Chemistry - An Asian Journal最新文献_第8页

Site-Selective Direct γ-Difunctionalization of Diazoenals: Application to the Synthesis of Enal-Functionalized Allenes and Furans. 重氮烯醛的位点选择性直接 γ-二官能化：应用于合成烯醛官能化的烯烃和呋喃。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-22 DOI: 10.1002/asia.202401081

Jagadeesh Kalepu, Bapurao Sudam Lad, Pratap Kumar Mandal, Vinaykumar Kanchupalli, Durjay Roy, Sreenivas Katukojvala

{"title":"Site-Selective Direct γ-Difunctionalization of Diazoenals: Application to the Synthesis of Enal-Functionalized Allenes and Furans.","authors":"Jagadeesh Kalepu, Bapurao Sudam Lad, Pratap Kumar Mandal, Vinaykumar Kanchupalli, Durjay Roy, Sreenivas Katukojvala","doi":"10.1002/asia.202401081","DOIUrl":"10.1002/asia.202401081","url":null,"abstract":"A new approach for the synthetically important γ-functionalized enals has been developed. The strategy involves rhodium-catalyzed direct C-C & C-S bond forming site-selective γ-difunctionalization of diazoenals with aryl propargyl sulfides via sulfur ylide [2,3] sigmatropic rearrangement, resulting in the highly functionalized γ-allenyl(sulfanyl)enals in excellent yield at ambient temperature. This highly versatile approach constitutes a viable alternative to the remote carbonyl-directed γ-functionalization of unmodified enals which suffer from competitive side reactions. The synthetic utility of the γ-allenyl(sulfanyl)enals was demonstrated by the InCl3-catalyzed cycloisomerization to the trisubstituted furanyl-enals via an unusual 1,4-sulfanyl migration. In addition, an operationally simple and efficient one-pot [3+2] annulation of diazoenals and propargyl sulfides, involving combined γ-difunctionalization and cycloisomerization was successfully developed for the diverse enal-functionalized furans.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202401081"},"PeriodicalIF":3.5,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142491514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Strong Non-Reciprocal Chiroptical Properties in Thin Films of Chiral Alkylthio-Decorated 1,4-Phenylene/Thiophene Dyes. 手性烷基硫代蜕变 1,4-苯/噻吩染料薄膜中的强烈非互易奇光特性。

IF 4.3 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-22 DOI: 10.1002/asia.202401160

Marco Bertuolo, Francesco Zinna, Laura Antonella Aronica, Gennaro Pescitelli, Lorenzo Di Bari, Gianluigi Albano

引用次数: 0

Front Cover: Rational Design of Isolated Tetrahedrally Coordinated Ti(IV) Sites in Zeolite Frameworks for Methyl Oleate Epoxidation (Chem. Asian J. 20/2024) 封面：沸石框架中用于油酸甲酯环氧化的隔离四面体配位Ti(IV)位点的合理设计（Chem.）

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-22 DOI: 10.1002/asia.202482001

Sorasak Klinyod, Krissanapat Yomthong, Ploychanok Iadrat, Pinit Kidkhunthod, Kittisak Choojun, Tawan Sooknoi, Chularat Wattanakit

引用次数: 0

Alkaline Synthesis of Pure Silica ITH Zeolite for Vapor Phase Beckmann Rearrangement of Cyclohexanone Oxime. 碱性合成用于环己酮肟气相贝克曼重排的纯硅 ITH 沸石。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-21 DOI: 10.1002/asia.202401057

Huimin Luan, Tianming Zai, Qinming Wu, Xiangju Meng, Jianping Wu, Weiliao Liu, Na Sheng, Han Wang, Feng-Shou Xiao

引用次数: 0

Dual Au/Ag Catalyzed Regiospecific Intramolecular Hydroacyloxylation and Hydroalkoxylation of Unactivated Geminal-Substituted Olefins. 金/银双重催化未活化双子醛取代烯烃的分子内特异性加氢酰氧基化和加氢烷氧基化。

IF 4.3 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-19 DOI: 10.1002/asia.202401093

Akash D Dhuri, Kiran Kumar Pulukuri

引用次数: 0

Glassy Carbon Electrodes Modified with Ru Nanoparticles Loaded in B-Doped Imidazolium Porous Organic Polymers for Hydrogen Evolution Reaction. 在掺杂 B 的咪唑多孔有机聚合物中添加 Ru 纳米粒子改性的玻璃碳电极，用于氢气进化反应。

IF 4.3 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-18 DOI: 10.1002/asia.202401042

Shasha Ma, Di Chen, Jie Xu, Zhaobin Ye, Jianyong Zhang

引用次数: 0

Strategy in Promoting Visible Light Absorption, Charge Separation, CO₂ Adsorption and Proton Production for Efficient Photocatalytic CO₂ Reduction with H₂O. 促进可见光吸收、电荷分离、二氧化碳吸附和质子产生以实现高效光催化二氧化碳与 H2O 还原的策略。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-17 DOI: 10.1002/asia.202400781

Jia-Fu Zou, Sha Li, Peng Liu, Yiyi Zhao, Tingwei Wang, Yun-Xiang Pan, Xiaoliang Yan

{"title":"Strategy in Promoting Visible Light Absorption, Charge Separation, CO2 Adsorption and Proton Production for Efficient Photocatalytic CO2 Reduction with H2O.","authors":"Jia-Fu Zou, Sha Li, Peng Liu, Yiyi Zhao, Tingwei Wang, Yun-Xiang Pan, Xiaoliang Yan","doi":"10.1002/asia.202400781","DOIUrl":"https://doi.org/10.1002/asia.202400781","url":null,"abstract":"Solar-energy-driven photocatalytic CO2 reduction by H2O to high-valuable carbon-containing chemicals has become one of the greatest concerns in both scientific and industrial communities, due to its potential in solving energy and environmental problems. However, efficiency of photocatalytic CO2 reduction by H2O is still far below the needs of large-scale applications. The reduction efficiency is closely related to ability of photocatalysts in absorbing visible light which is the main part of sunlight (44 %), separating photogenerated electron-hole pairs, adsorbing CO2 and producing protons for reducing CO2. Thus, photocatalysts with enhanced visible light absorption, electron-hole separation, CO2 adsorption and proton production are highly desired. Herein, we aim to provide a picture of recent progresses in improving ability of photocatalysts in visible light absorption, electron-hole separation, CO2 adsorption and proton production, and give an outlook for future researches associated with photocatalytic CO2 reduction by H2O.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202400781"},"PeriodicalIF":3.5,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142454102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Platinum Stabilises a Molten-Globule Conformation of a Small Globular Cytosolic Protein SUMO1. 铂能稳定小球状细胞膜蛋白 SUMO1 的熔融球状构象。

IF 4.3 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-17 DOI: 10.1002/asia.202400971

Suman Tiwari, Sri Rama Koti Ainavarapu

{"title":"Platinum Stabilises a Molten-Globule Conformation of a Small Globular Cytosolic Protein SUMO1.","authors":"Suman Tiwari, Sri Rama Koti Ainavarapu","doi":"10.1002/asia.202400971","DOIUrl":"10.1002/asia.202400971","url":null,"abstract":"Proteins are generally resistant to large conformational changes under physiological conditions. Here, we show that platinum (Pt(II)), which is widely-used metal centre in cancer therapeutic drugs, binds to a cytosolic protein, small ubiquitin-like modifier 1 (SUMO1), under physiological conditions and changes its conformation to a molten globule (MG). Mass spectrometry (ICP-MS) studies confirmed stoichiometric Pt(II) binding to SUMO1. Fluorescence spectroscopy showed Tyr fluorescence quenching and increased ANS binding. Fluorescence assays on Trp-mutants indicated conformational changes and circular dichroism (CD) suggested MG formation upon Pt(II) binding. In contrast, structural homologues of SUMO1 (ubiquitin (Ubq) and SUMO2) showed no conformational changes on Pt(II) titration. Further studies compared the impact of distinct His residues in SUMO1 on Pt(II) binding and protein structure to SUMO2 and Ubq. Experiments at low pH (5.0) implicated His residues interacting with Pt(II), corroborated by the absence of conformational change in the H75L mutant of SUMO1. Pt(II)-His binding in SUMO1 unravels key molecular determinants of Pt(II)-protein interactions and their conformational consequences. SUMO1 with other SUMOylation components are shown to have enhanced expression in several cancers, hence, our study suggests a possible fate of the non-targetability of Pt(II)-based drugs on SUMOylation in cancer cells, upon interaction with SUMO1.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202400971"},"PeriodicalIF":4.3,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142454100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Access to Vinyl Gem-Difluorinated Cyclopropanes Via Photopromoted Palladium-Catalyzed Heck Reaction. 通过光促进钯催化赫克反应获得乙烯基二氟化环丙烷。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-17 DOI: 10.1002/asia.202400775

Bin Li, Qiu-Shi Feng, Jia-Li Yuan, Ying Xia

引用次数: 0

Structural Characteristics and DNA Groove Binding Abilities of Two Zinc-Based Isoreticular MOFs. 两种锌基异质 MOF 的结构特征和 DNA 沟结合能力。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-16 DOI: 10.1002/asia.202400922

Taposi Chatterjee, Priyam Guha, Basudeb Dutta, Samim Khan, Masoom Raza Siddiqui, Saikh M Wabaidur, Mohammad Hedayetullah Mir, Seikh Mafiz Alam

{"title":"Structural Characteristics and DNA Groove Binding Abilities of Two Zinc-Based Isoreticular MOFs.","authors":"Taposi Chatterjee, Priyam Guha, Basudeb Dutta, Samim Khan, Masoom Raza Siddiqui, Saikh M Wabaidur, Mohammad Hedayetullah Mir, Seikh Mafiz Alam","doi":"10.1002/asia.202400922","DOIUrl":"10.1002/asia.202400922","url":null,"abstract":"In this study, we have synthesized two zinc(II)-based metal-organic frameworks (MOFs) designated as [Zn(4-nvp)(bdc)] ⋅ (MeOH) (1) and [Zn2(4-nvp)2(bpdc)2] ⋅ (DMF) (2) [4-nvp=4-(1-naphthylvinyl) pyridine, H2bdc=1,4-benzendicarboxylic acid and H2bpdc=4,4'-biphenyldicarboxylic acid]. Single-crystal X-ray diffraction (SCXRD) of both compounds unveiled an interesting paddle-wheel [Zn2(O2C-C)4] secondary building block (SBB) composed of dinuclear Zn (II) centers and four dicarboxylate groups with a (4,4) square grid topology. These SBBs are interconnected giving rise to an infinite 2D layer architecture. Notably, the grid structure is composed of MeOH molecules in compound 1 and DMF molecules in compound 2, both of them arranged in a free lattice. In both compounds, 3D supramolecular architecture is ultimately formed through the stacking of 2D layers. Since the length of the bpdc ligand is higher than that of the bdc ligand, the solvent-accessible void volume is comparatively higher for compound 2. To corroborate all non-bonded interactions, Hirshfeld analysis was carried out for synthesized compounds. DNA binding application was extensively investigated through docking study. Results indicated that the synthesized compounds have strong affinities towards DNA via DNA groove binding. Henceforth, the synthesized compounds 1 and 2 would open the door for their potential applications as particular protein binders and bioactive substances.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202400922"},"PeriodicalIF":3.5,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142454103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0