Italian Journal of Dermatology and Venereology最新文献_第7页

Epcoritamab injection site skin eruption: a frequent yet unharmful effect due to a local delayed reaction mechanism. 依可瑞单抗注射部位皮肤出疹：由于局部延迟反应机制导致的频繁但无害的效果。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-04-01 Epub Date: 2025-02-25 DOI: 10.23736/S2784-8671.25.08061-2

Corrado Zengarini, Martina Mussi, Silva Robuffo, Giammarco Bagnato, Cinzia Pellegrini, Pier L Zinzani, Bianca M Piraccini, Alessandro Pileri

引用次数: 0

Malar bags: clinical features and therapeutic options. 马拉尔袋：临床特征和治疗选择。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-03-19 DOI: 10.23736/S2784-8671.25.08098-3

Benedetta Fanelli, Giorgio Maullu, Maria G Onesti, Nicolò Scuderi

{"title":"Malar bags: clinical features and therapeutic options.","authors":"Benedetta Fanelli, Giorgio Maullu, Maria G Onesti, Nicolò Scuderi","doi":"10.23736/S2784-8671.25.08098-3","DOIUrl":"https://doi.org/10.23736/S2784-8671.25.08098-3","url":null,"abstract":"Malar bags are a common aesthetic concern characterized by swelling and puffiness in the prezygomatic space and cheek area. Various medical and surgical techniques have been developed to address this condition and restore a more youthful and rejuvenated appearance. In terms of medical therapies, non-invasive options such as topical creams containing retinoids, peptides, and hyaluronic acid have shown promise in reducing mild malar bags. These substances help improve skin texture, promote collagen production, and enhance skin elasticity, thereby reducing the appearance of swelling and puffiness. Additionally, injectable treatments such as dermal fillers have been utilized to camouflage malar bags and create a smoother contour. By strategically placing fillers in the surrounding areas, a skilled practitioner can achieve a more harmonious facial appearance. In recent years, advancements in radiofrequency have also shown promise for treating malar bags. Laser skin resurfacing procedures can help tighten the skin, stimulate collagen production, and reduce the appearance of swelling and wrinkles in the malar area. For patients seeking more lasting results, surgical techniques provide viable options. Blepharoplasty, a surgical procedure aimed at correcting eyelid issues, can be performed to remove excess skin and fat deposits in the lower eyelid, effectively addressing malar bags. Additionally, newer techniques like endoscopic surgery allow for minimal incisions and reduced scarring, making them appealing to patients concerned about visible postoperative marks. Although numerous medical and surgical techniques are available, the choice of treatment depends on factors such as the severity of the condition, patient preferences, and the expertise of the medical practitioner. In this manuscript we have made a retrospective evaluation of the medical and surgical therapies of malar bags and we report our considerations after 20 years of experience.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trends in Breslow thickness of nodular and superficial spreading melanoma subtypes and associated factors: a twelve-year analysis from a tertiary referral center in Greece. 结节性和浅表扩散黑色素瘤亚型的brreslow厚度趋势及相关因素：来自希腊三级转诊中心的12年分析。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2025-01-22 DOI: 10.23736/S2784-8671.24.08129-5

Aikaterini Niforou, Pagona D Lagiou, Alan C Geller, Nick Dessypris, Alexander J Stratigos

{"title":"Trends in Breslow thickness of nodular and superficial spreading melanoma subtypes and associated factors: a twelve-year analysis from a tertiary referral center in Greece.","authors":"Aikaterini Niforou, Pagona D Lagiou, Alan C Geller, Nick Dessypris, Alexander J Stratigos","doi":"10.23736/S2784-8671.24.08129-5","DOIUrl":"10.23736/S2784-8671.24.08129-5","url":null,"abstract":"Background: Primary tumor thickness is important for prognosis of melanoma patients. To enhance prevention and quantify the true burden of melanoma, better understanding of thickness patterns and associated characteristics is crucial. Previous studies have been limited to report trends and address risk factors of thickness in specific melanoma subtypes in the Greek population. We investigated associations between epidemiological characteristics and thickness for the two most common melanoma subtypes and the trends in thickness over a twelve-year period.Methods: A retrospective study of 1201 patients with histologically confirmed primary nodular and superficial spreading melanoma (SSM) diagnosed from 2010 to 2021 in \"Andreas Sygros\" Hospital of Cutaneous and Venereal diseases was conducted. Multiple regression was performed to examine the association of variables of interest with melanoma thickness.Results: SSM thickness significantly increased by 2% per year (percent of change: 2.0, 95% CI: 0.2, 3.7) from 2010 to 2021, while a similar tendency for nodular melanoma (NM) thickness was indicated. Age at diagnosis was demonstrated to be a predictor of thickness for both subtypes. When considering all confounders, overall sun exposure was inversely associated with SSM thickness (PC: -6.2, 95% CI: -12.4, 0.5) and a similar association was indicated for NM (PC: -9.3, 95%CI: -21.1, 4.2).Conclusions: These results indicate an upward trend of SSM thickness and the associations of age at diagnosis and overall exposure to UV with thickness of both subtypes. Future research is needed to identify additional characteristics and explain differences among all melanoma types.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"20-28"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Angiolymphoid hyperplasia with eosinophilia of the ear. 耳朵血管淋巴细胞增生伴嗜酸性粒细胞增多。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2024-11-04 DOI: 10.23736/S2784-8671.24.07966-0

Federica Li Pomi, Federico Vaccaro, Antonio Ieni, Francesco Borgia, Mario Vaccaro

引用次数: 0

Juvenile gangrenous vasculitis of the scrotum: a rare entity and a diagnostic challenge. 阴囊的少年坏疽性血管炎：一个罕见的实体和诊断的挑战。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2024-12-17 DOI: 10.23736/S2784-8671.24.08029-0

Barbara Cocuroccia, Giorgio Annessi, Enzo Palese, Siavash Rahimi, Filomena Russo

引用次数: 0

The emerging role of photodynamic therapy in the treatment of cutaneous infections. 光动力疗法在皮肤感染治疗中的新作用。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2024-11-29 DOI: 10.23736/S2784-8671.24.07910-6

Olive Anagu, Jesse Salas, Sarah Choe, Abhinav Birda, Ajay Sharma, Gabrielle Baker, Natasha Mesinkovska

{"title":"The emerging role of photodynamic therapy in the treatment of cutaneous infections.","authors":"Olive Anagu, Jesse Salas, Sarah Choe, Abhinav Birda, Ajay Sharma, Gabrielle Baker, Natasha Mesinkovska","doi":"10.23736/S2784-8671.24.07910-6","DOIUrl":"10.23736/S2784-8671.24.07910-6","url":null,"abstract":"Introduction: Cutaneous infections pose ongoing challenges to standard treatments due to resistance and limited efficacy. Photodynamic therapy (PDT) emerges as a promising supplement or an alternative to address complicated cases. In this review, we comprehensively review PDT's safety and efficacy in treating cutaneous infections.Evidence acquisition: A PubMed systematic review with search terms for PDT treatment, hair, skin, and nail infections.Evidence synthesis: There were a total of 43 studies on the use of PDT in cutaneous infections which discussed the treatment of viral (N.=20), bacterial (N.=11), fungal (N.=9), and protozoal (N.=3) infections. There is evidence for using PDT, mostly 5-aminolevulinic acid (5-ALA) and methyl aminolevulinate (MAL), in the treatment of cutaneous infections. Most evidence for viral infections involved treatment with 5-ALA PDT in condyloma acuminatum (CoAc), verruca vulgaris, and molluscum contagiosum. In bacterial infections, 5-ALA and MB PDT have been used to achieve complete remission in refractory Pseudomonas and atypical mycobacteria infections without recurrence. In onychomycosis, MAL PDT achieved a 40.9% cure rate and MB PDT showed a 77.8-100% cure rate with no reports of recurrence. Parasitic infections, such as leishmaniasis have also been successfully treated with both 5-ALA and MAL PDT.Conclusions: PDT is a promising treatment option for cutaneous infections, with growing evidence for its utility in treating cutaneous bacterial, viral, fungal, and parasitic infections, particularly those that fail standard treatments. Side effects were mostly limited to localized pain with good outcomes and low recurrence rates.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"40-46"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eczematous eruption after ixekizumab successfully treated with upadacitinib. 用upadacitinib成功治疗ixekizumab后的湿疹爆发。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 DOI: 10.23736/S2784-8671.24.08050-2

Martina Burlando, Barbara Piazza, Antonio Guadagno, Emanuele Cozzani

引用次数: 0

The role of intravenous immunoglobulin in autoimmune diseases with dermatological implications. 静脉注射免疫球蛋白在对皮肤有影响的自身免疫性疾病中的作用。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2024-10-03 DOI: 10.23736/S2784-8671.24.07955-6

Antonio Podo Brunetti, Carolina DE Rosa, Vanessa Bottino, Franco Rongioletti

{"title":"The role of intravenous immunoglobulin in autoimmune diseases with dermatological implications.","authors":"Antonio Podo Brunetti, Carolina DE Rosa, Vanessa Bottino, Franco Rongioletti","doi":"10.23736/S2784-8671.24.07955-6","DOIUrl":"10.23736/S2784-8671.24.07955-6","url":null,"abstract":"Intravenous immunoglobulin (IVIG) therapy has emerged as a promising treatment option for various dermatological autoimmune diseases due to its immunomodulatory potential and low incidence of severe side effects. Despite its widespread use, the mechanism of action of IVIG in treating autoimmune diseases remains a topic of debate. IVIG is derived from the plasma fractionation of a large pool of donors, primarily consisting of the IgG isotype. Its main mechanisms of action involve neutralizing circulating autoantibodies via the F(ab')2 portion, inhibiting complement-mediated tissue destruction, and reducing the half-life of circulating autoantibodies through the Fc portion. This paper explores the growing utilization of IVIG as an off-label therapy in dermatological autoimmune or immune-mediated diseases, including autoimmune bullous disease (AIBS), dermatomyositis (DM), lupus erythematosus (LE), systemic sclerosis, scleromyxedema, Stevens-Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN), pyoderma gangrenosum (PG), and necrobiotic xanthogranuloma (NXG). In this context, the sole large prospective, randomized trial was the 2022 ProDERM study, which demonstrate efficacy of IVIG in improving cutaneous manifestations among 95 DM patients compared to the placebo group. Moreover, although considered off-label, the use of IVIG is regarded as the first-line therapy for patients with scleromyxedema. As a first line of therapy, IVIg is only approved for Kawasaki Disease (KD) in the setting of vasculitis. The treatment in all other indications is mostly considered as adjuvant therapy only after failure of immunosuppressive therapy or in the presence of contraindications.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"47-54"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Keloid management: a review of treatment modalities. 瘢痕疙瘩治疗：治疗方法综述。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2024-11-19 DOI: 10.23736/S2784-8671.24.07848-4

Peter M Luo, Donald A Glass Ii

引用次数: 0

Intralesional rifampicin for cutaneous leishmaniosis: a case report with reflectance confocal microscopy therapy assessment. 局部利福平治疗皮肤利什曼病：1例报告与反射共聚焦显微镜治疗评估。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-02-01 Epub Date: 2024-11-29 DOI: 10.23736/S2784-8671.24.07967-2

Giulia Briatico, Gaetano Licata, Vittorio Tancredi, Carmine Fiorentino, Camila Scharf, Francesca Pagliuca, Giuseppe Argenziano, Caterina M Giorgio

引用次数: 0