International Neurourology Journal最新文献

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Expanding Horizons: Robotic Surgery in Functional and Reconstructive Urology. 拓展视野:功能性和重建泌尿外科的机器人手术。
IF 2 3区 医学
International Neurourology Journal Pub Date : 2026-03-01 Epub Date: 2026-03-31 DOI: 10.5213/inj.2550196.098
Jisung Shim, Mimi Oh
{"title":"Expanding Horizons: Robotic Surgery in Functional and Reconstructive Urology.","authors":"Jisung Shim, Mimi Oh","doi":"10.5213/inj.2550196.098","DOIUrl":"10.5213/inj.2550196.098","url":null,"abstract":"<p><p>Robotic surgery has transformed functional and reconstructive urology (FRU) by improving operative precision, expanding reconstructive capabilities, and supporting favorable perioperative outcomes. Although robotic platforms have been widely adopted for oncologic urologic procedures, their use in FRU is still evolving, with ongoing refinements in technique, indications, and perioperative management. This review summarizes current applications of robotic surgery in FRU, highlights practical challenges and limitations, and discusses future directions for the field.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"30 1","pages":"11-27"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13053185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147627784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predicting Initial Trial Without Catheter Failure After Prostate Deobstruction Surgery Using Preoperative Urodynamics. 术前尿动力学预测前列腺除梗阻手术后无导管失效的初始试验。
IF 2.1 3区 医学
International Neurourology Journal Pub Date : 2025-12-01 Epub Date: 2025-11-04 DOI: 10.5213/inj.2550176.088
Jen-Hao Kuo, Ming-Syun Chuang, Hau-Chern Jan, Yu-Sheng Cheng, Yi-Hui Ho, Yao-Lin Kao, Kuen-Jer Tsai, Yin-Chien Ou
{"title":"Predicting Initial Trial Without Catheter Failure After Prostate Deobstruction Surgery Using Preoperative Urodynamics.","authors":"Jen-Hao Kuo, Ming-Syun Chuang, Hau-Chern Jan, Yu-Sheng Cheng, Yi-Hui Ho, Yao-Lin Kao, Kuen-Jer Tsai, Yin-Chien Ou","doi":"10.5213/inj.2550176.088","DOIUrl":"10.5213/inj.2550176.088","url":null,"abstract":"<p><strong>Purpose: </strong>Prostate deobstruction surgery is effective for relieving lower urinary tract symptoms in men with benign prostatic obstruction, yet some patients experience failure of the initial trial without catheter (TWOC) postoperatively and require recatheterization. This study aimed to identify clinical and urodynamic predictors of initial TWOC failure after prostate deobstruction surgery.</p><p><strong>Methods: </strong>A retrospective single-center study was conducted on 327 men who underwent prostate deobstruction surgery, including transurethral resection of the prostate, GreenLight laser photoselective vaporization, and holmium laser enucleation, at our institution from 2018 to 2024. Clinical characteristics, prostate volume, preoperative and postoperative uroflowmetry, and multichannel urodynamic parameters were evaluated. Initial TWOC failure was defined as recatheterization within 1 week of catheter removal. Logistic regression analysis was performed to identify predictive factors.</p><p><strong>Results: </strong>Among the 327 patients, 41 (12.5%) experienced initial TWOC failure. Uroflowmetry parameters improved significantly postoperatively. Multivariate analysis identified detrusor underactivity (DU) (odds ratio [OR], 2.773; P=0.012) and low bladder outlet obstruction (BOO) (OR, 2.881; P=0.041) as independent predictors. Patients with both risk factors exhibited a higher likelihood of initial TWOC failure (OR, 4.560; P=0.003), whereas those with high BOO and no DU showed lower risk (OR, 0.321; P=0.003). Notably, even among patients with high preoperative postvoid residual volume (PVR≥300 mL), those with high BOO and preserved detrusor contractility still demonstrated lower TWOC failure risk (OR, 0.154; P=0.018).</p><p><strong>Conclusion: </strong>Preoperative multichannel urodynamics enhance initial TWOC risk stratification and support individualized postoperative catheter management. Patients with DU and low BOO may require prolonged catheterization. In contrast, early catheter removal appears feasible in patients with high BOO and preserved detrusor function, even when preoperative PVR is elevated.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":" ","pages":"286-295"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12784056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145437968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transvaginal Mesh Surgery Is Sufficient to Repair Pelvic Organ Prolapse Compared to Laparoscopic Sacrocolpopexy: A Propensity Score Matching Analysis. 经阴道补片手术足以修复盆腔器官脱垂与腹腔镜骶colpop固定术:倾向评分匹配分析。
IF 2.1 3区 医学
International Neurourology Journal Pub Date : 2025-12-01 Epub Date: 2025-12-31 DOI: 10.5213/inj.2550092.046
Kenji Kuroda, Koetsu Hamamoto, Kazuki Kawamura, Ayako Masunaga, Hiroaki Kobayashi, Keiichi Ito
{"title":"Transvaginal Mesh Surgery Is Sufficient to Repair Pelvic Organ Prolapse Compared to Laparoscopic Sacrocolpopexy: A Propensity Score Matching Analysis.","authors":"Kenji Kuroda, Koetsu Hamamoto, Kazuki Kawamura, Ayako Masunaga, Hiroaki Kobayashi, Keiichi Ito","doi":"10.5213/inj.2550092.046","DOIUrl":"10.5213/inj.2550092.046","url":null,"abstract":"<p><strong>Purpose: </strong>Both laparoscopic sacrocolpopexy (LSC) and transvaginal mesh surgery (TVM) may provide favorable outcomes for patients with pelvic organ prolapse (POP). However, in our experience, LSC tends to be performed for severe POP and TVM for POP of a moderate or earlier stage. This study aimed to examine the postoperative results of the 2 groups including the preoperative parameters as closely as possible.</p><p><strong>Methods: </strong>We retrospectively evaluated 238 patients with POP who underwent LSC or TVM at National Defense Medical College Hospital between September 2014 and January 2024. In our hospital, 94 patients were treated by LSC, whereas 144 were treated by TVM. After using nearest-neighbor propensity score matching, the surgical outcomes were compared between the matched 76 patients treated with LSC and 76 treated with TVM.</p><p><strong>Results: </strong>To perform nearest-neighbor propensity score matching, the body mass index (BMI), POP stage, and number of laparotomies were used as explanatory variables. After propensity score matching, no significant differences in BMI, POP stage, and number of previous laparotomies were found between the matched LSC and TVM groups. Significant differences in age, blood loss, and operating time still existed even after propensity score matching. No significant differences in the occurrence of urinary incontinence or mesh exposure or prolapse recurrence were found between the matched LSC and TVM groups in all patients and patients with stage 4 POP. Moreover, no significant differences in the time to prolapse recurrence or urinary incontinence were found between the matched LSC and TVM groups (P=0.627 and P=0.235, respectively).</p><p><strong>Conclusion: </strong>Based on the analysis using nearest-neighbor propensity score matching, both surgical methods were effective treatment approaches of POP. TVM would be sufficient to treat POP given its shorter operative time and low complication rates.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"29 4","pages":"255-262"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12784060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145933314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urothelial Proteome Changes Underlying Overactive Bladder Associated With Bladder Outlet Obstruction. 膀胱过度活动与膀胱出口梗阻相关的尿路上皮蛋白组改变。
IF 2.1 3区 医学
International Neurourology Journal Pub Date : 2025-12-01 Epub Date: 2025-12-31 DOI: 10.5213/inj.2550248.124
Sang-Yeop Lee, Ji Yong Lee, Sung Ho Yun, Minji Lee, Dong-Eon Lee, Ji-Hyeon Min, Chung Lyul Lee, Gun-Hwa Kim, Ju Hyun Shin
{"title":"Urothelial Proteome Changes Underlying Overactive Bladder Associated With Bladder Outlet Obstruction.","authors":"Sang-Yeop Lee, Ji Yong Lee, Sung Ho Yun, Minji Lee, Dong-Eon Lee, Ji-Hyeon Min, Chung Lyul Lee, Gun-Hwa Kim, Ju Hyun Shin","doi":"10.5213/inj.2550248.124","DOIUrl":"10.5213/inj.2550248.124","url":null,"abstract":"<p><strong>Purpose: </strong>Overactive bladder (OAB) in men with bladder outlet obstruction (BOO) due to benign prostatic hyperplasia (BPH) represents a major therapeutic challenge, as symptoms often persist even after surgical relief of obstruction. The underlying molecular mechanisms, however, remain poorly defined. The aim of this study was to identify differentially expressed proteins in the urothelial tissues of patients with BOO-related OAB using a proteomic approach.</p><p><strong>Methods: </strong>Bladder urothelial tissues were obtained via cold-cup biopsy during transurethral resection of the prostate in patients with BPH. Patients were classified into OAB and non-OAB groups. Proteomic profiling was conducted using liquid chromatography-tandem mass spectrometry, followed by functional annotation and pathway enrichment analyses with the Ingenuity Pathway Analysis and Gene Ontology tools.</p><p><strong>Results: </strong>Proteomic analysis identified 1,510 proteins, of which 133 were differentially expressed proteins in patients with OAB compared with the non-OAB group. Dysregulated pathways included cytoskeletal remodeling, Rho GTPase signaling, serotonergic signaling, and immune responses. Structural proteins such as ACTA2, CFL2, MYLK, and PPP1R12B were markedly downregulated, whereas GNA13 and multiple inflammatory mediators were upregulated. Functional analysis confirmed the enrichment of neurotransmitter catabolic processes, immune responses, and impaired cell-cell contact, suggesting structural disorganization and aberrant epithelial signaling in the OAB group.</p><p><strong>Conclusion: </strong>BOO-related OAB is associated with distinct molecular disturbances in cytoskeletal organization, neurotransmitter pathways, and immune responses. These proteomic findings provide novel insights into disease pathophysiology and highlight potential molecular targets for biomarker discovery and therapeutic interventions.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"29 4","pages":"226-235"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12784054/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145933326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the Long-term Treatment Outcome Between Pubovaginal and Transobturator Suburethral Sling for Stress Urinary Incontinence in Women. 阴部阴道与经膜尿道下悬吊治疗女性压力性尿失禁的长期疗效比较。
IF 2.1 3区 医学
International Neurourology Journal Pub Date : 2025-12-01 Epub Date: 2025-11-04 DOI: 10.5213/inj.2550078.039
Yi Hsuan Wu, Yuan-Hong Jiang, Sheng-Fu Chen, Hann-Chorng Kuo
{"title":"Comparison of the Long-term Treatment Outcome Between Pubovaginal and Transobturator Suburethral Sling for Stress Urinary Incontinence in Women.","authors":"Yi Hsuan Wu, Yuan-Hong Jiang, Sheng-Fu Chen, Hann-Chorng Kuo","doi":"10.5213/inj.2550078.039","DOIUrl":"10.5213/inj.2550078.039","url":null,"abstract":"<p><strong>Purpose: </strong>Stress urinary incontinence (SUI) affects women worldwide, and surgery remains important for those who do not respond to conservative management.</p><p><strong>Methods: </strong>We retrospectively reviewed the medical records of 533 female patients with mixed urinary incontinence and predominant SUI treated at a medical center. Some patients may have had stage 3 or higher cystocele and underwent concomitant anterior colporrhaphy. Patients were divided into 4 groups: pubovaginal sling (PVS) alone, PVS with colporrhaphy, transobturator suburethral sling (TOT) alone, and TOT with colporrhaphy. The primary outcome was the long-term cumulative success rate in each group, and a successful outcome was defined as being dry or using fewer than 1 pad per day. The secondary outcomes included subjective postoperative lower urinary tract symptoms and various perioperative complications.</p><p><strong>Results: </strong>The long-term cumulative success rates of the PVS groups, with or without colporrhaphy, were significantly higher than those of the TOT groups, with or without colporrhaphy (P<0.001). The group receiving PVS with concurrent colporrhaphy demonstrated the highest success rate, followed by PVS alone, TOT with colporrhaphy, and TOT alone (P=0.003). In addition, the highest rate of persistent overactive bladder symptoms was observed in the TOT-alone group (P<0.001).</p><p><strong>Conclusion: </strong>This study suggests that PVS is superior to TOT in controlling incontinence symptoms and achieving long-term success. Concurrent colporrhaphy may also contribute to improved anti-incontinence outcomes.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"29 4","pages":"248-254"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12784059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145933303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Do Alpha-Blockers and 5-Alpha Reductase Inhibitors Increase Dementia Risk? A Network Meta-analysis. α受体阻滞剂和5- α还原酶抑制剂会增加痴呆风险吗?网络元分析。
IF 2.1 3区 医学
International Neurourology Journal Pub Date : 2025-12-01 Epub Date: 2025-12-31 DOI: 10.5213/inj.2550174.087
Karmenia Jessica Kurnia Niaga, Fransiskus Xaverius Rinaldi, Nathania Nathania, Pedro Arruda Supinto, Stevan Kristian Lionardi, Rivan Yo, Agoes Wilyono, Parningotan Yosi Silalahi
{"title":"Do Alpha-Blockers and 5-Alpha Reductase Inhibitors Increase Dementia Risk? A Network Meta-analysis.","authors":"Karmenia Jessica Kurnia Niaga, Fransiskus Xaverius Rinaldi, Nathania Nathania, Pedro Arruda Supinto, Stevan Kristian Lionardi, Rivan Yo, Agoes Wilyono, Parningotan Yosi Silalahi","doi":"10.5213/inj.2550174.087","DOIUrl":"10.5213/inj.2550174.087","url":null,"abstract":"<p><strong>Purpose: </strong>Alpha-blockers and 5-alpha reductase inhibitors (5ARIs) are well-established treatments for symptoms of benign prostatic hyperplasia (BPH). Despite their therapeutic benefits, concerns have been raised regarding a potential association between these medications and an increased risk of dementia. However, current evidence remains inconsistent, highlighting the need for further evaluation. This study aims to assess the potential dementia risk among patients receiving alpha-blockers and 5ARIs.</p><p><strong>Methods: </strong>Following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) guidelines (PROSPERO CRD42025643431), 7 databases were systematically searched through December 2024 for studies examining the association between alpha-blockers or 5ARIs and dementia risk in patients with BPH. Risk of bias was assessed using the ROBINS-I (Risk of Bias in Non-randomized Studies of Interventions) tool. A Bayesian network meta-analysis was performed to estimate risk ratios with 95% credible intervals and to generate surface under the cumulative ranking curve (SUCRA) values.</p><p><strong>Results: </strong>Five multicenter studies involving 3,650,434 patients (mean age, 71.1 years) and demonstrating an overall low risk of bias were included. The network analysis indicated that neither alpha-blockers nor 5ARIs were significantly associated with an increased risk of dementia compared with no treatment. However, SUCRA values suggested a relatively higher probability of dementia risk for 5ARIs (finasteride and dutasteride), followed by tamsulosin, doxazosin, terazosin, and alfuzosin.</p><p><strong>Conclusion: </strong>This study found no significant association between the use of alpha-blockers or 5ARIs and increased dementia risk. These findings may assist clinicians in making more informed prescribing decisions, particularly for older male patients with BPH. Further large-scale research with extended follow-up periods is needed to strengthen the evidence across all BPH medications.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"29 4","pages":"236-247"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12784055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145933339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perioperative Outcomes in Simple Cystectomy for Neurogenic Lower Urinary Tract Dysfunction: A Comparison of Surgical Approach, Surgical Teams, and Alvimopan Use. 单纯膀胱切除术治疗神经源性下尿路功能障碍的围手术期疗效:手术入路、手术小组和使用阿尔维莫泮的比较。
IF 2.1 3区 医学
International Neurourology Journal Pub Date : 2025-12-01 Epub Date: 2025-12-31 DOI: 10.5213/inj.2550116.058
Vatsala Mundra, Christina Sze, Samuel Gold, Maude Carmel, Gary Lemack, Ramy Goueli
{"title":"Perioperative Outcomes in Simple Cystectomy for Neurogenic Lower Urinary Tract Dysfunction: A Comparison of Surgical Approach, Surgical Teams, and Alvimopan Use.","authors":"Vatsala Mundra, Christina Sze, Samuel Gold, Maude Carmel, Gary Lemack, Ramy Goueli","doi":"10.5213/inj.2550116.058","DOIUrl":"10.5213/inj.2550116.058","url":null,"abstract":"<p><strong>Purpose: </strong>Limited data exist on factors influencing surgical outcomes in simple cystectomy for refractory neurogenic lower urinary tract dysfunction (NLUTD). We evaluated the impact of alvimopan use, surgical approach (robotic vs. open), and single vs. multiple surgeons on peri- and postoperative outcomes.</p><p><strong>Methods: </strong>We conducted a retrospective study of patients undergoing simple cystectomy for refractory NLUTD. Patient demographics, surgical details, and postoperative outcomes, including bowel function recovery, postoperative ileus, nasogastric tube use, and total parenteral nutrition use, were analyzed.</p><p><strong>Results: </strong>A total of 44 patients were included in the study, with 68% being female. The median age was 57 years, and the median body mass index was 28.3 kg/m2. The majority were Caucasian (86%) with spinal cord injury (55%) history. In comparing single-surgeon versus multiple-surgeon procedures, the latter had significantly higher estimated blood loss. Thirty-three patients (73%) received alvimopan, with no significant differences between alvimopan and nonalvimopan groups in operative and postoperative factors.</p><p><strong>Conclusion: </strong>NLUTD patients undergoing simple cystectomy represent a distinct surgical cohort. While multiple-surgeon procedures resulted in greater blood loss, they did not affect other perioperative outcomes. Additionally, alvimopan did not significantly improve bowel function recovery or reduce postoperative ileus, likely due to underlying neurogenic bowel dysfunction.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"29 4","pages":"270-276"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12784061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145933334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accuracy of Portable Ultrasound Measurement of the Bladder Volume Using the Manual Fanning Scan and Traditional Motorized Scan Methods. 手摇扫描与传统机动扫描方法在便携式超声膀胱体积测量中的准确性。
IF 2.1 3区 医学
International Neurourology Journal Pub Date : 2025-12-01 Epub Date: 2025-12-31 DOI: 10.5213/inj.2550190.095
Hyun Ju Jeong, Seung-June Oh
{"title":"Accuracy of Portable Ultrasound Measurement of the Bladder Volume Using the Manual Fanning Scan and Traditional Motorized Scan Methods.","authors":"Hyun Ju Jeong, Seung-June Oh","doi":"10.5213/inj.2550190.095","DOIUrl":"10.5213/inj.2550190.095","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the accuracy of portable ultrasound bladder scanner (PUBS) for measuring bladder volume (BV) using manual fanning scan (MFS) and traditional motorized scan (TMS) methods.</p><p><strong>Methods: </strong>Patients with lower urinary tract symptoms who underwent a urodynamic study at the urology outpatient clinic from October to December 2024 were prospectively enrolled. BV was measured using TMS-type (TMS-BV) and MFS-type (MFS-BV) PUBS prior to free uroflowmetry. True BV (T-BV) was defined as the sum of the voided volume and the postvoid residual volume drained through the urethral catheter after voiding. TMS-BV and MFS-BV were compared and analyzed against T-BV.</p><p><strong>Results: </strong>Data from 39 patients (30 males and 9 females; mean age, 65.3±14.8 years) were analyzed. TMS-BV (230.9±157.9 mL) and MFS-BV (222.6±154.2 mL) did not differ significantly from T-BV (230.6±156.6 mL) (P>0.05). Comparison of the percentage of difference in volume between TMS-BV and MFS-BV across 100-mL BV ranges revealed no significant difference (P>0.05). The mean difference between TMS-BV and T-BV (0.2±50.2) did not differ significantly from the mean difference between MFS-BV and T-BV (-8.0±69.1) (P>0.05). The correlation between TMS-BV and T-BV (R2=0.90) was stronger than that between MFS-BV and T-BV (R2=0.81).</p><p><strong>Conclusion: </strong>The correlation between MFS-type PUBS and T-BV was lower than that between TMS-type PUBS and T-BV. However, the measurement accuracy of BV was similar using both methods.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"29 4","pages":"296-301"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12784057/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145933281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mediating Effect of Serum Uric Acid in the Association Between Nocturia and Mortality. 血清尿酸在夜尿症与死亡率之间的中介作用。
IF 2.1 3区 医学
International Neurourology Journal Pub Date : 2025-12-01 Epub Date: 2025-12-31 DOI: 10.5213/inj.2550126.063
Sung Jin Kim, Sung Gon Park, Sahyun Pak, Ohseong Kwon, Young Goo Lee, Sung Tae Cho
{"title":"Mediating Effect of Serum Uric Acid in the Association Between Nocturia and Mortality.","authors":"Sung Jin Kim, Sung Gon Park, Sahyun Pak, Ohseong Kwon, Young Goo Lee, Sung Tae Cho","doi":"10.5213/inj.2550126.063","DOIUrl":"10.5213/inj.2550126.063","url":null,"abstract":"<p><strong>Purpose: </strong>Nocturia is increasingly recognized as a natural consequence of aging and is commonly observed in the context of systemic dysfunction, with growing evidence linking it to elevated mortality risk. This study aims to elucidate whether serum uric acid (sUA) acts as a mediator in this associative pathway.</p><p><strong>Methods: </strong>This study used population-based data from 2005 to 2014 to investigate the association between nocturia and mortality, incorporating sUA as a potential mediator. Using data from 12,522 participants, sUA levels were categorized into quartiles (Q1-Q4) to assess dose-response relationships in the context of nocturia and mortality.</p><p><strong>Results: </strong>Participants in higher sUA quartiles were older and exhibited a greater burden of metabolic risk factors, including higher body mass index, waist circumference, and blood pressure. After adjustment, Cox regression analysis revealed a significant association between nocturia and increased all-cause and cardiovascular mortality. Restricted cubic spline regression indicated a J-shaped association between elevated sUA and increased mortality. Additionally, mediation analysis demonstrated that sUA partly mediated the relationship between nocturia and mortality.</p><p><strong>Conclusion: </strong>Nocturia independently predicts mortality, irrespective of metabolic status and sUA levels. These findings underscore the pivotal mediating role of sUA, highlighting the necessity of an integrated approach to nocturia management. Future research should prioritize interventional strategies that target metabolic dysfunction as a means to reduce nocturia-associated mortality risk.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"29 4","pages":"277-285"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12784058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145933276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current Status of Clean Intermittent Catheterization Education in South Korea. 韩国清洁间歇导尿教育现状
IF 2.1 3区 医学
International Neurourology Journal Pub Date : 2025-12-01 Epub Date: 2025-12-31 DOI: 10.5213/inj.2550108.054
Jung Hyun Shin, Sangrak Bae, Jang Hwan Kim, Sun-Ouck Kim
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