Italian Journal of Dermatology and Venereology最新文献

Efficacy of JAK inhibitors in treating dominant dystrophic epidermolysis bullosa and alopecia areata. JAK抑制剂治疗显性营养不良大疱性表皮松解和斑秃的疗效观察。

IF 2.6 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-10-03 DOI: 10.23736/S2784-8671.25.08236-2

Francesco Moro, Maria B Pupa, Jo L Sinagra, Valeria Pacifico, Federica Trovato, Anna R Giampetruzzi, Daniele Castiglia, Giovanna Floriddia, Giulia Pascolini, Mauro Picardo, Giovanni DI Zenzo, Laura Colonna

引用次数: 0

Lichen planopilaris: avoid the misdiagnosis in atypical areas. 扁平苔藓：不典型地区避免误诊。

IF 2.6 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-10-03 DOI: 10.23736/S2784-8671.25.08115-0

André L Donda, Carla J Machado, David Saceda-Corralo, Sergio Vañó-Galván, Juan Jimenez-Cauhe, Matilde Iorizzo, Federico Quadrelli, Bianca M Piraccini, Michela V Starace, Daniel F Melo

引用次数: 0

Steroid-free methotrexate and azathioprine combination in active morphea: a retrospective evaluation of efficacy and safety in nineteen adult patients. 无类固醇甲氨蝶呤联合硫唑嘌呤治疗活性吗啡：19例成人患者的疗效和安全性回顾性评价。

IF 2.6 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-10-03 DOI: 10.23736/S2784-8671.25.08364-1

Gaetano Licata, Eugenia V DI Brizzi, Graziella Babino, Elisabetta Fulgione, Giuseppe Argenziano, Caterina M Giorgio

引用次数: 0

Exploring liquid biopsy for putative biomarker in actinic keratosis and cutaneous squamous cell carcinoma. 探索液体活检在光化性角化病和皮肤鳞状细胞癌中可能的生物标志物。

IF 2.6 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-10-01 DOI: 10.23736/S2784-8671.25.08328-8

Ilaria Proietti, Emanuele Amore, Elio Pellegrini, Elisabetta DE Marinis, Stefania Guida, Concetta Potenza, Hugues Cartier, Giovanni Pellacani, Lorenzo Grimaldi, Marco Iuliano, Giorgio Mangino

引用次数: 0

Upadacitinib is efficacious in reducing the alexithymic trait in adult patients with moderate-to-severe atopic dermatitis: a prospective multicenter real-life study. Upadacitinib可有效降低中度至重度特应性皮炎成人患者的述情特征：一项前瞻性多中心现实研究。

IF 2.6 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-10-01 DOI: 10.23736/S2784-8671.25.08228-3

Eustachio Nettis, Mattia Cristallo, Carmen S Fiorella, Angela Giuliani, Vincenzo Patella, Luciana Pierro, Tiziana Peduto, Giuseppe F Amoruso, Genoveffa Scotto DI Luzio, Pietro Morrone, Martino Carriero, Pierfrancesco DE Giacomo, Massimo Triggiani, Isabella Carrieri, Ippolita Zaza, Francesco Pugliese, Marina Castriota, Stefano Pellè

{"title":"Upadacitinib is efficacious in reducing the alexithymic trait in adult patients with moderate-to-severe atopic dermatitis: a prospective multicenter real-life study.","authors":"Eustachio Nettis, Mattia Cristallo, Carmen S Fiorella, Angela Giuliani, Vincenzo Patella, Luciana Pierro, Tiziana Peduto, Giuseppe F Amoruso, Genoveffa Scotto DI Luzio, Pietro Morrone, Martino Carriero, Pierfrancesco DE Giacomo, Massimo Triggiani, Isabella Carrieri, Ippolita Zaza, Francesco Pugliese, Marina Castriota, Stefano Pellè","doi":"10.23736/S2784-8671.25.08228-3","DOIUrl":"https://doi.org/10.23736/S2784-8671.25.08228-3","url":null,"abstract":"Background: Upadacitinib has proven to be well tolerated and provided superior efficacy compared to dupilumab after 16 weeks of treatment in adult patients with moderate-to-severe atopic dermatitis (AD) in randomized clinical trials.Methods: This multicentric, prospective, observational, real-life study included 120 adult patients with moderate-to-severe AD treated with Upadacitinib at 10 Italian hospitals. We examined both physician-reported outcome measures (EASI), patient-reported outcome measures (itch, sleep and pain score [NRS], Dermatology Life Quality Index [DLQI], alexithymia [TAS-20 score]), and serological markers after 16 weeks.Results: A statistically significant reduction was recorded in all the scores analyzed, including the TAS-20 score (P<0.0001). The median (IQR) change from baseline to 16 weeks of treatment in the EASI score was 90.1 (11.3) (P<0.0001). The EASI50, EASI75 and EASI90 response rates were 95.8%, 82.5%, 50.8% (P<0.0001).Conclusions: This is the broadest multicenter real-life study in AD patients treated with upadacitinib, analyzing the reduction of the TAS-20 score. Noteworthy is the rapidity of drug effectiveness in reducing the extension of lesions and itching after just four weeks.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":"160 5","pages":"398-405"},"PeriodicalIF":2.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trichloroacetic acid in vitiligo management: mechanisms, clinical applications, and future directions. 三氯乙酸在白癜风治疗中的作用：机制、临床应用及未来发展方向。

IF 2.6 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-10-01 DOI: 10.23736/S2784-8671.25.08009-0

Ramadan S Hussein, Refaat R Hammad, Shaimaa E Badawy, Salman B Dayel, Othman Abahussein, Huda H Gafar, Abeer A El-Sherbiny, Mofreh Mansour

{"title":"Trichloroacetic acid in vitiligo management: mechanisms, clinical applications, and future directions.","authors":"Ramadan S Hussein, Refaat R Hammad, Shaimaa E Badawy, Salman B Dayel, Othman Abahussein, Huda H Gafar, Abeer A El-Sherbiny, Mofreh Mansour","doi":"10.23736/S2784-8671.25.08009-0","DOIUrl":"https://doi.org/10.23736/S2784-8671.25.08009-0","url":null,"abstract":"Vitiligo presents a therapeutic challenge due to its unpredictable course and limited treatment options for achieving repigmentation. Trichloroacetic acid (TCA), known for its keratolytic and caustic properties, has emerged as a potential adjunctive therapy in vitiligo management. This review explores the role of TCA alongside established treatment modalities, including phototherapy, topical corticosteroids, and surgical interventions. Mechanisms of action, clinical applications, safety considerations, and future research directions are discussed. TCA acts by inducing controlled chemical injury to the epidermis, facilitating exfoliation and stimulating re-epithelialization. It may also enhance melanocyte migration, proliferation, and pigment production. Combining TCA with phototherapy has shown promise in improving repigmentation rates, while adjunctive use with topical corticosteroids may augment treatment efficacy. In surgical interventions, TCA aids in preparing recipient sites and optimizing graft survival. Adverse effects of TCA include hyperpigmentation and scarring, necessitating careful patient selection and monitoring. Future research should focus on optimizing TCA protocols, conducting large-scale clinical trials, and exploring novel therapeutic combinations. Overall, TCA holds potential as a valuable adjunctive therapy in the multifaceted approach to vitiligo treatment, offering hope for improved outcomes in affected individuals.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":"160 5","pages":"423-428"},"PeriodicalIF":2.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Giardia lamblia and eczema: can they be related? 贾第鞭毛虫和湿疹：它们有关系吗？

IF 2.6 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-10-01 Epub Date: 2025-06-05 DOI: 10.23736/S2784-8671.25.08245-3

Antonio DI Guardo, Francesca P Sasso, Luca Guarino, Steven P Nisticò, Giovanni Pellacani

引用次数: 0

Bullous pemphigoid associated with canagliflozin intake. 与卡格列净摄入有关的大疱性类天疱疮。

IF 2.6 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-10-01 DOI: 10.23736/S2784-8671.25.08354-9

Dario Didona, Anna Pira, Feliciana Mariotti, Anna R Giampetruzzi, Alessandra Rallo, Vito Gomes, Biagio Didona, Giovanni DI Zenzo

引用次数: 0

Treatment of postscabies itching with calamine: results of a retrospective, multicenter, sponsor-free study. 炉甘石治疗疥疮后瘙痒：一项回顾性、多中心、无申办者研究的结果。

IF 2.6 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-10-01 DOI: 10.23736/S2784-8671.25.08267-2

Stefano Veraldi, Gianluca Nazzaro, Rossana Schianchi, Marius-Anton Ionescu

引用次数: 0

Ethical and professional use of social media: Consensus of Italian Dermatologists active on social media. 社交媒体的道德和专业使用：活跃在社交媒体上的意大利皮肤科医生的共识。

IF 2.6 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-10-01 Epub Date: 2025-07-25 DOI: 10.23736/S2784-8671.25.08264-7

Lidia Sacchelli, Marta Fusano, Laura Colli, Valentina Trevisan, Rossana Capezzera, Federica Cavallini, Lisa Cecchini, Rosa Frisario, Luciano Galotta, Maria T Luverà, Giovanni Menchini, Luigia Panariello, Michela Starace, Federica Trovato, Andrea Vizzaccaro, Federica Osti

{"title":"Ethical and professional use of social media: Consensus of Italian Dermatologists active on social media.","authors":"Lidia Sacchelli, Marta Fusano, Laura Colli, Valentina Trevisan, Rossana Capezzera, Federica Cavallini, Lisa Cecchini, Rosa Frisario, Luciano Galotta, Maria T Luverà, Giovanni Menchini, Luigia Panariello, Michela Starace, Federica Trovato, Andrea Vizzaccaro, Federica Osti","doi":"10.23736/S2784-8671.25.08264-7","DOIUrl":"10.23736/S2784-8671.25.08264-7","url":null,"abstract":"Background: Social media has transformed medical communication, providing dermatologists with opportunities for public education, professional visibility, and patient engagement. However, ethical and professional concerns arise due to the lack of dermatology-specific guidelines in Italy. While the National Federation of Orders of Physicians and Dentists (FNOMCeO) offers general recommendations, no targeted framework exists to regulate dermatologists' digital presence.Methods: During the 32nd Annual AIDA Congress in May 2024, a working group of 23 dermatologists with active online engagement was formed. Existing ethical frameworks, including the Code of Medical Ethics, were reviewed to identify regulatory gaps. A core team drafted 12 statements, which were refined through a structured discussion and a vote to reach consensus.Results: The working group developed 12 best practice statements covering key aspects of ethical online engagement, including responsible social media use, conflict-of-interest disclosures, adherence to scientific evidence, patient privacy, and the fight against misinformation. These statements establish clear principles to guide dermatologists in their digital communication.Conclusions: This is the first dermatology-specific digital communication consensus in Italy, addressing an urgent need for ethical regulation. These recommendations provide a structured framework for dermatologists, ensuring responsible online engagement while maximizing public health impact. Further regulatory efforts are essential to maintain high professional and ethical standards in the digital era.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"413-417"},"PeriodicalIF":2.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0