Italian Journal of Dermatology and Venereology最新文献_第10页

A case of widespread furuncular cutaneous myiasis in a man returning from Senegal. 一名从塞内加尔回国的男子患上广泛的疖状皮肤肌炎。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2024-10-01 Epub Date: 2024-07-09 DOI: 10.23736/S2784-8671.24.07901-5

Carolina DE Rosa, Antonio Podo Brunetti, Stefania Guida, Gianmarco D Bigotto, Giorgio Stabile, Franco Rongioletti

引用次数: 0

Evaluation of demographic and clinical characteristics of 728 patients with mycosis fungoides and their relationship with systemic comorbidities: multicenter, registry-based (MF-TR) study from Türkiye. 评估 728 名真菌病患者的人口统计学和临床特征及其与全身性合并症的关系：来自土耳其的多中心、基于登记的 (MF-TR) 研究。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2024-10-01 Epub Date: 2024-08-02 DOI: 10.23736/S2784-8671.24.07792-2

Didem Kazan, Dilek Bayramgürler, Hatice E Şanli, Nahide Onsun, Serkan Yazici, Esra Adişen, Bahar S Dikicier, Burhan Engin, Ayşe Öktem, Günseli Öztürk, Ayda Acar, Aslı A Çerman, Selda P Kartal, Dilek S Gençosmanoğlu, Mehmet Melikoğlu, Aslı Bilgiç

{"title":"Evaluation of demographic and clinical characteristics of 728 patients with mycosis fungoides and their relationship with systemic comorbidities: multicenter, registry-based (MF-TR) study from Türkiye.","authors":"Didem Kazan, Dilek Bayramgürler, Hatice E Şanli, Nahide Onsun, Serkan Yazici, Esra Adişen, Bahar S Dikicier, Burhan Engin, Ayşe Öktem, Günseli Öztürk, Ayda Acar, Aslı A Çerman, Selda P Kartal, Dilek S Gençosmanoğlu, Mehmet Melikoğlu, Aslı Bilgiç","doi":"10.23736/S2784-8671.24.07792-2","DOIUrl":"10.23736/S2784-8671.24.07792-2","url":null,"abstract":"Background: Mycosis fungoides (MF) is the most common cutaneous lymphoma with a chronic disease course. MF patients may also suffer from systemic comorbidities such as cardiovascular and metabolic diseases.Methods: In this study, we aimed to evaluate the demographic and clinical features of MF patients registered in the MF-TR registry system and to examine the relationship of these features with systemic comorbidities. We collected the data from the medical files of the patients via the MF-TR registry system.Results: Our study included 728 patients with MF, of which 396 (54.40%) were male and 332 (45.60%) were female. The most common additional systemic disease observed was hypertension, affecting 124 (17.03%) patients. This was followed by multinodular goiter in 66 (9.06%) patients, and diabetes mellitus type 2 in 61 (8.37%) patients. Twenty-two (3.02%) patients had a history of another secondary malignancy, with lung cancer being the most common type, affecting 5 (0.68%) patients. Female gender and high BMI were statistically higher in MF patients with asthma (P=0.019 and P=0.031, respectively). In patients with hypertension and hypercholesterolemia, the duration of diagnosis was significantly longer (P=0.013 and P=0.047, respectively).Conclusions: Dermatologists should be aware of these accompanying comorbidities in patients with MF. Multidisciplinary evaluation should be performed in the follow-up, if necessary.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"484-488"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141874812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cutaneous Rosai-Dorfman disease arising in a patient with psoriatic arthritis. 一名银屑病关节炎患者的皮肤罗赛-多夫曼病。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2024-10-01 Epub Date: 2024-07-23 DOI: 10.23736/S2784-8671.24.07899-X

Chiara Battilotti, Ina Tudurachi, Carlo Capilungo, Mauro Alaibac

引用次数: 0

A case of aquagenic wrinkling of the palms triggered by isotretinoin. 一例异维A酸引发的手掌水肿性皱纹。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2024-10-01 DOI: 10.23736/S2784-8671.24.07819-8

Vincenzo Picone, Maria C Annunziata, Luigi Coronella, Maddalena Napolitano

引用次数: 0

Understanding and managing locally advanced basal cell carcinoma: insights into pathogenesis, therapeutic strategies, and the role of hedgehog pathway inhibitors. 了解和管理局部晚期基底细胞癌：对发病机制、治疗策略和刺猬通路抑制剂作用的见解。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2024-10-01 DOI: 10.23736/S2784-8671.24.07993-3

Marta Cebolla-Verdugo, Carlos Llamas-Segura, Juan P Velasco-Amador, Francisco M Almazán-Fernández, Ricardo Ruiz-Villaverde

{"title":"Understanding and managing locally advanced basal cell carcinoma: insights into pathogenesis, therapeutic strategies, and the role of hedgehog pathway inhibitors.","authors":"Marta Cebolla-Verdugo, Carlos Llamas-Segura, Juan P Velasco-Amador, Francisco M Almazán-Fernández, Ricardo Ruiz-Villaverde","doi":"10.23736/S2784-8671.24.07993-3","DOIUrl":"https://doi.org/10.23736/S2784-8671.24.07993-3","url":null,"abstract":"Understanding and managing locally advanced basal cell carcinoma (BCC) is crucial given its substantial prevalence and potential for local tissue destruction. While BCC typically exhibits low metastatic potential, its high incidence underscores the need for enhanced therapeutic strategies. Locally advanced BCC presents unique challenges, often necessitating aggressive interventions to prevent disfigurement and functional impairment. The emergence of hedgehog pathway inhibitors (HHIs) offers promising therapeutic avenues by targeting aberrant hedgehog signaling, a key driver in BCC pathogenesis. Thus, elucidating the pathogenesis of locally advanced BCC and exploring the role of HHIs are critical endeavors in effectively managing this prevalent carcinoma. Epidemiologically, BCC primarily affects individuals with fair skin and chronic sun exposure, with an increasing incidence noted among younger age groups. Risk factors include UV radiation exposure, familial history of skin cancer, immunosuppression, and genetic syndromes such as basal cell nevus syndrome and xeroderma pigmentosum. Pathogenetically, BCC arises from cells in the skin's epidermis, with hedgehog pathway activation being a primary genetic driver, involving mutations in PTCH1 and SMO. Resistance to hedgehog inhibitors may occur due to genetic changes, complicating treatment strategies. BCC is characterized by low immunogenicity, which hinders immune response and contributes to treatment challenges. Enhanced understanding of the epidemiology, risk factors, and pathogenesis of locally advanced BCC, along with the development of targeted therapeutic approaches such as hedgehog pathway inhibitors, is essential for effectively managing this prevalent carcinoma and improving patient outcomes.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":"159 5","pages":"530-542"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Radiation-induced angiosarcoma of the breast: an uncommon polymorphic disorder. 辐射诱发的乳腺血管肉瘤：一种不常见的多形性疾病。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2024-10-01 Epub Date: 2024-06-17 DOI: 10.23736/S2784-8671.24.07827-7

Federico Gianessi, Giulia Toni, Lucrezia Pacetti, Alba Gaban, Giulia Odorici, Alessandro Borghi

引用次数: 0

Revisiting risankizumab: a newer biologic drug in dermatology. 重新审视利桑珠单抗：皮肤病学中的新型生物药物。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2024-10-01 DOI: 10.23736/S2784-8671.24.07971-4

Aditya K Bubna, Vinayak Viplav

{"title":"Revisiting risankizumab: a newer biologic drug in dermatology.","authors":"Aditya K Bubna, Vinayak Viplav","doi":"10.23736/S2784-8671.24.07971-4","DOIUrl":"https://doi.org/10.23736/S2784-8671.24.07971-4","url":null,"abstract":"Introduction: Risankizumab is an interleukin 23p19 inhibitor, approved by the USA Food and Drug Administration (FDA) for the management of moderate to severe plaque psoriasis. Apart from its utility in psoriasis, there are a number of other dermatologic conditions where risankizumab has demonstrated value. The aim of this narrative review is to describe the utility of risankizumab in psoriasis, as well as its implication in off-label dermatologic disorders.Evidence acquisition: PubMed, Google Scholar, Scopus and ResearchGate were searched for scholarly articles related to risankizumab and its utility in dermatology using the search terms \"Risankizumab\" AND \"Psoriasis\" AND \"other dermatological disorders.\"Evidence synthesis: Risankizumab is a valuable biologic agent for the management of psoriasis and psoriatic arthropathy. It has also been used successfully for other dermatologic disorders like hidradenitis suppurativa, pityriasis rubra pilaris and pyoderma gangrenosum.Conclusions: Risankizumab's usage is not limited to psoriasis. Its benefit extends to many more dermatologic conditions. Besides, it has an acceptable safety profile.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":"159 5","pages":"543-554"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acneiform rash associated with amivantamab, a novel anti-EGFR treatment for NSCLC. 与阿米万他单抗（一种治疗 NSCLC 的新型抗EGFR 药物）相关的痤疮样皮疹。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2024-10-01 Epub Date: 2024-07-04 DOI: 10.23736/S2784-8671.24.07840-X

Orsola Crespi, Valentina Celoria, Francois Rosset, Simone Ribero, Pietro Quaglino

引用次数: 0

ChatGPT and dermatology. ChatGPT 和皮肤科。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2024-10-01 Epub Date: 2024-07-23 DOI: 10.23736/S2784-8671.24.07928-3

Michela D'Agostino, Federica Feo, Fabrizio Martora, Lucia Genco, Matteo Megna, Sara Cacciapuoti, Alessia Villani, Luca Potestio

引用次数: 0

Knowledge and attitudes regarding sexually transmitted infections among healthcare workers. 医护人员对性传播感染的认识和态度。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2024-10-01 Epub Date: 2024-07-23 DOI: 10.23736/S2784-8671.24.07773-9

Giulia Ciccarese, Ilaria Salvi, Giorgio Oddenino, Giulia Silvestrini, Maria G Mavilia, Aurora Parodi, Francesco Drago

{"title":"Knowledge and attitudes regarding sexually transmitted infections among healthcare workers.","authors":"Giulia Ciccarese, Ilaria Salvi, Giorgio Oddenino, Giulia Silvestrini, Maria G Mavilia, Aurora Parodi, Francesco Drago","doi":"10.23736/S2784-8671.24.07773-9","DOIUrl":"10.23736/S2784-8671.24.07773-9","url":null,"abstract":"Background: Healthcare workers have a fundamental role in providing care and education on sexually transmitted infections (STIs). However, their knowledge is often worryingly limited. This study aimed to assess the real knowledge and attitude regarding STIs among healthcare workers of the IRCCS Ospedale Policlinico San Martino, Genoa, Italy.Methods: The recruited subjects were asked to complete a 31-item questionnaire, divided into 3 sections: socio-demographic context, knowledge about STIs, and personal sexual behavior.Results: We enrolled 140 subjects, employed as nurses (52.9%), physicians (12.9%), laboratory technicians (7.1%), or other workers (27.1%). Despite the generalized erroneous belief of having a good level of knowledge on the matter, only one-third of the subjects could correctly identify STIs among a list of diseases, and less than one-third correctly recognize all possible ways of transmission. Human immunodeficiency virus (HIV) was the most frequently recognized STI (97%), but only 39.2% of healthcare workers were correctly informed about the body fluids that can transmit the virus. Most participants (93.5%) correctly identified condoms as effective in preventing STIs but did not indicate complete abstinence as the only way to guarantee protection against STIs. Most participants were informed on the oncogenic potential of human papillomavirus (HPV) infections (82%), the usefulness of the Pap test (85.7%), and the existence of vaccines against some STIs (63.5%).Conclusions: Overall, healthcare workers have limited knowledge about STIs. Creating specific educational programs aimed at healthcare providers should become a priority.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"489-495"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141748158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0