Chemistry - An Asian Journal最新文献_第7页

Electron-Deficient Indenofluorene-Based Systems: Multicolor and Visible-To-Near-Infrared (NIR) Electrochromism and OFF-OFF-ON Electrofluorochromism. 缺电子茚芴基系统：多色和可见光-近红外（NIR）电致发光以及关-关-开电致发光。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-29 DOI: 10.1002/asia.202401095

Atul B Nipate, Abhijeet V Kamble, M Rajeswara Rao

{"title":"Electron-Deficient Indenofluorene-Based Systems: Multicolor and Visible-To-Near-Infrared (NIR) Electrochromism and OFF-OFF-ON Electrofluorochromism.","authors":"Atul B Nipate, Abhijeet V Kamble, M Rajeswara Rao","doi":"10.1002/asia.202401095","DOIUrl":"10.1002/asia.202401095","url":null,"abstract":"Multifunctional electrochromic systems with divergent functions are highly sought after but rare and challenging to develop. Here, we report the synthesis and multi-functional electrochromic behaviour (multi-colour modulation, visible-to-near IR absorption switching, and electrofluorochromism) of electron-deficient indenofluorene-based systems. The compounds (IF1-IF5) have been obtained via Knoevenagel condensation of indenofluorenone (IFK) with various nucleophiles (malononitrile, benzylcyanide, dimethyl malonate, methyl cyanoacetate, benzothiazole-2-acetonitrile). IF1-IF5 possess strong colours and absorb in the visible region (λmax=295-388 nm). These compounds are electroactive and exhibit two reversible reduction waves (-0.35--0.88 V and -0.65--1.30 V vs Ag/AgCl), generating radical anion and dianion systems. For the electrochromic studies, upon applying the one-electron reduction potential (-0.35 V vs Ag/AgCl), the absorption maximum of IF1 redshift from 382 nm to 1240 nm (IF1 -⋅), which subsequently blueshifts to 466 & 745 nm (IF1 2-⋅) upon increasing to two-electron reduction potential (-0.65 V vs Ag/AgCl). The color of the solution was switched from green to dark blue and further to light orange. The electrochromic behaviour is highly reversible and cycling. In addition, unlike the non-fluorescent (IF1 and IF1 -⋅), the two-electron reduced system (IF1 2-⋅) is red-emissive (λem=630 nm) due to the combination of radicals leading to the formation of antiaromatic quinoidal π-conjugated system (IF1 2-).","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202401095"},"PeriodicalIF":3.5,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142520498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SELF-ASSEMBLED LIPID NANOPARTICLES FOR KILLING TRIPLE NEGATIVE BREAST CANCER CELLS. 自组装脂质纳米粒子用于杀死三阴性乳腺癌细胞。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-28 DOI: 10.1002/asia.202401049

Wahida Rahaman, Arabinda Chaudhuri

{"title":"SELF-ASSEMBLED LIPID NANOPARTICLES FOR KILLING TRIPLE NEGATIVE BREAST CANCER CELLS.","authors":"Wahida Rahaman, Arabinda Chaudhuri","doi":"10.1002/asia.202401049","DOIUrl":"https://doi.org/10.1002/asia.202401049","url":null,"abstract":"Triple negative breast cancers (TNBCs) lacking estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) on their cell surfaces are highly aggressive, difficult-to-treat and often relapse. Herein, we report on the self-assembled lipid nanoparticles (LNPs) of two new pegylated lipopeptides for killing TNBCs (MDA-MB-231). The pegylated lipopeptides were synthesized by conjugating an n-hexadecyl hydrophobic tail to one end of a (PEG)27 unit the other distal end of which was covalently grafted with two previously reported tumor targeting RGDK- and CGKRK- peptides. The SEM images of the self-assembled LNPs formed upon dissolution of the pegylated lipopeptides in aqueous medium revealed formation of spherical aggregates. The degree of cellular uptake for the self-assembled LNPs formed by the pegylated CGKRK-lipopeptide were found to be significantly higher than that for the self-assembled LNPs formed by the pegylated RGDK-lipopeptide in MCF-7, MDA-MB-231, HEK-293 and HFF cells. Notably, about 60% TNBCs (MDA-MB-231 cells) were killed upon treatment with commercially available potent JAK2 inhibitor (WP 1066) loaded LNPs of the pegylated RGDK-lipopeptide. Contrastingly, the same treatment killed only about 20% non-cancerous HEK-293 cells. The self-assembled pegylated LNPs described herein open the door for undertaking preclinical studies in animal models for TNBCs.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202401049"},"PeriodicalIF":3.5,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142491513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photothermal Catalytic Degradation of VOCs: Mode，System and Application. 光热催化降解挥发性有机化合物：模式、系统和应用。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-28 DOI: 10.1002/asia.202400993

Xiang Bai, Xinyu Qi, Yunchao Liu, Jing Sun, Tingting Shen, Lijun Pan

{"title":"Photothermal Catalytic Degradation of VOCs: Mode，System and Application.","authors":"Xiang Bai, Xinyu Qi, Yunchao Liu, Jing Sun, Tingting Shen, Lijun Pan","doi":"10.1002/asia.202400993","DOIUrl":"https://doi.org/10.1002/asia.202400993","url":null,"abstract":"Human production and living processes emit excessive VOCs into the atmosphere, posing significant threats to both human health and the environment. The photothermal catalytic oxidation process is an organic combination of photocatalysis and thermocatalysis. Utilizing photothermal catalytic degradation of VOCs can achieve better catalytic activity at lower temperatures, resulting in more rapid and thorough degradation of these compounds. Photothermal catalysis has been increasingly applied in the treatment of atmospheric VOCs due to its many advantages. A brief introduction on the three modes of photothermal catalysis is presented. Depending on the main driving force of the reactions, they can be categorized into thermal-assisted photocatalysis (TAPC), photo-assisted thermal catalysis (PATC) and photo-driven thermal catalysis (PDTC). The commonly used catalyst design methods and reactor types for photothermal catalysis are also briefly introduced. This paper then focuses on recent developments in specific applications for photothermal catalytic oxidation of different types of VOCs and their corresponding principles. Finally, the problems and challenges facing VOC degradation through this method are summarized, along with prospects for future research.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202400993"},"PeriodicalIF":3.5,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142491512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing Burning Rate of Ammonium Nitrate by Ammonia Borane: Mechanism from Reactive Molecular Dynamics Simulation. 硼烷氨提高硝酸铵的燃烧速率：反应分子动力学模拟的机理。

IF 4.3 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-25 DOI: 10.1002/asia.202400763

Yin Yu, Jun Jiang, Cai-Chao Ye, Xue-Hai Ju

{"title":"Enhancing Burning Rate of Ammonium Nitrate by Ammonia Borane: Mechanism from Reactive Molecular Dynamics Simulation.","authors":"Yin Yu, Jun Jiang, Cai-Chao Ye, Xue-Hai Ju","doi":"10.1002/asia.202400763","DOIUrl":"10.1002/asia.202400763","url":null,"abstract":"The development of ammonium nitrate (AN)/ammonia borane (AB) as a green propellant is crucial for their applicability in different engines. This study investigates the release patterns of small products, particularly nitrogen-containing molecules, during the initial pyrolysis of AN/AB at low and high pressures using ReaxFF MD simulations. Compared with pure AN, the addition of AB gives the hybrid system enhanced reactivity, leading to faster decomposition and higher energy release. The results show that the consumption of AN in the S13 system (AB with a mass ratio of 12.6 %) is accelerated at 1.47 MPa. NO2 and NO are produced through HNO3 and NO3. At 6.89 MPa, AN exhibits the fastest decomposition rate in the S15 system. The high pressure enhances more reactions of NO with free radicals such as NH and accelerates the release of N2. As the percentage content of AB increases to 15.3 %, more H2O while more NO2 is generated. The effect of AB on the generation of radicals such as H2 and H, is analyzed. AB not only promotes the initial pyrolysis of AN but also accelerates the conversion of intermediates.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202400763"},"PeriodicalIF":4.3,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142491509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elucidating the Photo-Induced Electronic Structure and Mechanisms of ZnAl-Layered Double Hydroxide: A DFT Study. 阐明 ZnAl 层双氢氧化物的光诱导电子结构和机理：DFT 研究。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-25 DOI: 10.1002/asia.202401154

Yi Wang, ZiXian Li, Huijie Liu, Wenjing Dong, Yufei Zhao, Lihong Liu

{"title":"Elucidating the Photo-Induced Electronic Structure and Mechanisms of ZnAl-Layered Double Hydroxide: A DFT Study.","authors":"Yi Wang, ZiXian Li, Huijie Liu, Wenjing Dong, Yufei Zhao, Lihong Liu","doi":"10.1002/asia.202401154","DOIUrl":"10.1002/asia.202401154","url":null,"abstract":"Layered double hydroxides (LDHs) have been regarded as excellent catalysts for a variety of photocatalytic applications including the hydrogen production, carbon dioxide reduction, and nitrogen fixation, et al. The elucidation of the photocatalytic mechanism of LDH-based photocatalysts under light irradiation, especially at the ultraviolet (UV) and deep ultraviolet (DUV) region, at the molecular level has remained elusive. In this study, the photo-induced electronic structure of ZnAl-LDH materials was investigated, and a comprehensive understanding of its underlying mechanism, both in the UV and DUV region, was gained using density functional theory (DFT) calculations. The UV and DUV regions exhibit distinct excitation characteristics, revealing the complex interactions between electrons and holes within the system. The DUV region significantly promotes electron transfer, indicating the potential application of LDH materials as a DUV catalysis material. This study elucidates the electron transfer kinetics in LDHs upon UV and DUV irradiation, thereby offering new perspective for the development of photocatalytic materials under different light region.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202401154"},"PeriodicalIF":3.5,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142491508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

N-Heterocyclic Silylene-Cu(I) Complexes as Efficient Catalysts for Three-Component Coupling Reactions. 作为三组分偶联反应高效催化剂的 N-杂环硅烯-Cu(I)络合物。

IF 4.3 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-23 DOI: 10.1002/asia.202401058

Kashish, Md Jabed Hossain, Shabana Khan

引用次数: 0

Oxidative Stress Mechanism by Gold Compounds: A Close Look at Total ROS Increase and the Inhibition of Antioxidant Enzymes. 金化合物的氧化应激机制：密切关注 ROS 总量的增加和抗氧化酶的抑制作用。

IF 4.3 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-23 DOI: 10.1002/asia.202400792

Jennyfer Castro, Gustavo Clauss, Josielle V Fontes, Laiane S Oliveira, Camilla Abbehausen

{"title":"Oxidative Stress Mechanism by Gold Compounds: A Close Look at Total ROS Increase and the Inhibition of Antioxidant Enzymes.","authors":"Jennyfer Castro, Gustavo Clauss, Josielle V Fontes, Laiane S Oliveira, Camilla Abbehausen","doi":"10.1002/asia.202400792","DOIUrl":"10.1002/asia.202400792","url":null,"abstract":"The antitumor activity of various gold compounds is a promising field of investigation, attracting researchers seeking potential clinical candidates. To advance this research, they explore the complex mechanisms of action of these compounds. Since the discovery of the strong inhibition of thioredoxin reductase by auranofin, the primary mechanism explored has been the inhibition of this enzyme. This inhibition disrupts the redox balance in cells, promoting oxidative stress and triggering cell death. In this review, we analyzed studies from the past decade that measured cellular ROS increase and examined the coordination structures of gold compounds. We also correlate ROS increase with the inhibition of redox-regulating enzymes, thioredoxin reductase, and glutathione reductase, to elucidate the relationship between these cellular effects and chemical structures. Our data compilation reveals that different structures exhibit varying efficacy: some significantly increase ROS production and inhibit thioredoxin reductase or glutathione reductase, while others elevate ROS levels without affecting these target enzymes, suggesting alternative mechanisms of action. This review consolidates critical evidence, enhancing our understanding of the mechanisms by which these gold complexes act and providing valuable insights for developing new therapeutic strategies against tumor cells.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202400792"},"PeriodicalIF":4.3,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142491511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Spacers as a Probe in Variation of Photoluminescence Properties of Mono- and Bi-Nuclear Boron Compounds. 作为单核和双核硼化合物光致发光特性变化探针的间隔物的作用。

IF 4.3 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-23 DOI: 10.1002/asia.202401113

Rahul Kumar Yadav, Darakshan Parveen, Bijan Mondal, Dipak Kumar Roy

{"title":"The Role of Spacers as a Probe in Variation of Photoluminescence Properties of Mono- and Bi-Nuclear Boron Compounds.","authors":"Rahul Kumar Yadav, Darakshan Parveen, Bijan Mondal, Dipak Kumar Roy","doi":"10.1002/asia.202401113","DOIUrl":"10.1002/asia.202401113","url":null,"abstract":"A series of N,O donor-based mono- and binuclear four-coordinated boron complexes were synthesized. Depending on the substitution and spacer, these complexes exhibit intense blue, green and yellow emission in solution states. Notably, the fluorescence quantum yields (ΦF) and fluorescence decay (lifetime, τ) of mononuclear boron complexes (2 a-2 e) were higher than the binuclear boron complexes (2 f-2 k). The lowest lifetime and quantum yield in binuclear boron complexes were due to intramolecular rotation induced non radiative processes. The disulphide spacer-based boron complexes 2 i-2 k showed aggregation-caused quenching in the THF/H2O mixture whereas no other complexes were ACQ responsive. These complexes show large Stokes shift, one of them i. e. 2 e has the highest Stokes shift of 130 nm. Further, the electrochemical study suggests the presence of two redox incidences. Theoretical studies show close corroboration between the TD-DFT computed and experimentally measured absorption maxima as well as DFT (GIAO) calculated and experimentally measured 11B NMR values. This complements the appropriate selection of the theoretical methods to shed light on the electronic transitions in the mono- and binuclear BF2 complexes.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202401113"},"PeriodicalIF":4.3,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142491516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cover Feature: Hybrid Dendrimer Network based on Silsesquioxane and Glycidyl Methacrylate for Enhanced Adsorption of Iodine and Dyes in Environmental Remediation (Chem. Asian J. 20/2024) 封面专题：基于 Silsesquioxane 和甲基丙烯酸缩水甘油酯的混合树枝状聚合物网络在环境修复中增强对碘和染料的吸附（《亚洲化学杂志》20/2024）

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-22 DOI: 10.1002/asia.202482002

Saddam Hussain, Dr. Rungthip Kunthom, Prof. Dr. Hongzhi Liu

引用次数: 0

Cover Feature: A Conjugated Polymer-Based Portable Smartphone Platform for Sensitive and Point-Of-Care Detection of Monoamine Neurotransmitter (Chem. Asian J. 20/2024) 封面专题：基于共轭聚合物的便携式智能手机平台可用于单胺类神经递质的灵敏和定点检测（《亚洲化学杂志》20/2024）

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-22 DOI: 10.1002/asia.202482003

Dr. Nehal Zehra, Dr. Akhtar H. Malik, Retwik Parui, Dr. Sameer Hussain, Prof. Parameswar Krishnan Iyer

引用次数: 0