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Italian Journal of Dermatology and Venereology最新文献

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A case of trigeminal trophic syndrome.
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2025-02-03 DOI: 10.23736/S2784-8671.24.08123-4
Federica Filippi, Francesco P Salamone, Alice N Rossi, Lidia Sacchelli, Bianca M Piraccini, Federico Bardazzi
{"title":"A case of trigeminal trophic syndrome.","authors":"Federica Filippi, Francesco P Salamone, Alice N Rossi, Lidia Sacchelli, Bianca M Piraccini, Federico Bardazzi","doi":"10.23736/S2784-8671.24.08123-4","DOIUrl":"https://doi.org/10.23736/S2784-8671.24.08123-4","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy and safety of risankizumab for the treatment of patients with plaque type psoriasis.
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2025-01-30 DOI: 10.23736/S2784-8671.24.07996-9
Fan Lin, Tsen-Fang Tsai
{"title":"Efficacy and safety of risankizumab for the treatment of patients with plaque type psoriasis.","authors":"Fan Lin, Tsen-Fang Tsai","doi":"10.23736/S2784-8671.24.07996-9","DOIUrl":"https://doi.org/10.23736/S2784-8671.24.07996-9","url":null,"abstract":"<p><p>Risankizumab (Skyrizi<sup>®</sup>, Abbvie, North Chicago, IL, USA) is a humanized immunoglobulin (Ig) G1 monoclonal antibody targeting the p19 subunit of IL-23, thereby inhibiting IL-23-dependent releasing of proinflammatory cytokines in plaque psoriasis. Risankizumab is licensed is most countries for the treatment of patients with moderate-to-severe plaque psoriasis, and in Japan for generalized pustular psoriasis, erythrodermic psoriasis and palmoplantar pustulosis. Risankizumab showed higher efficacy and favorable safety profiles in patients with moderate-to-severe plaque psoriasis, compared with adalimumab, secukinumab and ustekinumab in several randomized controlled phase 3 pivotal studies and among real-life data in large retrospective studies. Furthermore, its high efficacy even in patients with prior biologic failure, better drug survival, less need for biologic switch and longer drug-free remission durations have also been shown in real-life settings and in long-term follow up. In addition, reports of both reduced dosing and increased (bolus) dosing exist which increase our ability to use risankizumab more flexibly in an era of personalized medicine. Also, the use of risankizumab in several special population, such as elderly, Asian people, erythrodermic psoriasis, patients with high induction doses, pregnancy and human immunodeficiency virus group are discussed.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sitosterolemia: a new ABCG5 mutation.
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2025-01-30 DOI: 10.23736/S2784-8671.24.08007-1
Jacqueline Kussini, Dario Didona, Erhard Bierhoff, Ursula Steinert, Markus Steinert
{"title":"Sitosterolemia: a new ABCG5 mutation.","authors":"Jacqueline Kussini, Dario Didona, Erhard Bierhoff, Ursula Steinert, Markus Steinert","doi":"10.23736/S2784-8671.24.08007-1","DOIUrl":"https://doi.org/10.23736/S2784-8671.24.08007-1","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy and safety of treatment with biological drugs in psoriasis patients with a history of malignancies: a single-center observational study.
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2025-01-27 DOI: 10.23736/S2784-8671.25.08035-1
Edoardo Mortato, Giorgia Sbarra, Riccardo Viola, Alexandre R Meduri, Felice Primavera, Francesco Loconsole
{"title":"Efficacy and safety of treatment with biological drugs in psoriasis patients with a history of malignancies: a single-center observational study.","authors":"Edoardo Mortato, Giorgia Sbarra, Riccardo Viola, Alexandre R Meduri, Felice Primavera, Francesco Loconsole","doi":"10.23736/S2784-8671.25.08035-1","DOIUrl":"https://doi.org/10.23736/S2784-8671.25.08035-1","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in Breslow thickness of nodular and superficial spreading melanoma subtypes and associated factors: a twelve-year analysis from a tertiary referral center in Greece. 结节性和浅表扩散黑色素瘤亚型的brreslow厚度趋势及相关因素：来自希腊三级转诊中心的12年分析。
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2025-01-22 DOI: 10.23736/S2784-8671.24.08129-5
Aikaterini Niforou, Pagona D Lagiou, Alan C Geller, Nick Dessypris, Alexander J Stratigos
{"title":"Trends in Breslow thickness of nodular and superficial spreading melanoma subtypes and associated factors: a twelve-year analysis from a tertiary referral center in Greece.","authors":"Aikaterini Niforou, Pagona D Lagiou, Alan C Geller, Nick Dessypris, Alexander J Stratigos","doi":"10.23736/S2784-8671.24.08129-5","DOIUrl":"https://doi.org/10.23736/S2784-8671.24.08129-5","url":null,"abstract":"<p><strong>Background: </strong>Primary tumor thickness is important for prognosis of melanoma patients. To enhance prevention and quantify the true burden of melanoma, better understanding of thickness patterns and associated characteristics is crucial. Previous studies have been limited to report trends and address risk factors of thickness in specific melanoma subtypes in the Greek population. We investigated associations between epidemiological characteristics and thickness for the two most common melanoma subtypes and the trends in thickness over a twelve-year period.</p><p><strong>Methods: </strong>A retrospective study of 1201 patients with histologically confirmed primary nodular and superficial spreading melanoma (SSM) diagnosed from 2010 to 2021 in \"Andreas Sygros\" Hospital of Cutaneous and Venereal diseases was conducted. Multiple regression was performed to examine the association of variables of interest with melanoma thickness.</p><p><strong>Results: </strong>SSM thickness significantly increased by 2% per year (percent of change: 2.0, 95% CI: 0.2, 3.7) from 2010 to 2021, while a similar tendency for nodular melanoma (NM) thickness was indicated. Age at diagnosis was demonstrated to be a predictor of thickness for both subtypes. When considering all confounders, overall sun exposure was inversely associated with SSM thickness (PC: -6.2, 95% CI: -12.4, 0.5) and a similar association was indicated for NM (PC: -9.3, 95%CI: -21.1, 4.2).</p><p><strong>Conclusions: </strong>These results indicate an upward trend of SSM thickness and the associations of age at diagnosis and overall exposure to UV with thickness of both subtypes. Future research is needed to identify additional characteristics and explain differences among all melanoma types.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estimates of the burden of skin melanoma in Italy: update to 2024. 意大利皮肤黑色素瘤负担估计：更新至2024年。
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2025-01-22 DOI: 10.23736/S2784-8671.24.08033-2
Emanuele Crocetti, Federica Zamagni, Fabio Falcini, Rosa Vattiato, Flavia Baldacchini, Chiara Balducci, Orietta Giuliani, Silvia Mancini, Alessandra Ravaioli, Benedetta Vitali, Lauro Bucchi
{"title":"Estimates of the burden of skin melanoma in Italy: update to 2024.","authors":"Emanuele Crocetti, Federica Zamagni, Fabio Falcini, Rosa Vattiato, Flavia Baldacchini, Chiara Balducci, Orietta Giuliani, Silvia Mancini, Alessandra Ravaioli, Benedetta Vitali, Lauro Bucchi","doi":"10.23736/S2784-8671.24.08033-2","DOIUrl":"https://doi.org/10.23736/S2784-8671.24.08033-2","url":null,"abstract":"<p><strong>Background: </strong>The epidemiology of skin melanoma (SM) is rapidly changing. Therefore, we aimed at updating up to 2024 the Italian estimates on SM providing the number of incident and prevalent cases, the deaths and the distribution by stage at diagnosis.</p><p><strong>Methods: </strong>Incidence was extrapolated from age- and sex-specific International Agency for Research on Cancer (IARC) estimates from 2022 to 2025. For mortality, we applied to the most recent observed deaths, the average sex- and age-specific annual percent change estimated by the IARC from 2022 to 2025. Regarding SM prevalence, we assumed the age- and sex-specific annual change in the number of prevalent cases observed from 2010 to 2020 to be stable until 2024. Finally, we applied the average distribution by TNM-8 stages of four population-based SM series to provide a possible stage distribution at diagnosis.</p><p><strong>Results: </strong>We estimated almost 13,800 newly diagnosed SMs (54% men and 82% people older than 44 years), 2240 deaths (60% men and 49% people older than 74 years) and about 216,000 prevalent cases (51% women). At diagnosis, around 10,240 cases are expected to be stage I, 2120 stage II, 1100 stage III and 327 stage IV. As regards stage I 79% will be IA. Among stage II we expect 44% IIA, 33% IIB and 22% IIC. Among stage III, 49% case are expected to be IIIC.</p><p><strong>Conclusions: </strong>These estimates allow clinicians and policymakers to quantify and properly address the burden of SM patients' diagnostic, therapeutic and supportive needs.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sarcoidosis-like reaction induced by dupilumab. dupilumab诱导的结节病样反应。
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2025-01-22 DOI: 10.23736/S2784-8671.24.07854-X
Lucia Peterle, Laura Macca, Federico Vaccaro, Francesco Borgia, Michele Gaeta, Maria Lentini, Mario Vaccaro
{"title":"Sarcoidosis-like reaction induced by dupilumab.","authors":"Lucia Peterle, Laura Macca, Federico Vaccaro, Francesco Borgia, Michele Gaeta, Maria Lentini, Mario Vaccaro","doi":"10.23736/S2784-8671.24.07854-X","DOIUrl":"https://doi.org/10.23736/S2784-8671.24.07854-X","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Belimumab as a potential therapeutic option for bullous systemic lupus erythematosus. 贝利单抗作为大疱性系统性红斑狼疮的潜在治疗选择。
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2025-01-22 DOI: 10.23736/S2784-8671.24.08057-5
Carolina Donelli, Cristiana Barreca, Laura Calabrese, Pietro Rubegni, Laura Lazzeri
{"title":"Belimumab as a potential therapeutic option for bullous systemic lupus erythematosus.","authors":"Carolina Donelli, Cristiana Barreca, Laura Calabrese, Pietro Rubegni, Laura Lazzeri","doi":"10.23736/S2784-8671.24.08057-5","DOIUrl":"https://doi.org/10.23736/S2784-8671.24.08057-5","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Juvenile gangrenous vasculitis of the scrotum: a rare entity and a diagnostic challenge. 阴囊的少年坏疽性血管炎：一个罕见的实体和诊断的挑战。
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2024-12-17 DOI: 10.23736/S2784-8671.24.08029-0
Barbara Cocuroccia, Giorgio Annessi, Enzo Palese, Siavash Rahimi, Filomena Russo
{"title":"Juvenile gangrenous vasculitis of the scrotum: a rare entity and a diagnostic challenge.","authors":"Barbara Cocuroccia, Giorgio Annessi, Enzo Palese, Siavash Rahimi, Filomena Russo","doi":"10.23736/S2784-8671.24.08029-0","DOIUrl":"https://doi.org/10.23736/S2784-8671.24.08029-0","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142836022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unveiling new entities in the PAPA spectrum. 揭开 PAPA 频谱中新实体的面纱。
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2024-12-01 Epub Date: 2024-11-07 DOI: 10.23736/S2784-8671.24.07985-4
Alessia Paganelli, Elena Rossi, Olga Calabrese, Laura Bigi, Biagio Cuffari, Anna M Cesinaro, Alberico Motolese
{"title":"Unveiling new entities in the PAPA spectrum.","authors":"Alessia Paganelli, Elena Rossi, Olga Calabrese, Laura Bigi, Biagio Cuffari, Anna M Cesinaro, Alberico Motolese","doi":"10.23736/S2784-8671.24.07985-4","DOIUrl":"10.23736/S2784-8671.24.07985-4","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"677-678"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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