{"title":"The frequency of unexpected tumors in appendectomy specimens from patients with acute appendicitis.","authors":"Xiaodong Hu, Liqi Li","doi":"10.1007/s11845-024-03832-0","DOIUrl":"10.1007/s11845-024-03832-0","url":null,"abstract":"","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142557842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The 46th Annual Meeting of the Irish Endocrine Society Meeting Programme and Abstracts 2022.","authors":"","doi":"10.1007/s11845-024-03824-0","DOIUrl":"https://doi.org/10.1007/s11845-024-03824-0","url":null,"abstract":"","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Selected abstracts from the 47th meeting of the Irish Endocrine Society Sligo, 24th & 25th November 2023.","authors":"","doi":"10.1007/s11845-024-03823-1","DOIUrl":"https://doi.org/10.1007/s11845-024-03823-1","url":null,"abstract":"","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The value of lncRNAs as a biomarker for the pregnancy outcomes of gestational diabetes: a meta-analysis.","authors":"Chunling Bao, Jun Kuang, Chuanyong He, Hui Xu","doi":"10.1007/s11845-024-03828-w","DOIUrl":"https://doi.org/10.1007/s11845-024-03828-w","url":null,"abstract":"<p><strong>Background: </strong>Long non-coding RNAs (lncRNAs) are tissue-specific and highly stable and may serve as early molecular markers of adverse pregnancy outcomes in patients with gestational diabetes mellitus (GDM).</p><p><strong>Aims: </strong>This study aimed to investigate the relationship between aberrant expression of lncRNAs and adverse pregnancy outcomes in GDM patients.</p><p><strong>Methods: </strong>We searched electronic databases: Embase, Medline, EBSCO, PubMed, CNKI, and Wanfang databases to find relevant articles. Included studies quality was assessed using the QUADAS-2 quality assessment tool. Prognostic value of lncRNAs were pooled using risk ratio (RR) with 95% confidence interval (95%CI). The heterogeneity was analyzed using the Cochran Q test and I<sup>2</sup> statistical test, and subgroup analyses were performed to explore the sources of heterogeneity. Begg's test funnel plots were analyzed for publication bias.</p><p><strong>Results: </strong>The review included nine studies. Overall, the review found that altered expression of lncRNAs was associated with adverse pregnancy outcomes of GDM patients (RR: 1.616, 95%CI: 1.308-1.996), and was a risk factor for adverse pregnancy outcomes both of Infants (RR: 1.68, 95% CI: 1.30-2.17) and maternal (RR: 4.14, 95% CI: 1.90-9.03) in patients with GDM. The diagnostic procedure, diagnostic criteria, expression trend of lncRNAs, and adverse pregnancy outcomes were the sources of heterogeneity.</p><p><strong>Conclusions: </strong>Aberrant expression of lncRNAs was strongly associated with the adverse pregnancy outcomes in GDM.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prostate Specific Antigen (PSA) testing in a general practice 2009-2019.","authors":"Niall Maguire, Andrea Moloney, Krzysztof Fic","doi":"10.1007/s11845-024-03804-4","DOIUrl":"https://doi.org/10.1007/s11845-024-03804-4","url":null,"abstract":"<p><strong>Background: </strong>Prostate-specific antigen (PSA) testing is not recommended as a population screening measure for prostate cancer. PSA testing is nevertheless widespread and is associated with harm due to false-positive test results, overdiagnosis and economic costs.</p><p><strong>Aims: </strong>This study sought to document the exposure of patients to PSA testing over a decade in a general medical practice setting.</p><p><strong>Methods: </strong>Laboratory results for each year were extracted from the clinical record. A chart review was undertaken for cases of prostate cancer.</p><p><strong>Results: </strong>We report 13,743 PSA results in 3313 men. In any year, 18% of all men and 33% of men aged over 50 years had at least one PSA test. Between 4.8 and 21% of first tests exceeded age normal values depending on age. There were 113 incident cancers in the study interval of which 84 (74%) were screen detected. Mortality was lower in screen-detected than symptomatic cancers.</p><p><strong>Conclusions: </strong>Men at our practice are significantly exposed to PSA testing. We found evidence of possible overdiagnosis.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142500570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aoife Brick, Brendan Walsh, Leonie Hill, Caragh Behan, Antoinette Daly, Sarah Craig
{"title":"Determinants of acute psychiatric inpatient length of stay in Ireland.","authors":"Aoife Brick, Brendan Walsh, Leonie Hill, Caragh Behan, Antoinette Daly, Sarah Craig","doi":"10.1007/s11845-024-03819-x","DOIUrl":"https://doi.org/10.1007/s11845-024-03819-x","url":null,"abstract":"<p><strong>Background: </strong>Ireland has had an historic over-reliance on inpatient mental health care accompanied by poorly resourced community provision. There has been an increasing policy focus on provision of mental health care in the community to facilitate diversion from, or shorten stays in, inpatient care. However, little is known about the determinants of psychiatric inpatient length of stay (LOS) to allow for the targeting of community services.</p><p><strong>Aim: </strong>To use a large cross-sectional national dataset to examine the determinants of psychiatric inpatient LOS in the Irish context.</p><p><strong>Methods: </strong>Using information on 60,607 discharges from adult acute psychiatric units in Ireland between 2015 and 2019, the study employs both descriptive and regression analysis. Using negative binomial regression models, we control for patient demographic, socioeconomic, and clinical characteristics. In addition, as LOS may be related to provision of non-acute services in the patient area of residence, the analysis also controls for aspects of community service provision.</p><p><strong>Results: </strong>The study finds that longer LOS is associated with older age, being female, and having an involuntary admission. Clinical diagnosis significantly impacts LOS, with diagnoses such as schizophrenia being associated with longer LOS. There is also significant variation in LOS across region of residence, with discharges from some regions staying up to 5 days longer.</p><p><strong>Conclusions: </strong>The regional variation observed in inpatient LOS supports the assumption that increased provision of community services diverts or reduces the quantum of care required in inpatient settings. However, without substantive improvement in the community data collected and reported, future planning of mental health services, both community and inpatient, will be substantially curtailed.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed Bagir Al-Sharaa, Mustafa M Al-Edanni, Mohammed Sh Al-Edanni, Ali Ehsan Alwindawi
{"title":"Comparison between early and late weight bearing after anterior cruciate ligament reconstruction surgery.","authors":"Mohammed Bagir Al-Sharaa, Mustafa M Al-Edanni, Mohammed Sh Al-Edanni, Ali Ehsan Alwindawi","doi":"10.1007/s11845-024-03796-1","DOIUrl":"https://doi.org/10.1007/s11845-024-03796-1","url":null,"abstract":"<p><strong>Background: </strong>The anterior cruciate ligament (ACL) is a strip of dense connective tissue that runs from the femur to the tibia with a relatively poor blood supply. It prevents the femoral condyles from rolling posteriorly. ACL is commonly injured in any knee trauma, ranging from a little sprain to a total rupture. The arthroscope is the gold standard approach for identifying ACL tears, which may be treated conservatively or surgically.</p><p><strong>Aim of the study: </strong>To assess the efficiency of immediate and delayed weight bearing after arthroscopic ACL reconstruction.</p><p><strong>Material and methods: </strong>Cohort longitudinal study carried through 6 years from 2017 to 2023 et al.-kindy Teaching, Ulamaa, and Almuktar hospitals 186 patients, the patients were divided randomly into 2 groups, group A (n = 93) with immediate (after 10 days) weight bearing and group B (n = 93) with delayed (after 1 month) weight bearing following ACL reconstruction. any patients with chondral lesions, aged less than 19 or more than 40 years, knee osteoarthritis, ligament damage, and deformity in lower extremities were excluded. Patients from both groups A and B had complete ACL tears and underwent arthroscopic ACL reconstruction follow-up for 6 months duration regarding stiffness, infection, giving up pain, swelling, and quadriceps muscle atrophy.</p><p><strong>Results: </strong>In group A, there were 93 patients,70 male and 23 female, and meniscal injury was 89 patients. While in group B (93 patients) 57 male and 36 female, meniscal injury in group B was 91. There is a statistically significant difference regarding knee swelling. (80.6% in group A, and 10.8% in group B), and knee pain in which (79.6% in group A patients and only 7.5% in group B). There is no significant value between the two groups about the knee getting given up, infection, stiffness, and quadriceps muscle atrophy.</p><p><strong>Conclusion: </strong>Delay weight bearing after ACL reconstruction makes the patients less prone to knee pain and effusion but more prone to quadriceps muscle atrophy.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ruqaya Adnan Salih, Anmar B Al-Dewachi, Zaid Muayad Yassen, Saad Abdul-Razzak Ibrahim
{"title":"Patient's barrier to initiate insulin therapy for type 2 D.M.","authors":"Ruqaya Adnan Salih, Anmar B Al-Dewachi, Zaid Muayad Yassen, Saad Abdul-Razzak Ibrahim","doi":"10.1007/s11845-024-03826-y","DOIUrl":"https://doi.org/10.1007/s11845-024-03826-y","url":null,"abstract":"<p><strong>Background: </strong>Diabetes Mellitus is a health challenging of the century, more than 300 million people lives with diabetes, and it is one of the biggest global health concerns, awing to its complications. Good glycemic control is the cornerstone to decrease risk of type 2 diabetes complications. Even though, many people still have poor glycemic control which can be partly attributed to late insulin initiation, that can be challenging and forced by numbers of barriers. Identification and analysis of these barriers is crucial to find out effective way to overcome them.</p><p><strong>Aim: </strong>To assess patient's barriers to initiate insulin therapy among diabetic patients.</p><p><strong>Method: </strong>A case series study was conducted during the period extending from July 2023 to June 2024, and a total of 360 participants with type two diabetes were included in this study from four Family Medicine Health Centers. Collected data tabulated and analyzed using Excel sheets and applying the Statistical Package for the Social Sciences (SPSS) Version 24.</p><p><strong>Results: </strong>26% of the participants were 45-55 years age group, 40% has been diagnosed with diabetes for 5-10 years, and 66% have developed diabetic complications. Fear from hypoglycemia was the comments barrier to initiate insulin therapy and is seen in 84% of the participants.</p><p><strong>Conclusion: </strong>Many barriers have been identified to influence the initiation of insulin therapy, fear from hypoglycemia was found to be the most influencing barrier. Increasing patient's awareness of symptoms of hypoglycemia, and always take their meal after insulin injection can help to overcome hypoglycemia.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of programmed sedation care with conventional care in patients receiving mechanical ventilation for acute respiratory failure.","authors":"Jiantang Wang, Yuntao Li, Yujuan Han, Xinyu Yuan","doi":"10.1007/s11845-024-03825-z","DOIUrl":"https://doi.org/10.1007/s11845-024-03825-z","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study is to evaluate the effectiveness of planned sedation therapy in comparison to standard care for patients receiving mechanical ventilation for acute respiratory failure (ARF).</p><p><strong>Method: </strong>The research included a total of sixty individuals who underwent mechanical ventilation for acute respiratory failure (ARF). Utilizing the random number table method, these patients were randomized at random to either the planned sedation care group (Group PSC) or the conventional care group (Group C). The objective was to assess and contrast the impact of treatment on the two groups. Significantly shorter durations of mechanical ventilation, sedative use, ICU therapy, length of stay, incidence of delirium, and adverse events were observed in Group PSC compared with Group C (P < 0.05). A higher 1-month survival rate following mechanical ventilation, a higher post-intervention forced expiratory volume in one second (FEV1) as a percentage of the expected value, a higher post-intervention forced vital capacity (FVC), and a higher patient family care satisfaction rate were observed in Group PSC compared to Group C (P < 0.05).</p><p><strong>Conclusion: </strong>The scheduled administration of sedative therapy in patients receiving mechanical ventilation for acute respiratory failure (ARF) offers significant, reliable, and effective therapeutic benefits.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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