色素紫癜性皮肤病的临床管理:来自意大利皮肤病和性病学会皮肤血管疾病研究组调查的证据

IF 2.6 4区 医学 Q3 DERMATOLOGY
Alessia Paganelli, Andrea Michelerio, Maria C Collina, Maria A Pilla, Marco Spadafora, Caterina Longo, Annunziata Dattola, Antonio G Richetta, Giovanni Pellacani, Claudia Pezzini, Victor D Mandel, Francesca DI Tullio, Andrea Conti, Alfonso Motolese, Andrea Marani, Barbara DE Pace, Andrea Megna, Alessandra G Condorelli, Federica Arginelli, Flavia Persechino, Federico Garbarino, Luca Ambrosio, Emanuele Scala, Camilla Vassallo, Alberico Motolese
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引用次数: 0

摘要

背景:色素性紫癜性皮肤病(PPD)是一组慢性良性皮肤病,其诊断和治疗方面的循证数据有限。我们工作的目的是评估皮肤科医生在治疗PPD方面的临床实践,重点关注患者的表现、治疗偏好以及进一步诊断评估的必要性。方法:本研究采用基于调查的设计。该调查已分发给意大利皮肤病和性病学会皮肤血管疾病和皮肤溃疡研究小组。调查收集了关于每周接受评估的患者数量、要求治疗的患者比例、首选治疗方法和额外诊断测试适应症的数据。结果:来自11个中心的24名临床医生参与了研究。受访者报告平均每周处理5例PPD病例,大约50%的病例需要治疗,而其余病例是在评估其他皮肤病时偶然发现的。皮肤保湿剂和局部皮质类固醇(tCS)被普遍推荐作为一线治疗。其他治疗包括氧化锌乳膏、压缩长袜和以类黄酮为基础的口服补充剂。进一步的诊断检查,如腿部多普勒超声、皮肤活检和血液检查,被认为只有在基于临床表现和合并症的选定患者中才有必要。结论:保湿剂和tCS是PPD治疗的基石,辅以量身定制的治疗和诊断评估。这些发现强调需要标准化的循证指南来优化产后抑郁症的管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical management of pigmented purpuric dermatoses: evidence from a survey among the Study Group on Cutaneous Vascular Diseases of the Italian Society of Dermatology and Venereology.

Background: Pigmented purpuric dermatoses (PPD) are a group of chronic, benign skin conditions with limited evidence-based data regarding their diagnosis and management. The aim of our work was to evaluate the clinical practices of dermatologists in managing PPD, focusing on patient presentation, treatment preferences, and the need for further diagnostic evaluations.

Methods: We utilized a survey-based design for the present study. The survey was distributed to the Study Group on Cutaneous Vascular Diseases and Skin Ulcers of the Italian Society of Dermatology and Venereology. The survey collected data on the number of patients evaluated weekly, the proportion of patients requesting treatment, preferred therapeutic approaches, and indications for additional diagnostic tests.

Results: Twenty-four clinicians from 11 centers participated. Respondents reported managing an average of 5 PPD cases per week, with treatment required in approximately 50% of cases, while the remainder were incidental findings during evaluations for other dermatological conditions. Skin moisturizers and topical corticosteroids (tCS) were universally recommended as first-line treatments. Additional therapies included zinc oxide cream, compression stockings, and flavonoid-based oral supplements. Further diagnostic workups, such as leg Doppler ultrasound, skin biopsy, and blood tests, were considered necessary only in selected patients based on clinical presentation and comorbidities.

Conclusions: Moisturizers and tCS are the cornerstone of PPD treatment, supplemented by tailored therapies and diagnostic evaluations. These findings highlight the need for standardized, evidence-based guidelines to optimize the management of PPD.

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CiteScore
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