{"title":"Visible-Light-Driven Synthesis of Pyrrolo[3,4-b]quinolin-1-one Imines Exhibiting Aggregation-Induced Enhanced Emission.","authors":"Chinnagounder Kameshwaran, Fazlur-Rahman Nawaz Khan","doi":"10.1002/asia.202500770","DOIUrl":"https://doi.org/10.1002/asia.202500770","url":null,"abstract":"<p><p>In recent years, visible light-mediated transformations have gained significant attention. In this work, we report the synthesis of N-substituted 2,3-dihydro-1H-pyrrolo[3,4-b]quinolin-1-ones via a one-pot strategy involving C(sp<sup>3</sup>)-H functionalization, cyclization, and condensation to form the corresponding imines under visible-light conditions. Furthermore, the imines exhibited Aggregation-Induced Enhanced Emission (AIEE) properties and favorable photophysical response toward metal ions. Subsequent metal-free aerobic oxidation of these imines in the presence of a peroxide medium afforded the corresponding amides. The synthetic utility of this protocol was further demonstrated through post-functionalization of the products and gram-scale synthesis.</p>","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e00770"},"PeriodicalIF":3.3,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145068751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"On the Rise of Slurry Electrolysis for Energy Applications","authors":"Jingjing Xiong, Guanwu Lian, Prof. Zhongxin Chen","doi":"10.1002/asia.202500851","DOIUrl":"10.1002/asia.202500851","url":null,"abstract":"<p>Slurry electrolysis represents a paradigm shift in diverse electrochemical applications by replacing conventional fixed electrodes with flowable suspensions of electrochemically active particles for scalable energy conversion and storage. In this perspective, we will detail the recent advances of slurry electrolysis in electrocatalysis, semi-solid flow batteries, and flow-electrode capacitive deionization, featuring the fundamental role of the formation of the electro-percolation network in charge transport in these slurry systems. Mechanistic insights into the dynamic evolution of flowable suspension are provided via advanced characterization techniques, including operando EIS, computational fluid dynamics calculations, and in situ imaging. Finally, we will provide a forward-looking perspective in tackling the challenges in electrochemical side reactions and slurry instability for their practical applications.</p>","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":"20 19","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://aces.onlinelibrary.wiley.com/doi/epdf/10.1002/asia.202500851","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145062995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Synthesis and Characterization of Electron-Deficient Perfluorinated Tetrathia[8]Circulene via Sequential Coupling Reactions.","authors":"Toma Tanaka, Hiroyasu Murase, Mio Shimogaki, Osamu Iwanaga, Hiroshi Shinokubo, Yoshihiro Miyake","doi":"10.1002/asia.202500806","DOIUrl":"https://doi.org/10.1002/asia.202500806","url":null,"abstract":"<p><p>Tetrathia[8]circulene is a heteroaromatic framework consisting of an eight-membered ring fused with four thiophene and four benzene units, whose electronic properties are highly tunable by peripheral substituents. Herein, we report the synthesis of a perfluorinated tetrathia[8]circulene bearing hexafluorocyclopentene rings via sequential Suzuki-Miyaura and C─H/C─Cl coupling reactions. Single-crystal X-ray diffraction analysis revealed a highly planar π-conjugated core with dense F···F contacts, leading to a two-dimensional layered and one-dimensional columnar packing structure. UV-vis absorption spectroscopy and cyclic voltammetry demonstrated that the electron-withdrawing hexafluorocyclopentene units substantially lower the LUMO energy level, resulting in a reduced HOMO-LUMO gap and enhanced electron-accepting character. Density functional theory calculations further supported these findings by correlating the perfluoroalkyl annulation with frontier orbital stabilization and excited-state properties.</p>","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e00806"},"PeriodicalIF":3.3,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145063001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmed F Saber, Munzir H Suliman, Ali M Tayeb, Mohamed Essalhi, Mohamed Hammad Elsayed, Amr Sabbah, Kuei-Hsien Chen, Mahmoud M Abdelnaby
{"title":"Engineering of Copper-Based Nitrogen-Rich Covalent Triazine Frameworks (Cu@CTFs) as Highly Efficient Electrocatalysts for Carbon Dioxide Reduction.","authors":"Ahmed F Saber, Munzir H Suliman, Ali M Tayeb, Mohamed Essalhi, Mohamed Hammad Elsayed, Amr Sabbah, Kuei-Hsien Chen, Mahmoud M Abdelnaby","doi":"10.1002/asia.70292","DOIUrl":"https://doi.org/10.1002/asia.70292","url":null,"abstract":"<p><p>In this study, we employed a simple and efficient method to synthesize two porous covalent triazine frameworks (CTFs) using a cyanuric chloride core with both 1,4-diaminobenzene and 1,1'-biphenyl-4,4'-diamine, which were subsequently embedded with copper acetate, giving Cu@CTF electrocatalysts. The composite materials were comprehensively characterized, and their performance in the electrochemical CO<sub>2</sub> reduction reaction (CO<sub>2</sub>RR) was systematically evaluated. The Cu@CTFs exhibited significant enhancements in CO<sub>2</sub>RR performance compared to their unmodified counterparts. The as-synthesized Cu@CC-BP-CTF electrocatalyst possessed exceptional catalytic efficiency due to its highly porous structure and great surface area. At a voltage of 1.6 V versus RHE, it achieved a maximum CO Faradaic efficiency of 39%. In addition, the activity of this system was characterized by a partial current density of around 85.8 mAcm<sup>-2</sup> in a flow-cell configuration. Furthermore, this catalyst demonstrated remarkable stability over 10 h, highlighting its significant potential for real-world utilization in CO<sub>2</sub>RR. The Cu@CC-BP-CTF electrode exhibited superior CO<sub>2</sub>RR activity, higher mass activity, and improved charge transfer rates incomparable to the unmodified counterpart. These findings highlight the crucial role of copper in modifying the surface properties of electrocatalysts, providing valuable insights into the design strategies for advanced materials with enhanced performance in electrochemical applications.</p>","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e70292"},"PeriodicalIF":3.3,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145063054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Indrajit Karmakar, Goutam Brahmachari, Chin-Fa Lee
{"title":"Electrochemistry-Driven Seleno-Functionalization of Diverse Organic Scaffolds: A Recent Update.","authors":"Indrajit Karmakar, Goutam Brahmachari, Chin-Fa Lee","doi":"10.1002/asia.202500817","DOIUrl":"https://doi.org/10.1002/asia.202500817","url":null,"abstract":"<p><p>Organoselenium compounds have captivated researchers owing to their multifaceted roles in biological systems, medicinal chemistry, materials science, and advanced organic synthesis. This growing interest has spurred the development of practical and sustainable methodologies for constructing carbon-selenium (C─Se) bonds, transforming simple building blocks into architecturally complex molecules. Among these, electro-organic synthesis has emerged as a powerful, green technology for forging such bonds with high efficiency. Electrochemical seleno-functionalization offers a cost-effective and environmentally benign route to valuable selenylated products. This review captures the latest advancements in the field, examining reaction scope, mechanistic pathways, and current challenges. This review summarizes recent progress and highlights emerging perspectives in the electrochemical seleno-functionalization of organic molecules, focusing on studies published during 2018 to mid-2025.</p>","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e00817"},"PeriodicalIF":3.3,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145062992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Md Monjorul Islam, Arshad Hussain, Najia Tahsin Kumkum, Sheikh Jakia Nur Oishee, M Nasiruzzaman Shaikh, Nadeem Baig, Md Abdul Aziz, A J Saleh Ahammad
{"title":"Recent Advances in Polyacrylonitrile-Based Separators for Aqueous Zinc-Ion Batteries.","authors":"Md Monjorul Islam, Arshad Hussain, Najia Tahsin Kumkum, Sheikh Jakia Nur Oishee, M Nasiruzzaman Shaikh, Nadeem Baig, Md Abdul Aziz, A J Saleh Ahammad","doi":"10.1002/asia.202500810","DOIUrl":"https://doi.org/10.1002/asia.202500810","url":null,"abstract":"<p><p>The electrical energy enhances the proliferation of electronic devices in the modern era. Typically, most electronic devices run on a lithium-ion battery (LIB). However, safety issues prompt researchers to consider alternatives, and the aqueous zinc-ion battery (AZIB) emerged as an alternative with higher merits. One of the fundamental segments of the AZIB is the separator that provides ion transportation on both sides of the battery while deterring direct contact between the cathode and anode. For AZIBs, glass fiber (GF) is the most conventional separator considering their availability and cost-effectiveness, suffering from various hurdles, for instance, dendrite formation, which is the primary concern, causing an explosion during battery operation, and the low mechanical strength. Conversely, the polyacrylonitrile (PAN) prevents dendrite formation through the electrostatic interaction, deposition along the (002) plane, 3D diffusion, and selective zinc ion permeation, and offers high cyclability. We segment this paper into four parts: first, it discusses the basic features of the ideal separator; second, the preparation methods of the separator; third, a critical overview of the PAN-based separator for AZIB, especially the dendrite mitigation strategies; and finally, it provides the future directions and strategies for advance PAN-based separator design.</p>","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e00810"},"PeriodicalIF":3.3,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145063057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Metallic Nanozymes: From Catalytic Mechanisms to Biomedical Therapeutics and Flexible Wearable Integration","authors":"Zeeshan Ahmad, Isha Ishfaq, Jiajia Li, Ankush Sheoran, Xiaohan Guo, Qingyu He, Zhixuan Chen, Wenjing Liu, Faisal Saleem","doi":"10.1002/asia.202500814","DOIUrl":"10.1002/asia.202500814","url":null,"abstract":"<p>Nanozymes, a groundbreaking class of artificial enzymes, have been recognized as one of the top ten emerging technologies in chemistry by the International Union of Pure and Applied Chemistry in 2022, which has brought biomedical applications and wearable electronic devices to a different stage due to their enzyme-like catalytic activities. These synthetic catalysts effectively overcome the limitations associated with natural enzymes, including their inherent instability and high costs, while simultaneously providing adjustable redox activity and multifunctional capabilities. In this review paper, we summarize the catalytic mechanisms of metallic nanozymes, their biomedical applications, including biosensing, antimicrobial therapies, tumor therapies, and anti-inflammatory strategies, as well as their integration into advanced wearable electronic devices. Finally, we discuss future research directions to guide the progress of next-generation nanozymes for precision medicine and smart diagnostics. This review could provide a pathway for interdisciplinary metallic nanozymes advancements, highlighting their potential to revolutionize personalized medicine and diagnostics, while addressing unsolved challenges in biosafety and scalability.</p>","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":"20 20","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145038909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Simple Water-Soluble TREN-1,8-aphthalimide Fluorescent \"Turn-On\" PET Sensor for Selective and Reversible Detection of Cu(II) Ion and Application in Cellular Imaging.","authors":"Mannanthara Kunhumon Noushija, Sweata Hanson, Deivasigamani Umadevi, Nandita Mishra, Sankarasekaran Shanmugaraju","doi":"10.1002/asia.70309","DOIUrl":"https://doi.org/10.1002/asia.70309","url":null,"abstract":"<p><p>A new water-soluble 1,8-naphthalimide fluorophore, TREN-Nap, is synthesized in quantitative yield through a one-pot imidation reaction between 1,8-naphthalic anhydride and tris(2-aminoethyl)amine (TREN). TREN-Nap is then employed as a fluorescent \"turn-on\" chemosensor for detecting Cu(II) ions in water. The fluorescence titration studies revealed remarkable selectivity and reversible binding affinity of TREN-Nap toward Cu(II) ions, with significant enhancement (turn-on) in fluorescence emission intensity and sensitivity at the micromolar level (0.74 µM, 0.24 ppm). Notably, similar titration studies with other commonly interfering metal cations such as Zn(II), Mg(II), Cd(II), Ni(II), Co(II), Ba(II), Al(III), Pb(II), and Ca(II) caused almost negligible changes in the emission intensity, indicating their weak binding with TREN-Nap. Moreover, TREN-Nap displayed impressive sensing capability for Cu(II) ions even in real water samples. TREN-Nap is further employed as a bioimaging agent in breast cancer (MDA-MB-231) and lung epithelial (L929) cells. These results affirm that TREN-Nap is an excellent fluorescent \"turn-on\" sensor for Cu(II) ion detection in water and biological media.</p>","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e70309"},"PeriodicalIF":3.3,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145038916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shakira Allah Baksh, Ata-ur-Rehman, Safyan Akram Khan, Shahid Ali, Majad Khan, Dr. Muhammad Mansha, Faizah Altaf, Dr. Muhammad Nawaz Tahir
{"title":"Sustainable Nafion–Cellulose Composite Membrane: Role of Biomass-Derived Cellulose Loading in Suppression of Polysulfide Shuttling for Redox Flow Batteries","authors":"Shakira Allah Baksh, Ata-ur-Rehman, Safyan Akram Khan, Shahid Ali, Majad Khan, Dr. Muhammad Mansha, Faizah Altaf, Dr. Muhammad Nawaz Tahir","doi":"10.1002/asia.202500679","DOIUrl":"10.1002/asia.202500679","url":null,"abstract":"<p>The cross-shuttling of polysulfide ions in bromine/polysulfide-based redox flow batteries (RFBs) is one of the major challenges that hinder their overall performance. Herein, we utilized cellulose extracted from waste date palm trees (DPT) and Nafion to fabricate an in-house membrane that contributes to mitigating this problem. A series of Nafion membranes with cellulose ratios of 5, 10, 20, and 30 wt% were fabricated and labeled CNF5, CNF10, CNF20, and CNF30, respectively. The CNF20 displayed promising thickness (∼77 µm) and mechanical stability, and as a result, it was investigated further and compared with the commercial Nafion 117 membrane. CNF20 exhibited an ion exchange capacity of 1.35 meq/g, water uptake of 39% and ionic conductivity of 0.090 S/cm. Both membranes exhibited a charge capacity of approximately 555.5 mAh/L. However, CNF20 retained 99.9% of its capacity, as compared to 93.7% for Nafion 117, after 100 cycles. The charge capacity decay and discharge capacity decay for CNF20 were 18 times and 120.6 times lower, respectively, than for the Nafion 117 membrane. The CNF20 showed energy efficiency of 31.3% whereas Nafion 117 exhibited 23.2% over 100 cycles. The cost analysis for CNF20 resulted in a 57.7% reduction as compared to the commercial price of Nafion 117. These results position CNF20 as a cost-effective, sustainable, and eco-friendly alternative compared to a membrane composed solely of Nafion 117.</p>","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":"20 19","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145032554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Donor-extended meso-Disubstituted Dipyrromethane-Based Dipodal Ligands and Their Metal Complexes: An Overview.","authors":"Monalisa Giri, Satabdi Roy, Tapas Guchhait","doi":"10.1002/asia.70256","DOIUrl":"https://doi.org/10.1002/asia.70256","url":null,"abstract":"<p><p>The meso-disubstituted dipyrromethanes are an important class of ligand system which coordinate metal-ions across the periodic table as they feature two σ-donor anionic pyrrolic-N-atoms and offer pyrrole-π-electrons to the metal centres. They have the active 1,9-positions for preparing their variants that may contain additional donor atoms in the side arms. The introduction of the arms to the dipyrromethane moieties not only make them polyfunctional but also enhances flexibility of the system. In this review article, we highlight the syntheses and metal-ion coordination of various donor-extended meso-disubstituted dipyrromethane-based ligands that include the scaffolds decorated with diamine, diimine, bis-azo, diphosphine, or bis-pyrazole functions on both sides. The resulting NNNN and PNNP types of tetradentate dipodal ligands yield a large number of transition or alkali metal complexes with attractive structural and coordination properties, expressing the main focus of this article. We also emphasize the structural variations of the complexes dictated by the steric-bulk of the substituents at the meso-position or at the termini of the dipods. In addition, certain metal complexes bearing the extended ligand(s) participate in distinct catalytic transformations and also show interesting magnetic behaviors that are minutely discussed. Finally, a few hints of research endeavours are outlined for future purview.</p>","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e70256"},"PeriodicalIF":3.3,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145032575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}