Filomena Russo, Donatella Sordi, Anna R Giampetruzzi, Anna Dattolo, Sabatino Pallotta, Enrico Scala, Siavash Rahimi, Ornella DE Pità, Barbara Cocuroccia
{"title":"Erythrodermic atopic dermatitis successfully treated with upadacitinib.","authors":"Filomena Russo, Donatella Sordi, Anna R Giampetruzzi, Anna Dattolo, Sabatino Pallotta, Enrico Scala, Siavash Rahimi, Ornella DE Pità, Barbara Cocuroccia","doi":"10.23736/S2784-8671.25.08107-1","DOIUrl":"https://doi.org/10.23736/S2784-8671.25.08107-1","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michele Lanzetti, Filippo Toaiari, Emanuele M Cipollini, Daniela Massi, Ilaria C Galli, Emiliano Antiga
{"title":"Unveiling the bridge between neutrophilic and autoinflammatory spectrum. Good response to old but gold colchicine in a complex clinical association of Sweet Syndrome with psoriasis and hidradenitis suppurativa under treatment with ixekizumab.","authors":"Michele Lanzetti, Filippo Toaiari, Emanuele M Cipollini, Daniela Massi, Ilaria C Galli, Emiliano Antiga","doi":"10.23736/S2784-8671.25.08202-7","DOIUrl":"https://doi.org/10.23736/S2784-8671.25.08202-7","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144475160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michela Starace, Bor Hrvatin Stancic, Stephano Cedirian, Federico Quadrelli, Francesca Pampaloni, Francesca Bruni, Aurora Alessandrini, Cosimo Misciali, Bianca M Piraccini
{"title":"Alopecia areata incognita in men masquerading as androgenetic alopecia: a case series of 29 patients in a single centre experience.","authors":"Michela Starace, Bor Hrvatin Stancic, Stephano Cedirian, Federico Quadrelli, Francesca Pampaloni, Francesca Bruni, Aurora Alessandrini, Cosimo Misciali, Bianca M Piraccini","doi":"10.23736/S2784-8671.25.08170-8","DOIUrl":"https://doi.org/10.23736/S2784-8671.25.08170-8","url":null,"abstract":"<p><strong>Background: </strong>Alopecia areata incognita (AAI) represents a variant of alopecia areata with an absence of well-defined alopecic patches but diffuse involvement of the scalp and even if usually affected females, it may also appear in male. Little is known about AAI in men. The aim of this study was to characterize the history, clinical, trichoscopic, and histopathologic features of AAI in male patients.</p><p><strong>Methods: </strong>All histopathologically proven male patients with AAI between April 2011 and December 2023, were included in the study. The history, clinical, trichoscopic and histopathologic features of the male patients were evaluated.</p><p><strong>Results: </strong>Twenty-nine patients with AAI were included in the study, the mean age was 23.1. All patients had an underlying androgenetic alopecia (AGA) - Hamilton Scale: 17 (58.62%) grade IV, 9 (31.03%) grade V and 3 (10.34%) grade VI. The most common trichoscopic features included short regrowing hair (96.6%), yellow dots (89.7%) and pigtail hair (41.3%) especially seen in the occipital, parietal and frontal regions. A positive pull test with telogen roots was observed in 24.1% of the patients. Histopathological characteristics of AAI in male patients were indistinguishable from previously described features in female patients. All patients were treated with an ultra-potent topical corticosteroid under occlusion and topical 5% minoxidil twice/day or oral minoxidil, remission was established between 4-8 months after treatment initiation.</p><p><strong>Conclusions: </strong>A thorough trichoscopic examination in cases of diffuse hair loss in male patients with AGA refractory to conventional therapy is warranted and trichoscopy-guided biopsy is necessary to confirm the diagnosis.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144475159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antonio DI Guardo, Francesca P Sasso, Luca Guarino, Steven P Nisticò, Giovanni Pellacani
{"title":"Giardia lamblia and eczema: can they be related?","authors":"Antonio DI Guardo, Francesca P Sasso, Luca Guarino, Steven P Nisticò, Giovanni Pellacani","doi":"10.23736/S2784-8671.25.08245-3","DOIUrl":"https://doi.org/10.23736/S2784-8671.25.08245-3","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martina Maurelli, Paolo Gisondi, Giampiero Girolomoni
{"title":"Gender perspective in the management of psoriasis.","authors":"Martina Maurelli, Paolo Gisondi, Giampiero Girolomoni","doi":"10.23736/S2784-8671.25.08147-2","DOIUrl":"https://doi.org/10.23736/S2784-8671.25.08147-2","url":null,"abstract":"<p><p>Gender medicine has been achieving increasing importance. Gender differences in disease depend on hormonal status and may involve functions of the skin, immune responses and metabolic pathways, and have to do also with indications and response to treatments. Psoriasis is a common chronic inflammatory immune-mediated disease. The prevalence of psoriasis in the population is balanced between males and females, but early onset psoriasis is slightly more prevalent in males, with the latter suffering from a more severe disease. In general, male and female patients receive identical drugs at equivalent dosages. However, females receive systemic treatments less frequently compared to males. Males are more satisfied with their psoriasis treatment and respond better to biologics. Females have a significant higher rate of adverse events and drug-related discontinuation rate compared to males. About conventional systemic treatments for psoriasis during pregnancy, only cyclosporine is suggested when the benefits exceed the potential side effects, whereas methotrexate is contraindicated during pregnancy and lactation and in the three months before fatherhood and motherhood. Among the biologics, only certolizumab pegol is considered safe in pregnant patients, as it does not cross the maternal-placental barrier. Therefore, it is important to consider a gender perspective in the treatment of psoriasis, including her willingness to procreate. This is a narrative review highlighting the challenges that the healthcare dermatologists may face regarding management of psoriasis in female patients.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multiple sentinel lymph node biopsies in a patient with multiple melanomas: report of a one-time surgical session.","authors":"Gabriele Roccuzzo, Silvia Borriello, Simone Ribero, Pietro Quaglino, Adriana Lesca, Franco Picciotto","doi":"10.23736/S2784-8671.25.08230-1","DOIUrl":"https://doi.org/10.23736/S2784-8671.25.08230-1","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Albendazole in the era of scabies resistance is better.","authors":"Alessio Natale, Stephano Cedirian, Michela Starace, Iria Neri, Valeria Evangelista, Corrado Zengarini, Bianca M Piraccini","doi":"10.23736/S2784-8671.25.08168-X","DOIUrl":"https://doi.org/10.23736/S2784-8671.25.08168-X","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of human eye in resource-limited settings: preserving essential diagnostic skills in dermatology.","authors":"Rebecca Donadoni, Valeria Brazzelli","doi":"10.23736/S2784-8671.25.08242-8","DOIUrl":"https://doi.org/10.23736/S2784-8671.25.08242-8","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Valerio Cirfera, Maurizio Congedo, Camila Scharf, Marco Polo, Cosimo Prete, Andrea Rosafio, Enrico M Procaccini
{"title":"Telemedicine and teledermatology between technological innovation and professional responsibility in Italy.","authors":"Valerio Cirfera, Maurizio Congedo, Camila Scharf, Marco Polo, Cosimo Prete, Andrea Rosafio, Enrico M Procaccini","doi":"10.23736/S2784-8671.25.08046-6","DOIUrl":"10.23736/S2784-8671.25.08046-6","url":null,"abstract":"<p><p>Telemedicine utilizes communication technologies to provide healthcare services remotely, significantly impacting dermatology through the transmission and analysis of body surface images. Despite its benefits, telemedicine faces challenges including the quality of tools, operator competence, privacy issues, and responsibility allocation in cases of errors. The Italian Code of Medical Deontology emphasizes safety, proportionality, and the necessity of in-person examinations for initial consultations. Teleconsultations, online visits, and telemonitoring are essential forms of telemedicine that must adhere to ethical guidelines and protect patient privacy. Legal frameworks such as the Gelli-Bianco Law mandate professional responsibility and insurance coverage for telemedicine practices, equating them with traditional medical services. Legal challenges include data protection, informed consent, and the distribution of responsibility among healthcare providers and technology operators. Telemedicine, including teledermatology, offers substantial benefits but should not replace traditional in-person consultations, particularly in complex cases like dermato-oncology. Successful implementation requires a balanced approach, prioritizing patient well-being and professional responsibility. In conclusion, telemedicine provides an opportunity to enhance healthcare delivery, extending beyond physical and geographical limitations. However, it must complement traditional practices to optimize healthcare outcomes, adhering to all ethical and legal standards. Telemedicine's success hinges on a common-sense approach that emphasizes patient well-being, professional responsibility, and the integration of technological innovations into routine healthcare.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":"160 3","pages":"219-224"},"PeriodicalIF":1.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oliver Brandt, Jie Zhu, Manfred Hartard, Simon M Mueller
{"title":"Bad vibrations? The prevalence of itch and erythema induced by whole body vibration training: a questionnaire-based study in users and therapists.","authors":"Oliver Brandt, Jie Zhu, Manfred Hartard, Simon M Mueller","doi":"10.23736/S2784-8671.25.07942-3","DOIUrl":"10.23736/S2784-8671.25.07942-3","url":null,"abstract":"<p><strong>Background: </strong>The phenomenon of itch and erythema induced by whole body vibration (WBV) is extensively discussed in social media and popular press. The existence of this phenomenon has been confirmed in an experimental study by our group, however, its prevalence and dependency on technical settings (e.g. device, frequency, amplitude, intervals) has not been studied so far.</p><p><strong>Methods: </strong>This cross-sectional, questionnaire-based, multi-center study aimed to investigate itch and erythema in the use of WBV devices. Specially designed questionnaires were used to collect data on itch and/or erythema occurrence during WBV training, allergies, antiallergic drug intake, and technical aspects and settings of WBV.</p><p><strong>Results: </strong>A total of 67 WBV users and 15 therapists administering WBV participated. Of the 67 WBV-users, 22% experienced either itch or erythema. A majority of those with itch also had erythema, which often appeared during the first session and persisted in subsequent sessions. No permanent discontinuation of WBV-treatment due to symptoms was reported. While symptoms were more prevalent for side-to-side alternating vibration devices with a pooled prevalence of 31.4%, no symptoms were reported for the tri-planar device (P<0.001).</p><p><strong>Conclusions: </strong>In conclusion, itch and erythema may be underreported side effects experienced by WBV users, and appear to be related to the type of WBV device used.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":"160 3","pages":"212-218"},"PeriodicalIF":1.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}