Italian Journal of Dermatology and Venereology最新文献_第6页

Alopecia areata incognita in men masquerading as androgenetic alopecia: a case series of 29 patients in a single centre experience. 伪装成雄激素性脱发的男性的隐蔽性斑秃：在单一中心经验的29例患者的病例系列。

IF 2.6 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-08-01 Epub Date: 2025-06-23 DOI: 10.23736/S2784-8671.25.08170-8

Michela Starace, Bor Hrvatin Stancic, Stephano Cedirian, Federico Quadrelli, Francesca Pampaloni, Francesca Bruni, Aurora Alessandrini, Cosimo Misciali, Bianca M Piraccini

{"title":"Alopecia areata incognita in men masquerading as androgenetic alopecia: a case series of 29 patients in a single centre experience.","authors":"Michela Starace, Bor Hrvatin Stancic, Stephano Cedirian, Federico Quadrelli, Francesca Pampaloni, Francesca Bruni, Aurora Alessandrini, Cosimo Misciali, Bianca M Piraccini","doi":"10.23736/S2784-8671.25.08170-8","DOIUrl":"10.23736/S2784-8671.25.08170-8","url":null,"abstract":"Background: Alopecia areata incognita (AAI) represents a variant of alopecia areata with an absence of well-defined alopecic patches but diffuse involvement of the scalp and even if usually affected females, it may also appear in male. Little is known about AAI in men. The aim of this study was to characterize the history, clinical, trichoscopic, and histopathologic features of AAI in male patients.Methods: All histopathologically proven male patients with AAI between April 2011 and December 2023, were included in the study. The history, clinical, trichoscopic and histopathologic features of the male patients were evaluated.Results: Twenty-nine patients with AAI were included in the study, the mean age was 23.1. All patients had an underlying androgenetic alopecia (AGA) - Hamilton Scale: 17 (58.62%) grade IV, 9 (31.03%) grade V and 3 (10.34%) grade VI. The most common trichoscopic features included short regrowing hair (96.6%), yellow dots (89.7%) and pigtail hair (41.3%) especially seen in the occipital, parietal and frontal regions. A positive pull test with telogen roots was observed in 24.1% of the patients. Histopathological characteristics of AAI in male patients were indistinguishable from previously described features in female patients. All patients were treated with an ultra-potent topical corticosteroid under occlusion and topical 5% minoxidil twice/day or oral minoxidil, remission was established between 4-8 months after treatment initiation.Conclusions: A thorough trichoscopic examination in cases of diffuse hair loss in male patients with AGA refractory to conventional therapy is warranted and trichoscopy-guided biopsy is necessary to confirm the diagnosis.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":"309-313"},"PeriodicalIF":2.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144475159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical perspectives on prurigo nodularis: diagnostic challenges and novel treatment options. 结节性痒疹的临床前景：诊断挑战和新的治疗选择。

IF 2.6 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-08-01 DOI: 10.23736/S2784-8671.25.08289-1

Maria Concetta Fargnoli, Silvia Mariel Ferrucci, Giampiero Girolomoni, Anna Campanati, Caterina Foti, Cataldo Patruno, Piergiacomo Calzavara-Pinton, Andrea Chiricozzi, Simmi Wiggins, Claudia DE Cupis, Luca Stingeni

{"title":"Clinical perspectives on prurigo nodularis: diagnostic challenges and novel treatment options.","authors":"Maria Concetta Fargnoli, Silvia Mariel Ferrucci, Giampiero Girolomoni, Anna Campanati, Caterina Foti, Cataldo Patruno, Piergiacomo Calzavara-Pinton, Andrea Chiricozzi, Simmi Wiggins, Claudia DE Cupis, Luca Stingeni","doi":"10.23736/S2784-8671.25.08289-1","DOIUrl":"https://doi.org/10.23736/S2784-8671.25.08289-1","url":null,"abstract":"Prurigo nodularis (PN) is a chronic skin inflammatory condition characterized by severe, persistent itching and excoriated nodules induced by scratching. PN is strongly related to neural and immune dysfunction and negatively impacts quality of life. Treatments for PN are often off-label, highlighting the need for specifically approved agents and consensus guidelines for patient management. An Italian expert panel (including nine dermatologists) discussed four main clinical and therapeutic topics (definition and etiopathogenesis, diagnosis and staging, clinical management and therapy) based on their clinical experience and literature review. Data gaps were identified and a modified Metaplan® method was used to determine the consensus for each topic. PN, mainly affecting middle-aged and elderly adults, is a distinct disease from atopic dermatitis (AD), despite sharing some features (e.g. itch and inflammatory pathways). Although the pathophysiology of PN remains under debate, type 2 pro-inflammatory cytokines (e.g. interleukin IL-4, IL-13 and IL-31) are key mediators of both chronic pruritus and tissue changes. According to international definition, PN is a disease characterized by chronic (at least 6 months) pruritus and signs of repeated scratching, and well-defined nodules. Dupilumab (targeting the IL-4 receptor alpha inhibitor and inhibiting both IL-4 and IL-13) and nemolizumab (an IL-31 receptor alpha inhibitor) were recently approved for the treatment of PN, showing marked efficacy and favorable safety in randomised clinical trials. PN management requires a better understanding of disease pathophysiology, with comprehensive patient care strategies. Novel targeted therapies, such as dupilumab, are essential for improving patient outcomes in PN.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":"160 4","pages":"362-373"},"PeriodicalIF":2.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rituximab-induced nonuremic calciphylaxis in hairy cell leukemia: a singular case. 利妥昔单抗诱导的毛细胞白血病非尿毒症性钙化反应：一例。

IF 2.6 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-08-01 DOI: 10.23736/S2784-8671.25.08258-1

Eleonora Bongiovanni, Orsola Crespi, Cristina Sarda, Umberto Santaniello, Paolo Dapavo, Simone Ribero, Pietro Quaglino

引用次数: 0

Albendazole in the era of scabies resistance is better. 阿苯达唑在时代对疥疮的抵抗力较好。

IF 2.6 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-08-01 Epub Date: 2025-06-05 DOI: 10.23736/S2784-8671.25.08168-X

Alessio Natale, Stephano Cedirian, Michela Starace, Iria Neri, Valeria Evangelista, Corrado Zengarini, Bianca M Piraccini

引用次数: 0

Dermatitis herpetiformis, celiac disease and their impact on women and their families. 疱疹样皮炎、乳糜泻及其对妇女及其家庭的影响。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-07-22 DOI: 10.23736/S2784-8671.25.08178-2

Martin A Shahid, Elena B Mariotti, Kosara Drenovska, Snejina Vassileva, Cristina Aimo, Valentina Ruffo DI Calabria, Lavinia Quintarelli, Alessandro Magnatta, Simone Landini, Marta Donati, Alice Verdelli, Marzia Caproni

{"title":"Dermatitis herpetiformis, celiac disease and their impact on women and their families.","authors":"Martin A Shahid, Elena B Mariotti, Kosara Drenovska, Snejina Vassileva, Cristina Aimo, Valentina Ruffo DI Calabria, Lavinia Quintarelli, Alessandro Magnatta, Simone Landini, Marta Donati, Alice Verdelli, Marzia Caproni","doi":"10.23736/S2784-8671.25.08178-2","DOIUrl":"https://doi.org/10.23736/S2784-8671.25.08178-2","url":null,"abstract":"Dermatitis herpetiformis (DH) is the specific cutaneous manifestation of celiac disease (CD), both of which require lifelong management. A comprehensive literature review was conducted to gather evidence on gender-related differences aiming at reducing healthcare inequalities. While women tend to be more symptomatic, the diagnosis is often delayed, leading to a reduced quality of life and an increased risk of long-term complications. This may be partly a consequence of the fact that they are more likely to present with seronegative forms. Moreover, in women, reproductive issues, known to be associated with DH and CD, along with osteopenia/osteoporosis, and anemia are particularly prevalent. It should be also noted that beyond personal diagnosis, DH and CD also affect women indirectly, as they often take on caregiving roles for affected family members. The lifelong adherence to a gluten-free diet, the only effective treatment for DH, imposes a substantial lifestyle and financial burden. Gluten-free diet is frequently perceived as both gendered and class-based, placing a disproportionate strain on women and lower-income households. In this regard, recent recommendations to prioritize naturally gluten-free foods rather than \"gluten-free\" products, may offer some relief. However, the responsibility for acquiring the skills necessary for such dietary choices often falls predominantly on women.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144690223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnosis of scabies and socio-economic status in Ferrara, Italy: is there an association? 意大利费拉拉地区疥疮诊断与社会经济地位：是否存在关联？

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-07-22 DOI: 10.23736/S2784-8671.25.08181-2

Alessandro Borghi, Stefano Ferretti, Elisa Marzola, Sebastiano Posenato, Monica Corazza

{"title":"Diagnosis of scabies and socio-economic status in Ferrara, Italy: is there an association?","authors":"Alessandro Borghi, Stefano Ferretti, Elisa Marzola, Sebastiano Posenato, Monica Corazza","doi":"10.23736/S2784-8671.25.08181-2","DOIUrl":"https://doi.org/10.23736/S2784-8671.25.08181-2","url":null,"abstract":"Background: The role of socioeconomic status (SES) in the individual risk of contracting scabies in industrialized countries has not been specifically examined. This study aimed to assess potential associations between SES and scabies diagnosis.Methods: The SES of a retrospective cohort of subjects residing in the province of Ferrara, north-east Italy, who were diagnosed with scabies between 2016 and 2024, was evaluated. SES was represented through an ecological-based deprivation index that identified five subgroups, ranging from I (highest SES) to V (lowest SES).Results: A total of 307 subjects (188 males, ages ranging from 0 to 93 years) received a diagnosis of scabies at the local Dermatology Unit during the study period. The number of scabies diagnoses gradually increased. The distribution of patients across SES quintiles closely mirrored that of the general population in the same geographical area. However, scabies patients were more likely to belong to the two most deprived classes (IV and V) than to the highest SES classes (I and II) (P<0.001).Conclusions: Scabies is a widespread infestation that can affect anyone, regardless of their SES. Nevertheless, belonging to lower SES classes appears to increase the risk of contracting scabies: to a greater extent, scabies tends to affect individuals from more deprived backgrounds.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144690224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bad vibrations? The prevalence of itch and erythema induced by whole body vibration training: a questionnaire-based study in users and therapists. 坏的振动?全身振动训练引起的瘙痒和红斑的流行：一项基于用户和治疗师的问卷调查研究。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-06-01 DOI: 10.23736/S2784-8671.25.07942-3

Oliver Brandt, Jie Zhu, Manfred Hartard, Simon M Mueller

{"title":"Bad vibrations? The prevalence of itch and erythema induced by whole body vibration training: a questionnaire-based study in users and therapists.","authors":"Oliver Brandt, Jie Zhu, Manfred Hartard, Simon M Mueller","doi":"10.23736/S2784-8671.25.07942-3","DOIUrl":"10.23736/S2784-8671.25.07942-3","url":null,"abstract":"Background: The phenomenon of itch and erythema induced by whole body vibration (WBV) is extensively discussed in social media and popular press. The existence of this phenomenon has been confirmed in an experimental study by our group, however, its prevalence and dependency on technical settings (e.g. device, frequency, amplitude, intervals) has not been studied so far.Methods: This cross-sectional, questionnaire-based, multi-center study aimed to investigate itch and erythema in the use of WBV devices. Specially designed questionnaires were used to collect data on itch and/or erythema occurrence during WBV training, allergies, antiallergic drug intake, and technical aspects and settings of WBV.Results: A total of 67 WBV users and 15 therapists administering WBV participated. Of the 67 WBV-users, 22% experienced either itch or erythema. A majority of those with itch also had erythema, which often appeared during the first session and persisted in subsequent sessions. No permanent discontinuation of WBV-treatment due to symptoms was reported. While symptoms were more prevalent for side-to-side alternating vibration devices with a pooled prevalence of 31.4%, no symptoms were reported for the tri-planar device (P<0.001).Conclusions: In conclusion, itch and erythema may be underreported side effects experienced by WBV users, and appear to be related to the type of WBV device used.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":"160 3","pages":"212-218"},"PeriodicalIF":1.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Telemedicine and teledermatology between technological innovation and professional responsibility in Italy. 意大利远程医疗和远程皮肤科的技术创新与专业责任。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-06-01 DOI: 10.23736/S2784-8671.25.08046-6

Valerio Cirfera, Maurizio Congedo, Camila Scharf, Marco Polo, Cosimo Prete, Andrea Rosafio, Enrico M Procaccini

{"title":"Telemedicine and teledermatology between technological innovation and professional responsibility in Italy.","authors":"Valerio Cirfera, Maurizio Congedo, Camila Scharf, Marco Polo, Cosimo Prete, Andrea Rosafio, Enrico M Procaccini","doi":"10.23736/S2784-8671.25.08046-6","DOIUrl":"10.23736/S2784-8671.25.08046-6","url":null,"abstract":"Telemedicine utilizes communication technologies to provide healthcare services remotely, significantly impacting dermatology through the transmission and analysis of body surface images. Despite its benefits, telemedicine faces challenges including the quality of tools, operator competence, privacy issues, and responsibility allocation in cases of errors. The Italian Code of Medical Deontology emphasizes safety, proportionality, and the necessity of in-person examinations for initial consultations. Teleconsultations, online visits, and telemonitoring are essential forms of telemedicine that must adhere to ethical guidelines and protect patient privacy. Legal frameworks such as the Gelli-Bianco Law mandate professional responsibility and insurance coverage for telemedicine practices, equating them with traditional medical services. Legal challenges include data protection, informed consent, and the distribution of responsibility among healthcare providers and technology operators. Telemedicine, including teledermatology, offers substantial benefits but should not replace traditional in-person consultations, particularly in complex cases like dermato-oncology. Successful implementation requires a balanced approach, prioritizing patient well-being and professional responsibility. In conclusion, telemedicine provides an opportunity to enhance healthcare delivery, extending beyond physical and geographical limitations. However, it must complement traditional practices to optimize healthcare outcomes, adhering to all ethical and legal standards. Telemedicine's success hinges on a common-sense approach that emphasizes patient well-being, professional responsibility, and the integration of technological innovations into routine healthcare.","PeriodicalId":14526,"journal":{"name":"Italian Journal of Dermatology and Venereology","volume":"160 3","pages":"219-224"},"PeriodicalIF":1.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sequential combination treatment with doxycycline and isotretinoin in association with topical calcineurin inhibitors and metronidazole cream for the treatment of rosacea fulminans. 多西环素和异维甲酸序贯联合治疗局部钙调磷酸酶抑制剂和甲硝唑乳膏治疗暴发性酒渣鼻。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-06-01 DOI: 10.23736/S2784-8671.25.08096-X

Martina Cavicchi, Caterina Longo, Alberico Motolese, Alessia Paganelli

引用次数: 0

Hypopigmented mycosis fungoides in pediatrics. 儿科蕈样霉菌病的色素减退。

IF 1.8 4区医学

Italian Journal of Dermatology and Venereology Pub Date : 2025-06-01 Epub Date: 2025-02-25 DOI: 10.23736/S2784-8671.25.08169-1

Orsola Crespi, Isotta Giunipero DI Corteranzo, Eleonora Bongiovanni, François Rosset, Michela Ortoncelli, Federica Santoro, Simone Ribero, Pietro Quaglino

引用次数: 0