International Neurourology Journal最新文献

{"title":"Vasectomy Discussions in South Korea: Central Themes and Public Interest on Question-and-Answer Social Platforms.","authors":"Ho Seong Kang, Jung Yoon Kim","doi":"10.5213/inj.2448324.162","DOIUrl":"10.5213/inj.2448324.162","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this paper is to explore public perceptions and key issues related to vasectomy in South Korea. In particular, this paper seeks to analyze how vasectomy is discussed on question-and-answer (Q&A) social platforms including NAVER Jisik iN (knowledge exchange service between NAVER users) and to identify topics that capture public interest.</p><p><strong>Methods: </strong>In this study, based on data collected on NAVER Jisik iN from July 2019 to July 2024 with the keyword 'vasectomy,' this paper performs a co-occurrence matrix analysis on the Q&A data to identify key terms related to the topic. By applying connection centrality and community detection techniques, this paper visualizes and examines the network graph to uncover relationships between words and identify the primary topics of discussion.</p><p><strong>Results: </strong>The co-occurrence matrix analysis reveals that keywords such as 'surgery,' 'vasectomy,' and 'contraception' play a central role in discussions about vasectomies. Both the Q&A data highlight the vasectomy procedure and contraceptive effectiveness as primary topics of discussion. The visualization graphs intuitively display the centrality and strength of connections between these keywords, as well as the interrelatedness of topics through distinct community groups.</p><p><strong>Conclusion: </strong>The analysis shows that the questions primarily focused on the surgical procedure, while the answers were more concerned with contraceptive effectiveness and physiological aspects. These results suggest that the public's interest in vasectomy is closely linked to its effectiveness, potential side effects, and related social issues.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 Suppl 2","pages":"S114-128"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11627229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lower Urinary Tract Symptoms in Mental Illness: A Topic Modeling Approach to Online Mental Health Communities.","authors":"Jung Eun Yu, Jung Yoon Kim","doi":"10.5213/Inj.2448396.198","DOIUrl":"10.5213/Inj.2448396.198","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to provide foundational data to enhance integrated interventions by gaining an in-depth understanding of the perceptions of patients experiencing both mental illness and lower urinary tract symptoms (LUTS), which carry a high risk of comorbidity and potential mutual exacerbation.</p><p><strong>Methods: </strong>Data were collected from a large online mental health community in South Korea, active among individuals with mental illness and their families (as of October 21, 2024: 113,060 members and 368,352 posts). Posts containing the keywords 'pee' or 'urine' (a total of 986 posts) were analyzed including their titles, content, and categories. Analyses included word cloud, latent Dirichlet allocation topic modeling, category frequency analysis, and qualitative analysis.</p><p><strong>Results: </strong>The findings indicate that among individuals with mental illness, LUTS are perceived as side effects of psychiatric medications and regarded as inevitable. Many patients attempted self-regulation or discontinuation of medication instead of seeking urological treatment, but these attempts often led to failure. The study revealed that participants used the community to explore the relationship between LUTS and mental illness. LUTS had negative impacts on family and social life, and urinary incontinence exacerbated emotional distress such as self-blame and despair.</p><p><strong>Conclusion: </strong>Patients with mental illness experiencing LUTS often engage in self-regulation or discontinuation of medication. It underscores the need for accurate information and warnings about risks. As these patients endure discomfort and frustration in daily life, symptom deterioration is likely and necessitates proactive urological intervention to improve their quality of life. This study enhances understanding of the impact of co-occurring mental illness and LUTS and highlights the need for proper information and guidance. However, it has limitations including reliance on self-reported data and limited sample representativeness. Future research can address these issues by linking medical diagnoses with objective data and expanding the sample size.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 Suppl 2","pages":"S97-105"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11627224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Alpha-1 Adrenoreceptor Antagonist Use and Cognitive Impairment: A Systematic Review.","authors":"Ryan Kingsley, Sara Tyree, Dhairya Jarsania, Christopher Edquist, Allyson Palmer, Dana Gerberi, Robert Wilfahrt, Sandeep Pagali","doi":"10.5213/inj.2448266.133","DOIUrl":"10.5213/inj.2448266.133","url":null,"abstract":"<p><p>Alpha-1 adrenergic receptor (α1-AR) antagonists are commonly used for management of benign prostatic hyperplasia or hypertension. Some studies have shown a potential link between α1-AR antagonist use and cognitive impairment. Given the conflicting data surrounding α1-AR antagonists association with cognitive dysfunction, we aim to systematically review the association of cognitive dysfunction with α1-AR antagonist use to aid clinician decision both with medication initiation and continuation. A systematic review was performed following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. We searched Ovid Cochrane, Ovid Embase, Ovid MEDLINE, Scopus, and Web of Science on March 7, 2023, with an update run on January 22, 2024. The primary outcome was cognitive dysfunction. We used Cochrane risk of bias for randomized controlled trials (RCTs) and MINORS (Methodological Index for Non-Randomized Studies) criteria for non-RCTs to evaluate study quality. This study was registered with PROSPERO (CRD42024505751). We identified 7 studies for our systematic review (3 RCTs, 4 non-RCTs). Tamsulosin was the most studied medication (6 of 7 studies). Tamsulosin was associated with no cognitive dysfunction in 2 RCTs, increased risk for dementia in 2 non-RCTs, no change in cognition in 1 non-RCT, and decreased risk for dementia in 1 non-RCT. Among 3 non-RCTs analyzing alfuzosin, it was associated with decreased risk of or no association with dementia in 2 studies and increased risk for dementia in 1 study. Doxazosin, prazosin, and terazosin were neutral or showed a negative risk for dementia. Our systematic review did not show a convincing causal association between α1-AR antagonists, including tamsulosin, and cognitive dysfunction. Considering the existing literature, it is appropriate to use α1-AR antagonists without concern for cognitive dysfunction. Future research, through robust study designs considering the multifactorial nature of cognitive dysfunction, is required to further evaluate this association.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 3","pages":"171-180"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11450241/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Frontiers of Urological Science.","authors":"Sung-Jong Eun","doi":"10.5213/inj.2424edi04","DOIUrl":"10.5213/inj.2424edi04","url":null,"abstract":"","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 3","pages":"169-170"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11450245/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The International Consultation on Incontinence Questionnaire Short Form as a Substitute for 1-Hour Pad Weight Testing in the Evaluation of Urinary Incontinence in Patients With Pelvic Organ Prolapse Undergoing Surgery.","authors":"Kenji Kuroda, Koetsu Hamamoto, Kazuki Kawamura, Ayako Masunaga, Hiroaki Kobayashi, Akio Horiguchi, Keiichi Ito","doi":"10.5213/inj.2448234.117","DOIUrl":"10.5213/inj.2448234.117","url":null,"abstract":"<p><strong>Purpose: </strong>Stress urinary incontinence is a postoperative complication occurring in patients with pelvic organ prolapse (POP). Although the 1-hour pad test measures the degree of urinary incontinence qualitatively and quantitatively, some elderly women undergoing POP surgery do not have the daily activities of living to perform the pad test. Therefore, we examined whether the International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF) could be used as an alternative tool for pad tests.</p><p><strong>Methods: </strong>We retrospectively evaluated 132 patients with POP. In our hospital, 57 patients were treated by laparoscopic sacrocolpopexy (LSC), whereas 75 were treated by transvaginal mesh surgery (TVM). We measured the changes in symptoms preand postoperatively using the ICIQ-SF and 1-hour pad weight testing, and investigated the correlation between the total plus component question scores of the ICIQ-SF and 1-hour pad weight.</p><p><strong>Results: </strong>The preoperative ICIQ total scores in all patients decreased significantly as the amount of leakage on the 1-hour pad weight decreased. The component question scores also decreased significantly with decreasing levels of 1-hour pad weight. The LSC and TVM groups had decreased ICIQ-SF total and component question scores as pad weight decreased. At 12 months postoperatively, the ICIQ total scores in all patients significantly declined as the amount of leakage on the 1-hour pad weight decreased. In the LSC group, the ICIQ-SF total and component question scores also decreased with decreased pad weight, but the differences were not always significant between ICIQ scores and pad weight. In the TVM group, the ICIQ-SF total and component question scores also significantly decreased as the pad weight decreased.</p><p><strong>Conclusion: </strong>The ICIQ-SF could be an appropriate substitute for the 1-hour pad weight testing in predicting the severity of urinary incontinence. In the future, we hope to predict the level of urine leakage based on the ICIQ-SF score.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 3","pages":"215-224"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11450242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Public Perceptions of Enuresis: Insights From Online Communities in South Korea and the United States.","authors":"Jung Eun Yu, Kwang Jin Ko, Jung Yoon Kim","doi":"10.5213/inj.2448318.159","DOIUrl":"10.5213/inj.2448318.159","url":null,"abstract":"<p><strong>Purpose: </strong>To establish a foundation for raising awareness and disseminating accurate information about enuresis-one of the most challenging conditions to discuss openly-this paper examines public perceptions of enuresis.</p><p><strong>Methods: </strong>This paper collected title and text data from posts related to enuresis on the top popular online platforms such Naver Cafe in South Korea and Reddit in the United States (US). The data along with the thematic subcommunities where the posts were uploaded, was analyzed and visualized using word cloud, Latent Dirichlet Allocation (LDA) topic modeling, and pyLDAvis.</p><p><strong>Results: </strong>The findings reveal both similarities and differences in how the patients from the 2 countries addressed enuresis online. In both countries, enuresis symptoms were a daily concern, and individuals used online platforms as a space to talk about their experiences. However, South Koreans were more inclined to describe symptoms within region-based communities or mothers' forums, where they exchanged information and shared experiences before consulting a doctor. In contrast, US patients with medical experience or knowledge frequently discussed treatment processes, lifestyle adjustments, and medication options.</p><p><strong>Conclusion: </strong>South Koreans tend to be cautious when selecting and visiting hospitals, often relying on others for advice and preparation before seeking medical attention. Compared to online communities in the US, Korean users are more likely to seek preliminary diagnoses based on nonprofessional opinions. Consequently, it is important to lower the barriers for patients to access professional medical advice to mitigate the potential harm of relying on nonprofessional opinions. Additionally, there is a need to raise awareness so that adults can recognize and address their symptoms in a timely manner.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 3","pages":"239-249"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11450238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serious Games as a Therapeutic Tool in Pediatric Urology: A Review of Current Applications and Future Directions.","authors":"Hyung Jun Park, Eun Joung Kim, Jung Yoon Kim","doi":"10.5213/inj.2448322.161","DOIUrl":"10.5213/inj.2448322.161","url":null,"abstract":"<p><p>This paper examines the use of serious games that integrate engaging gameplay with educational and therapeutic benefits with a particular focus on their application in urology. The study reviews both domestic and international cases to evaluate the current practices and implications of these digital therapies. While serious games have been widely utilized in the treatment of pediatric cancer and psychiatric disorders-areas that require long-term care and management-their application in urology, in particular pediatric urology, has been limited. Although digital therapies like serious games are still emerging in the field of urology, they hold promise as effective supplements to traditional treatments while offering new options for managing a range of urological conditions. Pediatric conditions such as bedwetting, urinary incontinence, and dysuria, which often benefit from long-term training and habit formation, are particularly well-suited to this approach. By helping pediatric patients better understand and manage their symptoms, serious games can play a supportive role in the treatment process and have shown positive medical outcomes. This paper reviews the definitions and therapeutic effects of serious games, analyzes their current use in the medical field, and argues for their increased application in treating pediatric urinary conditions.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 3","pages":"185-195"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11450244/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term Outcomes of Periurethral Sphincter Botulinum Toxin in Female Chronic Urinary Retention.","authors":"Sarah L Wright, Piriyankan Ananthavarathan, Sara Simeoni, Prasad Malladi, Mahreen Pakzad, Jalesh N Panicker","doi":"10.5213/inj.2448176.088","DOIUrl":"10.5213/inj.2448176.088","url":null,"abstract":"<p><strong>Purpose: </strong>Nonneurogenic chronic urinary retention is an uncommon problem in young female individuals, and a well characterised causes is Fowler syndrome (primary disorder of urethral sphincter relaxation). Intermittent catheterisation is often challenging, and gold standard treatment sacral neuromodulation is not widely available. Urethral sphincter botulinum toxin injection has been shown to be effective cross-sectionally, however little is known about long-term outcomes.</p><p><strong>Methods: </strong>Female individuals presenting with urinary retention due to Fowler syndrome were reviewed retrospectively from a single tertiary referral centre over an 11-year period (2010-2021). One hundred units of onabotulinum toxin A (BoTX-A) was injected into the striated urethral sphincter in a divided dose by the periurethral approach. Efficacy and side effects were assessed 4 weeks after injection.</p><p><strong>Results: </strong>Thirty-three female individuals with a mean age of 40.1±14.1 years received 165 unique urethral sphincter BoTX-A injections over 11 years. Nineteen individuals (57.6%) presented in acute urinary retention, and 28 (84.8%) were reliant on catheterisation. Twenty-one individuals (64%) responded to BoTX-A injections and had a significantly raised baseline maximum urethral closure pressure (MUCP), compared to nonresponders (114.6 cm H2O, P=0.012). Side effects were reported following 19 injections (11.5%) however, were mild and transient. Fifteen individuals received more than 1 botulinum toxin injection (median, 3 injections), with a median interval of 112 days (interquartile range) and efficacy persisted following repeat injections and no safety concerns were seen.</p><p><strong>Conclusion: </strong>Sphincter botulinum toxin through the periurethral approach is safe and effective following repeat injections, and offers a low-cost, minimally invasive alternative to managing female chronic urinary retention due to Fowler syndrome, particularly when there was a high baseline MUCP.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 3","pages":"207-214"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11450239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Integral Theory, Pelvic Floor Biomechanics, and Binary Innervation.","authors":"Jörgen Quaghebeur, Peter Petros, Jean-Jacques Wyndaele, Stefan De Wachter","doi":"10.5213/inj.2448092.046","DOIUrl":"10.5213/inj.2448092.046","url":null,"abstract":"<p><p>The pelvic floor biomechanics and sphincter functioning are essential for understanding pelvic floor dysfunction and the pathophysiology of the pelvic organs. The pelvic floor consists of muscles, fascial connections and ligaments. The Integral Theory Paradigm (ITP) explains the musculoskeletal entity of the sphincter mechanism and the pathophysiology of pelvic organ function. The ITP explains the pelvic floor function determined by 3 directional muscle forces: forward, backwards and downward-acting muscle vector forces that form an anterior and posterior resultant. The resultant equilibrium is essential for urinary continence, voiding and defecation. Loose ligaments disturb the equilibrium of the pelvic floor's muscular function with consequences for the organ function's continence, evacuation, and sensory perception.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 3","pages":"181-184"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11450246/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urodynamic and Frequency-Volume Chart Parameters Influencing Anticholinergic Resistance in Patients With Neurogenic Detrusor Overactivity.","authors":"Ilker Akarken, Huseyin Tarhan, Hayrettin Sahin","doi":"10.5213/inj.2448310.155","DOIUrl":"10.5213/inj.2448310.155","url":null,"abstract":"<p><strong>Purpose: </strong>Neurogenic detrusor overactivity (NDOA) is characterized by involuntary detrusor muscle contractions during bladder filling in patients with neurological disorders. Anticholinergic therapy is the primary treatment; however, the reasons for treatment resistance in NDOA are not well understood. This study aimed to identify predictors of treatment failure by comparing urodynamic and frequency-volume chart data between patients with NDOA who respond and patients who do not respond to anticholinergic therapy.</p><p><strong>Methods: </strong>We reviewed the records of 362 patients presenting with lower urinary tract symptoms and selected 85 who had NDOA and were on anticholinergic therapy. Ultimately, 67 patients were analyzed. We categorized these individuals into responders (group R) and nonresponders (group NR) based on clinical and urodynamic improvements. Three-day frequencyvolume charts and urodynamic study results were retrospectively reviewed.</p><p><strong>Results: </strong>Of the 85 initial patients, 12 refused medication, and 6 were lost to follow-up. Pre- to posttreatment changes differed significantly between groups in the number of urgency urinary incontinence (UUI) episodes per 24 hours (P=0.001), maximum cystometric capacity (mL, P=0.003), NDOA frequency (P=0.004), and bladder compliance (mL/cm H2O, P=0.003). Multivariate analysis revealed that NDOA frequency (P=0.014) and UUI episodes per 24 hours (P=0.002) were significant factors associated with treatment failure.</p><p><strong>Conclusion: </strong>NDOA varies according to underlying neurological conditions. The frequencies of UUI episodes and NDOA in urodynamic studies can predict resistance to initial anticholinergic treatment.</p>","PeriodicalId":14466,"journal":{"name":"International Neurourology Journal","volume":"28 3","pages":"232-238"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11450240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}