Irish Journal of Medical Science最新文献

{"title":"Impact of changes in gestational diabetes mellitus diagnostic criteria during the COVID-19 pandemic.","authors":"Jessica Neville, Kelly Foley, Seán Lacey, Antoinette Tuthill, Oratile Kgosidialwa, Mairead O'Riordan, Fiona O'Halloran, Seán J Costelloe","doi":"10.1007/s11845-025-03926-3","DOIUrl":"10.1007/s11845-025-03926-3","url":null,"abstract":"<p><strong>Background/aims: </strong>During the COVID-19 pandemic, the Health Service Executive (HSE) and Royal College of Obstetricians and Gynaecologists (RCOG) recommended fasting and random plasma glucose (FPG/RPG) alongside glycated haemoglobin (HbA_1c) to replace the oral glucose tolerance test (OGTT) for diagnosing Gestational Diabetes Mellitus (GDM).</p><p><strong>Methods: </strong>The study compared testing patterns and diagnostic rates for GDM before and after implementing the RCOG guidelines (01/05/2020) in pregnancies beginning 01/11/2018 to 31/03/2021. Trends were inspected using Cochrane-Armitage tests. Differences between General Practice (GP) and Secondary Care (SCare) were assessed by chi-square analysis. A significance level of p < 0.05 was used for all analyses. Information on maternal and pregnancy characteristics was accessed where available.</p><p><strong>Results: </strong>Data indicated a significant reduction in OGTTs requested by GPs and SCare. Conversely, HbA_1c, FPG and RPG test requests increased significantly in both locations. The overall GDM positivity rate increased significantly from 7.4% to 22.0% in GP and 16.9% to 39.0% in SCare following RCOG guideline implementation.</p><p><strong>Conclusions: </strong>The RCOG guidelines appear to have been well adopted by GPs and SCare, with greater adherence in SCare. Using FPG, RPG and HbA_1c to a greater extent than the OGTT corresponded with increased GDM diagnostic rates. Given the difficulties with interpreting HbA_1c in pregnancy, its routine use in diagnosing GDM requires further careful consideration. Relaying changes in diagnostic protocol during pandemics requires strong communication with all requesting clinicians, including GPs. Comparisons between GP and SCare indicated significant differences in test-requesting practices and GDM positivity rates.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"1097-1104"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12276109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143615595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving the quality of transurethral resection of bladder tumour (TURBT) operative notes following the European Association of Urology guidelines.","authors":"Paul C Ryan, Diarmuid D Sugrue, Clare O'Connell, Ahmed Salloum, Thomas H Lynch, Lisa Smyth, Imtiaz Ahmed, John Sullivan, Rustom P Manecksha, Peter E Lonergan, Louise C McLoughlin","doi":"10.1007/s11845-025-03940-5","DOIUrl":"10.1007/s11845-025-03940-5","url":null,"abstract":"<p><strong>Background: </strong>Transurethral resection of bladder tumour (TURBT) is the gold standard for diagnosing and risk-stratifying bladder cancer. Accurate and comprehensive operative documentation is critical for ensuring effective patient management. The European Association of Urology (EAU) guidelines provide a framework for TURBT documentation, including tumour characteristics, procedural details, and complications. However, adherence to these guidelines varies, necessitating quality improvement initiatives.</p><p><strong>Aims: </strong>This study aimed to assess the quality of TURBT operative notes at a single institution before and after implementing a standardised electronic TURBT template based on EAU guidelines.</p><p><strong>Methods: </strong>A closed-loop audit was conducted at an academic teaching hospital. Operative notes for 40 consecutive TURBT cases from December 2021 to September 2022 were evaluated against EAU documentation criteria. Following the introduction of a standardised electronic TURBT template, a second audit cycle of 40 cases from September 2022 to March 2023 was conducted. Key documentation elements, including tumour location, appearance, size, multifocality, procedural steps, resection completeness, and complications, were compared.</p><p><strong>Results: </strong>The introduction of the electronic template significantly improved documentation adherence, increasing overall compliance from 69 to 93%. Notable improvements were observed in tumour appearance (65 to 97.5%), tumour size (67.5 to 90%), completeness of resection (55 to 95%), and complication recording (2.5 to 75%).</p><p><strong>Conclusions: </strong>A structured electronic TURBT template enhances the quality and completeness of operative documentation, aligning with EAU guidelines. Standardised templates facilitate better communication, continuity of care, and quality improvement in TURBT procedures, ultimately contributing to improved patient management and outcomes.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"847-851"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12276090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency of post-traumatic stress disorder among orthopedic trauma patients and its association with personal parameters.","authors":"Fareeha Qamar, Amna Mehboob, Amna Rehman, Ali Afzal, Muhammad Babar Khawar","doi":"10.1007/s11845-025-03914-7","DOIUrl":"10.1007/s11845-025-03914-7","url":null,"abstract":"<p><strong>Background and objectives: </strong>Post-traumatic stress disorder (PTSD) is a common psychological condition following traumatic events, including physical trauma. In this study, we aimed to determine the prevalence and demographic correlates of PTSD among orthopedic trauma patients.</p><p><strong>Methods: </strong>We used a cross-sectional survey design and assessed 200 orthopedic trauma patients, using a self-administered questionnaire. The questionnaire consisted of demographic information and the PTSD Checklist-Civilian Version to determine the prevalence of PTSD.</p><p><strong>Results: </strong>The results showed that the prevalence of PTSD was 39%. Females had a higher incidence rate (63%) than males (26%). Females were 1.16 times more likely to suffer from PTSD following trauma as compared to males, with a statistically significant association found between PTSD and female gender. However, the study found no significant association between PTSD and age. Additionally, a high proportion of PTSD participants had comorbid depression.</p><p><strong>Conclusion: </strong>Future studies should further explore the demographic and psychological risk factors associated with PTSD following physical trauma.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"1031-1037"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emergency anaesthesia drug preparation in Irish training hospitals; a national survey.","authors":"Seán Boyd, Jack Collins","doi":"10.1007/s11845-025-03962-z","DOIUrl":"10.1007/s11845-025-03962-z","url":null,"abstract":"<p><strong>Introduction: </strong>Anaesthetic and intensive care (ICU) non-consultant hospital doctors (NCHDs) cover critical care areas along with theatre anaesthesia and maternity care during on call hours. NCHDs often prepare emergency drugs so that they are available for immediate use. The nature of this is not standardised nationally and may be department driven or at the discretion of the NCHD.</p><p><strong>Aims: </strong>The aim of this survey was to ascertain the practice in Irish acute hospitals in relation to drug preparation, transport, storage, specific protocols, and the availability of prefilled syringes.</p><p><strong>Methods: </strong>A telephone survey of each department was undertaken between 15th February to 2nd July 2024. With consent, 17 anaesthetic NCHDs were contacted to complete a phone survey.</p><p><strong>Results: </strong>The rate of use of each drug was ascertained for each tier of call. The storage and transport methods were recorded. The availability of prefilled syringes at each site was ascertained. Differences were reported between model 3 and model 4 hospitals.</p><p><strong>Conclusion: </strong>Guidance on essential anaesthetic drugs exists. However, we are not aware of any specific guidelines relating to drug preparation for on call service. Each hospital may provide different services and treat a different cohort of patients. Therefore, the need for standardised protocols would need to be assessed on a hospital-specific basis.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"1127-1129"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A scoping review of historical and contemporary management strategies for paediatric scrotal trauma.","authors":"Kenneth Patterson, Derek B Hennessey, Fardod O'Kelly","doi":"10.1007/s11845-025-03929-0","DOIUrl":"10.1007/s11845-025-03929-0","url":null,"abstract":"<p><strong>Objective: </strong>To perform a scoping review of the literature pertaining to paediatric scrotal trauma and to contrast operative with conservative management in this cohort of patients using available data.</p><p><strong>Methods: </strong>A search of Cochrane, SCOPUS, and EMBASE databases was performed using methods pre-published on PROSPERO. Reporting followed Preferred Reporting Items for Systematic Review and Meta-analysis guidelines. Eligible studies were articles or abstracts published in English describing the management of paediatric scrotal trauma, which reported at least one secondary outcome. The intended primary analysis is to report the management of paediatric scrotal trauma and the outcome based on management.</p><p><strong>Results: </strong>Thirty-six studies were identified, totaling 253 patients. Then, 91.7% of cases presented with unilateral testicular injury and 94.5% of cases resulted from blunt trauma. Then, 86% of patients presenting with scrotal trauma underwent ultrasound imaging of the scrotum. One hundred twenty-three cases underwent conservative management, 116 cases underwent acute surgical management, and 14 underwent delayed surgical management, with a mean time to an intervention of 3 days. Thirty patients were found to have testicular atrophy, with a mean follow-up of 14 months, of these 30 patients, 63% (n = 19) were conservatively managed, 20% (n = 6) were managed with acute surgical repair, and 17% (n = 5) were managed with delayed surgical repair.</p><p><strong>Conclusion: </strong>Paediatric testicular trauma is a rare presentation. A high level of suspicion is mandatory when testicular rupture is suspected. Early exploration is warranted in the setting of high risk and provides an excellent chance of testicular salvage.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"995-1001"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12276120/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and efficacy of prusogliptin in type-2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials.","authors":"Abdul Moeed, Muhammad Ahmed Ali Fahim, Afia Salman, Tooba Saqib, Laiba Zafar, Hoorain Jamil, Alishba Adnan Janjua, Syed Muhammad Muneeb Akhtar, Hamna Ahmed Khan, Hajra Zainab Chaudry, Ayesha Ali, Laiba Sanober, Muqaddas Parvez, Hala Najeeb, Abdul Hannan Siddiqui, Salim Surani","doi":"10.1007/s11845-025-03948-x","DOIUrl":"10.1007/s11845-025-03948-x","url":null,"abstract":"<p><strong>Background: </strong>This study aims to conduct a systematic review and meta-analysis of the currently present literature analyzing the effectiveness and safety profile of prusogliptin, a novel dipeptidyl peptidase-IV (DPP-4) inhibitor, as compared to placebo in type 2 diabetes mellitus (T2DM) patients.</p><p><strong>Methods: </strong>This systemic review and meta-analysis complied with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The search strategy based on various MeSH terms was run on: PubMed/Medline, SCOPUS, and Cochrane Central, which were then systematically searched from inception till March 2024 to select all relevant Randomized Control Trials (RCT).</p><p><strong>Results: </strong>The analysis of the findings from three RCTs with 957 patients revealed that prusogliptin reduced Hemoglobin A1c (HbA1c)% levels in T2DM patients significantly [Mean Difference (MD): -0.62, 95% Confidence Interval (CI): -0.74 to -0.50, I² = 0%, p < 0.001] and led to more patients with a HbA1c% ≤ 7% [Odds Ratio (OR): 2.65, 95%CI: 1.94 to 3.61, I² = 0%, p < 0.00001]. However, prusogliptin led to a non-significant increase in weight when compared with placebo (MD: 0.22, 95% CI: -0.50 to 0.93, I² = 60%, p = 0.551). The safety profile of prusogliptin revealed a non-significant decrease in treatment-emergent adverse events (OR: 0.90, 95% CI: 0.59 to 1.38, I² = 43%, p = 0.64) and a non-significant increase in treatment-emergent serious adverse events (OR: 1.02, 95% CI: 0.43 to 2.44, I² = 0%, p = 0.96) and drug-related adverse events (OR: 1.07, 95%CI: 0.68 to 1.69, I² = 0%, p = 0.76).</p><p><strong>Conclusion: </strong>Prusogliptin has a favorable efficacy in attaining glycemic control in patients with T2DM. However, its safety profile yields uncertain outcomes. More literature is required for a definitive result.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"887-898"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preventing chronic low back pain: investigating the role of Pilates in subacute management-a randomized controlled trial.","authors":"Hatice Kubra Asik, Tugba Sahbaz","doi":"10.1007/s11845-025-03939-y","DOIUrl":"10.1007/s11845-025-03939-y","url":null,"abstract":"<p><strong>Background: </strong>Subacute low back pain (LBP) is a critical phase that can determine long-term patient outcomes. Exercise therapy, including Pilates, is widely used to manage LBP, but its effectiveness in the subacute phase remains underexplored. This randomized controlled trial aims to compare the effects of an 8-week Pilates-based intervention versus a home exercise program on pain intensity, functional disability, and quality of life in patients with subacute LBP.</p><p><strong>Methods: </strong>Sixty-six participants with subacute LBP were randomized into two groups: a supervised Pilates group and a home exercise group. Pain intensity (Visual Analog Scale), functional disability (Roland-Morris Disability Questionnaire), and quality of life (Short Form-36) were assessed at baseline, post-intervention, and 3-month follow-up.</p><p><strong>Results: </strong>Both groups exhibited significant improvements in all outcome measures (p < 0.001). However, the Pilates group showed superior reductions in pain intensity (p = 0.010 post-treatment, p = 0.002 at follow-up) and functional disability (p = 0.009 and p = 0.002). Additionally, quality of life scores improved more significantly in the Pilates group, particularly in physical function (p = 0.031 and p = 0.025) and general health (p = 0.005 and p = 0.012).</p><p><strong>Conclusions: </strong>Pilates-based rehabilitation was more effective than a home exercise program in improving pain, disability, and quality of life in patients with subacute LBP. These findings support the inclusion of Pilates in early-stage rehabilitation to prevent chronicity.</p><p><strong>Trial registration: </strong>Clinical Trials Number: NCT06699511.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"949-956"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12276093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143779975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of abdominal aortic calcification score in predicting cardiovascular risk in the general population.","authors":"Yinze Ji, Naqiang Lv, Yingzhen Gu, Xiaorong Han, Aimin Dang","doi":"10.1007/s11845-025-03877-9","DOIUrl":"10.1007/s11845-025-03877-9","url":null,"abstract":"<p><strong>Background: </strong>Abdominal aortic calcification (AAC) is closely related to cardiovascular disease. Although its clinical significances have primarily been investigated in patients with chronic kidney disease, its association with cardio-cerebrovascular mortality in the general middle-aged and elderly population has not been sufficiently investigated.</p><p><strong>Aims: </strong>To study the association of AAC and cardio-cerebrovascular mortality in both the entire general middle-aged and elderly populations and age subgroups.</p><p><strong>Methods: </strong>Data of participants of the National Health and Nutrition Examination Survey (NHANES) 2013-2014 were analyzed. This study included middle-aged and elderly (≥ 40 years old) individuals who underwent dual-energy X-ray absorptiometry. The severity of AAC was assessed by an AAC scoring system (AAC score) with a maximum possible value of 24. Participants were tracked for survival status and major cause of death till 31st December 2019. This study utilized AAC score = 6 as the optimal cut-off according to Harrell's c statistic. Based on AAC scores, participants were trichotomized (0, 0-6, and ≥ 6). Groupwise survival curves and cumulative incidence functions were plotted to reveal the association of AAC and cardio-cerebrovascular mortality. Given results under trichotomization, combination of participants with AAC scores 0 and 0-6 was conducted to reaffirm the association of AAC and adverse prognosis.</p><p><strong>Results: </strong>Correlation between increased AAC score and poorer survival, higher cumulative incidence of events was revealed. Cox models identified AAC score ≥ 6 as an independent risk factor of cardio-cerebrovascular mortality (AAC score ≥ 6 vs. AAC score = 0: Hazard ratio: 2.38, P = 0.008) after adjusting for cardiovascular risk factors. Results remained significant after regrouping (AAC score ≥ 6 vs. AAC score < 6: Hazard ratio: 2.06, P = 0.016). Subgroup analysis provided no evidence of unparallel change in hazard for the same amount of increase in AAC score among middle-aged (40-65 years old) and elderly (≥ 65 years old) individuals.</p><p><strong>Conclusions: </strong>AAC score ≥ 6 independently indicate increased risk of cardio-cerebrovascular death and would be effective in risk stratification among the general middle-aged and elderly population in clinical practice.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"853-866"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Age‑related volume decrease in subcortical gray matter is a part of healthy brain aging in men.","authors":"Radmila Peric, Igor Romčević, Milica Mastilović, Ivana Starčević, Jasmina Boban","doi":"10.1007/s11845-025-03925-4","DOIUrl":"10.1007/s11845-025-03925-4","url":null,"abstract":"","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"1185"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbiologic features of prosthetic joint infections at a tertiary referral orthopaedic unit.","authors":"Stephen Christopher Murphy, Shane P Russell, James A Harty, Padhraig O'Loughlin","doi":"10.1007/s11845-025-03933-4","DOIUrl":"10.1007/s11845-025-03933-4","url":null,"abstract":"<p><strong>Background: </strong>Prosthetic joint infections (PJI) are a potential devasting consequence of arthroplasty surgery. Knowledge of the causative organism and antimicrobial sensitivity increases eradication success rates for PJI.</p><p><strong>Aims: </strong>This study aimed to: 1) Observe the PJI microbiome at a tertiary referral arthroplasty unit; 2) Make comparison to similar published observations; and; 3) Establish empiric local antibiotic PJI guidelines.</p><p><strong>Methods: </strong>All patients with positive tissue cultures for PJIs over a 4 year period were included. An electronic microbiology laboratory database search was performed to identify isolated microorganisms, sensitivities and resistances. Time from index procedure to PJI onset was recorded. The identified PJI microbiome was compared to current literature.</p><p><strong>Results: </strong>86 patients involving 88 joints were included. 56% (n = 49) related to hip, 42% (n = 37) to knee and 2% (2) to shoulder arthroplasty procedures. Coagulase Negative Staphylococci (CoNS) were isolated in 32% of cases, Staphylococcus aureus (SA) in 23%, Enterococcus species and Streptococcus species in 9.0%. 19% of case occurred within 3 months of index surgery, 17% from 3-12 months and 64% after 12 months. The microbiome identified varied comparable studies.</p><p><strong>Conclusion: </strong>This study describes a local PJI microbiome with contrasting results from comparable studies. Empiric antibiotic guidelines have been established to target treatment and a local PJI register has since been established to improve patient outcomes and antimicrobial stewardship in an era of antibiotic resistance.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"1011-1015"},"PeriodicalIF":1.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12276118/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}