International Neurourology Journal最新文献

{"title":"The Evolving Landscape of Urology.","authors":"Khae Hawn Kim","doi":"10.5213/inj.2424edi05","DOIUrl":"10.5213/inj.2424edi05","url":null,"abstract":"","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 Suppl 2","pages":"S63-64"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11627227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Public Views on Managing Benign Prostatic Hyperplasia-Related Voiding Dysfunction: Potential Applications of Digital Therapeutic.","authors":"So Jin Lee, Jong Mok Park, Jung Yoon Kim","doi":"10.5213/inj.2448398.199","DOIUrl":"10.5213/inj.2448398.199","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to explore the potential of digital therapeutics in managing voiding dysfunction associated with benign prostatic hyperplasia (BPH). To achieve this, we collected and analyzed news and community data from major Korean platforms to assess the trends in media and community discussions and examine how digital therapeutics can contribute to personalized care and support self-management for patients with BPH-related voiding dysfunction.</p><p><strong>Methods: </strong>Data was collected over a 3-year period from October 2021 to September 2024 using the keywords 'prostate,' 'urinary,' and 'treatment.' Key terms and patterns were then identified through word frequency analysis, TF-IDF (term frequency-inverse document frequency) analysis, and N-gram analysis to examine the potential applicability of digital therapeutics in this area.</p><p><strong>Results: </strong>The news data primarily focused on expert-oriented medical information related to the treatment, surgical options, and diagnosis of BPH. In contrast, community data centered on discussions about everyday symptoms and solutions, such as urinary issues and self-care tips. This suggests that patients are particularly interested in practical problem-solving and selfmanagement strategies.</p><p><strong>Conclusion: </strong>This study suggests that digital therapeutics can empower patients with BPH to self-manage their urinary disorders through personalized management tools. Future research can be done to focus on empirically examining the clinical validity and practical applicability of digital therapeutics for BPH through clinical trials.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 Suppl 2","pages":"S90-96"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11627228/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Large Language Models and the Metaverse for Urologic Applications: Potential, Challenges, and the Path Forward.","authors":"Hyung Jun Park, Eun Joung Kim, Jung Yoon Kim","doi":"10.5213/inj.2448402.201","DOIUrl":"10.5213/inj.2448402.201","url":null,"abstract":"<p><p>The metaverse, a 3-dimensional digital platform that enables users to interact and engage in realistic virtual activities beyond time and space limitations, has garnered significant investment across industries, particularly in healthcare. In the medical field, the metaverse shows promise as a digital therapeutic platform to enhance interaction between medical professionals and patients. Concurrently, generative artificial intelligence, especially large language models, is being integrated into healthcare for applications in data analysis, image recognition, and natural language processing. In urology, large language models (LLMs) support are increasingly used in urology for tasks such as image diagnosis, data processing, patient education, and treatment assistance in order to provide significant support in clinical settings. By combining LLMs with the immersive capabilities of the metaverse, new possibilities emerge to improve urologic treatment in areas that require consistent treatments, habit formation, and long-term management. This paper reviews current research and applications of LLMs in urology, discusses the challenges associated with their use including data quality, bias, security, and ethical issues, and explores the need for regulatory standards. Furthermore, it highlights the potential of a metaverse-based digital platform to improve urologic care and streamline information exchange to maximize the benefits of this integrated approach in future healthcare applications.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 Suppl 2","pages":"S65-73"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11627225/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Machine Learning Models for the Noninvasive Diagnosis of Bladder Outlet Obstruction and Detrusor Underactivity in Men With Lower Urinary Tract Symptoms.","authors":"Hyungkyung Shin, Kwang Jin Ko, Wei-Jin Park, Deok Hyun Han, Ikjun Yeom, Kyu-Sung Lee","doi":"10.5213/inj.2448360.180","DOIUrl":"10.5213/inj.2448360.180","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to develop and evaluate machine learning models, specifically CatBoost and extreme gradient boosting (XGBoost), for diagnosing lower urinary tract symptoms (LUTS) in male patients. The objective is to differentiate between bladder outlet obstruction (BOO) and detrusor underactivity (DUA) using a comprehensive dataset that includes patient-reported outcomes, uroflowmetry measurements, and ultrasound-derived features.</p><p><strong>Methods: </strong>The dataset used in this study was collected from male patients aged 40 and older who presented with LUTS and sought treatment at the urology department of Samsung Medical Center. We developed and trained CatBoost and XGBoost models using this dataset. These models incorporated features like prostate size, voiding parameters, and responses from questionnaires. Their performance was assessed using standard metrics such as accuracy, precision, recall, F1-score, and area under the receiver operating characteristic curve (AUROC).</p><p><strong>Results: </strong>The results indicated that the CatBoost models displayed greater sensitivity, rendering them effective for initial screenings by accurately identifying true positive cases. Conversely, the XGBoost models showed higher specificity and precision, making them more suitable for confirming diagnoses and reducing false positives. In terms of overall performance for both BOO and DUA, XGBoost surpassed CatBoost, achieving an AUROC of 0.826 and 0.819, respectively.</p><p><strong>Conclusion: </strong>Integrating these machine learning models into the diagnostic workflow for LUTS can significantly enhance clinical decision-making by offering noninvasive, cost-effective, and patient-friendly diagnostic alternatives. The combined application of CatBoost and XGBoost models has the potential to improve diagnostic accuracy and provide customized treatment plans for patients, ultimately leading to better clinical outcomes.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 Suppl 2","pages":"S74-81"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11627226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Deep Learning-Based Predictive Model for Improvement after Holmium Laser Enucleation of the Prostate According to Detrusor Contractility.","authors":"Jong Hoon Lee, Jung Hyun Kim, Myung Jin Chung, Kyu-Sung Lee, Kwang Jin Ko","doi":"10.5213/inj.2448362.181","DOIUrl":"10.5213/inj.2448362.181","url":null,"abstract":"<p><strong>Purpose: </strong>Predicting improvements in voiding symptoms following deobstructive surgery for male lower urinary tract symptoms/benign prostatic hyperplasia (LUTS/BPH) is challenging when detrusor contractility is impaired. This study aimed to develop an artificial intelligence model that predicts symptom improvement after holmium laser enucleation of the prostate (HoLEP), focusing on changes in maximum flow rate (MFR) and voiding efficiency (VE) 1-month postsurgery.</p><p><strong>Methods: </strong>We reviewed 1,933 patients who underwent HoLEP at Samsung Medical Center from July 2008 to January 2024. The study employed a deep neural network (DNN) for multiclass classification to predict changes in MFR and VE, each divided into 3 categories. For comparison, additional machine learning (ML) models such as extreme gradient boosting, random forest classification, and support vector machine were utilized. To address class imbalance, we applied the least squares method and multitask learning.</p><p><strong>Results: </strong>A total of 1,142 patients with complete data were included in the study, with 992 allocated for model training and 150 for external validation. In predicting MFR, the DNN achieved a microaverage area under the receiver operating characteristic curve (AUC) of 0.884±0.006, sensitivity of 0.783±0.020, and specificity of 0.891±0.010. For VE prediction, the microaverage AUC was 0.817±0.007, with sensitivity and specificity values of 0.660±0.014 and 0.830±0.007, respectively. These results indicate that the DNN's predictive performance was superior to that of other ML models.</p><p><strong>Conclusion: </strong>The DNN model provides detailed and accurate predictions for recovery after HoLEP, providing valuable insights for clinicians managing patients with LUTS/BPH.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 Suppl 2","pages":"S82-89"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11627230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lower Urinary Tract Symptoms in Mental Illness: A Topic Modeling Approach to Online Mental Health Communities.","authors":"Jung Eun Yu, Jung Yoon Kim","doi":"10.5213/Inj.2448396.198","DOIUrl":"10.5213/Inj.2448396.198","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to provide foundational data to enhance integrated interventions by gaining an in-depth understanding of the perceptions of patients experiencing both mental illness and lower urinary tract symptoms (LUTS), which carry a high risk of comorbidity and potential mutual exacerbation.</p><p><strong>Methods: </strong>Data were collected from a large online mental health community in South Korea, active among individuals with mental illness and their families (as of October 21, 2024: 113,060 members and 368,352 posts). Posts containing the keywords 'pee' or 'urine' (a total of 986 posts) were analyzed including their titles, content, and categories. Analyses included word cloud, latent Dirichlet allocation topic modeling, category frequency analysis, and qualitative analysis.</p><p><strong>Results: </strong>The findings indicate that among individuals with mental illness, LUTS are perceived as side effects of psychiatric medications and regarded as inevitable. Many patients attempted self-regulation or discontinuation of medication instead of seeking urological treatment, but these attempts often led to failure. The study revealed that participants used the community to explore the relationship between LUTS and mental illness. LUTS had negative impacts on family and social life, and urinary incontinence exacerbated emotional distress such as self-blame and despair.</p><p><strong>Conclusion: </strong>Patients with mental illness experiencing LUTS often engage in self-regulation or discontinuation of medication. It underscores the need for accurate information and warnings about risks. As these patients endure discomfort and frustration in daily life, symptom deterioration is likely and necessitates proactive urological intervention to improve their quality of life. This study enhances understanding of the impact of co-occurring mental illness and LUTS and highlights the need for proper information and guidance. However, it has limitations including reliance on self-reported data and limited sample representativeness. Future research can address these issues by linking medical diagnoses with objective data and expanding the sample size.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 Suppl 2","pages":"S97-105"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11627224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Public Perceptions of Male Hormone Levels and Prostate Health: A Text Mining Analysis of South Korean Media and Online Communities.","authors":"So Jin Lee, Jung Yoon Kim","doi":"10.5213/inj.2448320.160","DOIUrl":"10.5213/inj.2448320.160","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study is to identify social perceptions and public concerns related to male hormone levels and prostate cancer. To do so, we analyzed news and community data from Naver, Daum, and Google, the three most active social media platforms in South Korea, to explore how male hormone levels and benign prostatic hyperplasia (BPH) are covered in the media and discussed within online communities.</p><p><strong>Methods: </strong>We analyzed three years of data from community discussions and news articles from July 2021 to June 2024. Text mining techniques were used to collect data with the keyword 'male hormone levels' to understand the portrayal of these issues in news and online communities as well as the public's social perceptions and concerns.</p><p><strong>Results: </strong>The analysis showed that news coverage of 'male hormone levels' initially drew public attention by highlighting information related to celebrities and events while discussion on 'prostate enlargement' largely focused on medical treatments and information. The online community served as a platform where news-triggered issues were rediscussed through personal experiences and opinions, thus influencing public perceptions. However, the community discussions leaned more towards sexual dysfunction rather than prostate enlargement. These findings suggest that while news and online communities shape public awareness in different way, they both contribute to shaping social understanding of male hormone level and BPH.</p><p><strong>Conclusion: </strong>This study highlights the significant roles that news and online communities play in shaping social perceptions of male hormone levels and BPH. However, sensationalism in media coverage may lead to biased information and reinforce false stereotypes. Future studies can be done to incorporate data from diverse cultural contexts and extend the data collection period to further explore shifts in public perceptions and the evolution of social discussions surrounding male hormone levels and BPH.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 Suppl 2","pages":"S106-113"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11627223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vasectomy Discussions in South Korea: Central Themes and Public Interest on Question-and-Answer Social Platforms.","authors":"Ho Seong Kang, Jung Yoon Kim","doi":"10.5213/inj.2448324.162","DOIUrl":"10.5213/inj.2448324.162","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this paper is to explore public perceptions and key issues related to vasectomy in South Korea. In particular, this paper seeks to analyze how vasectomy is discussed on question-and-answer (Q&A) social platforms including NAVER Jisik iN (knowledge exchange service between NAVER users) and to identify topics that capture public interest.</p><p><strong>Methods: </strong>In this study, based on data collected on NAVER Jisik iN from July 2019 to July 2024 with the keyword 'vasectomy,' this paper performs a co-occurrence matrix analysis on the Q&A data to identify key terms related to the topic. By applying connection centrality and community detection techniques, this paper visualizes and examines the network graph to uncover relationships between words and identify the primary topics of discussion.</p><p><strong>Results: </strong>The co-occurrence matrix analysis reveals that keywords such as 'surgery,' 'vasectomy,' and 'contraception' play a central role in discussions about vasectomies. Both the Q&A data highlight the vasectomy procedure and contraceptive effectiveness as primary topics of discussion. The visualization graphs intuitively display the centrality and strength of connections between these keywords, as well as the interrelatedness of topics through distinct community groups.</p><p><strong>Conclusion: </strong>The analysis shows that the questions primarily focused on the surgical procedure, while the answers were more concerned with contraceptive effectiveness and physiological aspects. These results suggest that the public's interest in vasectomy is closely linked to its effectiveness, potential side effects, and related social issues.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 Suppl 2","pages":"S114-128"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11627229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Alpha-1 Adrenoreceptor Antagonist Use and Cognitive Impairment: A Systematic Review.","authors":"Ryan Kingsley, Sara Tyree, Dhairya Jarsania, Christopher Edquist, Allyson Palmer, Dana Gerberi, Robert Wilfahrt, Sandeep Pagali","doi":"10.5213/inj.2448266.133","DOIUrl":"10.5213/inj.2448266.133","url":null,"abstract":"<p><p>Alpha-1 adrenergic receptor (α1-AR) antagonists are commonly used for management of benign prostatic hyperplasia or hypertension. Some studies have shown a potential link between α1-AR antagonist use and cognitive impairment. Given the conflicting data surrounding α1-AR antagonists association with cognitive dysfunction, we aim to systematically review the association of cognitive dysfunction with α1-AR antagonist use to aid clinician decision both with medication initiation and continuation. A systematic review was performed following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. We searched Ovid Cochrane, Ovid Embase, Ovid MEDLINE, Scopus, and Web of Science on March 7, 2023, with an update run on January 22, 2024. The primary outcome was cognitive dysfunction. We used Cochrane risk of bias for randomized controlled trials (RCTs) and MINORS (Methodological Index for Non-Randomized Studies) criteria for non-RCTs to evaluate study quality. This study was registered with PROSPERO (CRD42024505751). We identified 7 studies for our systematic review (3 RCTs, 4 non-RCTs). Tamsulosin was the most studied medication (6 of 7 studies). Tamsulosin was associated with no cognitive dysfunction in 2 RCTs, increased risk for dementia in 2 non-RCTs, no change in cognition in 1 non-RCT, and decreased risk for dementia in 1 non-RCT. Among 3 non-RCTs analyzing alfuzosin, it was associated with decreased risk of or no association with dementia in 2 studies and increased risk for dementia in 1 study. Doxazosin, prazosin, and terazosin were neutral or showed a negative risk for dementia. Our systematic review did not show a convincing causal association between α1-AR antagonists, including tamsulosin, and cognitive dysfunction. Considering the existing literature, it is appropriate to use α1-AR antagonists without concern for cognitive dysfunction. Future research, through robust study designs considering the multifactorial nature of cognitive dysfunction, is required to further evaluate this association.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 3","pages":"171-180"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11450241/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Frontiers of Urological Science.","authors":"Sung-Jong Eun","doi":"10.5213/inj.2424edi04","DOIUrl":"10.5213/inj.2424edi04","url":null,"abstract":"","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 3","pages":"169-170"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11450245/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}