Italian Journal of Dermatology and Venereology最新文献

{"title":"Comparing the clinical response and patient satisfaction of foam versus cream calcipotriol-betamethasone dipropionate treatment of localized plaque psoriasis.","authors":"Pietro Scribani Rossi, Nicoletta Bernardini, Giuseppe Gemma, Giuseppe Rizzuto, Elena Zappia, Simone Amato, Antonella Tammaro, Valeria Falcomatà, Alessia Chiarello, Pietro P Cozza, Luigi Bennardo, Eugenio Provenzano, Nevena Skroza, Concetta Potenza, Steven P Nisticò, Giovanni Pellacani, Annunziata Dattola","doi":"10.23736/S2784-8671.26.08462-8","DOIUrl":"10.23736/S2784-8671.26.08462-8","url":null,"abstract":"<p><strong>Background: </strong>Calcipotriol-betamethasone dipropionate (Ca/BDP) is an effective topical treatment for localized plaque psoriasis. It is available in various formulations, including foam and cream; the differences in patient satisfaction and tolerability may impact treatment adherence and, consequently, clinical outcomes.</p><p><strong>Methods: </strong>This study seeks to compare the clinical response and patient satisfaction between foam and cream formulations of Ca/BDP in the treatment of localized plaque psoriasis via a retrospective, multicenter observational study conducted on 108 patients with localized plaque psoriasis. Patients completed a standardized questionnaire assessing itch control, tolerability, and pleasantness (scored 0-3). Clinical response was assessed through PASI-based evaluation.</p><p><strong>Results: </strong>No significant differences were observed in age (P=0.085), sex distribution (P=0.055), or clinical response (P=0.113) between the two groups. However, cream was associated with significantly greater itch control (P=0.008), tolerability (P=0.011), and pleasantness (P<0.001) compared to foam. While clinical efficacy was comparable between formulations, the cream version of Ca/BDP was associated with higher patient satisfaction and better itch control.</p><p><strong>Conclusions: </strong>These findings suggest that patient preference and formulation tolerability should be considered when prescribing topical therapies, as they may influence treatment adherence and long-term outcomes.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"367-371"},"PeriodicalIF":2.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147638834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Organization of skin ulcer outpatient clinics in Italy: results from a survey of the Study Group on Ulcers of the Italian Society of Dermatology and Venereology.","authors":"Andrea Michelerio, Linda Tognetti, Valentina Dini, Marco Romanelli, Paola Monari, Maria C Collina, Agata Janowska, Giammarco Granieri, Salvatore Panduri, Maria Erasti, Giulia Galuccio, Pietro Rubegni, Maria A Pilla, Alberico Motolese, Marco Spadafora, Caterina Longo, Annunziata Dattola, Antonio G Richetta, Giovanni Pellacani, Victor D Mandel, Andrea Conti, Alfonso Motolese, Andrea Marani, Antonella Frassetto, Andrea Megna, Alessandra G Condorelli, Luca Contu, Flavia Persechino, Alessandra Michelucci, Flavia Manzo Margiotta, Bianca Cei, Serena Messinese, Federico Garbarino, Luca Ambrosio, Federica Trovato, Emanuele Scala, Carlo Tomasini, Camilla Vassallo, Alessia Paganelli","doi":"10.23736/S2784-8671.26.08393-3","DOIUrl":"10.23736/S2784-8671.26.08393-3","url":null,"abstract":"<p><strong>Background: </strong>Chronic skin ulcers represent a significant burden for healthcare systems due to their high prevalence, prolonged healing times and recurrence rates. Despite their impact, the organization and resources of outpatient ulcer clinics remain poorly characterized worldwide. The aim of this study was to evaluate the organization of outpatient clinics for chronic skin ulcers in the Italian dermatological setting.</p><p><strong>Methods: </strong>A survey was distributed to all the members of the Study Group on Cutaneous Vascular Diseases and Skin Ulcers of the Italian Society of Dermatology and Venereology. The survey collected data on outpatient service organization, multidisciplinary involvement, nursing support, services provided, and patient volume.</p><p><strong>Results: </strong>Thirty-nine clinicians from 10 centers participated. Nine centers reported dedicated outpatient dermatologic ulcer clinics, with approximately two thirds (6/9) integrating multidisciplinary approaches. The services operate an average of three days per week and manage approximately 13-14 patients per day (mean:13.5). Universally available services at ulcer outpatient clinics include dermatological consultation, wound care (curettage, simple dressings, advanced dressings) and specialized nursing staff. Further widely performed diagnostic and therapeutic procedures include microbiological swabs, skin biopsy and vascular consultation. More advanced services are available only in selected centers.</p><p><strong>Conclusions: </strong>This study highlights significant variations in the organization and resources of outpatient ulcer clinics among participating centers. Addressing these disparities through standardized protocols, equitable resource allocation, and integration of advanced tools is essential to improve patient care and outcomes.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":"161 4","pages":"359-366"},"PeriodicalIF":2.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148818466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined use of isotretinoin and secukinumab in pediatric Darier disease: a sustained clinical response.","authors":"Caterina M Giorgio, Anna Balato, Giuseppe Argenziano, Paolino Franzese, Vincenzo Piccolo, Valentina Russo, Gaetano Licata","doi":"10.23736/S2784-8671.26.08505-1","DOIUrl":"10.23736/S2784-8671.26.08505-1","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"403-404"},"PeriodicalIF":2.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147468047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adalimumab biosimilar-induced hypertriglyceridemia in psoriasis.","authors":"Michela Tabanelli, Giulia Olivoni, Francesco Savoia","doi":"10.23736/S2784-8671.26.08530-0","DOIUrl":"10.23736/S2784-8671.26.08530-0","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"406-407"},"PeriodicalIF":2.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147771554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intradermal tranexamic acid and melasma: a systematic review and level of evidence.","authors":"Marco Piras, Gianmarco D Bigotto, Hassan Galadari, Ilaria Proietti, Eugenia V DI Brizzi, Alessia Paganelli, Steven P Nisticò, Santo R Mercuri, Nicola Zerbinati, Massimo Mammucari, Giovanni Paolino, Giovanni Pellacani, Caterina Longo, Giuseppe Argenziano, Franco Rongioletti, Stefania Guida","doi":"10.23736/S2784-8671.26.08528-2","DOIUrl":"10.23736/S2784-8671.26.08528-2","url":null,"abstract":"<p><strong>Background: </strong>Melasma is a common acquired pigmentary disorder characterized by symmetrical hyperpigmentation, mainly affecting sun-exposed areas of the face and neck. While not medically severe, melasma significantly impacts the quality of life due to cosmetic and psychological concerns. This systematic review evaluates the efficacy and safety of intradermal tranexamic acid (ID TXA) at varying dosages for melasma treatment, comparing it with established therapies such as hydroquinone (HQ), laser treatments, and oral TXA.</p><p><strong>Methods: </strong>A search of the literature was performed using the electronic databases PubMed and Ovid by selecting the words \"Melasma and mesotherapy, \"Melasma and intradermal\" and \"Melasma and injection.\"</p><p><strong>Results: </strong>The study examined ID TXA concentrations of 4 mg/mL, 100 mg/mL, and other variations. TXA 4 mg/mL showed significant improvement in melasma severity, often comparable to or better than alternative treatments like HQ 4% or laser therapy, albeit with mild and transient side effects. TXA 100 mg/mL demonstrated similar or superior efficacy to HQ and oral TXA, with a lower recurrence rate than laser therapy.</p><p><strong>Conclusions: </strong>Overall, ID TXA is a well-tolerated and effective treatment for melasma, with varying concentrations offering different efficacy and safety profiles.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"342-349"},"PeriodicalIF":2.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147981748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of paramedian forehead flap perfusion using indocyanine green and near-infrared fluorescence-guided imaging.","authors":"Carlo Bornacina, Vincenzo Barbaccia, Nicole Morini, Simone Ribero, Angelo Marzano","doi":"10.23736/S2784-8671.25.08511-1","DOIUrl":"10.23736/S2784-8671.25.08511-1","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"405-406"},"PeriodicalIF":2.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145952005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermatological manifestations in MORC2-related neuropathy and cerebellar atrophy.","authors":"Antonio DI Guardo, Alessandra Rallo, Federica Trovato, Dario Didona, Steven P Nisticò, Giovanni Pellacani","doi":"10.23736/S2784-8671.26.08561-0","DOIUrl":"10.23736/S2784-8671.26.08561-0","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"412-413"},"PeriodicalIF":2.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147305930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dupilumab as an effective therapeutic option in a severe flare of Hailey-Hailey disease triggered by scabies infestation.","authors":"Michele Lanzetti, Alessandro Magnatta, Luca Sanna, Chiara Frattini, Simone Landini, Valentina Ruffo DI Calabria, Elena B Mariotti, Alice Verdelli, Marzia Caproni","doi":"10.23736/S2784-8671.25.08494-4","DOIUrl":"10.23736/S2784-8671.25.08494-4","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"400-402"},"PeriodicalIF":2.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146105470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fordyce disease in a woman and her daughter.","authors":"Marco Piras, Antonio P Brunetti, Stefania Guida, Franco Rongioletti","doi":"10.23736/S2784-8671.26.08483-5","DOIUrl":"10.23736/S2784-8671.26.08483-5","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"398-400"},"PeriodicalIF":2.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147468041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of dermatologist in diagnosis of acquired A hemophilia.","authors":"Nunzia DI Cristo, Claudia Leporati, Lorenza Burzi, Patrizia Sciancalepore, Jacopo Agnelli Giacchello, Luigi M Castello","doi":"10.23736/S2784-8671.26.08581-6","DOIUrl":"10.23736/S2784-8671.26.08581-6","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"416-417"},"PeriodicalIF":2.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147771612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}