{"title":"Graham-Little-Piccardi-Lassueur Syndrome with Mucosal Involvement: A Rare Case.","authors":"Rutoo Vipulkumar Polra, Jinal Jainendrabhai Tandel, Pragya Ashok Nair","doi":"10.4103/ijt.ijt_88_22","DOIUrl":"10.4103/ijt.ijt_88_22","url":null,"abstract":"<p><p>Graham-Little-Piccardi-Lassueur syndrome (GLPLS) is a type of lichen planopilaris. It mainly affects females aged 40-60 years. It is characterized by the triad of patchy cicatricial alopecia of the scalp, noncicatricial alopecia of the axilla and groin and a follicular spinous papule on the body, scalp, or both. The diagnosis is based on clinicopathological correlation. Different modalities of treatment are available with unsatisfactory responses, so early diagnosis is necessary to prevent progression and scarring alopecia. A case of GLPLS with classical features on clinical, dermoscopic, and histopathological examination is presented in a 73-year-old female.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"15 6","pages":"251-254"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588195/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142728708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V M Varsha Gowda, Shrutakirthi D Shenoi, Shamshad Ahmed Khan, Ganga Surpur
{"title":"Alopecia Areata with Renal Dysgenesis.","authors":"V M Varsha Gowda, Shrutakirthi D Shenoi, Shamshad Ahmed Khan, Ganga Surpur","doi":"10.4103/ijt.ijt_10_23","DOIUrl":"10.4103/ijt.ijt_10_23","url":null,"abstract":"","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"15 6","pages":"258-259"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588193/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142728705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mucinous Lupus Alopecia with Papulonodular Mucinosis as a Sole Cutaneous Manifestation of Systemic Lupus Erythematosus.","authors":"Mnainder Kaur, Kanika Roy, Dinesh P Asati, Tanya Sharama, Suman Patra","doi":"10.4103/ijt.ijt_75_22","DOIUrl":"10.4103/ijt.ijt_75_22","url":null,"abstract":"","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"15 6","pages":"255-257"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588190/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142728711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tofacitinib in the Management of Alopecia Universalis.","authors":"Prashant Agarwal","doi":"10.4103/ijt.ijt_77_23","DOIUrl":"10.4103/ijt.ijt_77_23","url":null,"abstract":"<p><p>Alopecia universalis (AU) is a rare form of hair loss characterized by the complete absence of hair on the scalp and body. It is an advanced form of alopecia areata. There is currently no definitive treatment for this condition, and management options are limited. This case report describes the successful treatment of a 37-year-old female patient with AU using oral tofacitinib 5 mg BID, an oral Janus kinase inhibitor. The patient experienced clinically significant hair regrowth on the scalp and eyebrows after 6 months of treatment with tofacitinib, along with the concurrent use of oral mini-pulse betamethasone, topical minoxidil 5%, and clobetasol lotion. This case highlights the potential efficacy of tofacitinib as a promising therapeutic option for AU, without notable safety concerns. Moreover, it is also well tolerated in this patient.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"15 5","pages":"194-196"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11335045/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oral Vitamin D Treatment in Patients with Telogen Effluvium: Clinical and Dermoscopic Evaluation.","authors":"Rania Ahmed El-Tatawy, Shereen Gheida, Ghada Adbel Moamen Soliman, Mayada Ismail","doi":"10.4103/ijt.ijt_92_22","DOIUrl":"10.4103/ijt.ijt_92_22","url":null,"abstract":"<p><strong>Background: </strong>Telogen effluvium (TE) is the most common hair loss. Vitamin D is related to hair and skin diseases due to its immunomodulatory and anti-inflammatory effects.</p><p><strong>Objective: </strong>To investigate Vitamin D serum level role in TE pathogenesis.</p><p><strong>Patients and methods: </strong>Forty females with TE were collected and twenty age- and sex-matched healthy individuals as controls. Serum 25(OH) Vitamin D level was estimated prior and 3 months after oral Vitamin D.</p><p><strong>Results: </strong>The mean serum 25(OH) Vitamin D levels were significantly lower in TE patients than controls (13.31 ± 5.8 ng/ml vs. 33.61 ± 8.16 ng/ml) respectively, <i>P</i> < 0.001. The mean serum 25(OH) Vitamin D levels before treatment in acute TE was 12.31 ± 6.88 ng/ml, compared to 10.6 ± 3.9 ng/ml in chronic TE without a significant difference, (<i>P</i> = 0.544). The mean serum 25(OH) Vitamin D levels in TE group after 3 months oral Vitamin D therapy were 38.4 ± 15.22 ng/ml with significant increase compared to pretreatment level, (<i>P</i> < 0.001). However, without a significant difference between acute TE (45.4 ± 9.22 ng/ml) and chronic TE (42.1 ± 10.6 ng/ml), (<i>P</i> = 0.711).</p><p><strong>Conclusion: </strong>Oral Vitamin D has a promising effect in TE treatment, but the results need to be verified on a larger scale with evidence-based recommendation regarding the exact dose and treatment duration.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"15 5","pages":"183-190"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11335050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinicopathology, Trichoscopy, and Treatment Responsiveness of Folliculitis Decalvans: A Case Series of Three Pediatric Cases.","authors":"Vidya Yadav, Apaopa Jemima Thekho, Vibhu Mendiratta, Md Ali Osama, Smita Singh","doi":"10.4103/ijt.ijt_109_22","DOIUrl":"10.4103/ijt.ijt_109_22","url":null,"abstract":"","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"15 5","pages":"213-217"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11335047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Güllü Gencebay, Özge Aşkin, Övgü Aydin, Server Serdaroğlu
{"title":"The Association between Number of Follicular Stelae and Severity and Treatment Response of Alopecia Areata Cases: A Retrospective Study.","authors":"Güllü Gencebay, Özge Aşkin, Övgü Aydin, Server Serdaroğlu","doi":"10.4103/ijt.ijt_76_21","DOIUrl":"10.4103/ijt.ijt_76_21","url":null,"abstract":"<p><strong>Background: </strong>Alopecia areata (AA) is an autoimmune disease characterized by peribulbar lymphocytic infiltration, follicular miniaturization, catagen/telogen follicles, and increased follicular stelae (streamers) in skin biopsies.</p><p><strong>Objectives: </strong>Our aim was to assess the number of follicular stelae of patients with AA and to evaluate their association with clinical type and severity and treatment response of AA.</p><p><strong>Materials and methods: </strong>Histopathologic features including the number of follicular stelae were recorded in skin biopsies taken from lesions of AA in 142 patients who attended our dermatology clinic from 2011 to 2017.</p><p><strong>Results: </strong>There was a statistically significant correlation between patient age and the number of follicular stelae (<i>P</i> = 0.001). There was a statistically significant correlation between the severity of disease and number of follicular stelae (<i>P</i> = 0.005). AA subtypes (0%-25% scalp hair loss) had a significantly lower number of follicular stelae than 75%-100% of scalp hair loss and alopecia universalis (7.92 ± 4.21 vs. 13.23 ± 7.28). There was no statistically significant correlation between treatment response and the number of follicular stelae (<i>P</i> = 0.75).</p><p><strong>Conclusion: </strong>Our results showed that the number of follicular stelae varied among AA clinical types and correlated with severity. This study was the first to evaluate the correlation between the number of follicular stelae and severity of AA.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"15 5","pages":"191-193"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11335049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison among Intense Pulsed Light, Alexandrite, and Long-Pulsed Neodymium-Doped Yttrium Aluminum Garnet 1064 Nm Lasers for Lower Leg Hair Removal: Case Series.","authors":"Indri Widya Sari, Yuli Kurniawati, Sarah Diba","doi":"10.4103/ijt.ijt_110_21","DOIUrl":"10.4103/ijt.ijt_110_21","url":null,"abstract":"<p><p>Lower leg hair removal is the method of reducing unwanted lower leg hair. Various technologies for lower leg hair removal include Intense Pulsed Light (IPL), alexandrite laser, and neodymium-doped yttrium aluminum garnet (Nd: YAG) laser. Conventional techniques are abandoned because effectiveness of the latest technological therapies has a longer period with minimal side effects. The comparison of successful treatment among IPL, alexandrite laser, and Nd: YAG laser for lower leg hair removal. Two patients, male and female, 28 years old, Fitzpatrick IV skin type. Three areas in the lower legs are marked for IPL 695 nm, <i>fluence</i> 15 J/cm<sup>2</sup>, <i>pulse duration</i> 60 ms; alexandrite 755 nm, <i>fluence</i> 3 J/cm<sup>2</sup>, <i>pulse duration</i> 2 ms, long-pulsed Nd: YAG 1064 nm, <i>fluence</i> 32 J/cm<sup>2</sup>, <i>pulse duration</i> 60 ms. IPL for 3 sessions at 2-week intervals. The alexandrite and Nd: YAG lasers for 3 sessions at 4-week intervals. Successful parameters with hair reduction and Visual Analog Scale (VAS) can be seen from photography and dermoscopy before and after therapy. In the first case, the most effective reduction terminal hair after IPL (95,1%), alexandrite (91,02%) and Nd: YAG (79,69%), respectively. In the second case, the most effective reduction of terminal hair after alexandrite (91,02%), Nd: YAG (79,69%), and IPL (20%), respectively. Hyperpigmentation and the highest VAS score (6-7) are found in the area treated with alexandrite lasers of two patients. Two patients have decreased Dermatology Life Quality Index scores. Nd: YAG laser may be better suitable for both sexes with minimal side effects. The limitation of this study is the smaller subject group and limited session.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"15 5","pages":"197-203"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11335051/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Symmetric Idiopathic MicroPapular Facial Eruption or SIMPLE - Description of a New Entity Featuring Facial Vellus Hair Lichen Planopilaris in the Absence of Frontal Fibrosing Alopecia.","authors":"Vishal Madan","doi":"10.4103/ijt.ijt_107_22","DOIUrl":"10.4103/ijt.ijt_107_22","url":null,"abstract":"<p><p>Patients with frontal fibrosing alopecia (FFA) can present with facial micropapules which histologically represent vellus hair lichen planopilaris (LPP). Noninflammatory vellus hair LPP in the absence of FFA is rarely reported. The report describes noninflammatory vellus hair LPP presenting as symmetrical facial micropapules in the absence of clinical signs of FFA.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"15 5","pages":"208-212"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11335046/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Targetoid Hair Regrowth Pattern in Alopecia Areata: A Case Series.","authors":"Heera Ramesh, Sachin Somashekhar, Kanathur Shilpa","doi":"10.4103/ijt.ijt_48_22","DOIUrl":"10.4103/ijt.ijt_48_22","url":null,"abstract":"<p><p>Alopecia areata (AA) is an autoimmune disorder leading to nonscarring hair loss of the scalp and/or body. Atypical hair regrowth in AA is considered a rare phenomenon. Many paradoxical forms of hair regrowth have been described in AA. Targetoid hair regrowth pattern in AA was first described in 1988. Here, we report three cases wherein this pattern of hair regrowth was seen.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"15 5","pages":"204-207"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11335048/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}