International Journal of Trichology最新文献

{"title":"Determination of Force Exerted During Pull Test.","authors":"S Nithya, C R Srinivas, C K Nair Shashidharan","doi":"10.4103/ijt.ijt_82_22","DOIUrl":"https://doi.org/10.4103/ijt.ijt_82_22","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this was to determine the force exerted during the pull test using a hand-held spring balance.</p><p><strong>Materials and methods: </strong>A hand-held spring balance was used to determine the force exerted during pull test. Ten volunteers performed the test five times each, and the mean was recorded as the force exerted by each volunteer.</p><p><strong>Results: </strong>A total of 10 volunteers were included in the study. The mean value of the force exerted by the volunteers was 0.25 N (Newton).</p><p><strong>Conclusion: </strong>Using the spring balance, we attempted to measure the force used while performing the pull test, which may help in standardizing the hair pull test. Further experiments are being undertaken to determine the grasping force exerted during pull test. These two forces when combined in an instrument will enable us to overcome the individual investigator variability while performing the test.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"13-15"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Remission with Combination of Diphenylcyclopropenone and Apremilast in Refractory Extensive Alopecia Areata.","authors":"Siddhi B Chikhalkar, Savera Gupta, Snehal Umesh Chopade, Sushanti Jadhav, Vidya Kharkar","doi":"10.4103/ijt.ijt_68_22","DOIUrl":"https://doi.org/10.4103/ijt.ijt_68_22","url":null,"abstract":"<p><p>Extensive alopecia areata including alopecia totalis and alopecia universalis is a therapeutic challenge in majority of the cases due to poor response to therapy, frequent relapses, minimal chances of spontaneous remission, and the associated psychological distress. Topical immunotherapy with diphenylcyclopropenone (DPCP) is one of the established therapeutic modalities for alopecia areata, although with a variable response rate. The use of systemic corticosteroids and other immunosuppressive drugs such as cyclosporine, azathioprine, and methotrexate is limited by their side effects. Apremilast, a phosphodiesterase-4 inhibitor, marked with a high safety profile and minimal monitoring, has been used off-label in many dermatological conditions including alopecia areata. We report three cases of extensive refractory alopecia areata with successful remission following combination therapy of DPCP and apremilast.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"47-49"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039770/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traction Folliculitis: An Unrecognized Entity.","authors":"Damini Arora, Pooja Arora, Purnima Paliwal, Sunayana Misra","doi":"10.4103/ijt.ijt_81_21","DOIUrl":"https://doi.org/10.4103/ijt.ijt_81_21","url":null,"abstract":"<p><p>Traction folliculitis (TF) is an uncommon and under-reported entity that presents as perifollicular erythema and pustules in patients in whom excessive traction is used while styling the hair. In this article, we report 2 patients who presented with TF subsequent to excessive traction while tying the hair. In both these patients, the condition improved with change of hairstyle.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"39-41"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039776/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Apocrine Hidrocystoma: A Rare Benign Cystic Skin Tumor at Uncommon Site.","authors":"Sushma Bharti, Jyotsna Naresh Bharti, R Madhubala, Prabin Kumar","doi":"10.4103/ijt.ijt_76_20","DOIUrl":"https://doi.org/10.4103/ijt.ijt_76_20","url":null,"abstract":"<p><p>Apocrine hidrocystoma (AH) is an uncommon benign cystic tumor, which arises from the apocrine secretory coil. The lesion is usually single and commonly seen over the face or scalp. It rarely involves the genitalia and if ever seen, then it occurs in foreskin followed by the shaft of the penis. AH commonly affects adults with equal gender incidence. Histopathological confirmation is done by the presence of cystic spaces in the dermis lined by bilaminar epithelium, outer myoepithelial cells and inner columnar, and eosinophilic cells with basally positioned nuclei, and often prominent apical snouts are also noted. It should be differentiated from other cystic lesions over the penile shaft. The treatment of choice is the complete excision. To date, only 13 cases of genital AH have been reported. Among that, very few cases have been reported over the penile shaft. Herein, we emphasize the importance of considering the differential diagnosis of the cystic lesion over the penile shaft.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"52-54"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Topical Glycosaminoglycan Lotion and Microneedling Therapy for Androgenetic Alopecia.","authors":"O M Moreno-Arrones, P Fernandez-Gonzalez, P Jaen, S Vañó-Galván","doi":"10.4103/ijt.ijt_66_22","DOIUrl":"https://doi.org/10.4103/ijt.ijt_66_22","url":null,"abstract":"","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"16 1-6","pages":"65-66"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12039777/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare Association of Congenital Atrichia with Central Nervous System: A Report of Three Cases.","authors":"Suman Swamynathan, Sahana M Srinivas, Hania Qamar Khan","doi":"10.4103/ijt.ijt_58_21","DOIUrl":"10.4103/ijt.ijt_58_21","url":null,"abstract":"<p><p>Congenital atrichia a rare form of alopecia in children, presents with complete absence or sparse hair over the scalp and body, while the teeth, nails, and sweat glands are normal. Uncommonly, this hair abnormality can be associated with any systemic or cutaneous abnormalities. We report three cases of congenital atrichia with parental nonconsanguinity and central nervous associations such as developmental delay,spastic quadriparesis, failure to thrive, myoclonic seizures, and attention deficit hyperactivity disorder. The presence of papular lesions in two among the three children further supplemented our case report. Genetic analysis and counseling regarding the constancy of the condition will be the foremost important part of management.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"15 6","pages":"248-250"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142728714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Paper Sign Test - Assessment, Evaluation, and Diagnosis Method for Reactivated Lichen Planopilaris by Physician and Patient.","authors":"Ali Abbasi, Ramin Rabani, Kambiz Kamyab, Hamidreza Mahmoudi","doi":"10.4103/ijt.ijt_177_20","DOIUrl":"10.4103/ijt.ijt_177_20","url":null,"abstract":"<p><strong>Background: </strong>Lichen planopilaris (LPP) is an inflammatory disease that results in destruction of the hair follicle and replaces it with patchy permanent scarring alopecia; after stabilizing by treatment, reactivation is common and may be insidious. During remission, various methods are available for realizing that the disease is activated or not, but neither of them is practical for patients.</p><p><strong>Objectives: </strong>This study aims to evaluate the paper sign test for reactivated LPP by physician and patient.</p><p><strong>Patients and methods: </strong>In a prospective study, during 2 years, 83 treated LPP patients have been divided into two groups of 41 and 42. Group 1 instructed for paper sign test which is to comb their hair over a white paper sheet to catch any fallen hairs, then turn the paper upside down, if all collected hair on paper completely separated, test is considered negative, if even one hair hangs onto the paper, the test is considered positive. Group 2 trained for clinical symptoms (hair shedding, scaling, itching, pain, tenderness, and burning).</p><p><strong>Results: </strong>From the first group, 13 patients had positive paper sign, and from the second group, 35 patients had clinical symptoms; after clinical examination and biopsy, 13 from Group 1 and 17 from Group 2 were confirmed to have reactivated disease. Patients in the first group who had been trained for paper sign test became aware of relapse sooner and came earlier for the evaluation of disease.</p><p><strong>Conclusion: </strong>Paper sign test is a reliable, noninvasive, and practical test for early detection of reactivated LPP by patients during remission period.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"15 6","pages":"236-240"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588194/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142728722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Study of Serum Ferritin and Thyroid-Stimulating Hormone Levels in Male Patients with Androgenetic Alopecia.","authors":"Pallakshi Prasad, Preema Sinha, Nagendra Singh Beniwal, Rajesh Sahu","doi":"10.4103/ijt.ijt_103_22","DOIUrl":"10.4103/ijt.ijt_103_22","url":null,"abstract":"<p><strong>Background: </strong>Androgenetic alopecia (AGA) is a multifactorial disorder expressed by several genes and various environmental factors apart from nutritional and endocrinological factors. Although association of iron deficiency (ID) as well as thyroid disorder has been evaluated in females, this is still an untouched topic as far as male pattern hair loss (MPHL) is concerned. This study tries to establish if any association of MPHL with ID and thyroid dysfunction.</p><p><strong>Materials and methods: </strong>This case-control study comprised 30 consecutive cases of MPHL and equal numbers of age-matched healthy controls attending dermatology outdoor department at a tertiary care hospital. Cases as well as controls were evaluated and screened for the levels of serum ferritin (SF) and thyroid-stimulating hormone (TSH). Value of SF (8-388 ng/mL) and TSH (0.358-3.7 uIU/mL) was used as standardized reference.</p><p><strong>Results: </strong>In cases of AGA, SF level varied from 6.00 to 212.09 ng/mL (mean - 88.30 ng/mL). Whereas controls showed SF levels ranging between 23.67 and 185.05 ng/mL (mean 78.69 ng/mL). The range of TSH level in the case group was 0.379-5.078 uIU/L (mean 2.25 uIU/L), respectively, whereas control group showed serum TSH levels ranging between 0.30 and 4.30 uIU/L (mean - 1.78 uIU/L). Statistically considering two samples of equal variance <i>P</i> (2-tailed) for SF level was found to be 0.424, whereas 0.085 in case of TSH level depicting insignificant association. Spearman's correlations (<i>P</i> = 0.244) between alopecia grade and SF level were found to be statistically insignificant (<i>P</i> = 0.193). Similarly, the <i>P</i> value calculated for the alopecia grade and serum TSH was 0.784, making the correlation between alopecia and serum TSH as insignificant.</p><p><strong>Conclusion: </strong>The study found no statistically significant difference in the SF level and TSH level of the cases as compared to controls.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"15 6","pages":"231-235"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142728702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Cross-sectional Observational Study to Correlate the Trichoscopic Findings of Female Pattern Hair Loss with the Disease Severity and Underlying Histopathological Changes.","authors":"Shreya Singh, Meena B Makhecha, Kinjal Deepak Rambhia","doi":"10.4103/ijt.ijt_40_22","DOIUrl":"10.4103/ijt.ijt_40_22","url":null,"abstract":"<p><strong>Background: </strong>The increasing prevalence of female pattern hair loss (FPHL) is an alarming concern. Trichoscopy is an important bedside diagnostic tool for the diagnosis of FPHL, but there are very few studies correlating it with disease severity or histopathological findings which would provide a better insight to the treating clinician. Hence, we decided to take up this study.</p><p><strong>Aim: </strong>This study aimed to study the trichoscopic findings of FPHL and correlate their relationship with disease severity and histopathological finding in our tertiary care hospital.</p><p><strong>Materials and methods: </strong>Ninety females attending the dermatology outpatient department who were clinically diagnosed with FPHL were included in the study after informed consent and clearance from the institutional ethics committee. This was followed by a detailed history, clinical examination, and trichoscopic assessment. A trichoscopy-guided biopsy was performed from two sites. After the data collection, the statistical software used was IBM SPSS version 21.0 and Microsoft Office Excel 2007. <i>P</i> < 0.05 was accepted as indicative of statistical significance.</p><p><strong>Results: </strong>Anisotrichosis, increased interfollicular distance, and decreased hairs per follicular unit were universal. Brown peripilar sign had a positive association with inflammation (<i>P</i> < 0.0005) and white peripilar sign with duration of disease and fibrosis whereas dartboard sign had a significant association with inflammation as well as fibrosis.</p><p><strong>Conclusion: </strong>Trichoscopy helps in diagnosing the condition, assessing the severity, and monitoring the response to treatment. A knowledge about the features underlying specific trichoscopic signs such as inflammation and fibrosis would help the clinician decide the line of management.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"15 6","pages":"221-230"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588189/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142728699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TH07 - A New Novel Topical Treatment for Androgenic Alopecia.","authors":"Houfar Sekhavat, Peter Ford, Anik Lepage, Ariana Nateghi, Sara Bar Yehuda, Marianne Bourgeois","doi":"10.4103/ijt.ijt_145_22","DOIUrl":"10.4103/ijt.ijt_145_22","url":null,"abstract":"<p><strong>Objectives: </strong>Androgenic alopecia (AGA) is common among men. Currently, topical minoxidil and oral finasteride are approved by the FDA for the treatment of AGA. Unfortunately, neither of them is completely effective and systemic adverse events have been reported after finasteride administration. Triple Hair Inc. has developed a new topical treatment regimen using a combination of finasteride, latanoprost and minoxidil - TH07. Each of the compounds was effective and safe as a topical treatment in animal models and clinical studies of AGA. The aim of this proof-of-concept study was to evaluate the effectiveness of the TH07 in comparison to the 3 drugs as monotherapy on hair growth in men with AGA.</p><p><strong>Methods: </strong>Patients with light to moderate AGA were randomized to be treated topically, once daily, for 6 months with TH07, 0.1% finasteride, 0.03% latanoprost, or 5% minoxidil. Data of investigators' assessment based on pictures, as well as patients' self-assessment and satisfaction, were collected.</p><p><strong>Results: </strong>A moderate hair re-growth in the majority of the participant treated with TH07 in comparison to the retreatment with its active components administered as monotherapy was reported by the investigators. Most of the patients treated with TH07 were satisfied with their hair appearance in comparison to the other treatments. No systemic adverse events were reported and the TH07 was well tolerated.</p><p><strong>Conclusions: </strong>The data of the current study demonstrated that the topical administration of TH07 resulted in an improved efficacy in the treatment of the AGA compared to treatment with each of the ingredients administered separately.</p>","PeriodicalId":14417,"journal":{"name":"International Journal of Trichology","volume":"15 6","pages":"241-247"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142728717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}