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Drug associated bullous pemphigoid: what's new?
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2024-12-01 DOI: 10.23736/S2784-8671.24.07907-6
Efthymia Soura, Maria Gerochristou, Theodora Douvali, Vassiliki Chasapi, Alexander Stratigos
{"title":"Drug associated bullous pemphigoid: what's new?","authors":"Efthymia Soura, Maria Gerochristou, Theodora Douvali, Vassiliki Chasapi, Alexander Stratigos","doi":"10.23736/S2784-8671.24.07907-6","DOIUrl":"10.23736/S2784-8671.24.07907-6","url":null,"abstract":"<p><p>Bullous pemphigoid (BP) is considered to be one of the most common autoimmune diseases affecting the skin. Drug associated BP (DABP) is a subset of BP that is caused by the ingestion of specific types of medications. Until this point more than 80 medications have been associated with this condition that only recently has started to be better described. DABP has a better clinical course and prognosis compared to that of idiopathic BP, especially when the suspected inciting medication is discontinued in a timely manner. Therefore, it is very important to obtain detailed medical histories from BP patients especially if they are receiving multiple medications and also to be vigilant for subtle, but important, indications in histopathological, ELISA and immunofluorescence findings as well as in the clinical manifestations of the disorder.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":"159 6","pages":"626-637"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extragenital syphiloma on the palmar region in a patient with atopic dermatitis.
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2024-12-01 DOI: 10.23736/S2784-8671.24.08076-9
Silvia Borriello, Sergio Delmonte, Caterina Quarta, Nicole Macagno, Luca Mastorino, Simone Ribero, Pietro Quaglino
{"title":"Extragenital syphiloma on the palmar region in a patient with atopic dermatitis.","authors":"Silvia Borriello, Sergio Delmonte, Caterina Quarta, Nicole Macagno, Luca Mastorino, Simone Ribero, Pietro Quaglino","doi":"10.23736/S2784-8671.24.08076-9","DOIUrl":"https://doi.org/10.23736/S2784-8671.24.08076-9","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":"159 6","pages":"687-688"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biosimilars for the treatment of psoriasis: a narrative review.
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2024-12-01 DOI: 10.23736/S2784-8671.24.08083-6
Duc B Phan, Zenas Z Yiu
{"title":"Biosimilars for the treatment of psoriasis: a narrative review.","authors":"Duc B Phan, Zenas Z Yiu","doi":"10.23736/S2784-8671.24.08083-6","DOIUrl":"https://doi.org/10.23736/S2784-8671.24.08083-6","url":null,"abstract":"<p><p>The introduction of systemic biologic therapies marked a significant advancement in the treatment of moderate to severe psoriasis. However, the high cost associated with these treatments has considerably restricted their widespread utilization. The expiration of biologic patents has allowed the development of biosimilars - medications that are highly similar to approved biologics. Biosimilars hold the promise of reducing treatment costs, thereby enhancing patient access to biologic therapies and contributing to the sustainability of healthcare spending. Nonetheless, the unique regulatory pathways for biosimilars introduce uncertainties regarding their application in real-world psoriasis care. Adoption and regulation of biosimilars differ considerably across countries, reflecting diverse approaches and priorities within global healthcare systems. Potential variations between biosimilars and their originator biologics raise questions about their comparative effectiveness and safety. Current evidence supporting biosimilars for psoriasis treatment is largely based on a limited number of randomized controlled trials (RCTs), with a notable lack of robust real-world evidence. As more biosimilars enter the market, evaluating their use in real-world settings is crucial to identify any differences in effectiveness and safety compared to originators or to enhance their uptake by improving the perceptions of physicians and patients. This review explores the opportunities and challenges presented by biosimilars and underscores the existing gaps in evidence regarding their use in psoriasis treatment.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":"159 6","pages":"663-675"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Noninvasive imaging to diagnose neurofibroma mimicking basal cell carcinoma: dermoscopy, reflectance confocal microscopy and line-field confocal optical coherence tomography. 诊断模仿基底细胞癌的神经纤维瘤的无创成像技术：皮肤镜、反射共聚焦显微镜和线场共聚焦光学相干断层扫描。
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2024-11-29 DOI: 10.23736/S2784-8671.24.08080-0
Giulio Cortonesi, Vittoria Cioppa, Emanuele Trovato, Lorenzo Barbarossa, Pietro Rubegni, Elisa Cinotti
{"title":"Noninvasive imaging to diagnose neurofibroma mimicking basal cell carcinoma: dermoscopy, reflectance confocal microscopy and line-field confocal optical coherence tomography.","authors":"Giulio Cortonesi, Vittoria Cioppa, Emanuele Trovato, Lorenzo Barbarossa, Pietro Rubegni, Elisa Cinotti","doi":"10.23736/S2784-8671.24.08080-0","DOIUrl":"https://doi.org/10.23736/S2784-8671.24.08080-0","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current landscape and future perspectives in the pathogenesis and treatment of Pyoderma gangrenosum. 坏疽性脓皮病的发病机制和治疗的现状和未来展望。
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2024-11-29 DOI: 10.23736/S2784-8671.24.08010-1
Sarah L Becker, Alex G Ortega-Loayza
{"title":"Current landscape and future perspectives in the pathogenesis and treatment of Pyoderma gangrenosum.","authors":"Sarah L Becker, Alex G Ortega-Loayza","doi":"10.23736/S2784-8671.24.08010-1","DOIUrl":"https://doi.org/10.23736/S2784-8671.24.08010-1","url":null,"abstract":"<p><p>Pyoderma gangrenosum is a rare, ulcerative neutrophilic dermatosis of yet unknown origin. While advances have been made into the mechanisms underlying PG, our understanding is limited by a paucity of research and funding into this condition. This review highlights the current landscape of PG pathogenesis, diagnosis, and treatment in the hopes of encouraging additional scientific inquiry into this rare, severe condition.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lichen striatus: a review. 纹状地衣：综述。
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2024-10-03 DOI: 10.23736/S2784-8671.24.07998-2
Astrid Herzum, Gianmaria Viglizzo, Corrado Occella, Lodovica Gariazzo, Valerio G Vellone, Silvia M Orsi, Giulia Ciccarese
{"title":"Lichen striatus: a review.","authors":"Astrid Herzum, Gianmaria Viglizzo, Corrado Occella, Lodovica Gariazzo, Valerio G Vellone, Silvia M Orsi, Giulia Ciccarese","doi":"10.23736/S2784-8671.24.07998-2","DOIUrl":"10.23736/S2784-8671.24.07998-2","url":null,"abstract":"<p><strong>Introduction: </strong>Lichen striatus (LS) is an acquired blaschkitis, with typical linear and unilateral distribution. It occurs mainly in children and is self-resolving, yet its etiopathogenesis remains widely unknown.</p><p><strong>Evidence acquisition: </strong>A review of the literature on LS cases was performed using the keyword \"lichen striatus\" to retrieve all relevant articles through PubMed and Google Scholar.</p><p><strong>Evidence synthesis: </strong>A total of 27 articles describing 440 LS patients were included in the present review. Mean age of patients was 3.8 years; male: female: ratio was 1:1.9. The present review confirms LS as a primarily pediatric condition, mainly affecting females. Dysregulation of the immune system might be involved in its pathogenesis, with cytotoxic T-cells attacking mosaic keratinocytes after loss of immune tolerance. The review confirms LS is mainly diagnosed clinically (80%) based on its clinical characteristics: erythematous (70%) or hypopigmented (24%) papules, distributed along the lines of Blashko. The benignity of this clinical entity is suggested by the rather short duration of disease (9.5 months on average) and by the uncommonness of therapy, adopted in only 20% of cases, and when needed, administered topically.</p><p><strong>Conclusions: </strong>This review examines the complexities of LS but acknowledges limitations in data sources and calls for further research.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coping style and psychopathological morbidity in patients with advanced melanoma: differences between cancer therapy, metastatic location and staging. 晚期黑色素瘤患者的应对方式和心理病理学发病率：癌症治疗、转移位置和分期之间的差异。
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2024-10-01 DOI: 10.23736/S2784-8671.24.07759-4
Bernardo Carli, Raffaella Grifoni, Elisabetta Surrenti, Lucia Caligiani, Lorenzo Borgognoni, Nicola Pimpinelli
{"title":"Coping style and psychopathological morbidity in patients with advanced melanoma: differences between cancer therapy, metastatic location and staging.","authors":"Bernardo Carli, Raffaella Grifoni, Elisabetta Surrenti, Lucia Caligiani, Lorenzo Borgognoni, Nicola Pimpinelli","doi":"10.23736/S2784-8671.24.07759-4","DOIUrl":"https://doi.org/10.23736/S2784-8671.24.07759-4","url":null,"abstract":"<p><strong>Background: </strong>The incidence of melanoma has been steadily increasing in recent years and remains one of the most frequent cancers in adolescents and young adults. The literature shows how a high percentage of melanoma patients present with high anxiety and depression scores and a correlation between worsening quality of life and impaired body image has been shown. The present study aimed to investigate the relationship between cutaneous and visceral metastasis in a group of 73 patients with advanced melanoma in relation to body image, anxiety, depression, and coping style.</p><p><strong>Methods: </strong>Hospital Anxiety and Depression Scale, Body Image Scale and Mini-Mac questionnaires were administered to a sample of 73 subjects with advanced melanoma (stage III and IV); Analyses were performed with SPSS version 28.01 and a P value <0.05 was considered significant.</p><p><strong>Results: </strong>Emerging results indicated greater body image impairment in patients with skin metastasis, no significant difference in anxiety and depression by staging. Patients receiving target therapy showed a reduction in anxiety and depression compared with patients receiving immunotherapy.</p><p><strong>Conclusions: </strong>In line with the literature, cutaneous metastatic involvement negatively affected body image, a prevalence rate of anxiety and depression of 28,8% and 19.2%, respectively, emerged in the sample, while 17.8% reported significant body image impairment, suggesting how melanoma impacts in patient's quality of life.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":"159 5","pages":"513-520"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dermanyssus gallinae dermatitis in a young Italian woman. 一名意大利年轻女性的 Dermanyssus gallinae 皮炎。
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2024-10-01 Epub Date: 2024-08-02 DOI: 10.23736/S2784-8671.24.07905-2
Sara Lambiase, Giuseppe Cianchini, Enrico Matteini, Fabio Artosi, Antonia Rivieccio, Francesco M Bonacci, Luca Bianchi, Elena Campione
{"title":"Dermanyssus gallinae dermatitis in a young Italian woman.","authors":"Sara Lambiase, Giuseppe Cianchini, Enrico Matteini, Fabio Artosi, Antonia Rivieccio, Francesco M Bonacci, Luca Bianchi, Elena Campione","doi":"10.23736/S2784-8671.24.07905-2","DOIUrl":"10.23736/S2784-8671.24.07905-2","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"593-595"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141874810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overlap of psoriasis and atopic dermatitis in patients with comorbidities: a difficult therapeutic challenge. 合并症患者中银屑病和特应性皮炎的重叠：治疗难题。
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2024-10-01 Epub Date: 2024-08-02 DOI: 10.23736/S2784-8671.24.07937-4
Silvia Gerosa, Maria B DE Felici Del Giudice, Stefano Macchi, Claudio Feliciani, Francesca Satolli
{"title":"Overlap of psoriasis and atopic dermatitis in patients with comorbidities: a difficult therapeutic challenge.","authors":"Silvia Gerosa, Maria B DE Felici Del Giudice, Stefano Macchi, Claudio Feliciani, Francesca Satolli","doi":"10.23736/S2784-8671.24.07937-4","DOIUrl":"10.23736/S2784-8671.24.07937-4","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"586-587"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141874813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapid involution of a melanocytic lesion with peripheral globules. 黑色素细胞病变迅速消退，外周出现球状物。
IF 1.8 4区 医学
Italian Journal of Dermatology and Venereology Pub Date : 2024-10-01 Epub Date: 2024-06-20 DOI: 10.23736/S2784-8671.24.07918-0
Emmanouil Chousakos, Marcella Grassi, Simone Ribero
{"title":"Rapid involution of a melanocytic lesion with peripheral globules.","authors":"Emmanouil Chousakos, Marcella Grassi, Simone Ribero","doi":"10.23736/S2784-8671.24.07918-0","DOIUrl":"10.23736/S2784-8671.24.07918-0","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"575-576"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141431954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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