{"title":"Trichoscopic clues of the scalp in moderate to severe atopic dermatitis: a monocentric analysis.","authors":"Michela Starace, Carlotta Gurioli, Gionathan Orioni, Stephano Cedirian, Tullio Brunetti, Luca Rapparini, Bianca M Piraccini","doi":"10.23736/S2784-8671.25.08127-7","DOIUrl":"10.23736/S2784-8671.25.08127-7","url":null,"abstract":"<p><strong>Background: </strong>Atopic dermatitis (AD) stands as the prevailing chronic relapsing inflammatory dermatosis within the general population. Scalp involvement is a minor but frequent feature of AD, nevertheless it was relatively understudied up to now. This research aims to better describe the clinical and trichoscopic aspects of scalp involvement in moderate-to-severe AD, focusing on the vascular pattern of the vessels and scalp desquamation.</p><p><strong>Methods: </strong>A single-center retrospective and prospective study was conducted on 20 patients, collecting clinical and trichoscopic images at the Dermatology Unit of the University of Bologna, Italy.</p><p><strong>Results: </strong>Scalp lesions exhibited distinct morphological characteristics in both vascular and desquamation patterns. Three main trichoscopic patterns with a different grade of involvement were identified: erythematous pattern, erythematous desquamative pattern and exudative with crusts pattern. As for the limitations, the sample size was relatively small, and, being a single-centre study, the results may not be applicable to other populations or settings. In addition, no standardized criteria for trichoscopic analysis are available.</p><p><strong>Conclusions: </strong>This is the first study with the purpose to delineate the trichoscopic characteristics observed in patients with moderate-to-severe AD not in systemic therapy, thereby highlighting three distinct patterns of trichoscopy manifestations that define three distinct populations.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"109-115"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Head and neck dermatitis: a variant of atopic dermatitis.","authors":"Leszek Blicharz, Agnieszka Michalczyk, Małgorzata Maj, Joanna Czuwara, Małgorzata Olszewska, Lidia Rudnicka","doi":"10.23736/S2784-8671.25.08001-6","DOIUrl":"https://doi.org/10.23736/S2784-8671.25.08001-6","url":null,"abstract":"<p><p>Atopic dermatitis involves the head and neck area across all age groups. This manifestation is frequently referred to as \"the head and neck dermatitis.\" Aside from a considerable deterioration of the quality of life, it poses a significant diagnostic and therapeutic challenge. The head and neck dermatitis may be mimicked by other inflammatory conditions such as seborrheic dermatitis or contact dermatitis. Furthermore, it can be associated with a wide range of infectious, ocular, psychiatric and hair disorders, which should raise clinical alertness and encourage a multidisciplinary management of the affected individuals. Skin lesions in the head and neck area are often difficult to treat, particularly because of a considerable exposure of this region to exacerbating factors and limitations regarding the use of some pharmaceuticals. Although several hypotheses explaining the recalcitrant course of head and neck dermatitis have been proposed, none of them provide successful solutions applicable in the daily clinical practice. This comprehensive review comprises the current insights on the pathogenesis, clinical presentation, and comorbidities of the head and neck dermatitis. Recommendations regarding possible treatments of this condition such as antifungals, as well as special considerations for the choice of biologics or JAK inhibitors in the candidates for systemic treatment are outlined.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":"160 2","pages":"123-144"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marco Ardigò, Leonardo Flenghi, Adalberto Ibatici, Cesare Massone, Pietro Quaglino, Miriam Teoli, Chandrakala Toldo, Tommasina Perrone, Alessandra Tucci, Stefano Caccavale, Pier L Zinzani
{"title":"Cutaneous T-cell lymphomas: a real-life experience of anticipated use of mogamulizumab in Italy.","authors":"Marco Ardigò, Leonardo Flenghi, Adalberto Ibatici, Cesare Massone, Pietro Quaglino, Miriam Teoli, Chandrakala Toldo, Tommasina Perrone, Alessandra Tucci, Stefano Caccavale, Pier L Zinzani","doi":"10.23736/S2784-8671.25.08110-1","DOIUrl":"10.23736/S2784-8671.25.08110-1","url":null,"abstract":"<p><p>Mogamulizumab is a humanized monoclonal antibody with enhanced antibody-dependent cell-mediated cytotoxicity that targets chemokine receptor type. Several clinical trials and real-life experiences confirmed the efficacy and safety profiles of mogamulizumab as second-line therapy and beyond, and the biochemical- and dermatology-specific quality of life and physical functioning, with high treatment satisfaction. Systemic drugs are usually used in patients with resistant or advanced forms of cutaneous T-cell lymphomas (especially mycosis fungoides) or with Sézary Syndrome, while early-stage mycosis fungoides can be managed at least initially with local treatments. The most recent Guidelines confirm this approach, but recommend also an anticipated use (starting from the second line) of new therapeutic agents in advanced skin lymphomas. In this report, we discuss eight cases of patients with mycosis fungoides or Sézary Syndrome successfully managed with an anticipated use of mogamulizumab in real-life clinical practice in Italy.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"97-108"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alba Navarro-Bielsa, Manuel Almenara-Blasco, Tamara Gracia-Cazaña, Ignacio Ros, Carmen Gomez Mateo, Pedro Gil-Pallares, Yolanda Gilaberte
{"title":"Paradoxical psoriasiform eruption in pediatric patients with inflammatory bowel disease treated with adalimumab.","authors":"Alba Navarro-Bielsa, Manuel Almenara-Blasco, Tamara Gracia-Cazaña, Ignacio Ros, Carmen Gomez Mateo, Pedro Gil-Pallares, Yolanda Gilaberte","doi":"10.23736/S2784-8671.24.08030-7","DOIUrl":"10.23736/S2784-8671.24.08030-7","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"179-181"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucia Peterle, Laura Macca, Federico Vaccaro, Francesco Borgia, Michele Gaeta, Maria Lentini, Mario Vaccaro
{"title":"Sarcoidosis-like reaction induced by dupilumab.","authors":"Lucia Peterle, Laura Macca, Federico Vaccaro, Francesco Borgia, Michele Gaeta, Maria Lentini, Mario Vaccaro","doi":"10.23736/S2784-8671.24.07854-X","DOIUrl":"10.23736/S2784-8671.24.07854-X","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"172-173"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Federica Filippi, Francesco P Salamone, Alice N Rossi, Lidia Sacchelli, Bianca M Piraccini, Federico Bardazzi
{"title":"A case of trigeminal trophic syndrome.","authors":"Federica Filippi, Francesco P Salamone, Alice N Rossi, Lidia Sacchelli, Bianca M Piraccini, Federico Bardazzi","doi":"10.23736/S2784-8671.24.08123-4","DOIUrl":"10.23736/S2784-8671.24.08123-4","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"190-192"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carolina Donelli, Cristiana Barreca, Laura Calabrese, Pietro Rubegni, Laura Lazzeri
{"title":"Belimumab as a potential therapeutic option for bullous systemic lupus erythematosus.","authors":"Carolina Donelli, Cristiana Barreca, Laura Calabrese, Pietro Rubegni, Laura Lazzeri","doi":"10.23736/S2784-8671.24.08057-5","DOIUrl":"10.23736/S2784-8671.24.08057-5","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"182-183"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Edoardo Mortato, Giorgia Sbarra, Riccardo Viola, Alexandre R Meduri, Felice Primavera, Francesco Loconsole
{"title":"Efficacy and safety of treatment with biological drugs in psoriasis patients with a history of malignancies: a single-center observational study.","authors":"Edoardo Mortato, Giorgia Sbarra, Riccardo Viola, Alexandre R Meduri, Felice Primavera, Francesco Loconsole","doi":"10.23736/S2784-8671.25.08035-1","DOIUrl":"10.23736/S2784-8671.25.08035-1","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"181-182"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eleonora DI Michele, Andrea DI Buduo, Italo F Aromolo, Michele Parietti, Elisa Robustelli Test, Angelo V Marzano, Paolo Sena, Pamela Vezzoli
{"title":"IgA pemphigus following SARS-Cov-2 vaccine.","authors":"Eleonora DI Michele, Andrea DI Buduo, Italo F Aromolo, Michele Parietti, Elisa Robustelli Test, Angelo V Marzano, Paolo Sena, Pamela Vezzoli","doi":"10.23736/S2784-8671.25.07995-2","DOIUrl":"https://doi.org/10.23736/S2784-8671.25.07995-2","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":"160 2","pages":"176-177"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}