in a clinical trial. The right nostril was determined as the intervention group (applying mupirocin ointment) and the left as the control group (applying vitamin A ointment). Lund-Mackay radiological scores and Lund-Kennedy endoscopic scores were examined at the time of diagnosis and six months later.Results: Among 60 patients with chronic rhinosinusitis with nasal polyps, 91.6% were positive for nostril Staphylococcus aureus. Comparing the average of the diagnostic radiological and endoscopic scores with the follow-up values in both groups indicated a significant improvement after surgery (P-value=0.001, 0.001). However, there was no significant difference in the radiological and endoscopic score improvements between the study and control groups (P-value > 0.56, 0.74).Conclusion: Nasal mupirocin administration following endoscopic sinus surgery cannot significantly prevent symptom recurrence in chronic rhinosinusitis with nasal polyps.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"36 5","pages":"573-580"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11421765/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Dentofacial Angles in Children with Severe Adenoid Hypertrophy. 评估严重腺样体肥大患儿的颌面角度

Iranian Journal of Otorhinolaryngology Pub Date : 2024-09-01 DOI: 10.22038/ijorl.2024.77257.3584

Masoumeh Eslami, Nafiseh Alipour

{"title":"Evaluation of Dentofacial Angles in Children with Severe Adenoid Hypertrophy.","authors":"Masoumeh Eslami, Nafiseh Alipour","doi":"10.22038/ijorl.2024.77257.3584","DOIUrl":"https://doi.org/10.22038/ijorl.2024.77257.3584","url":null,"abstract":"Introduction: Hypertrophy of adenoids is a common condition in childhood, resulting in obstructive symptoms such as sleep apnea, snoring, and rhinosinusitis. Adenotonsillectomy is recommended to improve prognosis and quality of life. This case-control study compared facial angles and lip position related to dentofacial and mouth growth in symptomatic children with adenoid hypertrophy and asymptomatic control groups.Materials and methods: The study included children aged 5 to 7 who presented with obstructive symptoms and confirmed severe adenoid hypertrophy in lateral neck radiography. Standard lateral photography was taken. The Nasofacial and Nasomental angles, and upper and lower lip positions and their distance behind the Ricketts line, were measured and compared with the normal control group.Results: This study included 54 children with severe adenoid hypertrophy and 66 normal children. Facial angles were not significantly different between the two groups, but the mean horizontal position of the upper and lower lip in children with adenoid hypertrophy was significantly lower than in the control group (P value = 0.05). The lips were too close to the Ricketts line compared with the control group.Conclusions: This research demonstrates that children with severe adenoid hypertrophy have more dentofacial disorders than others. Adenotonsillectomy surgery is necessary for children with obstructive symptoms caused by tonsil enlargement, and if symptoms like snoring persist post-surgery, complementary orthodontic treatments should be considered.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"36 5","pages":"587-593"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11421768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0