Irish Journal of Medical Science最新文献

{"title":"A study of tertiary hyperparathyroidism.","authors":"Bhoomika Venkateshappa, Prasanna Narayanaswamy, Koti Reddy Kandula Venkata, Gurupriya Madupuri, Varalakshmi Boreddy, Aiswarya Lakshmi Pavuluri, Rapur Ram, Siva Kumar Vishnubotla","doi":"10.1007/s11845-025-04034-y","DOIUrl":"https://doi.org/10.1007/s11845-025-04034-y","url":null,"abstract":"<p><strong>Introduction: </strong>Information on tertiary hyperparathyroidism (THPTH) among chronic kidney disease (CKD) patients on haemodialysis in developing countries such as India is limited, and the mortality among them remains a query.</p><p><strong>Materials and methods: </strong>This was a prospective cohort study conducted in at a tertiary care centre from June 2017 to June 2022. The index of suspicion for tertiary hyperparathyroidism was when investigations revealed high serum calcium and high alkaline phosphatase along with new onset of body aches, joint pains, and difficulty in walking. Patients, with above clinical features, were considered for 99 m Tc-Sestamibi scan and high-resolution ultrasound of the neck, when serum parathormone was > 600 pg/mL. Those patients diagnosed with tertiary hyperparathyroidism were followed up for 5 years.</p><p><strong>Results: </strong>The incidence of tertiary hyperparathyroidism among CKD patients was 13.4%. The mean age of CKD stage 5 patients with tertiary hyperparathyroidism was 55.17 ± 11.1 years. The observation from our study was the mean survival time among patients who underwent parathyroidectomy and among patients who received cinacalcet was almost similar, whereas the mean survival time among patients who received phosphate binders was lower. However, the survival rate among patients on cinacalcet and who underwent parathyroidectomy were not statistically significant.</p><p><strong>Discussion: </strong>There were no cross-sectional studies on prevalence of tertiary hyperparathyroidism in India as per our knowledge, although the prospective design, large sample size, PTH stratification, and frequent measurements of a comprehensive panel of mineral metabolites are strengths of the current study.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the impact of case mix factors on length of stay to a Complex Discharge Unit across three phases: pre-COVID-19 (2019), during COVID-19 (2021) and late-stage COVID-19 (2023) pandemic.","authors":"Tahira Bibi, Mbuotidem Udongwo, Joseph Deegan, Tom Cuddihy, Alanna Crawford, David Griffin, Keneilwe Malomo, Mohammed Tariq Zainal, Patrick Mc Cluskey, Haswadi Hassan, Declan Byrne, Joseph Browne, Ontefetse Ntlholang","doi":"10.1007/s11845-025-04072-6","DOIUrl":"10.1007/s11845-025-04072-6","url":null,"abstract":"<p><strong>Background/aims: </strong>Subacute complex discharge units (CDUs) offer intermediary person-centred care between acute hospital and community services by providing specialised care for patients with complex medical and functional needs. However, several elements of clinical practice were affected during the COVID-19 pandemic. We aimed to determine the impact of several case mix factors on length of stay and how this impact changed across three phases: pre-COVID-19 (2019), during COVID-19 (2021) and late-stage COVID-19 (2023) in our Complex Discharge Unit.</p><p><strong>Materials and methods: </strong>Before collecting data, our institution's Research and Innovation Office approved the study (reference number: 8900, on the 23rd of May 2024). All patients (920) who were admitted to our 23-bed Complex Discharge Unit in 2019 (320 patients), 2021(205 patients) and 2023 (395 patients) were evaluated. Data was inspected visually, and variables that predicted length of stay were included in a Poisson regression model to predict the length of stay.</p><p><strong>Results: </strong>An analysis of the relationship between year, age, medicolegal issues and length of stay, adjusting for several confounding variables (mobility status, healthcare-acquired infection, long-term care status, need for an increase in homecare package and need for a new homecare package) was carried out as there was an interaction. Charlson's Comorbidity (CCI) score and delirium were not predictive of length of stay. Medicolegal issues increased length of stay by a factor of 1.46 (95% CI 1.39-1.52, p < 0.001). For every 1-year increase in age, length of stay increased by a factor of 1.006 in 2019 (95% CI 1.004-1.01, p < 0.001), 0.988 in 2021 (95% CI 0.987-0.99, p < 0.001), and 1.004 in 2023 (95% CI 1.002-1.01, p < 0.001).</p><p><strong>Discussion and conclusion: </strong>Multimorbidity and delirium did not predict length of stay, while legal issues delayed discharges. On a unit with a baseline longer than average length of stay, there have been progressive improvements in length of stay over time, maybe hastened and retained from lessons learned from the pandemic.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144954503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AMSC/CXCR4-derived exosomes and miRNA-320 regulate pathological angiogenesis in diabetes.","authors":"Shenhao Wu, Xiaomei Luo, Yanwen Liu, Jing Gao","doi":"10.1007/s11845-025-04077-1","DOIUrl":"https://doi.org/10.1007/s11845-025-04077-1","url":null,"abstract":"<p><strong>Background: </strong>Diabetic vascular complications present significant clinical challenges, including limited treatment efficacy, high postoperative restenosis rates, and delayed early diagnosis. This study investigates CXCR4-modified adipose-derived mesenchymal stem cells (AMSCs/CXCR4) in regulating pathological endothelial proliferation under hyperglycemic conditions.</p><p><strong>Aims: </strong>The purpose is to provide new mechanism insights and potential therapeutic targets for early intervention of diabetes-related vascular diseases.</p><p><strong>Methods: </strong>The CXCR4-overexpressing plasmid was generated via XhoI/EcoRI double digestion, T4 ligation, and column purification, then transfected into AMSCs using Lipofectamine® 3000 to enhance exosome secretion. These exosomes were co-cultured with HG-treated HUVECs. Cell viability and apoptosis were assessed by CCK8 and flow cytometry. AKT/mTOR pathway proteins (total/phosphorylated) were analyzed via Western blot, while qRT-PCR quantified miRNA320, VEGF, and IGF-1 expression.</p><p><strong>Results: </strong>Chronic high glucose stimulated abnormal endothelial cell proliferation (CCK-8/flow cytometry), which was suppressed by AMSCs/CXCR4, reducing proliferation and elevating apoptosis ( 21.723 ± 1.061% apoptosis rate)). High glucose downregulated miRNA320, but AMSCs/CXCR4 restored its expression ( 0.937 ± 0.056 vs. other groups, P < 0.05). Increased miRNA320 correlated with reduced VEGF ((1.101 ± 0.142) and IGF-1 (1.074 ± 0.084) levels, confirming miRNA320-mediated inhibition. Notably, activation of the AKT/mTOR pathway proteins was not affected, indicating that AMSCs/CXCR4 directly inhibited the activity of VEGF and IGF-1 in HUVECs via miRNA320.</p><p><strong>Conclusions: </strong>CXCR4 boosts exosome release from AMSCs. Although AMSCs/CXCR4 did not alter AKT/mTOR signaling, their miRNA320-loaded exosomes blocked IGF-1/VEGF activity. This study uncovers a CXCR4-miRNA320 axis in diabetic vascular dysfunction, highlighting exosome-based therapy and miRNA320 as a targeted strategy for vascular complications.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144954568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent aphthous stomatitis information on TikTok: satisfactory or substandard?","authors":"Barry Patton, Anish Madan Lal, Richeal Ni Riordain","doi":"10.1007/s11845-025-04040-0","DOIUrl":"https://doi.org/10.1007/s11845-025-04040-0","url":null,"abstract":"<p><strong>Background: </strong>Social media is increasingly utilised as a means of disseminating oral health information. Recurrent aphthous stomatitis (RAS) is the most common ulcerating condition of the oral mucosa.</p><p><strong>Aim: </strong>The aim of this study was to evaluate the quality of TikTok videos concerning RAS.</p><p><strong>Material and methods: </strong>TikTok searches were performed using the terms \"canker sores/#cankersores\" and \"aphthous ulcers/#aphthousulcers\" and arranged by popularity. Videos were analysed and categorised into healthcare professionals (HCPs), non-healthcare professionals (non-HCPs) and other. Video quality was assessed using the Global Quality Score (GQS), modifed DISCERN (mDISCERN) and Patient Education Materials Assessment Tool (PEMAT).</p><p><strong>Results: </strong>Eighty-three videos were analysed. Overall, the videos were of poor quality with mean GQS and mDISCERN scores of 2.21 and 1.74 respectively. PEMAT understandability and actionability scores averaged 76.43% and 68.47% respectively. Videos uploaded by HCPs were generally of higher quality than others; this difference was statistically significant (p < 0.001). Weak positive correlation was noted between video engagement and quality (p < 0.05).</p><p><strong>Conclusion: </strong>The quality of videos examined was generally poor. It is important that social media users exert caution when utilising TikTok as a means of educating themselves about oral health. Additionally, healthcare professionals must be aware of health misinformation on social media, as it may negatively influence patient outcomes.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144954500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unusual presentation: concomitant segmental vitiligo, segmental morphea, and lichen striatus.","authors":"Zeynep Busra Balik, Gozde Simsek, Nur Defne Dogan, Pinar Celepli, Gulsen Akoglu","doi":"10.1007/s11845-025-04033-z","DOIUrl":"https://doi.org/10.1007/s11845-025-04033-z","url":null,"abstract":"<p><strong>Background: </strong>Segmental vitiligo, segmental morphea, and lichen striatus are distinct dermatological conditions that may share pathogenic mechanisms involving genetic mosaicism and immune dysregulation. Their simultaneous occurrence is extremely rare and may offer insights into their shared etiology.</p><p><strong>Case presentation: </strong>A 24-year-old female presented with a 6-year history of progressive indurated and discolored skin lesions. Dermatological examination revealed dermatomal depigmented macules consistent with segmental vitiligo on the right trunk, a violaceous Blaschkoid macule compatible with lichen striatus on the right lateral trunk, and multiple sclerotic plaques on the left side, consistent with segmental morphea. Histopathological examination confirmed the diagnosis of all three entities: loss of melanocytes in vitiligo, dermal sclerosis in morphea, and epidermal spongiosis with lymphocytic infiltrates and melanophages in lichen striatus.</p><p><strong>Conclusion: </strong>To our knowledge, this is the first reported case presenting the concurrent manifestation of segmental vitiligo, segmental morphea, and lichen striatus in the same patient. The segmental and Blaschkoid distribution patterns support a common pathogenic basis likely rooted in genetic mosaicism triggered by an autoimmune mechanism. Recognition of this rare co-occurrence may help elucidate the shared immunopathological mechanisms underlying these conditions.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144954508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abstracts for the 49th Sir Peter Freyer Surgical Symposium 2024 University of Galway 6th & 7th September 2024.","authors":"","doi":"10.1007/s11845-025-04062-8","DOIUrl":"10.1007/s11845-025-04062-8","url":null,"abstract":"","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":"194 Suppl 3","pages":"53-98"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144954492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Different types of oesophageal reconstructions in the contemporary era: a systematic review and network meta-analysis.","authors":"Muireann Keating, Matthew G Davey, William Murray, Eamon Franics, Noel E Donlon","doi":"10.1007/s11845-025-04073-5","DOIUrl":"https://doi.org/10.1007/s11845-025-04073-5","url":null,"abstract":"<p><strong>Introduction: </strong>Oesophageal reconstruction is a complex operation that continues to present a surgical challenge associated with significant morbidity and its associated sequelae. The conventional gastric conduit remains the gold standard reconstructive technique when available. Alternative conduits for oesophageal replacement become necessary when the stomach is unavailable with common options for conduit creation being the jejunum and the colon. The aim of this systematic review and network meta-analysis was to interrogate outcomes in oesophageal reconstruction with gastric pull-up, colonic interposition and jejunal flap.</p><p><strong>Methods: </strong>A systematic review of three electronic databases (PubMed, EMBASE and SCOPUS) was undertaken. An NMA as per the PRISMA-NMA guidelines. Statistical analysis was carried out using R and Shiny.</p><p><strong>Results: </strong>In a total of 19 studies, 3927 patients were included; 79.5% (3123/3927) of patients underwent gastric pull-up; 13.5% (531/3927) of patients underwent colonic interposition; 7% (273/3927) of patients underwent jejunal flap as their reconstructive method. At NMA, there was no significant difference in anastomotic leak rates, mortality rates, stricture formation, necrosis and length of stay between the three reconstructive techniques. Trend results showed jejunal flap performed better than colonic interposition in length of stay and mortality rates.</p><p><strong>Conclusion: </strong>At present, the gastric conduit is the conventional and first choice for oesophageal reconstruction ab initio after oesophagostomy. Colonic interposition and jejunal free flap represent viable options and are associated with non-inferior short-term surgical outcomes when gastric pull-up is not available or feasible.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144954547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nociception level index monitoring in intensive care: pain awareness in pressure ulcer care in unconscious patients: a randomized controlled pilot study.","authors":"Berna Caliskan, Zeki Beşir","doi":"10.1007/s11845-025-04078-0","DOIUrl":"https://doi.org/10.1007/s11845-025-04078-0","url":null,"abstract":"<p><strong>Background: </strong>Pain management in intensive care is challenging due to multiple potential causes. The physiological consequences of uncontrolled pain can adversely affect treatment. Reliable, objective pain monitoring may therefore improve care.</p><p><strong>Aims: </strong>To investigate the validity and clinical impact of the Nociception Level Index (NOL®) for guiding analgesia in intensive care patients.</p><p><strong>Methods: </strong>This randomized, prospective, controlled study included 40 ICU patients assigned to either a control group or a NOL-guided group (n = 20 each). During daily pressure ulcer care, the NOL group received analgesia according to continuous nociception monitoring, while the control group was managed with fentanyl boluses (1 µg/kg) guided by the Critical Care Pain Observation Tool (CPOT). Hemodynamic variables and variability were also assessed.</p><p><strong>Results: </strong>Total fentanyl use was significantly higher in the NOL group (67.5 ± 53.25 µg) than in the control group (37.5 ± 32.9 µg), with a mean difference of 30 µg (95% CI 1.7-58.3 µg, p = 0.04, Cohen's d = 0.68), corresponding to ~ 40% greater opioid use. At the start of care, systolic blood pressure (SBP) was higher in the control group (mean difference 12.5 mmHg, 95% CI 2.1-22.9 mmHg, p = 0.02, d = 0.62), while delta SBP was lower in the NOL group (mean difference -8 mmHg, 95% CI -15.2 to -0.8 mmHg, p = 0.03, d = 0.58).</p><p><strong>Conclusion: </strong>NOL® monitoring may serve as an effective tool to guide analgesic needs in unconscious ICU patients, enabling objective pain assessment and contributing to hemodynamic stability.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144954550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The expression trend and regulatory role of miR-484 in patients with gestational diabetes mellitus.","authors":"Yan Hou, Li Wan, Lijia Long","doi":"10.1007/s11845-025-04043-x","DOIUrl":"https://doi.org/10.1007/s11845-025-04043-x","url":null,"abstract":"<p><strong>Objective: </strong>Gestational diabetes mellitus (GDM) is characterized by the onset of abnormal glucose metabolism during pregnancy. This study aims to examine the expression patterns and functional significance of miR-484 in GDM.</p><p><strong>Methods: </strong>The levels of miR-484 in GDM patients were compared to those in normal pregnant women through RT-qPCR. Subsequently, the diagnostic and predictive capacity of miR-484 for GDM was assessed utilizing Receiver Operating Characteristic (ROC) curve. In the next phase, the effects of miR-484 on blood glucose levels and insulin resistance in GDM mice were studied by establishing a GDM mouse model. Finally, pancreatic tissues were isolated to elucidate the influence of miR-484 on inflammation processes and oxidative stress.</p><p><strong>Results: </strong>Elevated levels of miR-484 have been observed in GDM patients, demonstrating a positive correlation with blood glucose levels. ROC curve analysis indicated that miR-484 possesses substantial diagnostic and predictive capabilities for GDM, with an AUC of 0.835, a sensitivity of 80.95%, and a specificity of 82.00%. Furthermore, in GDM models, the downregulation of miR-484 significantly mitigated the adverse effects associated with GDM, leading to notable reductions in blood glucose levels and insulin resistance. Following the down-regulation of miR-484, a notable reduction in the levels of IL-1β, TNF-α, IL-6, and MDA in the pancreas was also observed. Concurrently, there was a significant increase in the levels of SOD and CAT.</p><p><strong>Conclusion: </strong>miR-484 might act as a biomarker for the early-stage recognition of GDM. Down-regulating this molecule is beneficial for lowering blood glucose, insulin resistance, and pancreatic inflammation or oxidative stress.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144954482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilization of a novel radio-opaque 3D printed phantom for simulation training of CT-guided interventional procedure.","authors":"Peter McAnena, Kevin J O'Sullivan, Aidan O'Sullivan, Karan Gupta, Alice Shannon, Leonard W O'Sullivan, Jennifer Ni Mhuircheartaigh","doi":"10.1007/s11845-025-04070-8","DOIUrl":"https://doi.org/10.1007/s11845-025-04070-8","url":null,"abstract":"<p><strong>Background: </strong>Training radiology residents to perform CT-guided procedures can be challenging due to limited access to scanner time, competition for procedures with other residents and fellows and the risk of exposing patients to unnecessary additional radiation due to the inexperience of the primary operator. Simulation training has shown great benefit in reducing patient risk and increasing training opportunities. The aim of this study was to assess the impact of a high-fidelity 3D-printed model as an interventional radiology training tool for trainees.</p><p><strong>Methods: </strong>This study was approved by the local research ethics committee. Using anonymised patient scan data from a prone CT colonography study, the pelvis and two vertebrae were 3D printed in an experimental radiopaque resin. A five-sided mould was created for casting the pelvic phantom. The lower back soft tissue impression was converted to a surface using Geomagic software. This surface was subtracted from a solid base using a Boolean extraction. Gel wax was gently poured into the mould to reduce air bubble formation. The phantom was allowed to cool and solidify overnight. Radiology trainees at our institution were invited to participate in the study and received formal teaching by a musculoskeletal fellowship-trained radiologist before performing two independent CT-guided needle placements on the model. Data were recorded on trainee confidence prior to and after the training session, time to complete the procedure and dose to the model for each attempt and compared using paired t-tests.</p><p><strong>Results: </strong>Twelve radiology trainees took part in the study. Mean total procedure time and dose to the model decreased significantly for the second attempt compared to their first attempt at needle placement in the SI joint (6.9 vs. 4.2 min, p = 0.008, DLP 31.1 vs. 25.9, p = 0.022 respectively). Trainees were significantly more confident in performing a CT-guided SI joint injection following the training session.</p><p><strong>Conclusion: </strong>This study demonstrates that a 3D-printed model hip can provide a valuable training experience for radiology trainees for performing CT-guided interventions and can improve performance and confidence, without conferring any risk to patients. This model could be incorporated into radiology training curricula.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144954517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}