Italian Journal of Dermatology and Venereology最新文献

{"title":"Diagnostic techniques for demodicosis: a systematic review.","authors":"Patricia Bodas Gallego, Héctor Perandones González","doi":"10.23736/S2784-8671.25.08341-0","DOIUrl":"10.23736/S2784-8671.25.08341-0","url":null,"abstract":"<p><strong>Background: </strong>Demodicosis comprises a spectrum of cutaneous conditions resulting from the overproliferation of Demodex mites. Multiple diagnostic techniques are available, although diagnosis can be challenging due to the presence of these mites as commensals in healthy individuals. Thus, the objective of this review is to evaluate the diagnostic performance of methods used for the diagnosis of demodicosis.</p><p><strong>Methods: </strong>A search was conducted on articles published between 2000 and 2025, using PubMed, Embase, Scopus, Cochrane Library and Dialnet to identify studies on diagnostic methods for cutaneous demodicosis. Of the 1765 records screened, 18 studies met the inclusion criteria, focusing on diagnostic accuracy.</p><p><strong>Results: </strong>A total of 3 cross-sectional, 8 prospective, 3 retrospective, 2 case-control studies and 2 controlled clinical trials have been included. These studies evaluated the diagnostic performance of standardized skin surface biopsy, direct microscopic examination, dermoscopy, reflectance confocal microscopy and molecular techniques in a combined population of 2187 patients. Direct microscopic examination and dermoscopy have been the most frequently used techniques in the enrolled studies. Among the genetic techniques, next-generation sequencing and polymerase chain reaction have been assessed. To our knowledge, this is the first systematic review dealing with diagnostic methods for demodicosis.</p><p><strong>Conclusions: </strong>Due to the heterogeneity of the included studies, identifying an optimal diagnostic method remains challenging. Therefore, diagnostic approaches should be selected according to clinical context and resource availability.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"197-209"},"PeriodicalIF":2.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147673503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rigenase®/polyhexanide cream versus topical antibiotics in preventing postoperative skin superinfections in office dermatologic surgery: preliminary results from a multicenter observational study.","authors":"Maria R Nasca, Giuseppe Micali, Francesco Caudullo, Alessandra Scilletta, Stefano Veraldi","doi":"10.23736/S2784-8671.26.08392-1","DOIUrl":"10.23736/S2784-8671.26.08392-1","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"295-297"},"PeriodicalIF":2.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147433013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutaneous endometriosis mimicking dermatofibrosarcoma protuberans: a dermoscopic pitfall.","authors":"Nello Tommasino, Federica Feo, Rosaria Cappiello, Massimo Mascolo, Francesco Cillo, Alessia Villani, Claudia Costa","doi":"10.23736/S2784-8671.26.08464-1","DOIUrl":"10.23736/S2784-8671.26.08464-1","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"309-310"},"PeriodicalIF":2.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147467981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-world effectiveness of risankizumab in psoriasis: first Sardinian multicenter 2-year experience.","authors":"Grazia Vivanet, Giacomo Bertolino, Cristina Mugheddu, Gabriele Biondi, Gianmario Addis, Giovanni M Carcassi, Pietro Aste, Rosanna Satta, Maria Grazia Mugoni, Elisabetta Scotti, Maria G Atzori, Maria A Montesu, Laura Atzori","doi":"10.23736/S2784-8671.26.08559-2","DOIUrl":"10.23736/S2784-8671.26.08559-2","url":null,"abstract":"<p><strong>Background: </strong>Psoriasis is an immune-mediated chronic skin disease associated with multiple extracutaneous comorbidities, causing a severe quality of life impairment, whose treatment with risankizumab, a humanized anti-IL-23 monoclonal antibody, is very effective, with good safety profile and long-term outcomes. However, prescription in a real-world setting is conditioned by local health care system constraints, as the proven ineffectiveness or appearance of adverse events to first-line drugs. Such delay and selection of multi-failure patients might affect efficacy and outcomes.</p><p><strong>Methods: </strong>A prospective multicenter study, approved by the Ethical Independent Committee of AOU Cagliari, acronym ESSOS-BIO-PSO, Prot N° 2023/2532, was conducted to evaluate risankizumab's effectiveness and safety in Sardinian psoriasis centers over 6, 12, and 24 months.</p><p><strong>Results: </strong>73 patients with moderate-to-severe psoriasis treated with risankizumab over at least 6 months were recruited, predominantly male (70%) with a median age of 50 years and a median disease duration of 22 years. Most patients had extensive, difficult-to-treat areas involved, psoriasis arthritis and other comorbidities. Prior treatments included traditional systemic therapies and biologics (60%). At week 52, 74% achieved PASI-90, increasing to 76.7% at week 104, with all initial PASI-90 responders maintaining the response. Faster and sustained responses were observed in biologic-naïve patients and those with shorter disease duration. The difference between groups was statistically significant at week 16 (Mann-Whitney P=0.042), identifying naïve patients as \"super-responders.\" No severe adverse events occurred; risankizumab was well tolerated and adherence was 100%.</p><p><strong>Conclusions: </strong>This real-world study investigates effectiveness and safety of Risankizumab in a population with a distinctive historical and genetic background, as well as environmental factors which may influence disease patterns and response to treatments. This first Sardinian study confirms durable results with excellent adherence in moderate-to-severe psoriasis patients, regardless of prior treatments and comorbidities burden, although in biologic-naïve patients the response is quicker.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":"161 3","pages":"278-287"},"PeriodicalIF":2.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148301698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Italian dermatology throughout the ages and SIDeMaST today.","authors":"Gianni Angelini, Giuseppe Argenziano, Aurora DE Marco, Maria C Fargnoli, Carlo Gelmetti, Giovanni Pellacani","doi":"10.23736/S2784-8671.26.08599-3","DOIUrl":"10.23736/S2784-8671.26.08599-3","url":null,"abstract":"<p><p>The Italian contribution to the history and development of dermatology and venereology dates back to classical antiquity (5^th century BC). It is extraordinarily rich and diverse, marked by numerous world-renowned scholars, many of whom were pioneers in anatomical-histological and clinical research. Several Italian investigators have lent their names to histological structures and dermatological conditions. Notably, the very first book on dermatology, one of the earliest treatises on venereology, and the first book on cosmetology were all authored by Italians. Italy also established the first dermatological hospital in the world (the Ospedale di Santa Maria e San Gallicano, est. Rome, 1725) entirely dedicated to the treatment of skin diseases, as well as the first scientific journal in the field. This review is divided into two sections. The first traces the historical evolution of Italian dermatology from classical antiquity to the present day. The second focuses on the structure, composition, and objectives of one of the earliest dermatological scientific societies: the Società Italiana di Dermatologia Medica, Chirurgica, Estetica e delle Malattie Sessualmente Trasmesse (SIDeMaST, Italian Society of Medical, Surgical, Aesthetic Dermatology and Sexually Transmitted Diseases), founded in 1885.</p>","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"248-255"},"PeriodicalIF":2.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147698591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First trichogram characterization of hair shaft abnormalities in ichthyosis prematurity syndrome.","authors":"Laura C Gironi, Stephano Cedirian, Lara Camillo, Andrea Zonta, Francesca Zottarelli, Gianluca Landucci, Elia Esposto, Edoardo Cammarata, Pamela Farinelli, Antonio Ramponi, Giovanni Damiani, Antonio Novelli, Elisa Pisaneschi, Bianca M Piraccini, Enrico Colombo, Paola Savoia, Michela Starace","doi":"10.23736/S2784-8671.26.08405-7","DOIUrl":"10.23736/S2784-8671.26.08405-7","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"297-298"},"PeriodicalIF":2.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147390108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe mucositis and fever in a thirteen-year-old girl: Mycoplasma-induced rash and mucositis.","authors":"Filomena Barbato, Gaetano Licata, Eugenia V DI Brizzi, Giulia Manganelli, Raffaele Borrelli, Chiara Tornincasa, Caterina M Giorgio","doi":"10.23736/S2784-8671.26.08261-7","DOIUrl":"10.23736/S2784-8671.26.08261-7","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"288-289"},"PeriodicalIF":2.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147468008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tufted hair folliculitis as an unusual cutaneous manifestation of systemic Langerhans cell histiocytosis.","authors":"Alessandra Rallo, Biagio Didona, Antonio DI Guardo, Camilla Chello, Annunziata Dattola, Steven P Nisticò, Dario Didona","doi":"10.23736/S2784-8671.26.08446-X","DOIUrl":"10.23736/S2784-8671.26.08446-X","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"307-309"},"PeriodicalIF":2.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147283684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vulvar dermatofibrosarcoma protuberans: Tubingen technique as an effective surgical approach for an atypical localization of a rare tumor.","authors":"Michele Lanzetti, Franca Taviti, Nicola Milanesi, Imma Savarese","doi":"10.23736/S2784-8671.26.08410-0","DOIUrl":"10.23736/S2784-8671.26.08410-0","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"299-301"},"PeriodicalIF":2.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147390106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutaneous metastasis of melanoma undergoing regression during targeted therapy: dermoscopic and histopathologic correlation.","authors":"Silvia Borriello, Umberto Santaniello, Francesco Cavallo, Paolo Fava, Matteo G Brizio, Giovanni Cavaliere, Rebecca Senetta, Simone Ribero, Pietro Quaglino","doi":"10.23736/S2784-8671.26.08408-2","DOIUrl":"10.23736/S2784-8671.26.08408-2","url":null,"abstract":"","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"298-299"},"PeriodicalIF":2.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146226721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}