Chemistry - An Asian Journal最新文献_第6页

Organometallic Ru(III) Catalysts for α-Alkylation of Carbonyl Compounds using Alcohols: Mechanistic Insights via Detection of Key Intermediates. 使用醇对羰基化合物进行 α-烷基化反应的有机金属 Ru(III) 催化剂：通过检测关键中间体揭示机理。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-11-01 DOI: 10.1002/asia.202400811

Sain Singh, Rajat Saini, Virendra Kumar Chaudhary, Kaushik Ghosh

{"title":"Organometallic Ru(III) Catalysts for α-Alkylation of Carbonyl Compounds using Alcohols: Mechanistic Insights via Detection of Key Intermediates.","authors":"Sain Singh, Rajat Saini, Virendra Kumar Chaudhary, Kaushik Ghosh","doi":"10.1002/asia.202400811","DOIUrl":"https://doi.org/10.1002/asia.202400811","url":null,"abstract":"Three novel cyclometalated ruthenium complexes ([Ru.L(9)] [Ru.L(10)] and [Ru.L(11)]) featuring azo functionalities were synthesized and characterized using a variety of spectroscopic techniques, namely FT-IR, electronic absorption spectroscopy, and ESI-MS. Representative solid-state structures of the acquired complexes were determined through X-ray crystallography. These complexes were evidenced to be efficient catalysts for the synthesis of various α-alkylated compounds utilizing simple acetophenone derivatives with easily affordable and economically viable alcohols, which were isolated and characterized via 1H and 13C NMR spectroscopy. The optimum reaction conditions were found by employing toluene as solvent, potassium tert-butoxide as base at 115 oC temperature utilizing 0.8 mol% of catalyst [Ru.L(10)]. The yield of the desired compounds found to be in the range of 83 - 97%. Additionally, mass spectrometry provided insights into the in-situ generated ruthenium hydride and ruthenium alkoxy intermediates, shedding light on the catalytic mechanism.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202400811"},"PeriodicalIF":3.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142556517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Esterase-Responsive Self-Immolative Prodrugs for the Sustained Delivery of the Anticancer Drug 5-Fluorouracil with Turn-On Fluorescence. 用于持续递送具有开启荧光的抗癌药物 5-氟尿嘧啶的酯酶响应型自巯基原药。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-11-01 DOI: 10.1002/asia.202400846

Md Badirujjaman, Rajkumar P Thummer, Krishna P Bhabak

{"title":"Esterase-Responsive Self-Immolative Prodrugs for the Sustained Delivery of the Anticancer Drug 5-Fluorouracil with Turn-On Fluorescence.","authors":"Md Badirujjaman, Rajkumar P Thummer, Krishna P Bhabak","doi":"10.1002/asia.202400846","DOIUrl":"10.1002/asia.202400846","url":null,"abstract":"Stimuli-responsive prodrugs of anticancer drugs are advantageous for the selective delivery of drugs to cancer cells with minimized off-target side effects. In the present study, esterase-activatable fluorogenic prodrugs of the chemotherapeutic drug 5-fluorouracil (5-FU) have been rationally designed and synthesized using multi-step organic synthesis. While 5-FU was connected directly with the fluorophore via a C-N bond in the prodrug BJ-50, an additional self-immolative benzylic spacer with a carbonate linker was incorporated in the prodrug BJ-92. Although absorption and emission spectroscopic studies revealed the activation of both the prodrugs by porcine liver esterase (PLE), reverse-phase HPLC studies confirmed the inability of BJ-50 to release the active drug 5-FU. In contrast, a sustained release of 5-FU and Cou-OH was observed from BJ-92 in the presence of PLE. The endogenous esterase-mediated activation of the prodrug BJ-92 was validated by the turn-on fluorescence in A549 cells and the anti-proliferative activities in A549, and HEK-293 cells. Modulation of the expression of a few cancer marker proteins by BJ-92 and 5-FU was studied to evaluate their anticancer activities. As esterases are overexpressed in cancer cells, the prodrug in the present study would be helpful in selectively delivering 5-FU to cancer cells with reduced off-target side-effects.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202400846"},"PeriodicalIF":3.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142556516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polymer Electrolytes with High Ionic Conductivities at Freezing Temperature for Aqueous Hybrid Batteries. 用于水基混合电池的冻结温度下具有高离子电导率的聚合物电解质。

IF 4.3 3区化学

Chemistry - An Asian Journal Pub Date : 2024-11-01 DOI: 10.1002/asia.202401110

Zhongdong Tian, Yuan Gao, Peishu Tian, Silong Tian, Fengwei Shi, Jun Mei

{"title":"Polymer Electrolytes with High Ionic Conductivities at Freezing Temperature for Aqueous Hybrid Batteries.","authors":"Zhongdong Tian, Yuan Gao, Peishu Tian, Silong Tian, Fengwei Shi, Jun Mei","doi":"10.1002/asia.202401110","DOIUrl":"10.1002/asia.202401110","url":null,"abstract":"Rechargeable and flexible aqueous batteries (ABs) have emerged as one of promising energy devices which is primarily due to the safety, environmental friendliness and economic efficiency. However, because of the freezing behavior of aqueous electrolytes, most ABs possess poor performance when the working temperature drops below zero. To solve this problem, a gel polymer electrolyte (GPE) with high ionic conductivity (IC) and frost-resistance is designed for aqueous Zn-Li hybrid batteries by a biomass-based polymers complex consisting of carboxyl modified sodium alginate (SA) and zwitterionic betaine (BA). Introducing iminodiacetic acid to enrich -COOH groups along the SA main chains could improve IC of the prepared GPEs to 41.27 and 20.96 mS cm-1 at 20 and -20 °C, respectively. At -20 °C, the discharge capacity of the resultant cell is two times higher than that of the liquid electrolyte-based cell, and the cell presents a capacity retention of 91.6 % after 300 charge/discharge cycles at 1 C. This proposed strategy greatly improve the IC of GPEs at freezing temperature, which is expected to broaden the practical application of GPEs in wide range of temperature.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202401110"},"PeriodicalIF":4.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142563338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Natural Surface Frustrated Lewis Pairs: The Concept and Beyond. 自然表面受挫路易斯对：概念及其他

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-31 DOI: 10.1002/asia.202401155

Xi-Yang Yu, Xue Su, Meng-Jia Xi, Zheng-Qing Huang, Chun-Ran Chang

引用次数: 0

A Fluorescent Probe with Large Stokes Shift Based on Benzothiadiazole Scaffolds for Selective Detection of Hg²⁺ in Lysosomes and Its Application in Biological Imaging. 一种基于苯并噻二唑支架的具有大斯托克斯偏移的荧光探针，用于选择性检测溶酶体中的 Hg2+ 及其在生物成像中的应用。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-31 DOI: 10.1002/asia.202401067

Lin Wang, Ning Zhang, Yuan He, Jian-Yong Wang

引用次数: 0

In Situ Catalyzed Growth of Carbon Nanotube with Asphalt Cladding as a Bicarbon Synergistic Framework of Silicon Anodes for Lithium-ion Batteries. 原位催化碳纳米管与沥青包层的生长，作为锂离子电池硅阳极的双碳协同框架。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-30 DOI: 10.1002/asia.202400838

Yiming Liu, Jianzheng Duan, Pengfei Chen, Peihua Li, Wanggang Zhang, Xiaohong Li, Jian Wang

{"title":"In Situ Catalyzed Growth of Carbon Nanotube with Asphalt Cladding as a Bicarbon Synergistic Framework of Silicon Anodes for Lithium-ion Batteries.","authors":"Yiming Liu, Jianzheng Duan, Pengfei Chen, Peihua Li, Wanggang Zhang, Xiaohong Li, Jian Wang","doi":"10.1002/asia.202400838","DOIUrl":"10.1002/asia.202400838","url":null,"abstract":"Silicon, as the most promising advanced anode material for lithium-ion batteries, faces challenges in large-scale industrial production due to the significant volume expansion effect. In this investigation, Si/CNTs/C composite materials were effectively produced through high-temperature carbonization utilizing asphalt, silicon, hexahydrate ferric chloride, and melamine as primary elements. The distinctive dual-carbon framework of asphalt-derived carbon and carbon nanotubes alleviates the volume expansion of silicon, thereby stabilizing the composite material's structure. Testing the electrochemical performance reveals that the Si/CNTs/C composite material exhibits a reversible specific capacity of 1187 mAh g-1 with a capacity retention rate of 92.6 % after 150 cycles at a current density of 0.2 A g-1. Even after 500 cycles at a current density of 1 A g-1, it sustains a specific capacity of 879.4 mAh g-1 with a capacity retention rate of 87.9 %, showcasing outstanding electrochemical performance.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202400838"},"PeriodicalIF":3.5,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142542243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design and Development of Infiltration Resins: From Base Monomer Structure to Resin Properties. 渗透树脂的设计与开发：从单体结构到树脂特性。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-30 DOI: 10.1002/asia.202401157

Shuo Yang, Ting Zhao, Xiaoqiu Liu, Haibo Zhang, Bo Yang, Zheng Chen

{"title":"Design and Development of Infiltration Resins: From Base Monomer Structure to Resin Properties.","authors":"Shuo Yang, Ting Zhao, Xiaoqiu Liu, Haibo Zhang, Bo Yang, Zheng Chen","doi":"10.1002/asia.202401157","DOIUrl":"10.1002/asia.202401157","url":null,"abstract":"The resin infiltration concept is one of the most widely used minimally invasive restorative techniques in restorative dentistry with the most outstanding therapeutic effect, and it is also one of the key research directions in restorative dentistry. \"Infiltration resin\" is the specialty restorative material for the technology, which is the key factor to success. The specialized restorative material is commonly known as \"infiltrant/infiltration resins\" \"resins infiltrant\" \"infiltrant\" or \"resins,\" which will be consistently referred to as \"infiltration resins\" throughout the article. The paper aims to provide a comprehensive overview of infiltration resins by introducing the development of their therapeutic mechanisms, basic components, current challenges, and future trends, Based on existing literature, we analyze and compare how changes in the base monomer's structure and ratio affect the effectiveness of infiltration resins, from the material's structure-effective relationship. After compiling the information, the existing solution strategies have been listed to offer substantial support and guidance for future research endeavors.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202401157"},"PeriodicalIF":3.5,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142542242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Low-valent Main-group Catalysis Under Ambient Conditions Using a Germylene Cation*. 在环境条件下使用亚甲基阳离子进行低价主族催化*。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-30 DOI: 10.1002/asia.202400692

Hemant Kumar, Pritam Mahawar, Purva Dua, Vivek Kumar Singh, Pratima Shukla, Prakash Chandra Joshi, Gopalan Rajaraman, Selvarajan Nagendran

引用次数: 0

Visible Light-Driven Metal- and Photocatalyst-Free Synthesis of β-Trifluoromethylated Enamines via Trifluoromethyl Thianthrenium Salts. 通过三氟甲基噻蒽盐以可见光驱动无金属和光催化剂合成β-三氟甲基化烯胺。

IF 4.3 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-29 DOI: 10.1002/asia.202401129

Liang Jiang, Yisong Tang, Shaxuan Li, Xing Peng, Rim Saffar Andaloussi, Xiao Yun Chen

引用次数: 0

3D Graphene-like Carbon Structures from Poly(Acrylic Acid): A Novel Synthetic Route. 聚丙烯酸三维类石墨烯碳结构：新型合成路线。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-10-29 DOI: 10.1002/asia.202400832

Ana L A Simões, Lílian A de Carvalho, Rochel M Lago, Célia M Ronconi, Sara S Vieira, Maria H Araujo

{"title":"3D Graphene-like Carbon Structures from Poly(Acrylic Acid): A Novel Synthetic Route.","authors":"Ana L A Simões, Lílian A de Carvalho, Rochel M Lago, Célia M Ronconi, Sara S Vieira, Maria H Araujo","doi":"10.1002/asia.202400832","DOIUrl":"https://doi.org/10.1002/asia.202400832","url":null,"abstract":"Emerging contaminants, such as the hormone 17α-ethynylestradiol (EE), in aquatic environments pose a serious risk to both human and environmental health, making efficient removal essential. This study evaluated the effectiveness of three-dimensional porous carbon structures derived from poly(acrylic acid) (PAAc, Carbopol 990) as adsorbents for removing EE from aqueous solutions. Activated carbon materials were prepared using varying ratios of KOH as an activating agent (PAAc:KOH; 1:0 AAC, 1:1 AC1, 1:2 AC2, and 1:3 AC3). Adsorption tests were conducted by adding 10 mg of the adsorbent to 40 mL of an EE solution (100 ppm, 20% acetonitrile in water). Analyses including TGA, XRD, and Raman spectroscopy were performed to evaluate the materials' structural properties and adsorption capacities. Among the materials, AC3 exhibited the highest adsorption capacity for EE (238 mg g-1), followed by AC2 (153 mg g-1) and AC1 (82 mg g-1). The superior efficiency of AC3 can be attributed to its larger surface area and pore volume, enabling greater interaction with EE molecules. These materials demonstrated higher adsorption capacities compared to commercial activated carbons and single-walled carbon nanotubes. This work opens new possibilities for developing efficient adsorbents, contributing to more effective and sustainable solutions for water purification and environmental protection.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202400832"},"PeriodicalIF":3.5,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142542241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0