Italian Journal of Dermatology and Venereology最新文献_第8页

Estimates of the burden of skin melanoma in Italy: update to 2024. 意大利皮肤黑色素瘤负担估计：更新至2024年。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2025-01-22 DOI: 10.23736/S2784-8671.24.08033-2

Emanuele Crocetti, Federica Zamagni, Fabio Falcini, Rosa Vattiato, Flavia Baldacchini, Chiara Balducci, Orietta Giuliani, Silvia Mancini, Alessandra Ravaioli, Benedetta Vitali, Lauro Bucchi

{"title":"Estimates of the burden of skin melanoma in Italy: update to 2024.","authors":"Emanuele Crocetti, Federica Zamagni, Fabio Falcini, Rosa Vattiato, Flavia Baldacchini, Chiara Balducci, Orietta Giuliani, Silvia Mancini, Alessandra Ravaioli, Benedetta Vitali, Lauro Bucchi","doi":"10.23736/S2784-8671.24.08033-2","DOIUrl":"10.23736/S2784-8671.24.08033-2","url":null,"abstract":"Background: The epidemiology of skin melanoma (SM) is rapidly changing. Therefore, we aimed at updating up to 2024 the Italian estimates on SM providing the number of incident and prevalent cases, the deaths and the distribution by stage at diagnosis.Methods: Incidence was extrapolated from age- and sex-specific International Agency for Research on Cancer (IARC) estimates from 2022 to 2025. For mortality, we applied to the most recent observed deaths, the average sex- and age-specific annual percent change estimated by the IARC from 2022 to 2025. Regarding SM prevalence, we assumed the age- and sex-specific annual change in the number of prevalent cases observed from 2010 to 2020 to be stable until 2024. Finally, we applied the average distribution by TNM-8 stages of four population-based SM series to provide a possible stage distribution at diagnosis.Results: We estimated almost 13,800 newly diagnosed SMs (54% men and 82% people older than 44 years), 2240 deaths (60% men and 49% people older than 74 years) and about 216,000 prevalent cases (51% women). At diagnosis, around 10,240 cases are expected to be stage I, 2120 stage II, 1100 stage III and 327 stage IV. As regards stage I 79% will be IA. Among stage II we expect 44% IIA, 33% IIB and 22% IIC. Among stage III, 49% case are expected to be IIIC.Conclusions: These estimates allow clinicians and policymakers to quantify and properly address the burden of SM patients' diagnostic, therapeutic and supportive needs.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"1-6"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Angioedema-like allergic contact dermatitis in a pediatric patient due to an eyebrows dye. 一名儿童患者因染眉剂引发血管性水肿样过敏性接触性皮炎。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2024-11-04 DOI: 10.23736/S2784-8671.24.07977-5

Lorenzo Melloni, Federico Gianessi, Chiara Bocchi, Elisa Marzola, Alessandro Borghi, Monica Corazza

引用次数: 0

Nummular eczema following brigatinib administration in patient with lung cancer. 肺癌患者服用布加替尼后出现丘疹性湿疹。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2024-11-04 DOI: 10.23736/S2784-8671.24.08002-2

Maria E Greco, Simone Michelini, Emanuele Amore, Antonio DI Guardo, Vito V Gomes, Luca Guarino, Francesca P Sasso, Federica Trovato, Giovanni Pellacani

引用次数: 0

Tuscany consensus for pediatric scabies: update on clinical management and the urgent need for new guidelines. 托斯卡纳小儿疥疮共识：临床管理的最新进展和对新指南的迫切需求。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2024-11-19 DOI: 10.23736/S2784-8671.24.07991-X

Andrea Bassi, Michela Magnano, Cesare Filippeschi, Samantha Berti, Laura Bachini, Martina Vispi, Camilla Peccianti, Giordana Coronella, Teresa Oranges, Carlo Mazzatenta

{"title":"Tuscany consensus for pediatric scabies: update on clinical management and the urgent need for new guidelines.","authors":"Andrea Bassi, Michela Magnano, Cesare Filippeschi, Samantha Berti, Laura Bachini, Martina Vispi, Camilla Peccianti, Giordana Coronella, Teresa Oranges, Carlo Mazzatenta","doi":"10.23736/S2784-8671.24.07991-X","DOIUrl":"10.23736/S2784-8671.24.07991-X","url":null,"abstract":"Background: The aim of this study was to assess the degree of agreement among pediatric dermatologists in Tuscany concerning different aspects of scabies infestation management in children, employing the Delphi method.Methods: We conducted a Delphi study involving ten pediatric dermatology centers in Tuscany, Italy. Questionnaires were distributed to a panel of experts anonymously. The questionnaires were organized into six specific topics: \"diagnosis,\" \"hygiene measures,\" \"application of topical products,\" \"treatment,\" \"treatment of exposed individuals,\" and \"clinical follow-up after therapy.\" Each question within these topics offered six different response options.Results: All participating dermatologists completed the two-round questionnaire. Full consensus was reached for all statements related to \"diagnosis,\" \"hygiene measures,\" \"treatment of exposed individuals,\" \"application of topical products,\" and \"clinical follow-up after therapy,\" since each statement met the predetermined consensus threshold of 70% or higher. However, we could not achieve a substantial consensus on the treatment of scabies, aside from agreement on the lower efficacy of permethrin therapy.Conclusions: Considering the growing recognition of Sarcoptes scabiei resistance to conventional permethrin therapy, this regional consensus offers clear insights into the overall management of scabies. However, it also reveals that each dermatologist primarily relies on their own experiences for medical treatment, which may not be universally shared among colleagues. This emphasizes the urgent necessity for updated guidelines on therapeutic strategies.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"12-19"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142668068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel transethosome coencapsulated combination for acne treatment: in-vitro efficacy and ex-vivo biodistribution studies. 新型转酶体共包合治疗痤疮：体外疗效和体外生物分布研究。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 DOI: 10.23736/S2784-8671.24.07982-9

Alfredo Martinez-Gutierrez, Javier Sendros, Teresa Noya, Mari C González

{"title":"Novel transethosome coencapsulated combination for acne treatment: in-vitro efficacy and ex-vivo biodistribution studies.","authors":"Alfredo Martinez-Gutierrez, Javier Sendros, Teresa Noya, Mari C González","doi":"10.23736/S2784-8671.24.07982-9","DOIUrl":"10.23736/S2784-8671.24.07982-9","url":null,"abstract":"Background: Acne vulgaris is a skin condition affecting approximately 85% of young adults. It is influenced by androgens and primarily occurs in the pilosebaceous unit, where inflammation and obstruction happen. Hyperseborrhea and hyperkeratinization lead to increased levels of fatty acids and necrotic keratinocytes, promoting the proliferation of C. acnes phylotype IA1.Methods: Here, the in-vitro efficacy of a novel combination on the main processes involved in acne was studied. Furthermore, the combination was coencapsulated in transethosomes to target the pilosebaceous unit, and the biodistribution was analyzed ex vivo by fluorescence microscopy.Results: The combination of compounds reduced inflammatory markers levels, sebum production and 5α-Reductase levels while it induced autophagy and FOXO1 nuclear levels in sebocytes. The compounds coencapsulated in transethosomes reached the pilosebaceous unit as proven by the ex vivo analysis.Conclusions: The proposed combination of compounds is a promising approach to be included in topical products for the treatment of acne vulgaris.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":"160 1","pages":"7-11"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New onset vitiligo induced by dupilumab therapy for severe asthma: a case report and a short review of the literature. dupilumab治疗严重哮喘引起的新发白癜风：一个病例报告和简短的文献回顾。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2024-11-29 DOI: 10.23736/S2784-8671.24.07987-8

Giulia Bazzacco, Filippo Chersi, Enrico Zelin, Vanessa Mazzoletti, Nicola DI Meo, Iris Zalaudek, Raffaele D Caposiena Caro

引用次数: 0

Prurigo pigmentosa and bariatric surgery: not a simple coincidence. 色素性瘙痒症与减肥手术：并非巧合。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2024-11-04 DOI: 10.23736/S2784-8671.24.07961-1

Eleonora Natale, Elia Esposto, Edoardo Cammarata, Federica Veronese, Andrea Carletti, Jacopo Colombo, Carlotta Melotti, Elisa Zavattaro, Paola Savoia

引用次数: 0

Dupilumab facial redness induced by Rhodotorula mucilaginosa infection. 粘膜红斑癣菌感染引起的杜比卢单抗面部发红。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2024-11-19 DOI: 10.23736/S2784-8671.24.08021-6

Elia Esposto, Federica Veronese, Edoardo Cammarata, Paola Savoia

引用次数: 0

Coexistence of psoriasis vulgaris and lichen planus pemphigoids in an elderly patient. 寻常型银屑病和类天疱疮扁平苔藓共存的老年患者。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2024-11-29 DOI: 10.23736/S2784-8671.24.08011-3

Dario Didona, Julia Hinterseher, Antonio M Sequeira Santos, Michael Hertl

引用次数: 0

Update on the role of color Doppler ultrasound in hidradenitis suppurativa: a game-changer. 彩色多普勒超声在化脓性扁桃体炎中的最新作用：改变游戏规则。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2024-11-19 DOI: 10.23736/S2784-8671.24.08025-3

Ximena Wortsman

{"title":"Update on the role of color Doppler ultrasound in hidradenitis suppurativa: a game-changer.","authors":"Ximena Wortsman","doi":"10.23736/S2784-8671.24.08025-3","DOIUrl":"10.23736/S2784-8671.24.08025-3","url":null,"abstract":"Hidradenitis suppurativa has greatly benefited from the insights of color Doppler ultrasound. Thus, ultrasonography has helped prove the follicular link of this disease and has ruled out the primary involvement of the apocrine glands, which, in the old days, was supposedly the cause of the disease. Importantly, ultrasound can detect subclinical anatomical information in HS that cannot be deducted from the clinical examination. Moreover, high-frequency (≥15 MHz) and ultra-high-frequency (≥50 MHz) ultrasound present a much higher axial spatial resolution compared to magnetic resonance imaging. Ultrasound allows us to detect better subclinical cutaneous anatomical abnormalities and, therefore, arrive earlier and more accurately at diagnosis and staging. Ultrasonographic diagnostic criteria can discriminate HS from other clinical simulators, which is also critical in diagnosing mild and moderate stages and is relevant for the severe stages. This imaging technique supports the severity (mSOS-HS) and activity (US-HSA) scorings more accurately, which can help assess the actual stage of the disease. This is important to decide the type of treatment and to perform a more objective follow-up of the patients. Magnetic resonance imaging has been reported as helpful in diagnosing deep perianal tunnels; however, it presents a lower axial spatial resolution compared with high and ultra-high frequency ultrasound. Nowadays, there is solid evidence of the usefulness of ultrasound in HS, which implies that it is a game-changer and should be recommended as the first-choice imaging technique and a standard of care tool for HS patients.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"55-63"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142668070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0