Iranian Journal of Otorhinolaryngology最新文献_第2页

Epidemiology of Angina Bullosa Hemorrhagica: A Retrospective study.

Iranian Journal of Otorhinolaryngology Pub Date : 2025-01-01 DOI: 10.22038/ijorl.2024.71853.3442

Meenakshi Sachdeva, Pratik Kumar, Keshav Gupta

{"title":"Epidemiology of Angina Bullosa Hemorrhagica: A Retrospective study.","authors":"Meenakshi Sachdeva, Pratik Kumar, Keshav Gupta","doi":"10.22038/ijorl.2024.71853.3442","DOIUrl":"10.22038/ijorl.2024.71853.3442","url":null,"abstract":"Introduction: Angina Bullosa Hemorrhagica (ABH) is a rare condition characterized by hemorrhagic blisters and is often asymptomatic. These lesions appear more commonly in the oral cavity and oropharynx and are often misdiagnosed. A retrospective cross-sectional study was performed in clinically confirmed cases of ABH to study its epidemiology, etiology and presentation in a tertiary care hospital in Southern Asia.Materials and methods: Total of 8 patients of ABH were evaluated and included in the present study. All clinical data and track records were assessed by the medical records department. Cases were studied and results were interpreted. Results: Total of 8 cases were enrolled with male-to-female ratio of 0.6:1 and middle age as the most common age of presentation. Buccal mucosa was the most common site involved with average lesion size of 1.6 cm. Masticating trauma was the most common etiological risk factor. Majority patients were asymptomatic with spontaneous resolution of lesions in all the cases.Conclusion: Due to smaller number of studies reported, the lesions of ABH remained poorly understood with uncertain etiology. The knowledge of characteristic clinical features of the lesion and pattern of spontaneous healing is of utmost importance as a lesion of ABH can share some features with other serious disorders, thereby delaying the diagnosis. A thorough clinical history and examination of the lesion should always be done to establish an accurate diagnosis. Due to its completely benign nature, proper counseling of the patients must be ensured for better patient compliance.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"37 1","pages":"41-45"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11750637/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Relationship Between Obesity and Otitis Media with Effusion in Children.

Iranian Journal of Otorhinolaryngology Pub Date : 2025-01-01 DOI: 10.22038/ijorl.2025.79859.3688

Saleh Aghaei, Bijan Khademi, Mohammad Faramarzi, Amirhossein Babaei

{"title":"The Relationship Between Obesity and Otitis Media with Effusion in Children.","authors":"Saleh Aghaei, Bijan Khademi, Mohammad Faramarzi, Amirhossein Babaei","doi":"10.22038/ijorl.2025.79859.3688","DOIUrl":"10.22038/ijorl.2025.79859.3688","url":null,"abstract":"Introduction: Otitis media with effusion (OME) is a widespread condition affecting children globally. This study aimed to assess the relationship between obesity in pediatric populations and the risk of developing OME.Materials and methods: This retrospective observational study was performed in 2020 at Khalili and Dastgheib hospitals, affiliated with Shiraz University of Medical Sciences in Shiraz, Iran. The study included all children aged 2 to 15 years with a confirmed OME diagnosis. Participants in the non-OME group were chosen from children who did not have OME.Results: A total of 148 healthy individuals were included in the non-OME group, while the OME group comprised 110 patients. Statistical analysis revealed that the mean age (p=0.040), weight (p<0.001), height (p=0.024), BMI (p=0.023), and BMI percentile (p=0.023) were significantly greater in the OME group compared to the non-OME group. Additionally, there was a higher proportion of males in the OME group (63.6%) compared to the non-OME group (44.0%), with this difference being statistically significant (p=0.001). Logistic regression analysis indicated that factors such as older age (p=0.023), male gender (p=0.001), and elevated BMI percentile (p=0.004) were significantly associated with the presence of OME.Conclusion: This research indicates that there is a correlation between obesity and a heightened risk of OME.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"37 2","pages":"79-84"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11949430/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Intra-Operative Topical 5-Fluorouracil Post-Functional Endoscopic Sinus Surgery: A Randomized Controlled Trial.

Iranian Journal of Otorhinolaryngology Pub Date : 2025-01-01 DOI: 10.22038/ijorl.2025.80571.3709

Lekhaa Mohanraj, Somu Lakshmanan, Urvashi Singh

{"title":"Effect of Intra-Operative Topical 5-Fluorouracil Post-Functional Endoscopic Sinus Surgery: A Randomized Controlled Trial.","authors":"Lekhaa Mohanraj, Somu Lakshmanan, Urvashi Singh","doi":"10.22038/ijorl.2025.80571.3709","DOIUrl":"10.22038/ijorl.2025.80571.3709","url":null,"abstract":"Introduction: Endoscopic nasal surgery has numerous potential adverse effects, adhesions are at the top of the list. 5-fluorouracil (5-FU), which is an analogue of pyrimidine, is utilized in a wide variety of areas for the purpose of preventing adhesions. In the present investigation, our purpose was to analyze the impact of intra-operative application of 5-flurouracil in the nasal cavity following FESS, as well as to evaluate both subjective and objective outcomes.Materials and methods: Following the acquisition of institutional ethical approval, a testing procedure that was randomized, prospective, and double-blinded was carried out. After the FESS, a cotton swab soaked in 1 mL of 5-flurouracil at 5 mg/mL was inserted in one side of the nasal cavity and a saline-soaked one in the other. Both of these swabs were kept in place for a period of five minutes. Postoperatively, patients were assessed over 6 months duration, wherein, adhesions, discharge, crustation, edema and polypoidal changes were analyzed. Subjective symptoms such as nasal block, nasal discharge and loss of smell were also assessed.Results: At the one-week follow-up, the test group had a significantly higher incidence of adhesions (32% vs. 11.76%, respectively) (p = 0.004) than the control group. Mucosal edema, crusting, polypoidal change and nasal discharge continued to significantly diminish in both groups. Furthermore, improvement in smell perception in the test group at the 20th week post-operatively was statistically significant (p= 0.014).Conclusions: Adhesions are less common in the early postoperative period in individuals who underwent FESS with or without polypectomy when 5-FU is administered topically. There is also an improvement in smell perception with a reduction of mucosal edema, crusting, polypoidal change and nasal discharge enabling better healing.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"37 2","pages":"57-63"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11949431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation Between Indoxyl Sulfate in Chronic Kidney Disease and Olfactory Dysfunction.

Iranian Journal of Otorhinolaryngology Pub Date : 2025-01-01 DOI: 10.22038/ijorl.2024.77737.3632

Irnanda-Warda-Rizki Nasution, Tengku-Siti-Hajar Haryuna, Delfitri Munir, Syafrizal Nasution, Putri-Chairani Eyanoer, Siti Nursiah, Ramlan Sitompul

{"title":"Correlation Between Indoxyl Sulfate in Chronic Kidney Disease and Olfactory Dysfunction.","authors":"Irnanda-Warda-Rizki Nasution, Tengku-Siti-Hajar Haryuna, Delfitri Munir, Syafrizal Nasution, Putri-Chairani Eyanoer, Siti Nursiah, Ramlan Sitompul","doi":"10.22038/ijorl.2024.77737.3632","DOIUrl":"10.22038/ijorl.2024.77737.3632","url":null,"abstract":"Introduction: Olfactory dysfunction is prevalent among individuals with chronic kidney disease (CKD), with prevalence escalating alongside disease severity. The uremic toxin we observed in this study is Indoxyl sulfate (IS), a potent uremic toxin that markedly accumulates in the plasma of patients with chronic insufficiency. Olfactory damage may occur in the setting of neuronal damage due to renal failure.Materials and methods: 27 patients, a total sample in this study with diagnosed chronic kidney disease within stage 5 on regular hemodialysis, were examined for indoxyl sulfate levels in blood plasma and then examined for their olfactory function using the Sniffin' Sticks test. A correlation analysis was conducted between indoxyl sulfate levels and olfactory function test results in patients with CKD.Results: The Pearson correlation test revealed a strong, significant negative correlation between indoxyl sulfate levels and olfactory function (r = -0.613; p = 0.001). Additionally, correlations were found between indoxyl sulfate levels and each component of olfactory function: threshold value (r = -0.408; p = 0.035), discrimination (r = -0.807; p = 0.001), and identification (r = -0.703; p = 0.001).Conclusion: Olfactory function is compromised in individuals with chronic renal disease and correlates with the level of accumulation of the uremic toxin indoxyl sulfate.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"37 1","pages":"19-25"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11750640/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tucker's Reconstructive Laryngectomy: Indications and Functional Outcomes.

Iranian Journal of Otorhinolaryngology Pub Date : 2025-01-01 DOI: 10.22038/ijorl.2024.78978.3660

Malika El Omri, Wassim Kermani, Souhir Chelly, Mouna Bellakhdher, Mohamed Abdelkefi

{"title":"Tucker's Reconstructive Laryngectomy: Indications and Functional Outcomes.","authors":"Malika El Omri, Wassim Kermani, Souhir Chelly, Mouna Bellakhdher, Mohamed Abdelkefi","doi":"10.22038/ijorl.2024.78978.3660","DOIUrl":"10.22038/ijorl.2024.78978.3660","url":null,"abstract":"Introduction: Frontal anterior laryngectomy with epiglottic reconstruction (Tucker's reconstructive surgery) is a technique of partial laryngectomy that has been used by several authors since its introduction in the 80s.The aim of this serie is to specify the indications of this operation and to present the functional and oncological outcomes of our study and those found in the literature.Materials and methods: We report a retrospective study of 65 cases who underwent Tucker's operation by many surgeons at our educational center over a period of 31 years (1988 - 2020).Results: This serie included 62 men (95%) and 3 women (5%), with a mean age of 62,8 years. The cases were classified as follows: 42 patients with T1aN0M0 (65%), 21 patients with T1bN0M0 (32%) and 2 patients with T2N0M0 (3%). Following surgery, the mean time for tracheal cannula extraction was 18,4 days and for nasogastric tube was 14,4 days. Five cases developed aspiration pneumonia. Voice quality was then assessed based on its intensity and intelligibility with 11,7% rated as very good, 53,3% as good, 31,7% as average and 3,3% as poor. There were 4 cases of local recurrence, 2 cases of nodal recurrence, and 2 cases of tumour pursuit. The median survival rate was 7,5 years.Conclusion: The functional and oncological outcomes of Tucker´s reconstructive surgery were generally satisfactory in our patients and are consistent with those reported in the literature. This technique holds an important position of this technique in the therapeutic arsenal for early glottic carcinoma.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"37 1","pages":"3-9"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11750636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laryngeal Frame Involvement as The First Sign of Wegener's Granulomatosis.

Iranian Journal of Otorhinolaryngology Pub Date : 2025-01-01 DOI: 10.22038/ijorl.2024.81617.3746

Davide Burrascano, Barbara Verro, Gaetano Ottoveggio, Ada Maria Florena, Carmelo Saraniti

{"title":"Laryngeal Frame Involvement as The First Sign of Wegener's Granulomatosis.","authors":"Davide Burrascano, Barbara Verro, Gaetano Ottoveggio, Ada Maria Florena, Carmelo Saraniti","doi":"10.22038/ijorl.2024.81617.3746","DOIUrl":"10.22038/ijorl.2024.81617.3746","url":null,"abstract":"Introduction: Granulomatosis with Polyangiitis (GPA), also known as Wegener's Granulomatosis, is an ANCA-associated vasculitis that primarily affects small vessels, leading to necrotizing granulomatous reactions in the airways and small vessels. The etiology remains uncertain.Case report: We report the case of a woman in her 70s, who was previously tracheostomized at another facility and was presented to our attention with glottic-subglottic stenosis. We performed a lysis of glottic synechia and subglottic debulking via transoral laser microsurgery, yielding satisfactory results over the short term. However, a relapse occurred within two months, along with ulcerative lesions on the nasal septum. Biopsies revealed multinucleated giant cells and inflammation suggestive of vasculitis. Based on the histological and clinical features, a diagnosis of vasculitis was considered. Anti-Neutrophil Cytoplasmic Antibodies testing was positive. A rheumatological examination confirmed the hypothesis of Granulomatosis with Polyangiitis. The lack of typical symptoms was the main reason for the delayed diagnosis.Conclusion: Involvement of the subglottic region and the upper portion of the trachea is a rare but severe complication of GPA. The current literature reports only few cases of laryngeal stenosis, with poor prognosis. Histological examinations of biopsied laryngeal tissue showed significant but non-specific inflammation, contributing to the delay in diagnosis. There are still no precise guidelines for the surgical treatment of subglottic stenosis. This case underscores the importance of considering laryngeal involvement in GPA for early diagnosis and timely intervention to prevent serious complications in order to improve patient outcomes.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"37 2","pages":"95-98"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11949434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Junctional Epidermolysis Bullosa Associated Laryngeal Stenosis: A Case Report and Review of Literature. 交界性表皮松解症伴有喉狭窄：病例报告和文献综述。

Iranian Journal of Otorhinolaryngology Pub Date : 2024-09-01 DOI: 10.22038/ijorl.2024.78360.3639

Firyal Balushi, Ziyad Al Harrasi, Maathir Al Farsi, Marwa Al Qurani

引用次数: 0

Life-Threatening Bleeding in Atypical Pleomorphic Adenoma of the Soft Palate. 软腭非典型多形性腺瘤危及生命的出血。

Iranian Journal of Otorhinolaryngology Pub Date : 2024-09-01 DOI: 10.22038/ijorl.2024.75295.3538

Francesca Piccinini, Mario Borgione, Giuseppe Riva, Giancarlo Pecorari

引用次数: 0

Masseteric Vestibular Evoked Myogenic Potentials in Vestibular Neuritis: A Case Series. 前庭神经炎的颚前庭诱发肌源性电位：病例系列。

Iranian Journal of Otorhinolaryngology Pub Date : 2024-09-01 DOI: 10.22038/ijorl.2024.77538.3598

Anjana Rajesh, Anuj Kumar Neupane

引用次数: 0

Submandibular Gland Preservation in Oral Cavity Squamous Cell Carcinomas: Our Analysis at A Tertiary Care Hospital. 口腔鳞状细胞癌中的颌下腺保留：我们对一家三级医院的分析

Iranian Journal of Otorhinolaryngology Pub Date : 2024-09-01 DOI: 10.22038/ijorl.2024.75754.3608

Shahid Rasool, Ayushi Manghani, Shilpam Sharma, Zohda Tayyaba, Sabina Khan, Zarreen Parvez, Neha Dillon, Khaja Naseeruddin, Shamaaila Aftab, Arsal Usman, Hafsa Khan

{"title":"Submandibular Gland Preservation in Oral Cavity Squamous Cell Carcinomas: Our Analysis at A Tertiary Care Hospital.","authors":"Shahid Rasool, Ayushi Manghani, Shilpam Sharma, Zohda Tayyaba, Sabina Khan, Zarreen Parvez, Neha Dillon, Khaja Naseeruddin, Shamaaila Aftab, Arsal Usman, Hafsa Khan","doi":"10.22038/ijorl.2024.75754.3608","DOIUrl":"https://doi.org/10.22038/ijorl.2024.75754.3608","url":null,"abstract":"Introduction: Surgical excision forms the principal treatment of oral cavity squamous cell carcinomas. The comprehensive surgical management consists of Wide Local Excision of the tumor and Neck Dissection with removal of Submandibular gland. The submandibular gland accounts for 70-90 % of unstimulated salivary volume. Its excision as a part of neck dissection has been found to cause high Incidence (21% vs 7%) of postoperative xerostomia. Recent studies have highlighted that the preservation of the SMG is possible and oncologically safe in early-grade OCSCC with N0 neck as the involvement of SMG in such cases is low and its preservation decreases the chances of xerostomia.Materials and methods: 80 subjects were included in the study to estimate the prevalence of metastatic submandibular gland involvement in oral cavity squamous cell carcinomas. The presence of metastasis into the salivary gland was studied and the mechanism/route of involvement was analysed. The comparison was made between the early and advanced tumors for SMG metastasis irrespective of the primary subsite involvement.Results: In the current study low prevalence (6.2 %) of metastasis to SMG was seen. It was seen in high-grade tumors only. None of the early-grade tumors showed any evidence of SMG metastasis. The most common pattern (80%) of glandular involvement was a direct extension from the primary tumor.Conclusions: Our study concludes that SMG preservation neck dissections can be carried out in early-grade OCSCC irrespective of primary tumor site involvement. The advantages of preserving the SMG are multiple. Furthermore, the morbidity is markedly decreased with its preservation without any compromise on oncological safety.","PeriodicalId":14607,"journal":{"name":"Iranian Journal of Otorhinolaryngology","volume":"36 5","pages":"581-586"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11421762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0