Italian Journal of Dermatology and Venereology最新文献_第3页

Treating psoriatic arthritis in the early phase: proposal for a shared dermatological and rheumatological therapeutic intervention with biologics and targets synthetic disease-modifying immunosuppressive drugs.

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-13 DOI: 10.23736/S2784-8671.24.07927-1

Andrea Picchianti Diamanti, Marco Galluzzo, Annunziata Dattola, Arianna D'Antonio, Augusta Ortolan, Domenico Giordano, Magda D'Agostino, Rossana Scrivo

引用次数: 0

Trichoscopic clues of the scalp in moderate to severe atopic dermatitis: a monocentric analysis.

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-10 DOI: 10.23736/S2784-8671.25.08127-7

Michela Starace, Carlotta Gurioli, Gionathan Orioni, Stephano Cedirian, Tullio Brunetti, Luca Rapparini, Bianca M Piraccini

{"title":"Trichoscopic clues of the scalp in moderate to severe atopic dermatitis: a monocentric analysis.","authors":"Michela Starace, Carlotta Gurioli, Gionathan Orioni, Stephano Cedirian, Tullio Brunetti, Luca Rapparini, Bianca M Piraccini","doi":"10.23736/S2784-8671.25.08127-7","DOIUrl":"https://doi.org/10.23736/S2784-8671.25.08127-7","url":null,"abstract":"Background: Atopic dermatitis (AD) stands as the prevailing chronic relapsing inflammatory dermatosis within the general population. Scalp involvement is a minor but frequent feature of AD, nevertheless it was relatively understudied up to now. This research aims to better describe the clinical and trichoscopic aspects of scalp involvement in moderate-to-severe AD, focusing on the vascular pattern of the vessels and scalp desquamation.Methods: A single-center retrospective and prospective study was conducted on 20 patients, collecting clinical and trichoscopic images at the Dermatology Unit of the University of Bologna, Italy.Results: Scalp lesions exhibited distinct morphological characteristics in both vascular and desquamation patterns. Three main trichoscopic patterns with a different grade of involvement were identified: erythematous pattern, erythematous desquamative pattern and exudative with crusts pattern. As for the limitations, the sample size was relatively small, and, being a single-centre study, the results may not be applicable to other populations or settings. In addition, no standardized criteria for trichoscopic analysis are available.Conclusions: This is the first study with the purpose to delineate the trichoscopic characteristics observed in patients with moderate-to-severe AD not in systemic therapy, thereby highlighting three distinct patterns of trichoscopy manifestations that define three distinct populations.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Segmental acantholytic dermatosis (Grover's disease) along Blaschko lines.

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-10 DOI: 10.23736/S2784-8671.25.07939-3

Edoardo Arlotti, Lucrezia Pacetti, Silvia Zago, Valeria Evangelista, Michela Tabanelli, Alessandro Borghi

引用次数: 0

A case of trigeminal trophic syndrome.

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-03 DOI: 10.23736/S2784-8671.24.08123-4

Federica Filippi, Francesco P Salamone, Alice N Rossi, Lidia Sacchelli, Bianca M Piraccini, Federico Bardazzi

引用次数: 0

Angiolymphoid hyperplasia with eosinophilia of the ear. 耳朵血管淋巴细胞增生伴嗜酸性粒细胞增多。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2024-11-04 DOI: 10.23736/S2784-8671.24.07966-0

Federica Li Pomi, Federico Vaccaro, Antonio Ieni, Francesco Borgia, Mario Vaccaro

引用次数: 0

Juvenile gangrenous vasculitis of the scrotum: a rare entity and a diagnostic challenge. 阴囊的少年坏疽性血管炎：一个罕见的实体和诊断的挑战。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2024-12-17 DOI: 10.23736/S2784-8671.24.08029-0

Barbara Cocuroccia, Giorgio Annessi, Enzo Palese, Siavash Rahimi, Filomena Russo

引用次数: 0

Trends in Breslow thickness of nodular and superficial spreading melanoma subtypes and associated factors: a twelve-year analysis from a tertiary referral center in Greece. 结节性和浅表扩散黑色素瘤亚型的brreslow厚度趋势及相关因素：来自希腊三级转诊中心的12年分析。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2025-01-22 DOI: 10.23736/S2784-8671.24.08129-5

Aikaterini Niforou, Pagona D Lagiou, Alan C Geller, Nick Dessypris, Alexander J Stratigos

{"title":"Trends in Breslow thickness of nodular and superficial spreading melanoma subtypes and associated factors: a twelve-year analysis from a tertiary referral center in Greece.","authors":"Aikaterini Niforou, Pagona D Lagiou, Alan C Geller, Nick Dessypris, Alexander J Stratigos","doi":"10.23736/S2784-8671.24.08129-5","DOIUrl":"10.23736/S2784-8671.24.08129-5","url":null,"abstract":"Background: Primary tumor thickness is important for prognosis of melanoma patients. To enhance prevention and quantify the true burden of melanoma, better understanding of thickness patterns and associated characteristics is crucial. Previous studies have been limited to report trends and address risk factors of thickness in specific melanoma subtypes in the Greek population. We investigated associations between epidemiological characteristics and thickness for the two most common melanoma subtypes and the trends in thickness over a twelve-year period.Methods: A retrospective study of 1201 patients with histologically confirmed primary nodular and superficial spreading melanoma (SSM) diagnosed from 2010 to 2021 in \"Andreas Sygros\" Hospital of Cutaneous and Venereal diseases was conducted. Multiple regression was performed to examine the association of variables of interest with melanoma thickness.Results: SSM thickness significantly increased by 2% per year (percent of change: 2.0, 95% CI: 0.2, 3.7) from 2010 to 2021, while a similar tendency for nodular melanoma (NM) thickness was indicated. Age at diagnosis was demonstrated to be a predictor of thickness for both subtypes. When considering all confounders, overall sun exposure was inversely associated with SSM thickness (PC: -6.2, 95% CI: -12.4, 0.5) and a similar association was indicated for NM (PC: -9.3, 95%CI: -21.1, 4.2).Conclusions: These results indicate an upward trend of SSM thickness and the associations of age at diagnosis and overall exposure to UV with thickness of both subtypes. Future research is needed to identify additional characteristics and explain differences among all melanoma types.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"20-28"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The emerging role of photodynamic therapy in the treatment of cutaneous infections. 光动力疗法在皮肤感染治疗中的新作用。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2024-11-29 DOI: 10.23736/S2784-8671.24.07910-6

Olive Anagu, Jesse Salas, Sarah Choe, Abhinav Birda, Ajay Sharma, Gabrielle Baker, Natasha Mesinkovska

{"title":"The emerging role of photodynamic therapy in the treatment of cutaneous infections.","authors":"Olive Anagu, Jesse Salas, Sarah Choe, Abhinav Birda, Ajay Sharma, Gabrielle Baker, Natasha Mesinkovska","doi":"10.23736/S2784-8671.24.07910-6","DOIUrl":"10.23736/S2784-8671.24.07910-6","url":null,"abstract":"Introduction: Cutaneous infections pose ongoing challenges to standard treatments due to resistance and limited efficacy. Photodynamic therapy (PDT) emerges as a promising supplement or an alternative to address complicated cases. In this review, we comprehensively review PDT's safety and efficacy in treating cutaneous infections.Evidence acquisition: A PubMed systematic review with search terms for PDT treatment, hair, skin, and nail infections.Evidence synthesis: There were a total of 43 studies on the use of PDT in cutaneous infections which discussed the treatment of viral (N.=20), bacterial (N.=11), fungal (N.=9), and protozoal (N.=3) infections. There is evidence for using PDT, mostly 5-aminolevulinic acid (5-ALA) and methyl aminolevulinate (MAL), in the treatment of cutaneous infections. Most evidence for viral infections involved treatment with 5-ALA PDT in condyloma acuminatum (CoAc), verruca vulgaris, and molluscum contagiosum. In bacterial infections, 5-ALA and MB PDT have been used to achieve complete remission in refractory Pseudomonas and atypical mycobacteria infections without recurrence. In onychomycosis, MAL PDT achieved a 40.9% cure rate and MB PDT showed a 77.8-100% cure rate with no reports of recurrence. Parasitic infections, such as leishmaniasis have also been successfully treated with both 5-ALA and MAL PDT.Conclusions: PDT is a promising treatment option for cutaneous infections, with growing evidence for its utility in treating cutaneous bacterial, viral, fungal, and parasitic infections, particularly those that fail standard treatments. Side effects were mostly limited to localized pain with good outcomes and low recurrence rates.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"40-46"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of intravenous immunoglobulin in autoimmune diseases with dermatological implications. 静脉注射免疫球蛋白在对皮肤有影响的自身免疫性疾病中的作用。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2024-10-03 DOI: 10.23736/S2784-8671.24.07955-6

Antonio Podo Brunetti, Carolina DE Rosa, Vanessa Bottino, Franco Rongioletti

{"title":"The role of intravenous immunoglobulin in autoimmune diseases with dermatological implications.","authors":"Antonio Podo Brunetti, Carolina DE Rosa, Vanessa Bottino, Franco Rongioletti","doi":"10.23736/S2784-8671.24.07955-6","DOIUrl":"10.23736/S2784-8671.24.07955-6","url":null,"abstract":"Intravenous immunoglobulin (IVIG) therapy has emerged as a promising treatment option for various dermatological autoimmune diseases due to its immunomodulatory potential and low incidence of severe side effects. Despite its widespread use, the mechanism of action of IVIG in treating autoimmune diseases remains a topic of debate. IVIG is derived from the plasma fractionation of a large pool of donors, primarily consisting of the IgG isotype. Its main mechanisms of action involve neutralizing circulating autoantibodies via the F(ab')2 portion, inhibiting complement-mediated tissue destruction, and reducing the half-life of circulating autoantibodies through the Fc portion. This paper explores the growing utilization of IVIG as an off-label therapy in dermatological autoimmune or immune-mediated diseases, including autoimmune bullous disease (AIBS), dermatomyositis (DM), lupus erythematosus (LE), systemic sclerosis, scleromyxedema, Stevens-Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN), pyoderma gangrenosum (PG), and necrobiotic xanthogranuloma (NXG). In this context, the sole large prospective, randomized trial was the 2022 ProDERM study, which demonstrate efficacy of IVIG in improving cutaneous manifestations among 95 DM patients compared to the placebo group. Moreover, although considered off-label, the use of IVIG is regarded as the first-line therapy for patients with scleromyxedema. As a first line of therapy, IVIg is only approved for Kawasaki Disease (KD) in the setting of vasculitis. The treatment in all other indications is mostly considered as adjuvant therapy only after failure of immunosuppressive therapy or in the presence of contraindications.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"47-54"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Keloid management: a review of treatment modalities. 瘢痕疙瘩治疗：治疗方法综述。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2024-11-19 DOI: 10.23736/S2784-8671.24.07848-4

Peter M Luo, Donald A Glass Ii

引用次数: 0